+D Chaperone KO
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Chaperones and Folding Catalysts - Nicrophorus vespilloides (burying beetle)
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AHeat shock proteins
B HSP110
C 108556328 heat shock 70 kDa protein 4 K09485 HSP110; heat shock protein 110kDa
C 108559409 hypoxia up-regulated protein 1 K09486 HYOU1; hypoxia up-regulated 1
B HSP100
C 108569824 caseinolytic peptidase B protein homolog K03695 clpB; ATP-dependent Clp protease ATP-binding subunit ClpB
C 108561401 ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial isoform X1 K03544 clpX; ATP-dependent Clp protease ATP-binding subunit ClpX
B HSP90
C 108558833 heat shock protein 83 K04079 HSP90A; molecular chaperone HtpG
C 108566806 endoplasmin K09487 HSP90B; heat shock protein 90kDa beta
C 108569893 heat shock protein 75 kDa, mitochondrial K09488 TRAP1; TNF receptor-associated protein 1
B HSP70 / DNAK
C 108556491 heat shock 70 kDa protein cognate 2-like K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 108564316 78 kDa glucose-regulated protein homolog K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 108564553 heat shock 70 kDa protein cognate 4 K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 108564555 heat shock 70 kDa protein 1A-like K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 108569718 heat shock protein 70 A1-like K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 108558503 heat shock protein 68-like K03283 HSPA1_6_8; heat shock 70kDa protein 1/6/8
C 108557894 LOW QUALITY PROTEIN: heat shock 70 kDa protein cognate 3 K09490 HSPA5; endoplasmic reticulum chaperone BiP [EC:3.6.4.10]
C 108567647 heat shock 70 kDa protein cognate 5 K04043 dnaK; molecular chaperone DnaK
B HSP60 / Chaperonin
C 108568859 T-complex protein 1 subunit alpha K09493 CCT1; T-complex protein 1 subunit alpha
C 108567575 T-complex protein 1 subunit beta K09494 CCT2; T-complex protein 1 subunit beta
C 108567849 T-complex protein 1 subunit gamma K09495 CCT3; T-complex protein 1 subunit gamma
C 108561521 T-complex protein 1 subunit delta K09496 CCT4; T-complex protein 1 subunit delta
C 108558164 T-complex protein 1 subunit epsilon K09497 CCT5; T-complex protein 1 subunit epsilon
C 108557298 T-complex protein 1 subunit zeta K09498 CCT6; T-complex protein 1 subunit zeta
C 108560351 T-complex protein 1 subunit eta K09499 CCT7; T-complex protein 1 subunit eta
C 108565891 T-complex protein 1 subunit theta K09500 CCT8; T-complex protein 1 subunit theta
C 108557652 60 kDa heat shock protein, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
B HSP47
B HSP40 / DNAJ
C 108567527 dnaJ homolog subfamily A member 1 K09502 DNAJA1; DnaJ homolog subfamily A member 1
C 108568925 dnaJ homolog subfamily A member 2-like K09503 DNAJA2; DnaJ homolog subfamily A member 2
C 108565099 protein tumorous imaginal discs, mitochondrial isoform X1 K09504 DNAJA3; DnaJ homolog subfamily A member 3
C 108556773 dnaJ homolog subfamily C member 21 K09506 DNAJA5; DnaJ homolog subfamily A member 5
C 108558573 dnaJ protein homolog 1 K09507 DNAJB1; DnaJ homolog subfamily B member 1
C 108562241 dnaJ homolog subfamily B member 6 isoform X1 K09512 DNAJB6; DnaJ homolog subfamily B member 6
C 108569122 dnaJ homolog subfamily B member 11 K09517 DNAJB11; DnaJ homolog subfamily B member 11
C 108569270 dnaJ homolog subfamily B member 12 K09518 DNAJB12; DnaJ homolog subfamily B member 12
C 108562626 dnaJ homolog subfamily B member 13 isoform X1 K09519 DNAJB13; DnaJ homolog subfamily B member 13
C 108568637 uncharacterized protein F54F2.9 K09521 DNAJC1; DnaJ homolog subfamily C member 1
C 108568528 dnaJ homolog subfamily C member 2 K09522 DNAJC2; DnaJ homolog subfamily C member 2
C 108569542 dnaJ-like protein 60 K09524 DNAJC4; DnaJ homolog subfamily C member 4
C 108560165 dnaJ homolog subfamily C member 5-like K09525 DNAJC5; DnaJ homolog subfamily C member 5
C 108568537 dnaJ homolog subfamily C member 5 isoform X1 K09525 DNAJC5; DnaJ homolog subfamily C member 5
C 108567991 dnaJ homolog subfamily C member 7 K09527 DNAJC7; DnaJ homolog subfamily C member 7
C 108558645 dnaJ homolog subfamily C member 8 K09528 DNAJC8; DnaJ homolog subfamily C member 8
C 108556501 J domain-containing protein CG6693-like K09529 DNAJC9; DnaJ homolog subfamily C member 9
C 108564899 dnaJ homolog subfamily C member 10-like K09530 DNAJC10; DnaJ homolog subfamily C member 10 [EC:1.8.4.-]
C 108569216 dnaJ homolog subfamily C member 11 K09531 DNAJC11; DnaJ homolog subfamily C member 11
C 108560097 J domain-containing protein K09532 DNAJC12; DnaJ homolog subfamily C member 12
C 108566042 dnaJ homolog subfamily C member 13 K09533 DNAJC13; DnaJ homolog subfamily C member 13
C 108557343 dnaJ homolog dnj-5 K09534 DNAJC14; DnaJ homolog subfamily C member 14
C 108568980 dnaJ homolog subfamily C member 16 K09536 DNAJC16; DnaJ homolog subfamily C member 16
C 108559061 dnaJ homolog subfamily C member 17 K09537 DNAJC17; DnaJ homolog subfamily C member 17
C 108562857 mitochondrial import inner membrane translocase subunit TIM14 K09539 DNAJC19; DnaJ homolog subfamily C member 19
C 108559082 dnaJ homolog subfamily C member 22 K19370 DNAJC22; DnaJ homolog subfamily C member 22
C 108562635 translocation protein SEC63 homolog K09540 SEC63; translocation protein SEC63
C 108568116 dnaJ homolog subfamily C member 25 homolog K19371 DNAJC25; DnaJ homolog subfamily C member 25
C 108558769 dnaJ homolog subfamily C member 28 K19373 DNAJC28; DnaJ homolog subfamily C member 28
C 108561137 dnaJ homolog subfamily C member 30-like K19374 DNAJC30; DnaJ homolog subfamily C member 30
C 108566243 iron-sulfur cluster co-chaperone protein HscB, mitochondrial K04082 hscB; molecular chaperone HscB
B HSP33
B HSP24
C 108564812 grpE protein homolog, mitochondrial K03687 GRPE; molecular chaperone GrpE
B HSP20
C 108568008 protein lethal(2)essential for life-like K09542 CRYAB; crystallin, alpha B
C 108568013 protein lethal(2)essential for life-like K09542 CRYAB; crystallin, alpha B
C 108568098 protein lethal(2)essential for life-like K09542 CRYAB; crystallin, alpha B
C 108568104 protein lethal(2)essential for life-like K09542 CRYAB; crystallin, alpha B
B HSP15
B HSP10
C 108567688 10 kDa heat shock protein, mitochondrial K04078 groES; chaperonin GroES
B GimC
C 108566213 prefoldin subunit 1 K09548 PFDN1; prefoldin subunit 1
C 108563852 prefoldin subunit 2 K09549 PFDN2; prefoldin subunit 2
C 108561403 prefoldin subunit 4 K09550 PFDN4; prefoldin subunit 4
C 108564759 prefoldin subunit 5 K04797 pfdA; prefoldin alpha subunit
C 108566485 prefoldin subunit 6 K04798 pfdB; prefoldin beta subunit
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AOther chaperones and cochaperones
B Calnexin / calreticulin
C 108562762 calnexin isoform X1 K08054 CANX; calnexin
C 108558199 calreticulin isoform X1 K08057 CALR; calreticulin
B DegP / HtrA
C 108558222 serine protease HTRA2, mitochondrial-like K08669 HTRA2; HtrA serine peptidase 2 [EC:3.4.21.108]
C 108561986 serine protease HTRA2, mitochondrial-like K08669 HTRA2; HtrA serine peptidase 2 [EC:3.4.21.108]
B AAA proteases
C 108560022 paraplegin K09552 SPG7; spastic paraplegia 7 [EC:3.4.24.-]
C 108561628 AFG3-like protein 2 K08956 AFG3; AFG3 family protein [EC:3.4.24.-]
B PapD
B SecB
B Sti1 / p60
C 108561829 stress-induced-phosphoprotein 1 K09553 STIP1; stress-induced-phosphoprotein 1
B Cdc37 / p50
C 108569176 hsp90 co-chaperone Cdc37 K09554 CDC37; cell division cycle protein 37
B BAG
C 108561213 BAG family molecular chaperone regulator 2 K09556 BAG2; BCL2-associated athanogene 2
C 108569740 BAG domain-containing protein Samui-like isoform X1 K09557 BAG3; BCL2-associated athanogene 3
B Others
C 108557872 putative protein FAM10A4 K09560 ST13; suppressor of tumorigenicity protein 13
C 108563525 E3 ubiquitin-protein ligase CHIP K09561 STUB1; STIP1 homology and U-box containing protein 1 [EC:2.3.2.27]
C 108568871 hsp70-binding protein 1 K09562 HSPBP1; hsp70-interacting protein
C 108562673 HSPB1-associated protein 1 K19375 HSPBAP1; HSPB1-associated protein 1
C 108557946 protein OPI10 homolog K23327 HIKESHI; protein Hikeshi
C 108560000 cysteine and histidine-rich domain-containing protein K16729 CHORDC1; cysteine and histidine-rich domain-containing protein
C 108566762 prolyl 3-hydroxylase 1-like K08134 P3H1; procollagen-proline 3-dioxygenase 1 [EC:1.14.11.7]
C 108561601 methyltransferase-like protein 23 K23151 METTL23; methyltransferase-like protein 23 [EC:2.1.1.-]
C 108565305 protein unc-45 homolog B K21991 UNC45; protein unc-45
C 108568779 protein canopy 4 K22816 CNPY3_4; protein canopy 3/4
C 108561394 torsin-1A-like K22990 TOR1; torsin-1
C 108564514 torsin-1A-like K22990 TOR1; torsin-1
C 108560442 SPARC K24262 SPARC; secreted protein acidic and rich in cysteine
C 108559220 small glutamine-rich tetratricopeptide repeat-containing protein beta-like K16365 SGTA; small glutamine-rich tetratricopeptide repeat-containing protein alpha
C 108558709 small glutamine-rich tetratricopeptide repeat-containing protein beta-like K24925 SGTB; small glutamine-rich tetratricopeptide repeat-containing protein beta
C 108557873 tetratricopeptide repeat protein 1 K24926 TTC1; tetratricopeptide repeat protein 1
C 108561199 tetratricopeptide repeat protein 4 K24927 TTC4; tetratricopeptide repeat protein 4
C 108568414 coiled-coil domain-containing protein 47 K24962 CCDC47; PAT complex subunit CCDC47
C 108563031 protein Asterix K24963 WDR83OS; PAT complex subunit Asterix
C 108564044 LDLR chaperone boca K25366 MESD; LRP chaperone MESD
C 108556776 uncharacterized protein LOC108556776 isoform X1 K26164 RIC3; protein RIC-3
C 108562298 activator of 90 kDa heat shock protein ATPase homolog 1 K26216 AHSA1; activator of Hsp90 ATPase protein 1
C 108556448 transmembrane protein 35 K26241 NACHO; novel acetylcholine receptor chaperone
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AIntramolecular chaperones
B Subtilisin family
C 108566486 membrane-bound transcription factor site-1 protease K08653 MBTPS1; membrane-bound transcription factor site-1 protease [EC:3.4.21.112]
C 108560582 furin-like protease 1 isoform X1 K01349 FURIN; furin [EC:3.4.21.75]
C 108559489 neuroendocrine convertase 1-like K01359 PCSK1; proprotein convertase subtilisin/kexin type 1 [EC:3.4.21.93]
C 108564649 neuroendocrine convertase 1-like K01359 PCSK1; proprotein convertase subtilisin/kexin type 1 [EC:3.4.21.93]
C 108562637 neuroendocrine convertase 2 K01360 PCSK2; proprotein convertase subtilisin/kexin type 2 [EC:3.4.21.94]
C 108561042 furin-like protease 2 K08654 PCSK5; proprotein convertase subtilisin/kexin type 5 [EC:3.4.21.-]
C 108556611 tripeptidyl-peptidase 2 K01280 TPP2; tripeptidyl-peptidase II [EC:3.4.14.10]
B Papain family
C 108557216 cathepsin B K01363 CTSB; cathepsin B [EC:3.4.22.1]
C 108563264 cathepsin L K01365 CTSL; cathepsin L [EC:3.4.22.15]
C 108563266 cathepsin L1-like K01365 CTSL; cathepsin L [EC:3.4.22.15]
B Other peptidases
B Others
C 108565424 chitooligosaccharidolytic beta-N-acetylglucosaminidase K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C 108559040 beta-hexosaminidase subunit beta-like K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
C 108559261 chitooligosaccharidolytic beta-N-acetylglucosaminidase K12373 HEXA_B; hexosaminidase [EC:3.2.1.52]
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AProtein folding catalysts
B Peptidyl prolyl isomerase
C Cyclophilin
D 108565287 peptidyl-prolyl cis-trans isomerase B-like K03768 PPIB; peptidyl-prolyl cis-trans isomerase B (cyclophilin B) [EC:5.2.1.8]
D 108559427 peptidyl-prolyl cis-trans isomerase D K05864 PPID; peptidyl-prolyl isomerase D [EC:5.2.1.8]
D 108561598 peptidyl-prolyl cis-trans isomerase E K09564 PPIE; peptidyl-prolyl isomerase E (cyclophilin E) [EC:5.2.1.8]
D 108561794 peptidyl-prolyl cis-trans isomerase-like K09565 PPIF; peptidyl-prolyl isomerase F (cyclophilin D) [EC:5.2.1.8]
D 108566248 peptidyl-prolyl cis-trans isomerase G K09566 PPIG; peptidyl-prolyl isomerase G (cyclophilin G) [EC:5.2.1.8]
D 108561814 peptidyl-prolyl cis-trans isomerase H K09567 PPIH; peptidyl-prolyl isomerase H (cyclophilin H) [EC:5.2.1.8]
D 108563497 LOW QUALITY PROTEIN: peptidyl-prolyl cis-trans isomerase-like 1 K12733 PPIL1; peptidyl-prolyl cis-trans isomerase-like 1 [EC:5.2.1.8]
D 108565078 peptidyl-prolyl cis-trans isomerase-like 2 K10598 PPIL2; peptidyl-prolyl cis-trans isomerase-like 2 [EC:5.2.1.8]
D 108566028 peptidyl-prolyl cis-trans isomerase-like 3 K12734 PPIL3; peptidyl-prolyl cis-trans isomerase-like 3 [EC:5.2.1.8]
D 108560900 peptidyl-prolyl cis-trans isomerase-like 4 K12735 PPIL4; peptidyl-prolyl cis-trans isomerase-like 4 [EC:5.2.1.8]
D 108561328 peptidylprolyl isomerase domain and WD repeat-containing protein 1 K12736 PPWD1; peptidylprolyl isomerase domain and WD repeat-containing protein 1 [EC:5.2.1.8]
D 108560483 uncharacterized protein LOC108560483 K12737 SDCCAG10; peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8]
D 108560484 peptidyl-prolyl cis-trans isomerase CWC27 homolog K12737 SDCCAG10; peptidyl-prolyl cis-trans isomerase SDCCAG10 [EC:5.2.1.8]
D 108559926 ranBP2-like and GRIP domain-containing protein 4 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
C FKBP
D 108560998 12 kDa FK506-binding protein K09568 FKBP1; FK506-binding protein 1 [EC:5.2.1.8]
D 108566769 peptidyl-prolyl cis-trans isomerase FKBP2 K09569 FKBP2; FK506-binding protein 2 [EC:5.2.1.8]
D 108567266 FK506-binding protein 59 K09571 FKBP4_5; FK506-binding protein 4/5 [EC:5.2.1.8]
D 108557068 inactive peptidyl-prolyl cis-trans isomerase FKBP6 K09572 FKBP6; FK506-binding protein 6 [EC:5.2.1.8]
D 108559436 FK506-binding protein 2 K09577 FKBP14; FK506-binding protein 14 [EC:5.2.1.8]
D 108556545 70 kDa peptidyl-prolyl isomerase-like K20097 FKBPL; FK506-binding protein-like
C Parvulin
D 108560813 putative peptidyl-prolyl cis-trans isomerase dodo isoform X1 K09578 PIN1; peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 [EC:5.2.1.8]
D 108557747 peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 K09579 PIN4; peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 [EC:5.2.1.8]
B Protein disulfide isomerase
C 108560058 thioredoxin, mitochondrial K03671 TXN; thioredoxin
C 108566378 thioredoxin-2 K03671 TXN; thioredoxin
C 108559141 thioredoxin, mitochondrial-like K03671 TXN; thioredoxin
C 108568806 glutaredoxin-C4-like isoform X1 K03676 grxC; glutaredoxin 3
C 108565379 glutaredoxin-related protein 5, mitochondrial K07390 grxD; monothiol glutaredoxin
C 108561362 glutaredoxin domain-containing cysteine-rich protein CG31559-like K17479 GRXCR1; glutaredoxin domain-containing cysteine-rich protein 1
C 108565399 protein disulfide-isomerase K09580 PDIA1; protein disulfide-isomerase A1 [EC:5.3.4.1]
C 108567102 protein disulfide-isomerase A3 K08056 PDIA3; protein disulfide-isomerase A3 [EC:5.3.4.1]
C 108560349 protein disulfide-isomerase A5 K09583 PDIA5; protein disulfide-isomerase A5 [EC:5.3.4.1]
C 108562314 protein disulfide-isomerase A6 K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C 108560883 probable protein disulfide-isomerase A6 K09584 PDIA6; protein disulfide-isomerase A6 [EC:5.3.4.1]
C 108563899 thioredoxin domain-containing protein 5 K13984 TXNDC5; thioredoxin domain-containing protein 5 [EC:5.3.4.1]
C 108563807 protein disulfide-isomerase TMX3 K09585 TMX3; protein disulfide-isomerase [EC:5.3.4.1]
C 108565316 cysteine-rich with EGF-like domain protein 2 isoform X1 K24335 CRELD; protein disulfide-isomerase [EC:5.3.4.1]
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: January 25, 2024