+F Repair protein KO
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DNA Repair and Recombination Proteins - Pseudomonas antarctica
%
!
AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D A7J50_1554 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D A7J50_0754 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
C BER (base exicision repair)
D DNA glycosylases
E A7J50_1579 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E A7J50_5144 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E A7J50_0310 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E A7J50_1157 endonuclease IV K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E A7J50_2797 ATP-dependent DNA helicase K10844 ERCC2; DNA excision repair protein ERCC-2 [EC:5.6.2.3]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D A7J50_2501 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D A7J50_4700 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D A7J50_1119 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D A7J50_5718 Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
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AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D A7J50_1554 cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D A7J50_3032 ADA regulatory protein K10778 ada; AraC family transcriptional regulator, regulatory protein of adaptative response / methylated-DNA-[protein]-cysteine methyltransferase [EC:2.1.1.63]
D A7J50_0754 deoxyribodipyrimidine photo-lyase K01669 phr; deoxyribodipyrimidine photo-lyase [EC:4.1.99.3]
D A7J50_3299 Deoxyribodipyrimidine photolyase K06876 phrB; (6-4)DNA photolyase [EC:4.1.99.13]
D A7J50_3031 Alpha-ketoglutarate-dependent dioxygenase AlkB K03919 alkB; DNA oxidative demethylase [EC:1.14.11.33]
C BER (base exicision repair)
D DNA glycosylases
E A7J50_1579 uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E A7J50_3346 DNA glycosylase K03649 mug; double-stranded uracil-DNA glycosylase [EC:3.2.2.28]
E A7J50_4650 DNA-3-methyladenine glycosylase II K01247 alkA; DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E A7J50_5144 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E A7J50_0310 A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E A7J50_3203 3-methyladenine DNA glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E A7J50_0013 3-methyladenine DNA glycosylase K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E A7J50_5523 Formamidopyrimidine-DNA glycosylase K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E A7J50_1157 endonuclease IV K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E A7J50_5723 exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E A7J50_3542 exonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
D RecJ
E A7J50_4768 Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
D DNA ligase
E A7J50_5437 NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E A7J50_4283 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E A7J50_0082 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E A7J50_2355 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E A7J50_5222 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
E A7J50_3886 UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E A7J50_2210 UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E A7J50_5811 DNA-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E A7J50_0082 DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E A7J50_5437 NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E A7J50_4283 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F A7J50_5257 DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F A7J50_5256 DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F A7J50_5226 DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F A7J50_5728 DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F A7J50_1690 Transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
E A7J50_1162 DNA mismatch repair protein MutS K03555 mutS; DNA mismatch repair protein MutS
D Molecular matchmaker
E A7J50_0505 DNA mismatch repair protein MutL K03572 mutL; DNA mismatch repair protein MutL
D Strand discrimination factor
D DNA exonucleases
E A7J50_4709 exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E A7J50_4816 exodeoxyribonuclease K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E A7J50_5184 Exodeoxyribonuclease 7 small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
E A7J50_1325 Exodeoxyribonuclease X K10857 exoX; exodeoxyribonuclease X [EC:3.1.11.-]
D DNA polymerase III holoenzyme
E A7J50_1422 DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E A7J50_0002 DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E A7J50_1061 DNA polymerase III subunit chi K02339 holC; DNA polymerase III subunit chi [EC:2.7.7.7]
E A7J50_5128 DNA polymerase III subunit delta K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E A7J50_4464 DNA polymerase III subunit delta' K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E A7J50_5357 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E A7J50_5099 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E A7J50_2409 DNA polymerase III subunit epsilon K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
E A7J50_4272 DNA polymerase III subunit gamma/tau K02343 dnaX; DNA polymerase III subunit gamma/tau [EC:2.7.7.7]
D DNA ligase
E A7J50_5437 NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E A7J50_4283 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E A7J50_5811 DNA-dependent helicase K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E A7J50_5220 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E A7J50_1219 restriction endonuclease subunit M K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E A7J50_4417 Putative n6 adenine-specific dna methyltransferase protein K06223 dam; DNA adenine methylase [EC:2.1.1.72]
E A7J50_1754 D12 class N6 adenine-specific DNA methyltransferase K06223 dam; DNA adenine methylase [EC:2.1.1.72]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E A7J50_4960 exodeoxyribonuclease V subunit beta K03582 recB; exodeoxyribonuclease V beta subunit [EC:3.1.11.5]
E A7J50_4961 exodeoxyribonuclease V subunit gamma K03583 recC; exodeoxyribonuclease V gamma subunit [EC:3.1.11.5]
E A7J50_4959 exodeoxyribonuclease V subunit alpha K03581 recD; exodeoxyribonuclease V alpha subunit [EC:3.1.11.5]
E A7J50_1242 Protein RecA K03553 recA; recombination protein RecA
E A7J50_4684 Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E A7J50_4683 Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E A7J50_4685 Crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E A7J50_0392 primosome assembly protein PriA K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E A7J50_4709 exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
E A7J50_3218 chromosome segregation protein SMC K03546 sbcC; DNA repair protein SbcC/Rad50
E A7J50_3217 Putative exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E A7J50_1242 Protein RecA K03553 recA; recombination protein RecA
E A7J50_5060 DNA repair protein RadA K04485 radA; DNA repair protein RadA/Sms
E A7J50_0003 DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E A7J50_5740 ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E A7J50_4768 Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
E A7J50_1069 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E A7J50_4269 Recombination protein RecR K06187 recR; recombination protein RecR
E A7J50_5017 recombinase K03631 recN; DNA repair protein RecN (Recombination protein N)
E A7J50_2016 Recombination-associated protein RdgC K03554 rdgC; recombination associated protein RdgC
E A7J50_4684 Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E A7J50_4683 Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E A7J50_4685 Crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E A7J50_3218 chromosome segregation protein SMC K03546 sbcC; DNA repair protein SbcC/Rad50
E A7J50_3217 Putative exonuclease K03547 sbcD; DNA repair protein SbcD/Mre11
E A7J50_4704 ATP-binding protein K06915 herA; DNA double-strand break repair helicase HerA and related ATPase
E A7J50_5037 DEAD/DEAH box helicase K03726 helS; ATP-dependent DNA helicase [EC:5.6.2.4]
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E A7J50_2742 Non-homologous end joining protein Ku K10979 ku; DNA end-binding protein Ku
E A7J50_2741 Putative ATP-dependent DNA ligase K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F A7J50_1800 DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F A7J50_0004 DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F A7J50_3040 DNA topoisomerase K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
F A7J50_1681 DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F A7J50_5767 Integration host factor K05787 hupA; DNA-binding protein HU-alpha
F A7J50_1057 DNA-binding protein HU K03530 hupB; DNA-binding protein HU-beta
F A7J50_3581 DNA-binding protein HU-beta K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F A7J50_4768 Single-stranded-DNA-specific exonuclease RecJ K07462 recJ; single-stranded-DNA-specific exonuclease [EC:3.1.-.-]
F A7J50_1069 DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F A7J50_4269 Recombination protein RecR K06187 recR; recombination protein RecR
F A7J50_5437 NAD-dependent DNA ligase LigB K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
F A7J50_4283 DNA ligase (NAD(+)) LigA K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
F A7J50_0595 Global DNA-binding transcriptional dual regulator Fis K03557 fis; Fis family transcriptional regulator, factor for inversion stimulation protein
F A7J50_3821 Integration host factor subunit alpha K04764 ihfA; integration host factor subunit alpha
F A7J50_1808 Integration host factor subunit beta K05788 ihfB; integration host factor subunit beta
E Supressor
F A7J50_4709 exonuclease I K01141 sbcB; exodeoxyribonuclease I [EC:3.1.11.1]
F A7J50_0270 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F A7J50_4148 ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F A7J50_2355 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F A7J50_5222 excinuclease ABC subunit A K03701 uvrA; excinuclease ABC subunit A
F A7J50_3886 UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D A7J50_4765 DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D A7J50_5902 Peptidase S24 K03503 umuD; DNA polymerase V [EC:3.4.21.-]
C Other SOS response factors
D A7J50_1242 Protein RecA K03553 recA; recombination protein RecA
D A7J50_2350 LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D A7J50_1685 LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D A7J50_5017 recombinase K03631 recN; DNA repair protein RecN (Recombination protein N)
D A7J50_2079 DNA polymerase II K02336 polB; DNA polymerase II [EC:2.7.7.7]
D A7J50_2351 CDP-6-deoxy-delta-3,4-glucoseen reductase K14160 imuA; protein ImuA
D A7J50_2352 DNA repair nucleotidyltransferase K14161 imuB; protein ImuB
D A7J50_2353 DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D A7J50_5220 Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D A7J50_1243 Regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D A7J50_5692 ATP-dependent DNA helicase Rep K03656 rep; ATP-dependent DNA helicase Rep [EC:5.6.2.4]
D A7J50_1461 ATP-dependent DNA helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D A7J50_1443 DNA ligase-associated DEXH box helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D A7J50_5209 ATP-dependent DNA helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D A7J50_2501 NUDIX hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D A7J50_4700 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D A7J50_1119 DNA mismatch repair protein MutT K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D A7J50_5718 Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D A7J50_4491 Ribonucleoside-diphosphate reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D A7J50_2663 Ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024