+E Replication protein KO
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DNA Replication Proteins - Penicillium rubens
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
D N7525_011004 ATPase AAA-type core K02603 ORC1; origin recognition complex subunit 1
D N7525_004792 uncharacterized protein K02604 ORC2; origin recognition complex subunit 2
D N7525_007693 uncharacterized protein K02605 ORC3; origin recognition complex subunit 3
D N7525_010004 uncharacterized protein K02606 ORC4; origin recognition complex subunit 4
D N7525_004203 uncharacterized protein K02607 ORC5; origin recognition complex subunit 5
D N7525_006526 uncharacterized protein K02608 ORC6; origin recognition complex subunit 6
D N7525_006920 uncharacterized protein K02213 CDC6; cell division control protein 6
D N7525_002497 uncharacterized protein K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
D N7525_010911 uncharacterized protein K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D N7525_010706 uncharacterized protein K02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]
D N7525_008100 uncharacterized protein K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
D N7525_007653 uncharacterized protein K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
D N7525_004344 DNA replication licensing factor MCM7 K02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]
C CDK (cyclin dependent kinase)
C DDK (Dbf-4 dependent kinase)
D N7525_009249 uncharacterized protein K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
D N7525_001753 uncharacterized protein K02309 DBF4; regulatory subunit for Cdc7p protein kinase
C GINS complex
D N7525_005674 uncharacterized protein K10732 GINS1; GINS complex subunit 1
D N7525_010012 uncharacterized protein K10733 GINS2; GINS complex subunit 2
D N7525_005265 uncharacterized protein K10735 GINS4; GINS complex subunit 4
C Other initiation factors
D N7525_006855 uncharacterized protein K03507 DPB11; DNA replication regulator DPB11
D N7525_010273 uncharacterized protein K06628 CDC45; cell division control protein 45
D N7525_003164 uncharacterized protein K10736 MCM10; minichromosome maintenance protein 10
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
D N7525_004270 uncharacterized protein K02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
D N7525_007269 uncharacterized protein K02321 POLA2; DNA polymerase alpha subunit B
D N7525_008847 uncharacterized protein K02684 PRI1; DNA primase small subunit [EC:2.7.7.102]
D N7525_003829 uncharacterized protein K02685 PRI2; DNA primase large subunit
C DNA polymerase epsilon complex
D N7525_001018 uncharacterized protein K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
D N7525_007712 uncharacterized protein K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
C DNA polymerase delta complex
D N7525_006644 uncharacterized protein K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
D N7525_003427 uncharacterized protein K02328 POLD2; DNA polymerase delta subunit 2
D N7525_006640 uncharacterized protein K03504 POLD3; DNA polymerase delta subunit 3
D N7525_006515 uncharacterized protein K03505 POLD4; DNA polymerase delta subunit 4
C DNA polymerase gamma complex (mitochondrial)
D N7525_006907 uncharacterized protein K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
C RPA (replication protein A)
D N7525_007725 uncharacterized protein K07466 RFA1; replication factor A1
D N7525_006375 uncharacterized protein K10739 RFA2; replication factor A2
C RFC (replication factor C)
D N7525_009831 uncharacterized protein K10754 RFC1; replication factor C subunit 1
D N7525_002069 uncharacterized protein K10755 RFC2_4; replication factor C subunit 2/4
D N7525_009151 uncharacterized protein K10755 RFC2_4; replication factor C subunit 2/4
D N7525_007989 uncharacterized protein K10756 RFC3_5; replication factor C subunit 3/5
D N7525_009834 uncharacterized protein K10756 RFC3_5; replication factor C subunit 3/5
C RNase H
D N7525_006955 uncharacterized protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D N7525_005179 uncharacterized protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D N7525_011266 uncharacterized protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D N7525_002019 uncharacterized protein K10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
D N7525_005372 uncharacterized protein K10745 RNASEH2C; ribonuclease H2 subunit C
C Other elongation factors
D N7525_010779 uncharacterized protein K04802 PCNA; proliferating cell nuclear antigen
D N7525_005685 uncharacterized protein K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D N7525_010032 uncharacterized protein K19783 HCS1; DNA polymerase alpha-associated DNA helicase A [EC:5.6.2.3]
D N7525_009220 uncharacterized protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D N7525_008850 XPG/RAD2 endonuclease K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
D N7525_003794 uncharacterized protein K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
D N7525_006546 uncharacterized protein K26118 ATAD5; ATPase family AAA domain-containing protein 5
B DNA Replication Termination Factors
C DNA methylation enzymes
D N7525_009713 uncharacterized protein K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
C Prevention of re-replication factors
C Telomere proteins
D Shelterin complex
E N7525_006712 uncharacterized protein K11109 POT1; protection of telomeres protein 1
D TERB1-TERB2-MAJIN complex
D CST complex (animals)
D CST complex (yeast)
D RIF proteins
D SIR proteins
E N7525_000026 uncharacterized protein K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
E N7525_011039 uncharacterized protein K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
E N7525_005695 uncharacterized protein K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
E N7525_005392 uncharacterized protein K11121 SIR2; NAD-dependent protein deacetylase SIR2 [EC:2.3.1.286]
C Telomerase complex (animals)
D Dyskerin complex
E N7525_005835 Translation elongation/initiation factor/Ribosomal beta-barrel K11128 GAR1; H/ACA ribonucleoprotein complex subunit 1
E N7525_002913 uncharacterized protein K11129 NHP2; H/ACA ribonucleoprotein complex subunit 2
E N7525_008535 uncharacterized protein K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
C Telomerase complex (fungi)
D Sm core complex
E N7525_003451 uncharacterized protein K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E N7525_001522 uncharacterized protein K11087 SNRPD1; small nuclear ribonucleoprotein D1
E N7525_007458 Ribonucleoprotein LSM domain eukaryotic/archaea-type K11096 SNRPD2; small nuclear ribonucleoprotein D2
E N7525_005085 Small nuclear ribonucleoprotein SmD3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E N7525_008588 Ribonucleoprotein LSM domain eukaryotic/archaea-type K11097 SNRPE; small nuclear ribonucleoprotein E
E N7525_006810 uncharacterized protein K11098 SNRPF; small nuclear ribonucleoprotein F
E N7525_009439 uncharacterized protein K11099 SNRPG; small nuclear ribonucleoprotein G
C ELG1-RFC complex
D N7525_002069 uncharacterized protein K10755 RFC2_4; replication factor C subunit 2/4
D N7525_009151 uncharacterized protein K10755 RFC2_4; replication factor C subunit 2/4
D N7525_007989 uncharacterized protein K10756 RFC3_5; replication factor C subunit 3/5
D N7525_009834 uncharacterized protein K10756 RFC3_5; replication factor C subunit 3/5
C MRN complex
D N7525_006340 uncharacterized protein K10865 MRE11; double-strand break repair protein MRE11
D N7525_005948 uncharacterized protein K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
C Other termination factors
D N7525_007493 uncharacterized protein K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D N7525_001539 uncharacterized protein K10901 BLM; bloom syndrome protein [EC:5.6.2.4]
D N7525_004004 uncharacterized protein K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D N7525_002196 uncharacterized protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D N7525_008322 uncharacterized protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D N7525_009301 uncharacterized protein K11135 PINX1; Pin2-interacting protein X1
D N7525_001362 uncharacterized protein K11137 TELO2; telomere length regulation protein
D N7525_006856 uncharacterized protein K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D N7525_006490 uncharacterized protein K23314 WRAP53; telomerase Cajal body protein 1
D N7525_005953 uncharacterized protein K25059 SDE2; replication stress response regulator SDE2
D N7525_006952 uncharacterized protein K25186 RTF2; replication termination factor 2
D N7525_007106 uncharacterized protein K22485 TBF1; protein TBF1
B DNA Topoisomerases
C N7525_003823 uncharacterized protein K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C N7525_006111 DNA topoisomerase II top2-Penicillium chrysogenum K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C N7525_000471 uncharacterized protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
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AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
D RNase H
E N7525_006955 uncharacterized protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E N7525_005179 uncharacterized protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E N7525_011266 uncharacterized protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D Other elongation factors
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E N7525_006955 uncharacterized protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E N7525_005179 uncharacterized protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
E N7525_011266 uncharacterized protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
E N7525_005685 uncharacterized protein K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
E N7525_009220 uncharacterized protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E N7525_003794 uncharacterized protein K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
C Prevention of re-replication factors
B DNA Topoisomerases
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022