+E Messenger RNA Biogenesis KO
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Messenger RNA Biogenesis - Pan troglodytes (chimpanzee)
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AEukaryotic type
B mRNA processing factors
C 5' end processing
D Capping factors
E 455501 RNMT; mRNA cap guanine-N7 methyltransferase isoform X2 K00565 RNMT; mRNA (guanine-N7-)-methyltransferase [EC:2.1.1.56]
E 462878 RNGTT; mRNA-capping enzyme isoform X2 K13917 RNGTT; mRNA-capping enzyme [EC:2.7.7.50 3.6.1.74]
E 462378 CDK7; cyclin-dependent kinase 7 isoform X1 K02202 CDK7; cyclin-dependent kinase 7 [EC:2.7.11.22 2.7.11.23]
E 471998 CMTR1; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 isoform X2 K14589 CMTR1; cap1 methyltransferase [EC:2.1.1.57]
E 745202 CMTR2; cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 K14590 CMTR2; cap2 methyltransferase [EC:2.1.1.296]
E 453598 FAM103A1; RNMT-activating mini protein K18708 FAM103A1; RNMT-activating mini protein
D Cap binding complex
E 464601 NCBP1; nuclear cap-binding protein subunit 1 isoform X1 K12882 NCBP1; nuclear cap-binding protein subunit 1
E 460966 NCBP2; nuclear cap-binding protein subunit 2 isoform X1 K12883 NCBP2; nuclear cap-binding protein subunit 2
E 112206919 nuclear cap-binding protein subunit 2-like K12883 NCBP2; nuclear cap-binding protein subunit 2
C 3' end processing
D Pre-mRNA cleavage factor Im (CFIm)
E 454100 NUDT21; cleavage and polyadenylation specificity factor subunit 5 K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 100615531 LOW QUALITY PROTEIN: cleavage and polyadenylation specificity factor subunit 5-like K14397 NUDT21; cleavage and polyadenylation specificity factor subunit 5
E 452068 CPSF6; cleavage and polyadenylation specificity factor subunit 6 isoform X4 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
E 451237 CPSF7; cleavage and polyadenylation specificity factor subunit 7 isoform X4 K14398 CPSF6_7; cleavage and polyadenylation specificity factor subunit 6/7
D Pre-mRNA cleavage factor IIm (CFIIm)
E 451198 CLP1; polyribonucleotide 5'-hydroxyl-kinase Clp1 K14399 CLP1; polyribonucleotide 5'-hydroxyl-kinase [EC:2.7.1.78]
E 451458 PCF11; pre-mRNA cleavage complex 2 protein Pcf11 isoform X1 K14400 PCF11; pre-mRNA cleavage complex 2 protein Pcf11
D Cleavage and polyadenylation specificity factor (CPSF) complex
E 738846 CPSF2; cleavage and polyadenylation specificity factor subunit 2 isoform X1 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 459017 CPSF3; cleavage and polyadenylation specificity factor subunit 3 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 463572 CPSF4; cleavage and polyadenylation specificity factor subunit 4 isoform X2 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 744631 CPSF4L; putative cleavage and polyadenylation specificity factor subunit 4-like protein isoform X2 K14404 CPSF4; cleavage and polyadenylation specificity factor subunit 4
E 107974320 FIP1L1; pre-mRNA 3'-end-processing factor FIP1 isoform X1 K14405 FIP1L1; pre-mRNA 3'-end-processing factor FIP1
E 470527 WDR33; pre-mRNA 3' end processing protein WDR33 isoform X1 K15542 PFS2; polyadenylation factor subunit 2
E 460419 WDR82; WD repeat-containing protein 82 K14962 WDR82; COMPASS component SWD2
E 462795 PPP1CC; serine/threonine-protein phosphatase PP1-gamma catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 745709 PPP1CA; serine/threonine-protein phosphatase PP1-alpha catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 743656 serine/threonine-protein phosphatase PP1-gamma catalytic subunit K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 459118 PPP1CB; serine/threonine-protein phosphatase PP1-beta catalytic subunit isoform X1 K06269 PPP1C; serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
E 742879 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
E 472500 RNA polymerase II subunit A C-terminal domain phosphatase SSU72 K15544 SSU72; RNA polymerase II subunit A C-terminal domain phosphatase SSU72 [EC:3.1.3.16]
D Cleavage stimulation factor (CSTF) complex
E 100610308 CSTF1; cleavage stimulation factor subunit 1 K14406 CSTF1; cleavage stimulation factor subunit 1
E 473699 CSTF2; cleavage stimulation factor subunit 2 isoform X3 K14407 CSTF2; cleavage stimulation factor subunit 2
E 450463 CSTF2T; cleavage stimulation factor subunit 2 tau variant K14407 CSTF2; cleavage stimulation factor subunit 2
E 451108 CSTF3; cleavage stimulation factor subunit 3 K14408 CSTF3; cleavage stimulation factor subunit 3
E 456142 SYMPK; symplekin K06100 SYMPK; symplekin
D U7-dependent histone pre-mRNA processing factors
E 470014 SNRPB; small nuclear ribonucleoprotein-associated proteins B and B' K11086 SNRPB; small nuclear ribonucleoprotein B and B'
E 100611816 SNRPD3; small nuclear ribonucleoprotein Sm D3 K11088 SNRPD3; small nuclear ribonucleoprotein D3
E 741566 SNRPE; small nuclear ribonucleoprotein E isoform X3 K11097 SNRPE; small nuclear ribonucleoprotein E
E 107968725 small nuclear ribonucleoprotein E-like K11097 SNRPE; small nuclear ribonucleoprotein E
E 452143 SNRPF; small nuclear ribonucleoprotein F K11098 SNRPF; small nuclear ribonucleoprotein F
E 736959 SNRPG; small nuclear ribonucleoprotein G isoform X1 K11099 SNRPG; small nuclear ribonucleoprotein G
E 107969678 putative small nuclear ribonucleoprotein G-like protein 15 K11099 SNRPG; small nuclear ribonucleoprotein G
E 456754 LSM10; U7 snRNA-associated Sm-like protein LSm10 K25591 LSM10; U7 snRNA-associated Sm-like protein LSm10
E 736032 LSM11; U7 snRNA-associated Sm-like protein LSm11 K25592 LSM11; U7 snRNA-associated Sm-like protein LSm11
E 738846 CPSF2; cleavage and polyadenylation specificity factor subunit 2 isoform X1 K14402 CPSF2; cleavage and polyadenylation specificity factor subunit 2
E 459017 CPSF3; cleavage and polyadenylation specificity factor subunit 3 K14403 CPSF3; cleavage and polyadenylation specificity factor subunit 3 [EC:3.1.27.-]
E 473699 CSTF2; cleavage stimulation factor subunit 2 isoform X3 K14407 CSTF2; cleavage stimulation factor subunit 2
E 450463 CSTF2T; cleavage stimulation factor subunit 2 tau variant K14407 CSTF2; cleavage stimulation factor subunit 2
E 456142 SYMPK; symplekin K06100 SYMPK; symplekin
E 471120 SLBP; histone RNA hairpin-binding protein K18710 SLBP; histone RNA hairpin-binding protein
E 472070 CASP8AP2; CASP8-associated protein 2 isoform X2 K25593 CASP8AP2; CASP8-associated protein 2
D DRB sensitivity inducing factor (DSIF) complex
E 468422 SUPT4H1; transcription elongation factor SPT4 K15171 SUPT4H1; transcription elongation factor SPT4
E 456024 SUPT5H; transcription elongation factor SPT5 isoform X1 K15172 SUPT5H; transcription elongation factor SPT5
D N6-methyltransferase complex
E 452765 METTL3; N6-adenosine-methyltransferase catalytic subunit K05925 METTL3; mRNA m6A methyltransferase catalytic subunit [EC:2.1.1.348]
E 461454 METTL14; N6-adenosine-methyltransferase non-catalytic subunit K23960 METTL14; mRNA m6A methyltransferase non-catalytic subunit
E 468487 METTL4; methyltransferase-like protein 4 isoform X3 K24174 METTL4; N(6)-adenine-specific DNA methyltransferase [EC:2.1.1.72]
E 468142 METTL16; U6 small nuclear RNA (adenine-(43)-N(6))-methyltransferase K11393 METTL16; U6 snRNA m6A methyltransferase [EC:2.1.1.346]
E 463110 WTAP; pre-mRNA-splicing regulator WTAP isoform X4 K22824 WTAP; pre-mRNA-splicing regulator WTAP
E 464288 VIRMA; protein virilizer homolog isoform X2 K22910 VIRMA; protein virilizer
E 460403 RBM15B; putative RNA-binding protein 15B K13190 RBM15; RNA-binding protein 15
E 469415 RBM15; putative RNA-binding protein 15 isoform X1 K13190 RBM15; RNA-binding protein 15
E 452581 ZC3H13; zinc finger CCCH domain-containing protein 13 isoform X1 K22909 ZC3H13; zinc finger CCCH domain-containing protein 13
E 472482 CBLL1; E3 ubiquitin-protein ligase Hakai isoform X3 K15685 CBLL1; E3 ubiquitin-protein ligase Hakai [EC:2.3.2.27]
D Poly(A) addition factors
E 459259 PAPOLG; poly(A) polymerase gamma isoform X3 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 100610673 PAPOLB; poly(A) polymerase beta K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 100614622 PAPOLA; poly(A) polymerase alpha isoform X1 K14376 PAP; poly(A) polymerase [EC:2.7.7.19]
E 461783 PAPD4; poly(A) RNA polymerase GLD2 isoform X1 K14079 PAPD4; poly(A) RNA polymerase GLD2 [EC:2.7.7.19]
E 451254 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase K18709 TUT1; speckle targeted PIP5K1A-regulated poly(A) polymerase [EC:2.7.7.19 2.7.7.52]
D Negative regulators of mRNA 3' end processing
E 470638 BARD1; BRCA1-associated RING domain protein 1 isoform X2 K10683 BARD1; BRCA1-associated RING domain protein 1
E 452615 RBM26; RNA-binding protein 26 isoform X1 K13192 RBM26; RNA-binding protein 26
E 454090 FTO; alpha-ketoglutarate-dependent dioxygenase FTO isoform X4 K19469 FTO; mRNA N6-methyladenine demethylase [EC:1.14.11.53]
E 107974879 TARDBP; TAR DNA-binding protein 43 K23600 TARDBP; TAR DNA-binding protein 43
C Other processing factors
D 454809 DHX40; probable ATP-dependent RNA helicase DHX40 isoform X1 K18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]
D 107969000 probable ATP-dependent RNA helicase DHX40 K18711 DHX40; ATP-dependent RNA helicase DHX40 [EC:5.6.2.6]
D 450293 KIN; DNA/RNA-binding protein KIN17 isoform X2 K13102 KIN; DNA/RNA-binding protein KIN17
D 459730 METTL8; methyltransferase-like protein 8 isoform X1 K24975 METTL8; mRNA N(3)-methylcytidine methyltransferase METTL8 [EC:2.1.1.-]
D 453901 METTL22; methyltransferase-like protein 22 isoform X4 K23040 METTL22; methyltransferase-like protein 22 [EC:2.1.1.-]
D 456668 FAM46B; putative nucleotidyltransferase FAM46B K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 462847 FAM46A; putative nucleotidyltransferase FAM46A isoform X3 K23033 TENT5A_B; terminal nucleotidyltransferase 5A/B [EC:2.7.7.-]
D 469434 TENT5C; terminal nucleotidyltransferase 5C K23034 TENT5C; terminal nucleotidyltransferase 5C [EC:2.7.7.19]
D 740850 FAM46D; putative nucleotidyltransferase FAM46D K23035 TENT5D; terminal nucleotidyltransferase 5D [EC:2.7.7.19]
D 453092 ZC3H14; zinc finger CCCH domain-containing protein 14 isoform X1 K23038 ZC3H14; zinc finger CCCH domain-containing protein 14
D 463860 SRRT; serrate RNA effector molecule homolog isoform X4 K27103 SRRT; serrate RNA effector molecule
B mRNA surveillance and transport factors
C Transport factors
D EJC complex
E 457983 RBM8A; RNA-binding protein 8A isoform X1 K12876 RBM8A; RNA-binding protein 8A
E 736868 protein mago nashi homolog K12877 MAGOH; protein mago nashi
E 100613301 MAGOHB; protein mago nashi homolog 2 isoform X2 K12877 MAGOH; protein mago nashi
E 104001049 MAGOH; protein mago nashi homolog K12877 MAGOH; protein mago nashi
E 744649 ALYREF; THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 463180 DDX39B; spliceosome RNA helicase DDX39B K12812 DDX39B; ATP-dependent RNA helicase UAP56/SUB2 [EC:5.6.2.7]
E 454941 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 742589 eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 470757 CCDC174; coiled-coil domain-containing protein 174 K25178 CCDC174; coiled-coil domain-containing protein 174
E 454646 CASC3; protein CASC3 isoform X1 K14323 CASC3; protein CASC3
E 452467 SAP18; histone deacetylase complex subunit SAP18 K14324 SAP18; histone deacetylase complex subunit SAP18
E 452875 PNN; pinin isoform X1 K13114 PNN; pinin
E 452792 ACIN1; apoptotic chromatin condensation inducer in the nucleus isoform X7 K12875 ACIN1; apoptotic chromatin condensation inducer in the nucleus
E 750086 RNPS1; RNA-binding protein with serine-rich domain 1 K14325 RNPS1; RNA-binding protein with serine-rich domain 1
E 456632 SRRM1; serine/arginine repetitive matrix protein 1 isoform X11 K13171 SRRM1; serine/arginine repetitive matrix protein 1
D TREX complex
E 455324 THOC1; THO complex subunit 1 isoform X1 K12878 THOC1; THO complex subunit 1
E 465844 THOC2; THO complex subunit 2 isoform X1 K12879 THOC2; THO complex subunit 2
E 462282 THOC3; THO complex subunit 3 K12880 THOC3; THO complex subunit 3
E 744649 ALYREF; THO complex subunit 4 K12881 THOC4; THO complex subunit 4
E 458742 THOC5; THO complex subunit 5 homolog K13174 THOC5; THO complex subunit 5
E 107968770 THOC6; THO complex subunit 6 homolog isoform X1 K13175 THOC6; THO complex subunit 6
E 473334 THOC7; THO complex subunit 7 homolog isoform X1 K13176 THOC7; THO complex subunit 7
D TREX-2 complex
E 452692 PCID2; PCI domain-containing protein 2 K23801 PCID2; nuclear mRNA export protein PCID2/THP1
E 747549 SEM1; 26S proteasome complex subunit SEM1 K10881 SHFM1; 26 proteasome complex subunit DSS1
E 735847 ENY2; transcription and mRNA export factor ENY2 isoform X2 K11368 ENY2; enhancer of yellow 2 transcription factor
E 107971232 CETN2; centrin-2 K10840 CETN2; centrin-2
E 738363 CETN3; centrin-3 isoform X1 K16466 CETN3; centrin-3
E 470113 MCM3AP; germinal-center associated nuclear protein isoform X1 K24317 MCM3AP; germinal-center associated nuclear protein [EC:2.3.1.48]
D Nuclear pore complex
E 457588 TPR; nucleoprotein TPR isoform X2 K09291 TPR; nucleoprotein TPR
E 469982 RAE1; mRNA export factor K14298 RAE1; mRNA export factor
E 460167 SEC13; protein SEC13 homolog K14004 SEC13; protein transport protein SEC13
E 452180 NUP37; nucleoporin Nup37 K14302 NUP37; nuclear pore complex protein Nup37
E 107966223 NUP85; nuclear pore complex protein Nup85 isoform X1 K14304 NUP85; nuclear pore complex protein Nup85
E 472151 NUP43; nucleoporin Nup43 isoform X1 K14305 NUP43; nuclear pore complex protein Nup43
E 461955 NUP50; nuclear pore complex protein Nup50 K14295 NUP50; nuclear pore complex protein Nup50
E 461240 NUP54; nucleoporin p54 isoform X1 K14308 NUP54; nuclear pore complex protein Nup54
E 100614218 NUP62; nuclear pore glycoprotein p62 K14306 NUP62; nuclear pore complex protein Nup62
E 748596 NUP88; nuclear pore complex protein Nup88 K14318 NUP88; nuclear pore complex protein Nup88
E 454107 NUP93; nuclear pore complex protein Nup93 isoform X2 K14309 NUP93; nuclear pore complex protein Nup93
E 450971 NUP98; nuclear pore complex protein Nup98-Nup96 isoform X6 K14297 NUP98; nuclear pore complex protein Nup98-Nup96
E 467062 NUP107; nuclear pore complex protein Nup107 isoform X1 K14301 NUP107; nuclear pore complex protein Nup107
E 457804 NUP133; nuclear pore complex protein Nup133 K14300 NUP133; nuclear pore complex protein Nup133
E 464912 NUP188; nucleoporin NUP188 homolog isoform X2 K14311 NUP188; nuclear pore complex protein Nup188
E 462455 NUP153; nuclear pore complex protein Nup153 isoform X2 K14296 NUP153; nuclear pore complex protein Nup153
E 461913 NUP155; nuclear pore complex protein Nup155 isoform X1 K14312 NUP155; nuclear pore complex protein Nup155
E 451179 NUP160; nuclear pore complex protein Nup160 isoform X1 K14303 NUP160; nuclear pore complex protein Nup160
E 459802 NUP35; nucleoporin NUP53 isoform X1 K14313 NUP35; nuclear pore complex protein Nup53
E 472524 NUP205; nuclear pore complex protein Nup205 isoform X2 K14310 NUP205; nuclear pore complex protein Nup205
E 457345 NUP210L; nuclear pore membrane glycoprotein 210-like isoform X3 K14314 NUP210; nuclear pore complex protein Nup210
E 460189 NUP210; nuclear pore membrane glycoprotein 210 isoform X1 K14314 NUP210; nuclear pore complex protein Nup210
E 464807 NUP214; nuclear pore complex protein Nup214 isoform X1 K14317 NUP214; nuclear pore complex protein Nup214
E 741888 POM121; nuclear envelope pore membrane protein POM 121 isoform X2 K14316 POM121; nuclear pore complex protein Nup121
E 462503 POM121L2; POM121-like protein 2 K14316 POM121; nuclear pore complex protein Nup121
E 745060 POM121C; nuclear envelope pore membrane protein POM 121C isoform X1 K14316 POM121; nuclear pore complex protein Nup121
E 452497 NUP58; nucleoporin p58/p45 isoform X2 K14307 NUPL1; nucleoporin p58/p45
E 472312 NUPL2; nucleoporin-like protein 2 isoform X1 K14321 NUPL2; nucleoporin-like protein 2
E 456867 NDC1; nucleoporin NDC1 isoform X4 K14315 NDC1; nucleoporin NDC1
E 100613956 SEH1L; nucleoporin SEH1 isoform X4 K14299 SEH1; nucleoporin SEH1
E 749348 RANBP2; LOW QUALITY PROTEIN: E3 SUMO-protein ligase RanBP2 K12172 RANBP2; E3 SUMO-protein ligase RanBP2 [EC:2.3.2.-]
E 460902 SENP2; sentrin-specific protease 2 isoform X3 K03345 SENP2; sentrin-specific protease 2 (axin associating molecule) [EC:3.4.22.68]
E 467003 AAAS; aladin K14320 AAAS; aladin
E 738363 CETN3; centrin-3 isoform X1 K16466 CETN3; centrin-3
E 464770 GLE1; nucleoporin GLE1 isoform X1 K18723 GLE1; nucleoporin GLE1
E 451267 NXF1; nuclear RNA export factor 1 K14284 NXF; nuclear RNA export factor
E 735423 nuclear RNA export factor 2 K14284 NXF; nuclear RNA export factor
E 465774 NXF3; nuclear RNA export factor 3 K14284 NXF; nuclear RNA export factor
E 100610724 NXF5; nuclear RNA export factor 5 K14284 NXF; nuclear RNA export factor
E 100611904 LOW QUALITY PROTEIN: nuclear RNA export factor 2-like K14284 NXF; nuclear RNA export factor
E 458138 NXT1; NTF2-related export protein 1 K14285 NXT1_2; NTF2-related export protein 1/2
E 473728 NXT2; NTF2-related export protein 2 isoform X1 K14285 NXT1_2; NTF2-related export protein 1/2
E 749583 NTF2-related export protein 1-like K14285 NXT1_2; NTF2-related export protein 1/2
E 467629 NPAP1; nuclear pore-associated protein 1 K26564 NPAP1; nuclear pore-associated protein 1
D Ran-mediated transport factors
E 452414 RAN; GTP-binding nuclear protein Ran isoform X1 K07936 RAN; GTP-binding nuclear protein Ran
E 748502 ANP32A; acidic leucine-rich nuclear phosphoprotein 32 family member A isoform X1 K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 461587 ANP32C; acidic leucine-rich nuclear phosphoprotein 32 family member C K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 100614293 ANP32D; LOW QUALITY PROTEIN: acidic leucine-rich nuclear phosphoprotein 32 family member D K18646 ANP32A_C_D; acidic leucine-rich nuclear phosphoprotein 32 family member A/C/D
E 464605 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B isoform X1 K18647 ANP32B; acidic leucine-rich nuclear phosphoprotein 32 family member B
E 100551504 TNFSF13; tumor necrosis factor ligand superfamily member 13 K05475 TNFSF13; tumor necrosis factor ligand superfamily member 13
E 743010 ELAVL1; ELAV-like protein 1 K13088 ELAVL1; ELAV-like protein 1
E 465023 ELAVL2; ELAV-like protein 2 isoform X11 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 735317 ELAVL4; ELAV-like protein 4 isoform X8 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 746159 ELAVL3; ELAV-like protein 3 isoform X1 K13208 ELAVL2_3_4; ELAV like protein 2/3/4
E 462289 FAF2; FAS-associated factor 2 isoform X4 K18726 FAF2; FAS-associated factor 2
E 747490 VCP; transitional endoplasmic reticulum ATPase K13525 VCP; transitional endoplasmic reticulum ATPase
E 452896 VCPKMT; protein-lysine methyltransferase METTL21D isoform X1 K21806 VCPKMT; protein N-lysine methyltransferase METTL21D [EC:2.1.1.-]
E 455748 TNPO2; transportin-2 isoform X4 K18727 TNPO2; transportin-2
E 459534 XPO1; exportin-1 isoform X1 K14290 XPO1; exportin-1
E 464037 XPO7; exportin-7 isoform X2 K18460 XPO7; exportin-7
E 739299 RANBP17; ran-binding protein 17 isoform X5 K24115 RANBP17; Ran-binding protein 17
E 458980 RANGAP1; ran GTPase-activating protein 1 isoform X5 K14319 RANGAP1; Ran GTPase-activating protein 1
E 454590 TAF15; TATA-binding protein-associated factor 2N isoform X1 K14651 TAF15; transcription initiation factor TFIID subunit 15
D eIF4F and regulatory proteins
E 460015 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X2 K03259 EIF4E; translation initiation factor 4E
E 462294 EIF4E1B; eukaryotic translation initiation factor 4E type 1B isoform X1 K03259 EIF4E; translation initiation factor 4E
E 461391 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 460917 EIF4A2; eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E 748995 EIF4A1; eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E 460888 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X11 K03260 EIF4G; translation initiation factor 4G
E 466443 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 469204 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 737509 EIF4B; eukaryotic translation initiation factor 4B isoform X2 K03258 EIF4B; translation initiation factor 4B
E 472414 EIF4H; eukaryotic translation initiation factor 4H isoform X1 K24086 EIF4H; translation initiation factor 4H
E 464114 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1 K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1
E 100610028 EIF4EBP2; eukaryotic translation initiation factor 4E-binding protein 2 K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2
E 100533103 EIF4EBP3; eukaryotic translation initiation factor 4E-binding protein 3 K18645 EIF4EBP3; eukaryotic translation initiation factor 4E binding protein 3
E 107970226 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X6 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 457726 ANGEL2; protein angel homolog 2 isoform X4 K18729 ANGEL; protein angel
E 453059 ANGEL1; protein angel homolog 1 isoform X2 K18729 ANGEL; protein angel
E 465894 FMR1; synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 746398 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X7 K15516 FMR; fragile X mental retardation protein
E 749002 FXR2; fragile X mental retardation syndrome-related protein 2 isoform X1 K15516 FMR; fragile X mental retardation protein
E 462221 CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 453278 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X4 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 471715 GEMIN5; gem-associated protein 5 isoform X1 K13133 GEMIN5; gem associated protein 5
E 461066 TACC3; transforming acidic coiled-coil-containing protein 3 isoform X1 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 467743 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 461123 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 462277 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 739487 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 742915 DDX3X; ATP-dependent RNA helicase DDX3X isoform X1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 460017 GIGYF2; GRB10-interacting GYF protein 2 isoform X4 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 472671 GIGYF1; GRB10-interacting GYF protein 1 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 465742 PABPC5; polyadenylate-binding protein 5 K13126 PABPC; polyadenylate-binding protein
E 458273 PABPC1L; polyadenylate-binding protein 1-like isoform X3 K13126 PABPC; polyadenylate-binding protein
E 452494 PABPC3; polyadenylate-binding protein 3 K13126 PABPC; polyadenylate-binding protein
E 471308 PABPC4L; polyadenylate-binding protein 4-like isoform X1 K13126 PABPC; polyadenylate-binding protein
E 456782 PABPC4; polyadenylate-binding protein 4 isoform X2 K13126 PABPC; polyadenylate-binding protein
E 464318 PABPC1; polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 100615000 polyadenylate-binding protein 1-like 2 K13126 PABPC; polyadenylate-binding protein
E 112204072 PABPC1L2A; polyadenylate-binding protein 1-like 2 K13126 PABPC; polyadenylate-binding protein
E 100614277 PAIP1; polyadenylate-binding protein-interacting protein 1 isoform X1 K14322 PAIP1; polyadenylate-binding protein-interacting protein 1
E 462103 PAIP2; polyadenylate-binding protein-interacting protein 2 K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 738296 PAIP2B; polyadenylate-binding protein-interacting protein 2B K27470 PAIP2; polyadenylate-binding protein-interacting protein 2
E 462573 SKIV2L; helicase SKI2W isoform X1 K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 373853 DEAF1; deformed epidermal autoregulatory factor 1 homolog K23041 DEAF1; deformed epidermal autoregulatory factor 1
E 465836 MCTS1; malignant T-cell-amplified sequence 1 isoform X2 K07575 MCTS; malignant T-cell-amplified sequence
E 745307 DENR; density-regulated protein K24272 DENR; density-regulated protein
D APOBEC1-ACF complex
E 748253 APOBEC1; C->U-editing enzyme APOBEC-1 isoform X1 K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 466076 A1CF; APOBEC1 complementation factor isoform X1 K24978 A1CF; APOBEC1 complementation factor
D Other transport factors
E 451975 PYM1; partner of Y14 and mago isoform X1 K14294 WIBG; partner of Y14 and mago
E 470592 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 739306 HNRPA1LK1; heterogeneous nuclear ribonucleoprotein A1-like 1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 464260 heterogeneous nuclear ribonucleoprotein A1-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 747284 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 746306 heterogeneous nuclear ribonucleoprotein A1-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 737627 heterogeneous nuclear ribonucleoprotein A1-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 101059544 heterogeneous nuclear ribonucleoprotein A1-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 104001099 HNRNPA1L2; LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein A1-like 2 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 107973587 heterogeneous nuclear ribonucleoprotein A3-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 455549 DAZAP1; DAZ-associated protein 1 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 748578 MSI2; RNA-binding protein Musashi homolog 2 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 452305 MSI1; RNA-binding protein Musashi homolog 1 isoform X1 K14411 MSI; RNA-binding protein Musashi
E 463015 HBS1L; HBS1-like protein isoform X1 K14416 HBS1; elongation factor 1 alpha-like protein
E 104001088 PELO; protein pelota homolog K06965 PELO; protein pelota
E 452797 polyadenylate-binding protein 2 isoform X1 K14396 PABPN1; polyadenylate-binding protein 2
E 100612015 PABPN1L; embryonic polyadenylate-binding protein 2 isoform X1 K14396 PABPN1; polyadenylate-binding protein 2
E 454213 DDX19B; ATP-dependent RNA helicase DDX19B K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 107966214 DDX19A; ATP-dependent RNA helicase DDX19A isoform X1 K18655 DDX19; ATP-dependent RNA helicase DDX19/DBP5 [EC:5.6.2.7]
E 451649 DDX25; ATP-dependent RNA helicase DDX25 K18656 DDX25; ATP-dependent RNA helicase DDX25 [EC:5.6.2.7]
E 468695 XAB2; pre-mRNA-splicing factor SYF1 K12867 SYF1; pre-mRNA-splicing factor SYF1
E 100568439 RCC1; regulator of chromosome condensation K11493 RCC1; regulator of chromosome condensation
E 453549 LARP6; la-related protein 6 K18733 LARP6; la-related protein 6
E 471649 PURA; transcriptional activator protein Pur-alpha isoform X1 K21772 PURA; transcriptional activator protein Pur-alpha
E 472357 PURB; transcriptional activator protein Pur-beta K21799 PURB; transcriptional activator protein Pur-beta
E 458882 POLDIP3; polymerase delta-interacting protein 3 isoform X2 K22414 POLDIP3; polymerase delta-interacting protein 3
E 462805 ZC3H11A; zinc finger CCCH domain-containing protein 11A K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 112209478 LOW QUALITY PROTEIN: zinc finger CCCH domain-containing protein 11A-like K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 112209525 zinc finger CCCH domain-containing protein 11A-like K22415 ZC3H11; zinc finger CCCH domain-containing protein 11
E 107966444 LENG8; leukocyte receptor cluster member 8 isoform X5 K23802 LENG8; SAC3 family protein LENG8/THP3
E 742949 PATL2; protein PAT1 homolog 2 isoform X2 K24823 PATL2; protein PAT1 homolog 2
C Surveillance factors
D Surveillance complex
E 462098 ETF1; eukaryotic peptide chain release factor subunit 1 isoform X1 K03265 ETF1; peptide chain release factor subunit 1
E 742431 GSPT2; eukaryotic peptide chain release factor GTP-binding subunit ERF3B K03267 ERF3; peptide chain release factor subunit 3
E 454075 GSPT1; eukaryotic peptide chain release factor GTP-binding subunit ERF3A isoform X1 K03267 ERF3; peptide chain release factor subunit 3
E 456373 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 450304 UPF2; regulator of nonsense transcripts 2 K14327 UPF2; regulator of nonsense transcripts 2
E 452689 UPF3A; regulator of nonsense transcripts 3A isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
E 465954 UPF3B; regulator of nonsense transcripts 3B isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
D Protein phosphatase 2A
E 464100 PPP2CB; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 471633 serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 100614247 PPP2CA; serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform K04382 PPP2C; serine/threonine-protein phosphatase 2A catalytic subunit [EC:3.1.3.16]
E 468983 PPP2R1A; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 466778 PPP2R1B; serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform K03456 PPP2R1; serine/threonine-protein phosphatase 2A regulatory subunit A
E 464068 PPP2R2A; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform isoform X1 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 462170 PPP2R2B; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform isoform X5 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 466265 PPP2R2D; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform isoform X5 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 461101 PPP2R2C; protein phosphatase 2, regulatory subunit B, gamma isoform X6 K04354 PPP2R2; serine/threonine-protein phosphatase 2A regulatory subunit B
E 452859 PPP2R3C; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 460715 PPP2R3A; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha isoform X3 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 107972993 LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta-like K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 112207609 serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta-like isoform X1 K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 100609914 LOW QUALITY PROTEIN: serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta K11583 PPP2R3; serine/threonine-protein phosphatase 2A regulatory subunit B''
E 453170 PPP2R5C; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 462705 PPP2R5D; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 457716 PPP2R5A; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 452962 PPP2R5E; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
E 451305 PPP2R5B; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform isoform X1 K11584 PPP2R5; serine/threonine-protein phosphatase 2A regulatory subunit B'
D Other surveillance factors
E 453961 SMG1; serine/threonine-protein kinase SMG1 isoform X1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 107968716 SMG5; protein SMG5 isoform X1 K11125 SMG5; protein SMG5
E 454417 SMG6; telomerase-binding protein EST1A isoform X1 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 457572 SMG7; protein SMG7 isoform X1 K14409 SMG7; protein SMG7
E 468293 SMG8; protein SMG8 K18734 SMG8; protein SMG8
E 456097 SMG9; protein SMG9 K18735 SMG9; protein SMG9
E 460017 GIGYF2; GRB10-interacting GYF protein 2 isoform X4 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 472671 GIGYF1; GRB10-interacting GYF protein 1 isoform X1 K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein
E 464583 SECISBP2; selenocysteine insertion sequence-binding protein 2 isoform X8 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 453416 SECISBP2L; selenocysteine insertion sequence-binding protein 2-like isoform X1 K19539 SECISBP2; selenocysteine insertion sequence-binding protein 2
E 456163 DHX34; probable ATP-dependent RNA helicase DHX34 K20101 DHX34; ATP-dependent RNA helicase DHX34 [EC:5.6.2.6]
E 458836 GTPBP1; GTP-binding protein 1 isoform X2 K24887 GTPBP1; GTP-binding protein 1
C Factors involved in mRNA localization
D Cargo complex
E 464968 PUM3; pumilio homolog 3 K14844 PUF6; pumilio homology domain family member 6
E 450136 MYO5A; unconventional myosin-Va isoform X7 K10357 MYO5; myosin V
E 453441 MYO5C; unconventional myosin-Vc isoform X2 K10357 MYO5; myosin V
E 455415 MYO5B; unconventional myosin-Vb isoform X1 K10357 MYO5; myosin V
E 465233 BICD2; protein bicaudal D homolog 2 isoform X1 K18739 BICD; protein bicaudal D
E 465268 BICD1; protein bicaudal D homolog 1 isoform X6 K18739 BICD; protein bicaudal D
E 467661 EXD1; piRNA biogenesis protein EXD1 isoform X1 K18740 EXD1; exonuclease 3'-5' domain-containing protein 1
D Factors that have mRNA localization signals
E 746570 ACTG1; actin, cytoplasmic 2 K05692 ACTB_G1; actin beta/gamma 1
E 450133 ACTB; actin, cytoplasmic 1 K05692 ACTB_G1; actin beta/gamma 1
E 455522 MBP; myelin basic protein K17269 MBP; myelin basic protein
E 493952 VIM; vimentin K07606 VIM; vimentin
E 100609360 MT1M; metallothionein-1M K14739 MT1_2; metallothionein 1/2
E 467981 metallothionein-1B K14739 MT1_2; metallothionein 1/2
E 736020 MT1L; metallothionein-1L K14739 MT1_2; metallothionein 1/2
E 471221 MT2A; metallothionein-2 K14739 MT1_2; metallothionein 1/2
E 100609808 MT1F; metallothionein-1F K14739 MT1_2; metallothionein 1/2
E 736169 MT1G; metallothionein-1G K14739 MT1_2; metallothionein 1/2
E 736361 MT1H; metallothionein-1H K14739 MT1_2; metallothionein 1/2
E 100609276 MT1E; metallothionein-1E K14739 MT1_2; metallothionein 1/2
E 100616506 MT1X; metallothionein-1X K14739 MT1_2; metallothionein 1/2
E 100609521 MT1A; metallothionein-1A K14739 MT1_2; metallothionein 1/2
E 100612511 MT1HL1; metallothionein 1H-like protein 1 K14739 MT1_2; metallothionein 1/2
E 101058101 metallothionein-1L K14739 MT1_2; metallothionein 1/2
E 464393 MYC; myc proto-oncogene protein K04377 MYC; Myc proto-oncogene protein
E 100612281 GDF1; embryonic growth/differentiation factor 1 K05495 GDF1; growth differentiation factor 1
E 467944 TBX6; T-box transcription factor TBX6 K10180 TBX6; T-box protein 6
E 104008328 NANOS1; nanos homolog 1 K18741 NANOS1; protein nanos 1
D Trans-acting binding proteins
E 746148 ZBP1; Z-DNA-binding protein 1 isoform X1 K12965 ZBP1; Z-DNA binding protein 1
E 455640 KHSRP; far upstream element-binding protein 2 isoform X1 K13210 FUBP; far upstream element-binding protein
E 456968 FUBP1; far upstream element-binding protein 1 isoform X4 K13210 FUBP; far upstream element-binding protein
E 464800 FUBP3; far upstream element-binding protein 3 isoform X6 K13210 FUBP; far upstream element-binding protein
E 494136 EEF1A1; elongation factor 1-alpha 1 K03231 EEF1A; elongation factor 1-alpha
E 739210 putative elongation factor 1-alpha-like 3 K03231 EEF1A; elongation factor 1-alpha
E 458406 EEF1A2; elongation factor 1-alpha 2 K03231 EEF1A; elongation factor 1-alpha
E 107971165 putative elongation factor 1-alpha-like 3 K03231 EEF1A; elongation factor 1-alpha
E 451253 EEF1G; elongation factor 1-gamma K03233 EEF1G; elongation factor 1-gamma
E 463299 HNRNPA2B1; heterogeneous nuclear ribonucleoproteins A2/B1 isoform X2 K13158 HNRNPA2B1; heterogeneous nuclear ribonucleoprotein A2/B1
E 457347 HAX1; HCLS1-associated protein X-1 isoform X2 K16220 HAX1; HCLS1-associated protein X-1
E 459990 AGFG1; arf-GAP domain and FG repeat-containing protein 1 isoform X1 K15044 AGFG1; Arf-GAP domain and FG repeats-containing protein 1
E 458319 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 464233 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X3 K17597 STAU; double-stranded RNA-binding protein Staufen
E 744246 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3 isoform X1 K13197 IGF2BP3; insulin-like growth factor 2 mRNA-binding protein 3
E 749887 PTBP1; polypyrimidine tract-binding protein 1 isoform X2 K13218 PTBP1; polypyrimidine tract-binding protein 1
E 467743 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 461123 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 462277 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 739487 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
D Other mRNA localization factors
E 465894 FMR1; synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 746398 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X7 K15516 FMR; fragile X mental retardation protein
E 749002 FXR2; fragile X mental retardation syndrome-related protein 2 isoform X1 K15516 FMR; fragile X mental retardation protein
E 462221 CYFIP2; cytoplasmic FMR1-interacting protein 2 isoform X1 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 453278 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X4 K05749 CYFIP; cytoplasmic FMR1 interacting protein
E 467006 PCBP2; poly(rC)-binding protein 2 isoform X1 K13162 PCBP2; poly(rC)-binding protein 2
E 460410 PCBP4; poly(rC)-binding protein 4 isoform X2 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 112206646 PCBP3; poly(rC)-binding protein 3 isoform X1 K21444 PCBP3_4; poly(rC)-binding protein 3/4
E 451114 CAPRIN1; caprin-1 K18743 CAPRIN1; caprin-1
E 465366 CAPRIN2; caprin-2 isoform X9 K18744 CAPRIN2; caprin-2
E 100612240 uncharacterized protein LOC100612240 K09276 YBX1; Y-box-binding protein 1
E 107966249 YBX1; nuclease-sensitive element-binding protein 1 isoform X1 K09276 YBX1; Y-box-binding protein 1
C mRNA cycle factors
D Common to processing body (P body) and stress granule
E 460744 XRN1; 5'-3' exoribonuclease 1 isoform X2 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 456747 AGO1; protein argonaute-1 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 469279 AGO3; protein argonaute-3 isoform X2 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 469278 AGO4; protein argonaute-4 isoform X1 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 737376 AGO2; protein argonaute-2 isoform X3 K11593 ELF2C; eukaryotic translation initiation factor 2C
E 460015 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X2 K03259 EIF4E; translation initiation factor 4E
E 462294 EIF4E1B; eukaryotic translation initiation factor 4E type 1B isoform X1 K03259 EIF4E; translation initiation factor 4E
E 461391 EIF4E; eukaryotic translation initiation factor 4E K03259 EIF4E; translation initiation factor 4E
E 456373 UPF1; regulator of nonsense transcripts 1 isoform X1 K14326 UPF1; regulator of nonsense transcripts 1 [EC:5.6.2.5 5.6.2.3]
E 742915 DDX3X; ATP-dependent RNA helicase DDX3X isoform X1 K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:5.6.2.7]
E 449508 DDX3Y; ATP-dependent RNA helicase DDX3Y K17642 DDX3Y; ATP-dependent RNA helicase DDX3Y [EC:5.6.2.7]
E 112204056 ATP-dependent RNA helicase DDX3Y isoform X1 K17642 DDX3Y; ATP-dependent RNA helicase DDX3Y [EC:5.6.2.7]
E 451594 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 455423 MEX3C; RNA-binding E3 ubiquitin-protein ligase MEX3C K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 457383 MEX3A; RNA-binding protein MEX3A K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 467742 MEX3B; RNA-binding protein MEX3B K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 468649 MEX3D; RNA-binding protein MEX3D K15686 MEX3; RNA-binding protein MEX3 [EC:2.3.2.27]
E 472626 FASTK; fas-activated serine/threonine kinase K08290 FASTK; Fas-activated serine/threonine kinase [EC:2.7.11.8]
E 455937 LSM14A; protein LSM14 homolog A isoform X3 K18749 LSM14; protein LSM14
E 458382 LSM14B; protein LSM14 homolog B isoform X1 K18749 LSM14; protein LSM14
E 459300 PCBP1; poly(rC)-binding protein 1 K12889 PCBP1; poly(rC)-binding protein 1
E 467006 PCBP2; poly(rC)-binding protein 2 isoform X1 K13162 PCBP2; poly(rC)-binding protein 2
E 100612240 uncharacterized protein LOC100612240 K09276 YBX1; Y-box-binding protein 1
E 107966249 YBX1; nuclease-sensitive element-binding protein 1 isoform X1 K09276 YBX1; Y-box-binding protein 1
E 452791 AJUBA; LIM domain-containing protein ajuba isoform X1 K16682 AJUBA; LIM domain-containing protein
E 747259 WTIP; Wilms tumor protein 1-interacting protein K16682 AJUBA; LIM domain-containing protein
E 471102 LIMD1; LIM domain-containing protein 1 isoform X1 K16682 AJUBA; LIM domain-containing protein
E 748253 APOBEC1; C->U-editing enzyme APOBEC-1 isoform X1 K16932 APOBEC1; C->U-editing enzyme APOBEC1 [EC:3.5.4.36]
E 470214 APOBEC3H; DNA dC->dU-editing enzyme APOBEC-3H K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 470275 DNA dC->dU-editing enzyme APOBEC-3F isoform X2 K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 100611714 APOBEC3C; DNA dC->dU-editing enzyme APOBEC-3C K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 467121 LOW QUALITY PROTEIN: DNA dC->dU-editing enzyme APOBEC-3G-like K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 470274 APOBEC3D; DNA dC->dU-editing enzyme APOBEC-3D K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 743891 APOBEC3B; DNA dC->dU-editing enzyme APOBEC-3B K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 744498 APOBEC3A; DNA dC->dU-editing enzyme APOBEC-3A K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 449577 APOBEC3G; DNA dC->dU-editing enzyme APOBEC-3G K18750 APOBEC3; C->U-editing enzyme APOBEC3 [EC:3.5.4.-]
E 457099 MOV10; putative helicase MOV-10 isoform X1 K18422 MOV10; helicase MOV-10 [EC:5.6.2.5]
E 100614798 PNRC2; proline-rich nuclear receptor coactivator 2 K18751 PNRC2; proline-rich nuclear receptor coactivator 2
E 461817 TNPO1; transportin-1 isoform X1 K18752 TNPO1; transportin-1
E 453961 SMG1; serine/threonine-protein kinase SMG1 isoform X1 K08873 SMG1; serine/threonine-protein kinase SMG1 [EC:2.7.11.1]
E 107968716 SMG5; protein SMG5 isoform X1 K11125 SMG5; protein SMG5
E 454417 SMG6; telomerase-binding protein EST1A isoform X1 K11124 SMG6; protein SMG6 [EC:3.1.-.-]
E 457572 SMG7; protein SMG7 isoform X1 K14409 SMG7; protein SMG7
E 736203 ZFP36; mRNA decay activator protein ZFP36 K15308 TTP; tristetraprolin
E 452992 ZFP36L1; mRNA decay activator protein ZFP36L1 K18753 ZFP36L; butyrate response factor
E 459185 ZFP36L2; mRNA decay activator protein ZFP36L2 K18753 ZFP36L; butyrate response factor
E 456661 LIN28A; protein lin-28 homolog A K18754 LIN28; protein lin-28
E 737588 LIN28B; protein lin-28 homolog B isoform X3 K18754 LIN28; protein lin-28
E 461084 HTT; huntingtin isoform X1 K04533 HD; huntingtin
E 473395 IPO8; importin-8 isoform X1 K18755 IPO8; importin-8
E 450473 BICC1; protein bicaudal C homolog 1 isoform X1 K18756 BICC1; protein bicaudal C
E 470592 HNRNPA3; heterogeneous nuclear ribonucleoprotein A3 isoform X1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 739306 HNRPA1LK1; heterogeneous nuclear ribonucleoprotein A1-like 1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 464260 heterogeneous nuclear ribonucleoprotein A1-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 747284 HNRNPA1; heterogeneous nuclear ribonucleoprotein A1 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 746306 heterogeneous nuclear ribonucleoprotein A1-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 737627 heterogeneous nuclear ribonucleoprotein A1-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 101059544 heterogeneous nuclear ribonucleoprotein A1-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 104001099 HNRNPA1L2; LOW QUALITY PROTEIN: heterogeneous nuclear ribonucleoprotein A1-like 2 K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 107973587 heterogeneous nuclear ribonucleoprotein A3-like K12741 HNRNPA1_3; heterogeneous nuclear ribonucleoprotein A1/A3
E 469367 PRKACB; cAMP-dependent protein kinase catalytic subunit beta isoform X11 K04345 PKA; protein kinase A [EC:2.7.11.11]
E 472944 PRKACG; cAMP-dependent protein kinase catalytic subunit gamma K04345 PKA; protein kinase A [EC:2.7.11.11]
E 107966260 PRKACA; cAMP-dependent protein kinase catalytic subunit alpha isoform X1 K04345 PKA; protein kinase A [EC:2.7.11.11]
E 462356 LARP1; la-related protein 1 isoform X1 K18757 LARP1; la-related protein 1
E 461482 LARP1B; la-related protein 1B isoform X7 K18757 LARP1; la-related protein 1
E 452247 ATXN2; ataxin-2 isoform X1 K23625 ATXN2_2L; ataxin 2/2L
E 454017 ATXN2L; ataxin-2-like protein isoform X1 K23625 ATXN2_2L; ataxin 2/2L
D P-body specific factors
E 462001 DCP2; m7GpppN-mRNA hydrolase isoform X1 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 460444 DCP1A; mRNA-decapping enzyme 1A isoform X2 K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 451743 DCP1B; mRNA-decapping enzyme 1B isoform X1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 746776 LSM1; U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 462569 LSM2; U6 snRNA-associated Sm-like protein LSm2 isoform X2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 742889 LSM3; U6 snRNA-associated Sm-like protein LSm3 isoform X1 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 747984 LSM4; U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 463335 LSM5; U6 snRNA-associated Sm-like protein LSm5 isoform X2 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 100613876 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 455572 LSM7; U6 snRNA-associated Sm-like protein LSm7 isoform X2 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 736972 LSM8; LSM8 homolog, U6 small nuclear RNA associated isoform X2 K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
E 466670 KLC2; kinesin light chain 2 isoform X1 K10407 KLC; kinesin light chain
E 468918 KLC3; kinesin light chain 3 isoform X1 K10407 KLC; kinesin light chain
E 735843 KLC4; kinesin light chain 4 isoform X1 K10407 KLC; kinesin light chain
E 453188 KLC1; kinesin light chain 1 isoform X11 K10407 KLC; kinesin light chain
E 450136 MYO5A; unconventional myosin-Va isoform X7 K10357 MYO5; myosin V
E 453441 MYO5C; unconventional myosin-Vc isoform X2 K10357 MYO5; myosin V
E 455415 MYO5B; unconventional myosin-Vb isoform X1 K10357 MYO5; myosin V
E 470654 TUBA4A; tubulin alpha-4A chain K07374 TUBA; tubulin alpha
E 451875 TUBA1A; tubulin alpha-1A chain K07374 TUBA; tubulin alpha
E 451876 TUBA1C; tubulin alpha-1C chain isoform X3 K07374 TUBA; tubulin alpha
E 458641 TUBA8; tubulin alpha-8 chain K07374 TUBA; tubulin alpha
E 452423 TUBA1B; tubulin alpha-1B chain K07374 TUBA; tubulin alpha
E 466007 TUBAL3; tubulin alpha chain-like 3 K07374 TUBA; tubulin alpha
E 736248 TUBA3E; tubulin alpha-3E chain K07374 TUBA; tubulin alpha
E 465169 TUBA3C; tubulin alpha-3 chain K07374 TUBA; tubulin alpha
E 104004490 LOW QUALITY PROTEIN: tubulin alpha-8 chain K07374 TUBA; tubulin alpha
E 107973630 LOW QUALITY PROTEIN: tubulin alpha-3 chain K07374 TUBA; tubulin alpha
E 467743 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 461123 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X3 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 462277 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X4 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 739487 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1 K02602 CPEB; cytoplasmic polyadenylation element-binding protein
E 471715 GEMIN5; gem-associated protein 5 isoform X1 K13133 GEMIN5; gem associated protein 5
E 461066 TACC3; transforming acidic coiled-coil-containing protein 3 isoform X1 K14283 TACC3; transforming acidic coiled-coil-containing protein 3
E 453997 TNRC6A; trinucleotide repeat-containing gene 6A protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 458852 TNRC6B; trinucleotide repeat-containing gene 6B protein isoform X1 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 741899 TNRC6C; trinucleotide repeat-containing gene 6C protein isoform X7 K18412 TNRC6; trinucleotide repeat-containing gene 6 protein
E 454137 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 452072 CNOT2; CCR4-NOT transcription complex subunit 2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 107969798 CNOT3; CCR4-NOT transcription complex subunit 3 isoform X1 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 463751 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X6 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 462338 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 467690 CNOT6L; CCR4-NOT transcription complex subunit 6-like isoform X5 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 462213 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 464006 CNOT7; CCR4-NOT transcription complex subunit 7 isoform X1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 455940 uncharacterized protein KIAA0355 homolog isoform X1 K26671 GARRE1; granule associated Rac and RHOG effector protein 1
E 460011 DIS3L2; DIS3-like exonuclease 2 isoform X1 K18758 DIS3L2; DIS3-like exonuclease 2 [EC:3.1.13.-]
E 101057768 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 736229 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
E 451538 BTG4; protein BTG4 isoform X1 K14443 TOB; protein Tob/BTG
E 452121 BTG1; protein BTG1 K14443 TOB; protein Tob/BTG
E 458865 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 468406 TOB1; protein Tob1 K14443 TOB; protein Tob/BTG
E 740912 BTG2; protein BTG2 K14443 TOB; protein Tob/BTG
E 749692 BTG3; protein BTG3 isoform X1 K14443 TOB; protein Tob/BTG
E 107970226 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X6 K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter
E 466618 PATL1; protein PAT1 homolog 1 isoform X1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
E 453743 EDC3; enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 454178 EDC4; enhancer of mRNA-decapping protein 4 isoform X4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 745748 NANOS2; nanos homolog 2 K18760 NANOS2; protein nanos 2
E 747879 NANOS3; nanos homolog 3 K18761 NANOS3; protein nanos 3
E 450304 UPF2; regulator of nonsense transcripts 2 K14327 UPF2; regulator of nonsense transcripts 2
E 452689 UPF3A; regulator of nonsense transcripts 3A isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
E 465954 UPF3B; regulator of nonsense transcripts 3B isoform X1 K14328 UPF3; regulator of nonsense transcripts 3
E 450975 TRIM21; E3 ubiquitin-protein ligase TRIM21 K10651 TRIM21; tripartite motif-containing protein 21 [EC:2.3.2.27]
E 460252 TRIM71; E3 ubiquitin-protein ligase TRIM71 K12035 TRIM71; tripartite motif-containing protein 71 [EC:2.3.2.27]
E 740537 POLR2G; DNA-directed RNA polymerase II subunit RPB7 K03015 RPB7; DNA-directed RNA polymerase II subunit RPB7
E 459155 EIF2AK2; interferon-induced, double-stranded RNA-activated protein kinase K16195 EIF2AK2; eukaryotic translation initiation factor 2-alpha kinase 2 [EC:2.7.11.1]
E 739504 ZAR1; zygote arrest protein 1 K18762 ZAR1; zygote arrest protein 1
E 107971075 ZAR1-like protein K18762 ZAR1; zygote arrest protein 1
E 107967878 ZAR1L; ZAR1-like protein K18762 ZAR1; zygote arrest protein 1
E 464207 YTHDF3; YTH domain-containing family protein 3 isoform X1 K20102 YTHDF; YTH domain-containing family protein
E 470035 YTHDF1; YTH domain-containing family protein 1 isoform X2 K20102 YTHDF; YTH domain-containing family protein
E 740305 YTHDF2; YTH domain-containing family protein 2 K20102 YTHDF; YTH domain-containing family protein
D Stress granule specific factors
E 741374 TIAL1; nucleolysin TIAR isoform X2 K13201 TIA1; nucleolysin TIA-1/TIAR
E 459303 TIA1; nucleolysin TIA-1 isoform X6 K13201 TIA1; nucleolysin TIA-1/TIAR
E 465742 PABPC5; polyadenylate-binding protein 5 K13126 PABPC; polyadenylate-binding protein
E 458273 PABPC1L; polyadenylate-binding protein 1-like isoform X3 K13126 PABPC; polyadenylate-binding protein
E 452494 PABPC3; polyadenylate-binding protein 3 K13126 PABPC; polyadenylate-binding protein
E 471308 PABPC4L; polyadenylate-binding protein 4-like isoform X1 K13126 PABPC; polyadenylate-binding protein
E 456782 PABPC4; polyadenylate-binding protein 4 isoform X2 K13126 PABPC; polyadenylate-binding protein
E 464318 PABPC1; polyadenylate-binding protein 1 K13126 PABPC; polyadenylate-binding protein
E 100615000 polyadenylate-binding protein 1-like 2 K13126 PABPC; polyadenylate-binding protein
E 112204072 PABPC1L2A; polyadenylate-binding protein 1-like 2 K13126 PABPC; polyadenylate-binding protein
E 458319 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1 K17597 STAU; double-stranded RNA-binding protein Staufen
E 464233 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X3 K17597 STAU; double-stranded RNA-binding protein Staufen
E 465894 FMR1; synaptic functional regulator FMR1 isoform X1 K15516 FMR; fragile X mental retardation protein
E 746398 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X7 K15516 FMR; fragile X mental retardation protein
E 749002 FXR2; fragile X mental retardation syndrome-related protein 2 isoform X1 K15516 FMR; fragile X mental retardation protein
E 746148 ZBP1; Z-DNA-binding protein 1 isoform X1 K12965 ZBP1; Z-DNA binding protein 1
E 743010 ELAVL1; ELAV-like protein 1 K13088 ELAVL1; ELAV-like protein 1
E 471711 G3BP1; ras GTPase-activating protein-binding protein 1 K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:5.6.2.5 5.6.2.3]
E 461244 G3BP2; ras GTPase-activating protein-binding protein 2 isoform X2 K24983 G3BP2; Ras GTPase-activating protein-binding protein 2
E 470965 EIF2A; eukaryotic translation initiation factor 2A isoform X1 K15026 EIF2A; translation initiation factor 2A
E 472269 EIF3B; eukaryotic translation initiation factor 3 subunit B isoform X1 K03253 EIF3B; translation initiation factor 3 subunit B
E 460917 EIF4A2; eukaryotic initiation factor 4A-II K03257 EIF4A; translation initiation factor 4A
E 748995 EIF4A1; eukaryotic initiation factor 4A-I K03257 EIF4A; translation initiation factor 4A
E 454941 EIF4A3; eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 742589 eukaryotic initiation factor 4A-III K13025 EIF4A3; ATP-dependent RNA helicase [EC:5.6.2.7]
E 737509 EIF4B; eukaryotic translation initiation factor 4B isoform X2 K03258 EIF4B; translation initiation factor 4B
E 460888 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X11 K03260 EIF4G; translation initiation factor 4G
E 466443 EIF4G2; eukaryotic translation initiation factor 4 gamma 2 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 469204 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X1 K03260 EIF4G; translation initiation factor 4G
E 450110 RPS6KA3; ribosomal protein S6 kinase alpha-3 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 456664 RPS6KA1; ribosomal protein S6 kinase alpha-1 isoform X5 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 463127 RPS6KA2; ribosomal protein S6 kinase alpha-2 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 743327 RPS6KA6; ribosomal protein S6 kinase alpha-6 isoform X1 K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1]
E 462344 RACK1; receptor of activated protein C kinase 1 K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein
E 464876 TRAF2; TNF receptor-associated factor 2 isoform X1 K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27]
E 451267 NXF1; nuclear RNA export factor 1 K14284 NXF; nuclear RNA export factor
E 735423 nuclear RNA export factor 2 K14284 NXF; nuclear RNA export factor
E 465774 NXF3; nuclear RNA export factor 3 K14284 NXF; nuclear RNA export factor
E 100610724 NXF5; nuclear RNA export factor 5 K14284 NXF; nuclear RNA export factor
E 100611904 LOW QUALITY PROTEIN: nuclear RNA export factor 2-like K14284 NXF; nuclear RNA export factor
E 100610515 HDAC6; histone deacetylase 6 isoform X1 K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98]
E 452750 TDRD3; tudor domain-containing protein 3 isoform X4 K18404 TDRD3; tudor domain-containing protein 3
E 450259 LARP4B; la-related protein 4B isoform X1 K18763 LARP4; la-related protein 4
E 452428 LARP4; la-related protein 4 isoform X6 K18763 LARP4; la-related protein 4
B mRNA degradation factors
C 5'-3' decay
D Decapping complex
E 460444 DCP1A; mRNA-decapping enzyme 1A isoform X2 K12610 DCP1A; mRNA-decapping enzyme 1A [EC:3.-.-.-]
E 451743 DCP1B; mRNA-decapping enzyme 1B isoform X1 K12611 DCP1B; mRNA-decapping enzyme 1B [EC:3.-.-.-]
E 462001 DCP2; m7GpppN-mRNA hydrolase isoform X1 K12613 DCP2; mRNA-decapping enzyme subunit 2 [EC:3.6.1.62]
E 451594 DDX6; probable ATP-dependent RNA helicase DDX6 K12614 DDX6; ATP-dependent RNA helicase DDX6/DHH1 [EC:5.6.2.7]
E 453743 EDC3; enhancer of mRNA-decapping protein 3 K12615 EDC3; enhancer of mRNA-decapping protein 3
E 454178 EDC4; enhancer of mRNA-decapping protein 4 isoform X4 K12616 EDC4; enhancer of mRNA-decapping protein 4
E 466618 PATL1; protein PAT1 homolog 1 isoform X1 K12617 PATL1; DNA topoisomerase 2-associated protein PAT1
D Lsm complex
E 746776 LSM1; U6 snRNA-associated Sm-like protein LSm1 K12620 LSM1; U6 snRNA-associated Sm-like protein LSm1
E 462569 LSM2; U6 snRNA-associated Sm-like protein LSm2 isoform X2 K12621 LSM2; U6 snRNA-associated Sm-like protein LSm2
E 742889 LSM3; U6 snRNA-associated Sm-like protein LSm3 isoform X1 K12622 LSM3; U6 snRNA-associated Sm-like protein LSm3
E 747984 LSM4; U6 snRNA-associated Sm-like protein LSm4 K12623 LSM4; U6 snRNA-associated Sm-like protein LSm4
E 463335 LSM5; U6 snRNA-associated Sm-like protein LSm5 isoform X2 K12624 LSM5; U6 snRNA-associated Sm-like protein LSm5
E 100613876 LSM6; U6 snRNA-associated Sm-like protein LSm6 K12625 LSM6; U6 snRNA-associated Sm-like protein LSm6
E 455572 LSM7; U6 snRNA-associated Sm-like protein LSm7 isoform X2 K12626 LSM7; U6 snRNA-associated Sm-like protein LSm7
E 736972 LSM8; LSM8 homolog, U6 small nuclear RNA associated isoform X2 K12627 LSM8; U6 snRNA-associated Sm-like protein LSm8
D 5' exonucleases
E 460744 XRN1; 5'-3' exoribonuclease 1 isoform X2 K12618 XRN1; 5'-3' exoribonuclease 1 [EC:3.1.13.-]
E 458131 XRN2; 5'-3' exoribonuclease 2 isoform X3 K12619 XRN2; 5'-3' exoribonuclease 2 [EC:3.1.13.-]
E 107966544 NUDT16; U8 snoRNA-decapping enzyme K16855 NUDT16; U8 snoRNA-decapping enzyme [EC:3.6.1.62 3.6.1.64]
D Other 5'-3' decay factors
E 451655 DCPS; m7GpppX diphosphatase isoform X1 K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 454834 HELZ; probable helicase with zinc finger domain isoform X3 K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
C 3'-5' decay
D Core exosome factors
E 450651 EXOSC1; exosome complex component CSL4 isoform X1 K07573 CSL4; exosome complex component CSL4
E 107976800 EXOSC2; exosome complex component RRP4 isoform X2 K03679 RRP4; exosome complex component RRP4
E 465105 EXOSC3; exosome complex component RRP40 K03681 RRP40; exosome complex component RRP40
E 740889 EXOSC4; exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E 740020 EXOSC5; exosome complex component RRP46 K12590 RRP46; exosome complex component RRP46
E 468014 EXOSC6; exosome complex component MTR3 K12587 MTR3; exosome complex component MTR3
E 460313 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
E 467263 EXOSC8; exosome complex component RRP43 isoform X1 K12586 RRP43; exosome complex component RRP43
E 741653 EXOSC9; exosome complex component RRP45 isoform X1 K03678 RRP45; exosome complex component RRP45
D Exosome cofactors
E 452595 DIS3; exosome complex exonuclease RRP44 isoform X2 K12585 DIS3; exosome complex exonuclease DIS3/RRP44 [EC:3.1.13.-]
E 467710 DIS3L; DIS3-like exonuclease 1 isoform X3 K18681 DIS3L; DIS3-like exonuclease 1 [EC:3.1.13.-]
E 457944 EXOSC10; exosome component 10 K12591 RRP6; exosome complex exonuclease RRP6 [EC:3.1.13.-]
E 745296 C1D; nuclear nucleic acid-binding protein C1D K12592 C1D; exosome complex protein LRP1
E 454270 MPHOSPH6; M-phase phosphoprotein 6 isoform X2 K12593 MPHOSPH6; M-phase phosphoprotein 6, animal type
E 461595 DDX60L; probable ATP-dependent RNA helicase DDX60-like isoform X1 K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]
E 471343 DDX60; probable ATP-dependent RNA helicase DDX60 isoform X1 K20103 DDX60; ATP-dependent RNA helicase DDX60 [EC:5.6.2.7]
D TRAMP complex
E 461712 PAPD7; non-canonical poly(A) RNA polymerase PAPD7 isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 465160 PAPD5; non-canonical poly(A) RNA polymerase PAPD5 isoform X1 K03514 PAPD5_7; non-canonical poly(A) RNA polymerase PAPD5/7 [EC:2.7.7.19]
E 465098 ZCCHC7; zinc finger CCHC domain-containing protein 7 K12597 AIR1_2; protein AIR1/2
E 461870 MTREX; exosome RNA helicase MTR4 isoform X1 K12598 MTR4; ATP-dependent RNA helicase DOB1 [EC:5.6.2.6]
D Ski complex
E 462573 SKIV2L; helicase SKI2W isoform X1 K12599 SKI2; antiviral helicase SKI2 [EC:5.6.2.6]
E 461746 TTC37; tetratricopeptide repeat protein 37 isoform X1 K12600 SKI3; superkiller protein 3
E 453568 WDR61; WD repeat-containing protein 61 isoform X1 K12602 WDR61; WD repeat-containing protein 61
D Ccr4-NOT complex
E 462338 CNOT6; CCR4-NOT transcription complex subunit 6 isoform X1 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 467690 CNOT6L; CCR4-NOT transcription complex subunit 6-like isoform X5 K12603 CNOT6; CCR4-NOT transcription complex subunit 6 [EC:3.1.13.4]
E 454137 CNOT1; CCR4-NOT transcription complex subunit 1 isoform X1 K12604 CNOT1; CCR4-NOT transcription complex subunit 1
E 452072 CNOT2; CCR4-NOT transcription complex subunit 2 K12605 CNOT2; CCR4-NOT transcription complex subunit 2
E 107969798 CNOT3; CCR4-NOT transcription complex subunit 3 isoform X1 K12580 CNOT3; CCR4-NOT transcription complex subunit 3
E 463751 CNOT4; CCR4-NOT transcription complex subunit 4 isoform X6 K10643 CNOT4; CCR4-NOT transcription complex subunit 4 [EC:2.3.2.27]
E 462213 CNOT8; CCR4-NOT transcription complex subunit 8 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 464006 CNOT7; CCR4-NOT transcription complex subunit 7 isoform X1 K12581 CNOT7_8; CCR4-NOT transcription complex subunit 7/8
E 741696 CNOT9; CCR4-NOT transcription complex subunit 9 K12606 RCD1; CCR4-NOT transcription complex subunit 9
E 470780 CNOT10; CCR4-NOT transcription complex subunit 10 isoform X6 K12607 CNOT10; CCR4-NOT transcription complex subunit 10
D Pan complex
E 101057768 PAN2; PAN2-PAN3 deadenylation complex catalytic subunit PAN2 isoform X1 K12571 PAN2; PAB-dependent poly(A)-specific ribonuclease subunit 2 [EC:3.1.13.4]
E 736229 PAN3; PAN2-PAN3 deadenylation complex subunit PAN3 isoform X1 K12572 PAN3; PAB-dependent poly(A)-specific ribonuclease subunit 3
D Other 3'-5' decay factors
E 453936 PARN; poly(A)-specific ribonuclease PARN isoform X1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 463111 PNLDC1; poly(A)-specific ribonuclease PNLDC1 K01148 PARN; poly(A)-specific ribonuclease [EC:3.1.13.4]
E 460791 DHX36; ATP-dependent RNA helicase DHX36 isoform X2 K14442 DHX36; ATP-dependent RNA helicase DHX36 [EC:5.6.2.6]
E 451538 BTG4; protein BTG4 isoform X1 K14443 TOB; protein Tob/BTG
E 452121 BTG1; protein BTG1 K14443 TOB; protein Tob/BTG
E 458865 TOB2; protein Tob2 K14443 TOB; protein Tob/BTG
E 468406 TOB1; protein Tob1 K14443 TOB; protein Tob/BTG
E 740912 BTG2; protein BTG2 K14443 TOB; protein Tob/BTG
E 749692 BTG3; protein BTG3 isoform X1 K14443 TOB; protein Tob/BTG
E 471627 CSF2; granulocyte-macrophage colony-stimulating factor K05427 CSF2; granulocyte-macrophage colony-stimulating factor
E 100611804 NOCT; nocturnin isoform X1 K18764 NOCT; nocturnin [EC:3.1.3.108]
E 463978 ERI1; 3'-5' exoribonuclease 1 isoform X1 K18416 THEX1; 3'-5' exoribonuclease 1 [EC:3.1.-.-]
E 100610436 ERI2; ERI1 exoribonuclease 2 isoform X1 K18417 ERI2; ERI1 exoribonuclease 2 [EC:3.1.-.-]
E 451655 DCPS; m7GpppX diphosphatase isoform X1 K12584 DCPS; m7GpppX diphosphatase [EC:3.6.1.59]
E 461027 PDE12; 2',5'-phosphodiesterase 12 K19612 PDE12; 2',5'-phosphodiesterase [EC:3.1.13.4 3.1.4.-]
E 467731 IREB2; iron-responsive element-binding protein 2 isoform X2 K22416 IREB2; iron-responsive element-binding protein 2
E 454834 HELZ; probable helicase with zinc finger domain isoform X3 K25168 HELZ; helicase with zinc finger domain [EC:5.6.2.-]
E 100611129 HELZ2; helicase with zinc finger domain 2 isoform X1 K25165 HELZ2; 3'-5' exoribonuclease HELZ2 [EC:3.1.13.1 5.6.2.6]
E 453098 NRDE2; protein NRDE2 homolog isoform X2 K26109 NRDE2; nuclear exosome regulator NRDE2
E 743539 SAMD4A; protein Smaug homolog 1 isoform X7 K27396 SMG; protein Smaug
E 456020 SAMD4B; protein Smaug homolog 2 isoform X1 K27396 SMG; protein Smaug
E 465017 FOCAD; focadhesin isoform X1 K27498 FOCAD; focadhesin
C Other degradation factors
D RNases
E 465207 RNASE1; ribonuclease pancreatic precursor K01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]
E 473325 RNASE2; non-secretory ribonuclease precursor K01168 RNASE1_2; pancreatic ribonuclease [EC:4.6.1.18]
E 465205 RNASE4; ribonuclease 4 precursor K16632 RNASE4; ribonuclease 4 [EC:3.1.27.-]
E 473324 RNASE6; ribonuclease K6 precursor K01172 RNASE6_7_8; ribonuclease 6/7/8 [EC:3.1.27.-]
E 493984 RNASE8; ribonuclease 8 precursor K01172 RNASE6_7_8; ribonuclease 6/7/8 [EC:3.1.27.-]
E 100610073 RNASE7; ribonuclease 7 K01172 RNASE6_7_8; ribonuclease 6/7/8 [EC:3.1.27.-]
E 465202 RNASE11; probable ribonuclease 11 precursor K16633 RNASE11; ribonuclease 11 [EC:3.1.27.-]
E 456757 ZC3H12A; endoribonuclease ZC3H12A isoform X1 K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 466775 ZC3H12C; probable ribonuclease ZC3H12C isoform X3 K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 473644 ZC3H12B; probable ribonuclease ZC3H12B K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
E 463059 ZC3H12D; probable ribonuclease ZC3H12D isoform X1 K18668 ZC3H12; ribonuclease ZC3H12 [EC:3.1.-.-]
#
AProkaryotic type
B Bacterial mRNA degradation factors
C RNA degradosome components
D Ribonucreases
E 471576 DROSHA; ribonuclease 3 isoform X1 K03685 rnc; ribonuclease III [EC:3.1.26.3]
E 451561 REXO2; oligoribonuclease, mitochondrial isoform X2 K13288 orn; oligoribonuclease [EC:3.1.-.-]
D Helicases
D Other RNA degradosome components
E 454457 ENO3; beta-enolase isoform X2 K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 457913 ENO1; alpha-enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 749504 ENO2; gamma-enolase K01689 ENO1_2_3; enolase 1/2/3 [EC:4.2.1.11]
E 459247 PNPT1; polyribonucleotide nucleotidyltransferase 1, mitochondrial isoform X1 K00962 pnp; polyribonucleotide nucleotidyltransferase [EC:2.7.7.8]
E 450266 PFKP; ATP-dependent 6-phosphofructokinase, platelet type isoform X1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 451863 PFKM; ATP-dependent 6-phosphofructokinase, muscle type isoform X1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
E 458602 PFKL; ATP-dependent 6-phosphofructokinase, liver type isoform X1 K00850 pfkA; 6-phosphofructokinase 1 [EC:2.7.1.11]
C Other RNA degradation factors
D Chaperones
E 462099 HSPA9; stress-70 protein, mitochondrial isoform X1 K04043 dnaK; molecular chaperone DnaK
E 459852 HSPD1; 60 kDa heat shock protein, mitochondrial K04077 groEL; chaperonin GroEL [EC:5.6.1.7]
D Others
D Bacterial Small RNA Regulators
B Archeal mRNA degradation factors
C Exosome components
D Core exosome
E 107976800 EXOSC2; exosome complex component RRP4 isoform X2 K03679 RRP4; exosome complex component RRP4
E 450651 EXOSC1; exosome complex component CSL4 isoform X1 K07573 CSL4; exosome complex component CSL4
D Cofactors
E 740889 EXOSC4; exosome complex component RRP41 K11600 RRP41; exosome complex component RRP41
E 460313 EXOSC7; exosome complex component RRP42 K12589 RRP42; exosome complex component RRP42
D Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: April 25, 2024