+F Repair protein KO
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DNA Repair and Recombination Proteins - Saccharomonospora xinjiangensis
%
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AEukaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D EYD13_17430 ogt3; Methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D EYD13_04045 ogt2; Methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E EYD13_05015 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E EYD13_14225 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E EYD13_19635 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E EYD13_20010 pdg; Ultraviolet N-glycosylase/AP lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
D Long Patch-BER factors
E DNA polymerase delta complex
E DNA polymerase epsilon complex
D Short Patch-BER factors
D Other BER factors
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E XPC-HR23B-CETN2 complex
E Cul4-DDB2 complex
E NER4 complex
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase II complex
E Cul4-CSA complex
E Other TCR factor
D TFIIH complex
E EYD13_19075 Type III restriction enzyme, res subunit K10843 ERCC3; DNA excision repair protein ERCC-3 [EC:5.6.2.4]
D RPA (replication factor A)
D Other NER factors
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D MutL homologs
D DNA polymerase delta complex
D RPA (replication factor A)
D RFC (replication factor C)
D Other MMR factors
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D MRN(MRX) complex
D BRCA1-core complex
D BRCA1-A complex
D BRCA1-B complex
D BRCA1-C complex
D BRCA complex
D RecA family proteins
D Rad52 family proteins
D Rad54 family proteins
D RecQ family DNA helicases
D Bloom's syndrome complex (BTR)
D RPA (replication factor A)
D Protein phosphatase 4
D AP-5 complex
D SMC5-SMC6 complex
D Other HR factors
C NHEJ (non-homologous end-joining)
D DNA-PK complex
D MRX complex
D DNA Ligase 4 complex
D X-family DNA polymerases
D Other NHEJ factors
C FA (Fanconi anemia) pathway
D FA core complex
D FA core complex binding factors
D Bloom's syndrome complex (BTR)
D FANCD2-I complex
D Downstream FA components
D Other FA pathway factors
C Other DSBR factors
D Protein phosphatase 6
D Ubiquitin ligases
D Others
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
C B-family DNA polymerases
C A-family DNA polymerase
C Rad6 epistasis group
C Other TLS factors
B Check point factors
C Rad9-Hus1-Rad1 complex
C HRAD17(Rad24)-RFC complex
C Rad17-Mec3-Ddc1 complex
C FPC (fork protection complex)
C Triple T complex
C BAG6-UBL4A-GET4 complex
C Other check point factors
B Other factors with a suspected DNA repair function
C DNA polymerases
C Nucleases
C Helicases
C PSO4 complex
C Modulation of nucleotide pools
D EYD13_17305 nudG2; CTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EYD13_01085 nudG1; CTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EYD13_03680 Bifunctional NMN adenylyltransferase/Nudix hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EYD13_13850 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EYD13_14340 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EYD13_13555 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
#
AProkaryotic type
B SSBR (single strand breaks repair)
C Direct repair
D EYD13_17430 ogt3; Methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
D EYD13_04045 ogt2; Methylated-DNA--protein-cysteine methyltransferase K00567 ogt; methylated-DNA-[protein]-cysteine S-methyltransferase [EC:2.1.1.63]
C BER (base exicision repair)
D DNA glycosylases
E EYD13_05015 ung; Uracil-DNA glycosylase K03648 UNG; uracil-DNA glycosylase [EC:3.2.2.27]
E EYD13_07045 Uracil DNA glycosylase superfamily protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E EYD13_17930 Uracil DNA glycosylase superfamily protein K21929 udg; uracil-DNA glycosylase [EC:3.2.2.27]
E EYD13_17425 alkA2; DNA-3-methyladenine glycosylase 2 K13529 ada-alkA; AraC family transcriptional regulator, regulatory protein of adaptative response / DNA-3-methyladenine glycosylase II [EC:3.2.2.21]
E EYD13_14225 3-methyladenine DNA glycosylase K03652 MPG; DNA-3-methyladenine glycosylase [EC:3.2.2.21]
E EYD13_19635 mutY; A/G-specific adenine glycosylase K03575 mutY; A/G-specific adenine glycosylase [EC:3.2.2.31]
E EYD13_03565 tag; DNA-3-methyladenine glycosylase 1 K01246 tag; DNA-3-methyladenine glycosylase I [EC:3.2.2.20]
E EYD13_05155 fpg2; Formamidopyrimidine-DNA glycosylase 1 K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E EYD13_00470 fpg1; putative formamidopyrimidine-DNA glycosylase-like protein K10563 mutM; formamidopyrimidine-DNA glycosylase [EC:3.2.2.23 4.2.99.18]
E EYD13_06580 nei1; Endonuclease 8 1 K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E EYD13_13980 nei2; Endonuclease 8 K05522 nei; endonuclease VIII [EC:3.2.2.- 4.2.99.18]
E EYD13_20010 pdg; Ultraviolet N-glycosylase/AP lyase K10773 NTHL1; endonuclease III [EC:3.2.2.- 4.2.99.18]
D AP endonucleases
E EYD13_08945 xthA; Exodeoxyribonuclease III K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E EYD13_02880 exoA; Exodeoxyribonuclease K01142 E3.1.11.2; exodeoxyribonuclease III [EC:3.1.11.2]
E EYD13_21790 end; putative endonuclease 4 K01151 nfo; deoxyribonuclease IV [EC:3.1.21.2]
E EYD13_18650 nfi; Endonuclease V K05982 E3.1.21.7; deoxyribonuclease V [EC:3.1.21.7]
D RecJ
D DNA ligase
E EYD13_04780 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D DNA polymerase I
E EYD13_14445 polA3; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
C NER (nucleotide excision repair)
D GGR (global genome repair) factors
E EYD13_14320 uvrA2; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
E EYD13_14380 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
E EYD13_08950 uvrC; UvrABC system protein C K03703 uvrC; excinuclease ABC subunit C
E EYD13_02735 uvrD1; ATP-dependent DNA helicase UvrD1 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E EYD13_03825 pcrA2; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E EYD13_04130 uvrD2; ATP-dependent DNA helicase UvrD2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E EYD13_14445 polA3; DNA polymerase I K02335 polA; DNA polymerase I [EC:2.7.7.7]
E EYD13_04780 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D TCR (transcription coupled repair) factors
E DNA-directed RNA polymerase complex (RNAP)
F EYD13_02190 rpoB; DNA-directed RNA polymerase subunit beta K03043 rpoB; DNA-directed RNA polymerase subunit beta [EC:2.7.7.6]
F EYD13_02195 rpoC; DNA-directed RNA polymerase subunit beta' K03046 rpoC; DNA-directed RNA polymerase subunit beta' [EC:2.7.7.6]
F EYD13_02415 rpoA; DNA-directed RNA polymerase subunit alpha K03040 rpoA; DNA-directed RNA polymerase subunit alpha [EC:2.7.7.6]
F EYD13_08865 rpoZ; DNA-directed RNA polymerase subunit omega K03060 rpoZ; DNA-directed RNA polymerase subunit omega [EC:2.7.7.6]
E TRCF (transcription-repair coupling factor)
F EYD13_17990 mfd; Transcription-repair-coupling factor K03723 mfd; transcription-repair coupling factor (superfamily II helicase) [EC:5.6.2.4]
C MMR (mismatch excision repair)
D Mismatch and loop recognition factors
D Molecular matchmaker
D Strand discrimination factor
D DNA exonucleases
E EYD13_17465 xseA; Exodeoxyribonuclease 7 large subunit K03601 xseA; exodeoxyribonuclease VII large subunit [EC:3.1.11.6]
E EYD13_17470 exodeoxyribonuclease VII small subunit K03602 xseB; exodeoxyribonuclease VII small subunit [EC:3.1.11.6]
D DNA polymerase III holoenzyme
E EYD13_10540 dnaE2; DNA polymerase III subunit alpha K02337 dnaE; DNA polymerase III subunit alpha [EC:2.7.7.7]
E EYD13_00010 dnaN; DNA polymerase III subunit beta K02338 dnaN; DNA polymerase III subunit beta [EC:2.7.7.7]
E EYD13_06895 hypothetical protein K02340 holA; DNA polymerase III subunit delta [EC:2.7.7.7]
E EYD13_19850 dnaX; DNA polymerase III subunit tau K02341 holB; DNA polymerase III subunit delta' [EC:2.7.7.7]
E EYD13_05855 polC; DNA polymerase III PolC-type K02342 dnaQ; DNA polymerase III subunit epsilon [EC:2.7.7.7]
D DNA ligase
E EYD13_04780 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
D Other MMR factors
E EYD13_02735 uvrD1; ATP-dependent DNA helicase UvrD1 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E EYD13_03825 pcrA2; ATP-dependent DNA helicase PcrA K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E EYD13_04130 uvrD2; ATP-dependent DNA helicase UvrD2 K03657 uvrD; ATP-dependent DNA helicase UvrD/PcrA [EC:5.6.2.4]
E EYD13_21810 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
E EYD13_17835 vsr; Very short patch repair protein K07458 vsr; DNA mismatch endonuclease, patch repair protein [EC:3.1.-.-]
B DSBR (double strand breaks repair)
C HR (homologous recombination)
D RecBC pathway proteins
E EYD13_15230 DNA recombination protein RecA K03553 recA; recombination protein RecA
E EYD13_08590 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E EYD13_08595 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E EYD13_08585 ruvC; Crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
E EYD13_08885 priA1; Primosomal protein N' K04066 priA; primosomal protein N' (replication factor Y) (superfamily II helicase) [EC:5.6.2.4]
E EYD13_17435 sbcC; Nuclease SbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50
E EYD13_17440 sbcD; Nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
D RecFOR pathway proteins
E EYD13_15230 DNA recombination protein RecA K03553 recA; recombination protein RecA
E EYD13_19510 hypothetical protein K04485 radA; DNA repair protein RadA/Sms
E EYD13_00020 recF; DNA replication and repair protein RecF K03629 recF; DNA replication and repair protein RecF
E EYD13_05030 recG; ATP-dependent DNA helicase RecG K03655 recG; ATP-dependent DNA helicase RecG [EC:5.6.2.4]
E EYD13_07375 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
E EYD13_20265 recR; Recombination protein RecR K06187 recR; recombination protein RecR
E EYD13_14165 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
E EYD13_08590 ruvA; Holliday junction ATP-dependent DNA helicase RuvA K03550 ruvA; holliday junction DNA helicase RuvA
E EYD13_08595 ruvB; Holliday junction ATP-dependent DNA helicase RuvB K03551 ruvB; holliday junction DNA helicase RuvB [EC:5.6.2.4]
E EYD13_08585 ruvC; Crossover junction endodeoxyribonuclease RuvC K01159 ruvC; crossover junction endodeoxyribonuclease RuvC [EC:3.1.21.10]
D AddAB pathway proteins
D Other HR factor
D Archaeal homologous recombinant proteins
E EYD13_17435 sbcC; Nuclease SbcCD subunit C K03546 sbcC; DNA repair protein SbcC/Rad50
E EYD13_17440 sbcD; Nuclease SbcCD subunit D K03547 sbcD; DNA repair protein SbcD/Mre11
C NHEJ (non-homologous end-joining)
D Two-component NHEJ DNA repair complex
E EYD13_01015 ykoV; putative DNA repair protein YkoV K10979 ku; DNA end-binding protein Ku
E EYD13_10390 Putative DNA ligase-like protein K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E EYD13_19395 Putative DNA ligase-like protein K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
E EYD13_19400 Putative DNA ligase-like protein K01971 ligD; bifunctional non-homologous end joining protein LigD [EC:6.5.1.1]
D SHIIR (short-homology-independent illegitimate recombination)
E Facilitator
F EYD13_00035 gyrA1; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F EYD13_04460 gyrA2; DNA gyrase subunit A K02469 gyrA; DNA gyrase subunit A [EC:5.6.2.2]
F EYD13_00030 gyrB1; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F EYD13_04455 gyrB2; DNA gyrase subunit B K02470 gyrB; DNA gyrase subunit B [EC:5.6.2.2]
F EYD13_19865 topA; DNA topoisomerase 1 K03168 topA; DNA topoisomerase I [EC:5.6.2.1]
E Supressor
F EYD13_04945 hypothetical protein K03530 hupB; DNA-binding protein HU-beta
D SHDIR (short-homology-dependent illegitimate recombination)
E RecET pathway
F EYD13_07375 recO; DNA repair protein RecO K03584 recO; DNA repair protein RecO (recombination protein O)
F EYD13_20265 recR; Recombination protein RecR K06187 recR; recombination protein RecR
F EYD13_04780 ligA; DNA ligase K01972 E6.5.1.2; DNA ligase (NAD+) [EC:6.5.1.2]
E Facilitator
E Supressor
F EYD13_18465 recQ2; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F EYD13_16620 recQ1; ATP-dependent DNA helicase RecQ K03654 recQ; ATP-dependent DNA helicase RecQ [EC:5.6.2.4]
F EYD13_14320 uvrA2; UvrABC system protein A K03701 uvrA; excinuclease ABC subunit A
F EYD13_14380 uvrB; UvrABC system protein B K03702 uvrB; excinuclease ABC subunit B
B TLS (translesion DNA synthesis) factors
C Y-family DNA polymerases
D EYD13_13965 dinB2; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
D EYD13_04450 dinB1; DNA polymerase IV K02346 dinB; DNA polymerase IV [EC:2.7.7.7]
C Other SOS response factors
D EYD13_15230 DNA recombination protein RecA K03553 recA; recombination protein RecA
D EYD13_15125 lexA; LexA repressor K01356 lexA; repressor LexA [EC:3.4.21.88]
D EYD13_14165 recN; DNA repair protein RecN K03631 recN; DNA repair protein RecN (Recombination protein N)
D EYD13_02800 DNA polymerase IV K14161 imuB; protein ImuB
D EYD13_02805 dnaE1; Error-prone DNA polymerase K14162 dnaE2; error-prone DNA polymerase [EC:2.7.7.7]
D EYD13_21810 ssb; Single-stranded DNA-binding protein K03111 ssb; single-strand DNA-binding protein
D EYD13_15225 recX; Regulatory protein RecX K03565 recX; regulatory protein
B Other factors with a suspected DNA repair function
C DNA polymerase
C DNA helicases
D EYD13_16180 dinG; putative ATP-dependent helicase DinG K03722 dinG; ATP-dependent DNA helicase DinG [EC:5.6.2.3]
D EYD13_02940 putative DEAD-box ATP-dependent RNA helicase K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
D EYD13_15250 putative ATP-dependent helicase Lhr K03724 lhr; ATP-dependent helicase Lhr and Lhr-like helicase [EC:5.6.2.6 5.6.2.4]
C Modulation of nucleotide pools
D EYD13_17305 nudG2; CTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EYD13_01085 nudG1; CTP pyrophosphohydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EYD13_03680 Bifunctional NMN adenylyltransferase/Nudix hydrolase K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EYD13_13850 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EYD13_14340 hypothetical protein K03574 mutT; 8-oxo-dGTP diphosphatase [EC:3.6.1.55]
D EYD13_04950 mutT1; Putative mutator protein MutT4 K23258 mutT1; 8-oxo-(d)GTP phosphatase [EC:3.6.1.69]
D EYD13_14145 nudF1; ADP-ribose pyrophosphatase K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D EYD13_16270 nudF2; ADP-ribose pyrophosphatase K01554 K01554; 8-oxo-dGDP phosphatase [EC:3.6.1.58]
D EYD13_13555 dut; Deoxyuridine 5'-triphosphate nucleotidohydrolase K01520 dut; dUTP diphosphatase [EC:3.6.1.23]
D EYD13_09315 nrdA; Ribonucleoside-diphosphate reductase 1 subunit alpha K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D EYD13_15110 nrdJ; Vitamin B12-dependent ribonucleotide reductase K00525 E1.17.4.1A; ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
D EYD13_09310 nrdB1; Ribonucleoside-diphosphate reductase subunit beta K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
D EYD13_18885 nrdB2; R2-like ligand binding oxidase K00526 E1.17.4.1B; ribonucleoside-diphosphate reductase beta chain [EC:1.17.4.1]
C Others
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: March 29, 2024