+C Peptidases and inhibitors KO
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Peptidases and Inhibitors - Shewanella oneidensis
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AAspartic peptidases
B Family A1: pepsin family
B Family A2: retropepsin family
B Family A5: thermopsin family
B Family A8: signal peptidase II family
C SO_3531 lspA; signal peptidase II LspA K03101 lspA; signal peptidase II [EC:3.4.23.36]
B Family A22: presenilin family
B Family A24: type IV prepilin peptidase family
C SO_0414 pilD; type IV prepilin peptidase PilD K02654 pilD; leader peptidase (prepilin peptidase) / N-methyltransferase [EC:3.4.23.43 2.1.1.-]
B Family A25: gpr protease family
B Family A26: omptin family
B Family A28
B Family A31: HybD endopeptidase family
C SO_2096 hyaD; NiFe hydrogenase maturation protease HyaD K03605 hyaD; hydrogenase maturation protease [EC:3.4.23.-]
B Family A36
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ACysteine peptidases
B Family C1: papain family
B Family C2: calpain family
B Family C3: picornain family
B Family C4: NIa protease family
B Family C5
B Family C9
B Family C10: streptopain family
B Family C11: clostripain family
B Family C12: ubiquitin C-terminal hydrolase family
B Family C13: legumain family
B Family C14: caspase family
B Family C15: pyroglutamyl peptidase I family
B Family C16
B Family C19: ubiquitin-specific protease family
B Family C25: gingipain family
B Family C26: gamma-glutamyl hydrolase family
C SO_3292 guaA; GMP synthase (glutamine-hydrolysing) GuaA K01951 guaA; GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2]
C SO_1267 puuD; gamma-glutamyl-aminobutyrate hydrolase PuuD K07010 K07010; putative glutamine amidotransferase
B Family C27
B Family C30
B Family C37
B Family C39
C SO_A0049 ABC-type bacteriocin export system multifunctional permease/ATPase/protease component K13409 cvaB; ATP-binding cassette, subfamily B, bacterial CvaB/MchF/RaxB
B Family C40
C SO_0061 nlpC; family C40 peptidase lipoprotein NlpC K13695 nlpC; probable lipoprotein NlpC
B Family C44
C SO_3064 purF; amidophosphoribosyltransferase PurF K00764 purF; amidophosphoribosyltransferase [EC:2.4.2.14]
C SO_1325 gltB; NADPH-dependent glutamate synthase large subunit GltB K00265 gltB; glutamate synthase (NADPH) large chain [EC:1.4.1.13]
C SO_4741 glmS; glutamine:fructose-6-phosphate transaminase (isomerizing) GlmS K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C SO_3506 nagB; glucosamine-6-phosphate deaminase NagB K00820 glmS; glutamine---fructose-6-phosphate transaminase (isomerizing) [EC:2.6.1.16]
C SO_3175 wbpQ; asparagine synthase glutamine-hydrolyzing WbpQ K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
C SO_2767 asnB; asparagine synthase glutamine-hydrolyzing AsnB K01953 asnB; asparagine synthase (glutamine-hydrolysing) [EC:6.3.5.4]
B Family C45
B Family C46: hedgehog family
B Family C47: staphopain family
B Family C48: Ulp1 endopeptidase family
B Family C50: separase family
B Family C54: Aut2 peptidase family
B Family C55: YopJ protease family
B Family C56: PfpI endopeptidase family
C SO_1378 peptidase family 56 K05520 yhbO; deglycase [EC:3.5.1.124]
B Family C57: vaccinia virus I7 peptidase family
B Family C58
B Family C59
B Family C60
C SO_2196 srtA; sortase SrtA K07284 srtA; sortase A [EC:3.4.22.70]
B Family C63
B Family C64
B Family C65
B Family C67
B Family C69
B Family C70
B Family C75
B Family C76
B Family C78
B Family C79
B Family C82
C SO_3748 ybiS; LD-transpeptidase YbiS K19235 ybiS; L,D-transpeptidase YbiS
C SO_1899 periplasmic protein with peptidoglycan binding domain K21470 ycbB; L,D-transpeptidase YcbB
C SO_2109 peptidoglycan-binding protein K21470 ycbB; L,D-transpeptidase YcbB
B Family C83
B Family C85
B Family C86
B Family C88
B Family C89
B Family C97
B Family C98
B Family C110
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AGlutamic peptidases
B Family G1
B Family G4
B Family G5: prenyl protease 2 family
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AMetallo peptidases
B Family M1
C SO_1561 cytoplasmic zinc metallopeptidase M1 family K01254 LTA4H; leukotriene-A4 hydrolase [EC:3.3.2.6]
C SO_1997 cold-active zinc metallopeptidase M1 family K01254 LTA4H; leukotriene-A4 hydrolase [EC:3.3.2.6]
C SO_2600 pepN; alanyl aminopeptidase PepN K01256 pepN; aminopeptidase N [EC:3.4.11.2]
C SO_1059 periplasmic alanyl aminopeptidase K01256 pepN; aminopeptidase N [EC:3.4.11.2]
B Family M2
C SO_2494 peptidase family M2 K01283 ACE; peptidyl-dipeptidase A [EC:3.4.15.1]
B Family M3
C SO_4699 prlC; oligopeptidase A PrlC K01414 prlC; oligopeptidase A [EC:3.4.24.70]
C SO_3142 dcp; dipepidyl carboxypeptidase II Dcp K01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5]
C SO_3564 dcp; dipeptidyl carboxypeptidase Dcp K01284 dcp; peptidyl-dipeptidase Dcp [EC:3.4.15.5]
B Family M4: thermolysin family
B Family M5: mycolysin family
B Family M6: immune inhibitor A family
C SO_0130 prtV; extracellular metalloprotease PrtV K09607 ina; immune inhibitor A [EC:3.4.24.-]
B Family M7: snapalysin family
B Family M8: leishmanolysin family
B Family M9
C SO_0639 collagenase K01387 colA; microbial collagenase [EC:3.4.24.3]
B Family M10
B Family M12: astacin/adamalysin family
B Family M13: neprilysin family
C SO_3844 pepO; thermoregulated outer membrane M13 family zinc endopeptidase PepO K07386 pepO; putative endopeptidase [EC:3.4.24.-]
C SO_0491 oligopeptidase lipoprotein M13 family K07386 pepO; putative endopeptidase [EC:3.4.24.-]
C SO_0429 pepO; cell surface zinc endopeptidase PepO K07386 pepO; putative endopeptidase [EC:3.4.24.-]
B Family M14: carboxypeptidase A family
B Family M15: zinc D-Ala-D-Ala carboxypeptidase family
B Family M16: pitrilysin family
C SO_4022 periplasmic peptidase family M16B K07263 pqqL; zinc protease [EC:3.4.24.-]
C SO_3560 predicted non-catalytic member of peptidase subfamily M16B K07263 pqqL; zinc protease [EC:3.4.24.-]
C SO_4811 periplasmic peptidase family M16B K07263 pqqL; zinc protease [EC:3.4.24.-]
B Family M17: leucyl aminopeptidase family
C SO_0959 periplasmic leucyl metal-dependent aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
C SO_1117 cytoplasmic leucyl metal-dependent aminopeptidase K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
C SO_1368 pepA; cytoplasmic leucine metal-dependent aminopeptidase PepA K01255 CARP; leucyl aminopeptidase [EC:3.4.11.1]
C SO_0876 pepB; aminopeptidase PepB K07751 pepB; PepB aminopeptidase [EC:3.4.11.23]
B Family M18
B Family M19: membrane dipeptidase family
B Family M20
C SO_2471 dapE; succinyl-diaminopimelate desuccinylase DapE K01439 dapE; succinyl-diaminopimelate desuccinylase [EC:3.5.1.18]
C SO_1115 pepD; aminoacyl-histidine/glycine-aspartate dipeptidase PepD K01270 pepD; dipeptidase D [EC:3.4.13.-]
B Family M23
C SO_4420 subfamily M23B unassigned peptidase K21472 lytH; peptidoglycan LD-endopeptidase LytH [EC:3.4.-.-]
C SO_2842 subfamily M23B unassigned peptidase K19304 mepM; murein DD-endopeptidase [EC:3.4.24.-]
B Family M24
C SO_1627 map; methionine aminopeptidase Map K01265 map; methionyl aminopeptidase [EC:3.4.11.18]
C SO_0022 pepQ; Xaa-Pro dipeptidase PepQ K01271 pepQ; Xaa-Pro dipeptidase [EC:3.4.13.9]
C SO_1388 ampP; aminopeptidase P AmpP K01262 pepP; Xaa-Pro aminopeptidase [EC:3.4.11.9]
B Family M26
B Family M27
B Family M28: aminopeptidase Y family
B Family M29: aminopeptidase T family
B Family M32: carboxypeptidase Taq family
C SO_1375 thermostable carboxypeptidase 1 K01299 E3.4.17.19; carboxypeptidase Taq [EC:3.4.17.19]
B Family M34: anthrax lethal factor family
B Family M35: deuterolysin family
B Family M36: fungalysin family
B Family M38: beta-aspartyl dipeptidase family
B Family M41: FtsH endopeptidase family
C SO_1197 ftsH; ATP-dependent zinc metalloprotease FtsH K03798 ftsH; cell division protease FtsH [EC:3.4.24.-]
B Family M42: glutamyl aminopeptidase family
B Family M43: cytophagalysin family
B Family M44
B Family M48: Ste24 endopeptidase family
C SO_2728 htpX; Zn-dependent metalloprotease HtpX K03799 htpX; heat shock protein HtpX [EC:3.4.24.-]
C SO_2869 yfgC; periplasmic Zn-dependent protease YfgC K01423 bepA; beta-barrel assembly-enhancing protease [EC:3.4.-.-]
B Family M49: dipeptidyl-peptidase III family
B Family M50: S2P protease family
C SO_1636 rseP; RseA degrading zinc metalloprotease RseP K11749 rseP; regulator of sigma E protease [EC:3.4.24.-]
B Family M54
B Family M55: DppA aminopeptidase family
B Family M56
B Family M67
B Family M72
B Family M73
B Family M74
B Family M80
B Family M82
B Family M85
B Family M88
C SO_0440 ImpA-like cell surface immunomodulating metalloprotease K21429 impA; immunomodulating metalloprotease
B Family M90
C SO_3335 periplasmic protein of unknown function DUF980 K09933 mtfA; MtfA peptidase
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AAsparagine peptide lyases
B Family N1
B Family N8
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AMixed peptidases
B Family P1: DmpA aminopeptidase family
B Family P2
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ASerine peptidases
B Family S1: chymotrypsin family
C SO_3943 degS; serine protease DegS K04691 hhoB; serine protease DegS [EC:3.4.21.-]
B Family S3: togavirin family
B Family S6
B Family S7: flavivirin family
B Family S8: subtilisin family
C SO_3106 sapSH; extracellular serine alkaline protease SapSH K14645 K14645; serine protease [EC:3.4.21.-]
B Family S9: prolyl oligopeptidase family
C SO_2753 prolyl endopeptidase K01322 PREP; prolyl oligopeptidase [EC:3.4.21.26]
C SO_2047 prolyl oligopeptidase family S9 protein K01322 PREP; prolyl oligopeptidase [EC:3.4.21.26]
C SO_3990 dpp4; periplasmic dipeptidylpeptidase IV Dpp4 K01278 DPP4; dipeptidyl-peptidase 4 [EC:3.4.14.5]
C SO_0144 ptrB; oligopeptidase B PtrB K01354 ptrB; oligopeptidase B [EC:3.4.21.83]
B Family S10
B Family S11: D-Ala-D-Ala carboxypeptidase A family
C SO_1164 dacA; D-alanyl-D-alanine carboxypeptidase DacA K07258 dacC; serine-type D-Ala-D-Ala carboxypeptidase (penicillin-binding protein 5/6) [EC:3.4.16.4]
C SO_0999 pbpG; D-alanyl-D-alanine endopeptidase PbpG K07262 pbpG; serine-type D-Ala-D-Ala endopeptidase (penicillin-binding protein 7) [EC:3.4.21.-]
B Family S12: D-Ala-D-Ala carboxypeptidase B family
B Family S13: D-Ala-D-Ala peptidase C family
C SO_2394 dacB; D-alanyl-D-alanine carboxypeptidase DacB K07259 dacB; serine-type D-Ala-D-Ala carboxypeptidase/endopeptidase (penicillin-binding protein 4) [EC:3.4.16.4 3.4.21.-]
B Family S14: ClpP endopeptidase family
C SO_1794 clpP; ATP-dependent Clp protease proteolytic subunit ClpP K01358 clpP; ATP-dependent Clp protease, protease subunit [EC:3.4.21.92]
B Family S15
B Family S16: lon protease family
C SO_1796 lon; ATP-dependent protease La Lon K01338 lon; ATP-dependent Lon protease [EC:3.4.21.53]
B Family S21: assemblin family
B Family S24: LexA family
C SO_4603 lexA; bifunctional transcriptional repressor of SOS-response/self-cleaving protease LexA K01356 lexA; repressor LexA [EC:3.4.21.88]
C SO_A0013 umuD; DNA polymerase V subunit UmuD K03503 umuD; DNA polymerase V [EC:3.4.21.-]
B Family S26: signal peptidase I family
C SO_1347 lepB; signal peptidase I LepB K03100 lepB; signal peptidase I [EC:3.4.21.89]
C SO_2924 signal peptidase I K03100 lepB; signal peptidase I [EC:3.4.21.89]
B Family S28
B Family S31
B Family S32
B Family S33
C SO_4400 prolyl aminopeptidase S33 family K01259 pip; proline iminopeptidase [EC:3.4.11.5]
B Family S41: C-terminal processing peptidase family
C SO_0047 periplasmic C-terminal peptidase S41 family K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
C SO_2601 prc; periplasmic C-terminal processing protease Prc K03797 E3.4.21.102; carboxyl-terminal processing protease [EC:3.4.21.102]
C SO_3411 predicted non-catalytic member of peptidase subfamily S41B K08676 tri; tricorn protease [EC:3.4.21.-]
B Family S45
B Family S49: protease IV family
C SO_2420 sppA; signal peptide peptidase SppA K04773 sppA; protease IV [EC:3.4.21.-]
C SO_2933 sohB; inner membrane anchored endopeptidase SohB K04774 sohB; serine protease SohB [EC:3.4.21.-]
B Family S50
B Family S51
C SO_2730 pepE; dipeptidase E PepE K05995 pepE; dipeptidase E [EC:3.4.13.21]
B Family S53
B Family S54: Rhomboid family
C SO_4671 glpG; intramembrane protease rhomboid family GlpG K02441 glpG; rhomboid protease GlpG [EC:3.4.21.105]
B Family S55: SpoIVB peptidase family
B Family S62
B Family S66
B Family S77: phage prohead processing peptidase family
B Family S78
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AThreonine peptidases
B Family T1: proteasome family
C SO_4162 hslV; HlsVU protease peptidase component HslV K01419 hslV; ATP-dependent HslUV protease, peptidase subunit HslV [EC:3.4.25.2]
B Family T2
C SO_2115 iaaA; bifunctional isoaspartyl dipeptidase / l-asparaginase IaaA K13051 ASRGL1; L-asparaginase / beta-aspartyl-peptidase [EC:3.5.1.1 3.4.19.5]
B Family T3: gamma-glutamyltransferase family
C SO_1952 ggtA; gamma-glutamyltransferase GgtA K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
C SO_0741 ggtB; gamma-glutamyltransferase GgtB K00681 ggt; gamma-glutamyltranspeptidase / glutathione hydrolase [EC:2.3.2.2 3.4.19.13]
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APeptidases of unknown catalytic type
B Family U32
C SO_1252 yegQ; peptidase U32 family YegQ K08303 prtC; U32 family peptidase [EC:3.4.-.-]
C SO_3797 ydcP; peptidase U32 family YdcP K24847 rlhA; 23S rRNA 5-hydroxycytidine C2501 synthase
C SO_1248 peptidase U32 family YhbV K24845 ubiV; O2-independent ubiquinone biosynthesis protein UbiV
C SO_1249 peptidase U32 family YhbU K24844 ubiU; O2-independent ubiquinone biosynthesis protein UbiU
B Family U62
C SO_4078 tldE; microcin-processing peptidase TldE K03592 pmbA; PmbA protein
C SO_4091 tldD; microcin-processing peptidase 2 TldD K03568 tldD; TldD protein
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APeptidase inhibitors
B Family I1: Kazal family
B Family I2: Kunitz - BPTI family
B Family I4: serpin family
B Family I11: ecotin family
C SO_2312 ecoT; serine protease inhibitor ecotin EcoT K08276 eco; ecotin
B Family I17: WAP-type family
B Family I25: cystatin family
B Family I27: calpastatin family
B Family I32: IAP family
B Family I34: IA3 family
B Family I35: timp family
B Family I39: alpha2M family
C SO_0066 YfhM family alpha2-macroglobulin K06894 yfhM; alpha-2-macroglobulin
B Family I47: latexin family
B Family I49: proSAAS family
B Family I51: IC family
B Family I57: staphostatin B family
B Family I63
B Family I80
B Family I87
C SO_0606 hflC; membrane anchored FtsH modulator component 2 HflC K04087 hflC; modulator of FtsH protease HflC
C SO_0605 hflK; membrane anchored FtsH modulator component 1 HflK K04088 hflK; modulator of FtsH protease HflK
B Family I93
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 13, 2023
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Classification taken and modified from MEROPS