+C Two-component system KO
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Two-Component System - Sphingomonas hengshuiensis
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AOmpR family
B PhoR-PhoB (phosphate starvation response)
C TS85_13910 ATPase K07636 phoR; two-component system, OmpR family, phosphate regulon sensor histidine kinase PhoR [EC:2.7.13.3]
C TS85_13940 chemotaxis protein CheY K07657 phoB; two-component system, OmpR family, phosphate regulon response regulator PhoB
B SenX3-RegX3 (phosphate starvation response)
B PhoQ-PhoP (magnesium transport)
B EnvZ-OmpR (osmotic stress response)
B RstB-RstA
B CpxA-CpxR (envelope stress response)
B CssS-CssR (secretion stress response)
B CreC-CreB (phosphate regulation)
B BaeS-BaeR (envelope stress response)
B BasS-BasR (antimicrobial peptide resistance)
B CusS-CusR (copper tolerance)
B QseC-QseB (quorum sensing)
B KdpD-KdpE (potassium transport)
C TS85_00375 histidine kinase K07646 kdpD; two-component system, OmpR family, sensor histidine kinase KdpD [EC:2.7.13.3]
C TS85_00380 Fis family transcriptional regulator K07667 kdpE; two-component system, OmpR family, KDP operon response regulator KdpE
B TorS-TorR (TMAO respiration)
B ArcB-ArcA (anoxic redox control)
B TctE-TctD (tricarboxylic acid transport)
B ResE-ResD (aerobic and anaerobic respiration)
B VicK-VicR (cell wall metabolism)
B MprB-MprA (maintenance of persistent infection)
B MtrB-MtrA (osmotic stress response)
B PrrB-PrrA (intracellular multiplication)
B TrcS-TrcR
B NrsS-NrsR (nickel tolerance)
B ManS-ManR (manganese homeostasis)
B NblS-NblR (photosynthesis)
B SasA-RpaAB (circadian timing mediating)
B SaeS-SaeR (staphylococcal virulence regulation)
B BceS-BceR (bacitracin transport)
B BraS-BraR (bacitracin transport)
B GraS-GraR (cationic antimicrobial peptide transport)
B YxdK-YxdJ (antimicrobial peptide response)
B ChvG-ChvI (acidity sensing)
C TS85_06210 histidine kinase K14980 chvG; two-component system, OmpR family, sensor histidine kinase ChvG [EC:2.7.13.3]
C TS85_04990 hypothetical protein K14980 chvG; two-component system, OmpR family, sensor histidine kinase ChvG [EC:2.7.13.3]
C TS85_06215 transcriptional regulator K14981 chvI; two-component system, OmpR family, response regulator ChvI
B CiaH-CiaR
B ParS-ParR (polymyxin-adaptive resistance)
B AdeS-AdeR
B VanS-VanR (VanB type vancomycin resistance)
B VanS-VanR (VanE type vancomycin resistance)
B VanS-VanR (actinomycete type vancomycin resistance)
B ArlS-ArlR (virulence regulation)
B Ihk-Irr (virulence regulation)
B PfeS-PfeR (enterobactin-dependent iron acquisition)
B NisK-NisR (lantibiotic biosynthesis)
B Unclassified
C TS85_13665 histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C TS85_00390 histidine kinase K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C TS85_10300 hypothetical protein K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
C TS85_18540 transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
C TS85_00385 transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
C TS85_10305 transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
C TS85_09090 chemotaxis protein CheY K02483 K02483; two-component system, OmpR family, response regulator
C TS85_13660 transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
C TS85_04995 chemotaxis protein CheY K02483 K02483; two-component system, OmpR family, response regulator
C TS85_09545 hypothetical protein K02483 K02483; two-component system, OmpR family, response regulator
C TS85_15275 XRE family transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
C TS85_21330 transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
C TS85_03580 transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
C TS85_16570 PhoB family transcriptional regulator K02483 K02483; two-component system, OmpR family, response regulator
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ANarL family
B NarX-NarL (nitrate respiration)
B NarQ-NarP (nitrate respiration)
B UhpB-UhpA (hexose phosphates uptake)
B FusK-FusR (virulence regulation)
B RcsC-RcsD-RcsB (capsule synthesis)
B BarA-UvrY (central carbon metabolism)
B ComP-ComA (competence)
B EvgS-EvgA (acid and drug tolerance)
B DegS-DegU (multicellular behavior control)
B DesK-DesR (membrane lipid fluidity regulation)
B VraS-VraR (cell-wall peptidoglycan synthesis)
B LiaS-LiaR (cell wall stress response)
B DevS-DevR (redox response)
B NreB-NreC (dissimilatory nitrate/nitrite reduction)
B YdfH-YdfI
B SalK-SalR
B PprA–PprB (biofilm formation)
B Unclassified
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ASpo family
B KinABCDE-Spo0FA (sporulation control)
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ACitB family
B CitA-CitB (citrate fermentation)
B CitS-CitT (magnesium-citrate transport)
B DcuS-DcuR (C4-dicarboxylate metabolism)
B DctS-DctR (C4-dicarboxylate transport)
B MalK-MalR (malate transport)
B Unclassified
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ALytTR family
B LysS-LysR
B AlgZ-AlgR (alginate production)
B NatK-NatR (sodium extrusion)
B AgrC-AgrA (exoprotein synthesis)
B AgrC2-AgrA2 (virulence regulation)
B ComD-ComE (competence)
B Unclassified
C TS85_04450 hypothetical protein K02478 K02478; two-component system, LytTR family, sensor kinase [EC:2.7.13.3]
C TS85_10290 hypothetical protein K02477 K02477; two-component system, LytTR family, response regulator
C TS85_04445 LytTR family transcriptional regulator K02477 K02477; two-component system, LytTR family, response regulator
C TS85_23310 chemotaxis protein CheY K02477 K02477; two-component system, LytTR family, response regulator
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ANtrC family
B GlnL-GlnG (nitrogen regulation)
C TS85_07330 histidine kinase K07708 glnL; two-component system, NtrC family, nitrogen regulation sensor histidine kinase GlnL [EC:2.7.13.3]
C TS85_07335 chemotaxis protein CheY K07712 glnG; two-component system, NtrC family, nitrogen regulation response regulator GlnG
B NtrY-NtrX (nitrogen regulation)
C TS85_07345 ATPase AAA K13599 ntrX; two-component system, NtrC family, nitrogen regulation response regulator NtrX
B HydH-HydG (metal tolerance)
C TS85_11055 RNA polymerase subunit sigma-54 K07713 zraR; two-component system, NtrC family, response regulator HydG
B AtoS-AtoC (cPHB biosynthesis)
B PilS-PilR (type 4 fimbriae synthesis)
B GlrK-GlrR (amino sugar metabolism)
B PgtB-PgtA (phosphoglycerate transport)
B DctB-DctD (C4-dicarboxylate transport)
B KinB-AlgB (alginate production)
B HupT-HupR (hydrogenase synthesis regulation)
B Unclassified
C TS85_21365 Fis family transcriptional regulator K02481 flgR; two-component system, NtrC family, response regulator
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ACheA family
B CheA-CheYBV (chemotaxis)
C TS85_09530 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C TS85_10905 chemotaxis protein CheA K03407 cheA; two-component system, chemotaxis family, sensor kinase CheA [EC:2.7.13.3]
C TS85_09520 chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C TS85_10900 Fis family transcriptional regulator K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C TS85_10925 chemotaxis protein CheY K03413 cheY; two-component system, chemotaxis family, chemotaxis protein CheY
C TS85_09515 chemotaxis protein CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C TS85_08165 chemotaxis protein CheB K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
C TS85_10920 chemotaxis protein K03412 cheB; two-component system, chemotaxis family, protein-glutamate methylesterase/glutaminase [EC:3.1.1.61 3.5.1.44]
B ChpA-ChpB/PilGH (chemosensory)
B PixL-PixGH (positive phototaxis)
B WspE-WspRF (chemosensory)
B Cph1-Rcp1 (light response)
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ACell cycle family
B PleC-PleD (cell fate control)
C TS85_01905 chemotaxis protein CheY K11443 divK; two-component system, cell cycle response regulator DivK
B CckA-CtrA/CpdR (cell cycle control)
C TS85_07060 histidine kinase K13587 cckA; two-component system, cell cycle sensor histidine kinase and response regulator CckA [EC:2.7.13.3]
C TS85_15555 chemotaxis protein CheY K13584 ctrA; two-component system, cell cycle response regulator CtrA
C TS85_15915 response regulator K13589 cpdR; two-component system, cell cycle response regulator CpdR
B Hk1-Rrp1 (glycerol uptake and utilization)
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ALux family
B LuxQN/CqsS-LuxU-LuxO (quorum sensing)
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ALuxR family
B DctS-DctR (C4-dicarboxylate transport)
B TtrS-TtrR (tetrathionate respiration)
B FixL-FixJ (nitrogen fixation)
C TS85_16445 hypothetical protein K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3]
C TS85_10850 hypothetical protein K14986 fixL; two-component system, LuxR family, sensor kinase FixL [EC:2.7.13.3]
C TS85_16450 fixJ; response regulator FixJ K14987 fixJ; two-component system, LuxR family, response regulator FixJ
C TS85_10855 fixJ; response regulator FixJ K14987 fixJ; two-component system, LuxR family, response regulator FixJ
B SsrA-SsrB
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AOther families
B FlrB-FlrC (polar flagellar synthesis)
C TS85_19535 Fis family transcriptional regulator K10943 flrC; two-component system, response regulator FlrC
B AauS-AauR (acidic amino acids utilization)
B SLN1-YPD1-SSK1/SKN7 (osmosensing)
B RpfC-RpfG (cell-to-cell signaling)
B GlnK-GlnL (glutamine utilization)
B HspS-HspR (hexose phosphates uptake)
B YesM-YesN
B CikA
B RegB-RegA (redox response)
C TS85_00265 histidine kinase K15011 regB; two-component system, sensor histidine kinase RegB [EC:2.7.13.3]
C TS85_00260 chemotaxis protein CheY K15012 regA; two-component system, response regulator RegA
B FitF-FitH (insecticidal toxin regulation)
B PhcS-PhcRQ
B SagS-HptB-HsbR (swarming activity and biofilm formation)
C TS85_14695 histidine phosphotransferase K20976 hptB; histidine phosphotransfer protein HptB
B PdtaS-PdtaR
C TS85_18040 hypothetical protein K00936 pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3]
C TS85_09915 histidine kinase K00936 pdtaS; two-component system, sensor histidine kinase PdtaS [EC:2.7.13.3]
B NasS-NasT
C TS85_18635 nitrate transporter K22067 nasS; two-component system, oxyanion-binding sensor
C TS85_18640 chemotaxis protein CheY K07183 nasT; two-component system, response regulator / RNA-binding antiterminator
B Unclassified
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: December 14, 2023