+E Replication protein KO
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DNA Replication Proteins - Tuber melanosporum
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
D GSTUM_00005229001 hypothetical protein K02604 ORC2; origin recognition complex subunit 2
D GSTUM_00008768001 hypothetical protein K02605 ORC3; origin recognition complex subunit 3
D GSTUM_00010806001 hypothetical protein K02606 ORC4; origin recognition complex subunit 4
D GSTUM_00009336001 hypothetical protein K02607 ORC5; origin recognition complex subunit 5
D GSTUM_00011618001 hypothetical protein K02608 ORC6; origin recognition complex subunit 6
D GSTUM_00005326001 hypothetical protein K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
D GSTUM_00005881001 hypothetical protein K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D GSTUM_00006910001 hypothetical protein K02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]
D GSTUM_00003837001 hypothetical protein K02209 MCM5; DNA replication licensing factor MCM5 [EC:5.6.2.3]
D GSTUM_00010054001 hypothetical protein K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
D GSTUM_00004110001 hypothetical protein K02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]
C CDK (cyclin dependent kinase)
C DDK (Dbf-4 dependent kinase)
D GSTUM_00000259001 hypothetical protein K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
D GSTUM_00000807001 hypothetical protein K02309 DBF4; regulatory subunit for Cdc7p protein kinase
C GINS complex
D GSTUM_00000586001 hypothetical protein K10732 GINS1; GINS complex subunit 1
D GSTUM_00010810001 hypothetical protein K10733 GINS2; GINS complex subunit 2
D GSTUM_00010919001 hypothetical protein K10734 GINS3; GINS complex subunit 3
D GSTUM_00002524001 hypothetical protein K10735 GINS4; GINS complex subunit 4
C Other initiation factors
D GSTUM_00007687001 hypothetical protein K03507 DPB11; DNA replication regulator DPB11
D GSTUM_00009059001 hypothetical protein K06628 CDC45; cell division control protein 45
D GSTUM_00000964001 hypothetical protein K10736 MCM10; minichromosome maintenance protein 10
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
D GSTUM_00004441001 hypothetical protein K02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
D GSTUM_00007656001 hypothetical protein K02321 POLA2; DNA polymerase alpha subunit B
D GSTUM_00008006001 hypothetical protein K02684 PRI1; DNA primase small subunit [EC:2.7.7.102]
D GSTUM_00010447001 hypothetical protein K02685 PRI2; DNA primase large subunit
C DNA polymerase epsilon complex
D GSTUM_00007495001 hypothetical protein K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
D GSTUM_00010342001 hypothetical protein K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
D GSTUM_00002379001 hypothetical protein K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
C DNA polymerase delta complex
D GSTUM_00008021001 hypothetical protein K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
D GSTUM_00008900001 hypothetical protein K02328 POLD2; DNA polymerase delta subunit 2
D GSTUM_00002952001 hypothetical protein K03504 POLD3; DNA polymerase delta subunit 3
D GSTUM_00009250001 hypothetical protein K03504 POLD3; DNA polymerase delta subunit 3
C DNA polymerase gamma complex (mitochondrial)
D GSTUM_00007666001 hypothetical protein K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
C RPA (replication protein A)
D GSTUM_00005528001 hypothetical protein K07466 RFA1; replication factor A1
D GSTUM_00003154001 hypothetical protein K10739 RFA2; replication factor A2
C RFC (replication factor C)
D GSTUM_00009792001 hypothetical protein K10754 RFC1; replication factor C subunit 1
D GSTUM_00007494001 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
D GSTUM_00008699001 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
D GSTUM_00009072001 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
D GSTUM_00002351001 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
C RNase H
D GSTUM_00007397001 hypothetical protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D GSTUM_00009401001 hypothetical protein K10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
D GSTUM_00003158001 hypothetical protein K10745 RNASEH2C; ribonuclease H2 subunit C
C Other elongation factors
D GSTUM_00007106001 hypothetical protein K04802 PCNA; proliferating cell nuclear antigen
D GSTUM_00002391001 hypothetical protein K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D GSTUM_00011641001 hypothetical protein K19783 HCS1; DNA polymerase alpha-associated DNA helicase A [EC:5.6.2.3]
D GSTUM_00000275001 hypothetical protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
D GSTUM_00009088001 hypothetical protein K10746 EXO1; exonuclease 1 [EC:3.1.-.-]
D GSTUM_00005992001 hypothetical protein K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DNA Replication Termination Factors
C DNA methylation enzymes
D GSTUM_00003328001 hypothetical protein K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D GSTUM_00012206001 hypothetical protein K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
C Prevention of re-replication factors
C Telomere proteins
D Shelterin complex
E GSTUM_00010501001 hypothetical protein K11109 POT1; protection of telomeres protein 1
D TERB1-TERB2-MAJIN complex
D CST complex (animals)
D CST complex (yeast)
D RIF proteins
D SIR proteins
C Telomerase complex (animals)
D GSTUM_00011041001 hypothetical protein K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Dyskerin complex
E GSTUM_00009086001 hypothetical protein K11128 GAR1; H/ACA ribonucleoprotein complex subunit 1
E GSTUM_00011136001 ribosome biogenesis protein Nhp2 K11129 NHP2; H/ACA ribonucleoprotein complex subunit 2
E GSTUM_00003046001 hypothetical protein K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
E GSTUM_00009737001 hypothetical protein K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
C Telomerase complex (fungi)
D GSTUM_00011041001 hypothetical protein K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Sm core complex
E GSTUM_00001865001 hypothetical protein K11096 SNRPD2; small nuclear ribonucleoprotein D2
E GSTUM_00009442001 hypothetical protein K11088 SNRPD3; small nuclear ribonucleoprotein D3
E GSTUM_00000050001 hypothetical protein K11097 SNRPE; small nuclear ribonucleoprotein E
E GSTUM_00003354001 hypothetical protein K11098 SNRPF; small nuclear ribonucleoprotein F
E GSTUM_00008735001 hypothetical protein K11099 SNRPG; small nuclear ribonucleoprotein G
C ELG1-RFC complex
D GSTUM_00007494001 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
D GSTUM_00008699001 hypothetical protein K10755 RFC2_4; replication factor C subunit 2/4
D GSTUM_00009072001 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
D GSTUM_00002351001 hypothetical protein K10756 RFC3_5; replication factor C subunit 3/5
C MRN complex
D GSTUM_00004321001 hypothetical protein K10865 MRE11; double-strand break repair protein MRE11
D GSTUM_00001634001 hypothetical protein K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
C Other termination factors
D GSTUM_00007669001 hypothetical protein K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D GSTUM_00012213001 hypothetical protein K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D GSTUM_00005329001 hypothetical protein K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D GSTUM_00001478001 hypothetical protein K11135 PINX1; Pin2-interacting protein X1
D GSTUM_00009456001 hypothetical protein K11137 TELO2; telomere length regulation protein
D GSTUM_00001117001 hypothetical protein K23314 WRAP53; telomerase Cajal body protein 1
D GSTUM_00011111001 hypothetical protein K25059 SDE2; replication stress response regulator SDE2
D GSTUM_00005282001 hypothetical protein K25186 RTF2; replication termination factor 2
D GSTUM_00010922001 hypothetical protein K22485 TBF1; protein TBF1
B DNA Topoisomerases
C GSTUM_00008425001 hypothetical protein K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C GSTUM_00006716001 hypothetical protein K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C GSTUM_00005673001 hypothetical protein K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
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AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
D RNase H
E GSTUM_00007397001 hypothetical protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D Other elongation factors
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E GSTUM_00007397001 hypothetical protein K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
E GSTUM_00002391001 hypothetical protein K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
E GSTUM_00000275001 hypothetical protein K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
E GSTUM_00005992001 hypothetical protein K10747 LIG1; DNA ligase 1 [EC:6.5.1.1 6.5.1.6 6.5.1.7]
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
C Prevention of re-replication factors
B DNA Topoisomerases
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022