+E Replication protein KO
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DNA Replication Proteins - Tetraodon nigroviridis (spotted green pufferfish)
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AEukaryotic type
B DNA Replication Initiation Factors
C pre-RC (pre-replication complex)
D GSTEN00010045G001 unnamed protein product K02603 ORC1; origin recognition complex subunit 1
D GSTEN00015101G001 unnamed protein product K02604 ORC2; origin recognition complex subunit 2
D GSTEN00001229G001 unnamed protein product K02605 ORC3; origin recognition complex subunit 3
D GSTEN00032136G001 unnamed protein product K02605 ORC3; origin recognition complex subunit 3
D GSTEN00005266G001 unnamed protein product K02606 ORC4; origin recognition complex subunit 4
D GSTEN00004097G001 unnamed protein product K02607 ORC5; origin recognition complex subunit 5
D GSTEN00006375G001 unnamed protein product K10727 CDT1; chromatin licensing and DNA replication factor 1
D GSTEN00011951G001 unnamed protein product K02213 CDC6; cell division control protein 6
D GSTEN00032473G001 unnamed protein product K02540 MCM2; DNA replication licensing factor MCM2 [EC:5.6.2.3]
D GSTEN00035496G001 unnamed protein product K02541 MCM3; DNA replication licensing factor MCM3 [EC:5.6.2.3]
D GSTEN00016183G001 unnamed protein product K02212 MCM4; DNA replication licensing factor MCM4 [EC:5.6.2.3]
D GSTEN00015093G001 unnamed protein product K02542 MCM6; DNA replication licensing factor MCM6 [EC:5.6.2.3]
D GSTEN00029242G001 unnamed protein product K02210 MCM7; DNA replication licensing factor MCM7 [EC:5.6.2.3]
C CDK (cyclin dependent kinase)
D GSTEN00018864G001 unnamed protein product K06627 CCNA; cyclin-A
D GSTEN00024450G001 unnamed protein product K06627 CCNA; cyclin-A
D GSTEN00024300G001 unnamed protein product K06626 CCNE; G1/S-specific cyclin-E1
D GSTEN00011727G001 unnamed protein product K06626 CCNE; G1/S-specific cyclin-E1
D GSTEN00033829G001 unnamed protein product K02206 CDK2; cyclin-dependent kinase 2 [EC:2.7.11.22]
C DDK (Dbf-4 dependent kinase)
D GSTEN00013380G001 unnamed protein product K02214 CDC7; cell division control protein 7 [EC:2.7.11.1]
C GINS complex
D GSTEN00025006G001 unnamed protein product K10732 GINS1; GINS complex subunit 1
D GSTEN00017646G001 unnamed protein product K10733 GINS2; GINS complex subunit 2
D GSTEN00008499G001 unnamed protein product K10734 GINS3; GINS complex subunit 3
D GSTEN00011925G001 unnamed protein product K10735 GINS4; GINS complex subunit 4
C Other initiation factors
D GSTEN00025565G001 unnamed protein product K10728 TOPBP1; topoisomerase (DNA) II binding protein 1
D GSTEN00032550G001 unnamed protein product K10730 RECQL4; ATP-dependent DNA helicase Q4 [EC:5.6.2.4]
D GSTEN00029587G001 unnamed protein product K06628 CDC45; cell division control protein 45
D GSTEN00018739G001 unnamed protein product K10737 MCM8; DNA helicase MCM8 [EC:5.6.2.4]
D GSTEN00013950G001 unnamed protein product K10738 MCM9; DNA helicase MCM9 [EC:5.6.2.4]
D GSTEN00013259G001 unnamed protein product K10736 MCM10; minichromosome maintenance protein 10
D GSTEN00003585G001 unnamed protein product K26052 CINP; cyclin-dependent kinase 2-interacting protein
D GSTEN00018295G001 unnamed protein product K26116 MTBP; Mdm2-binding protein
D GSTEN00019675G001 unnamed protein product K26117 TICRR; Treslin
B DNA Replication Elongation Factors
C DNA polymerase alpha / primase complex
D GSTEN00015518G001 unnamed protein product K02320 POLA1; DNA polymerase alpha subunit A [EC:2.7.7.7]
D GSTEN00031153G001 unnamed protein product K02321 POLA2; DNA polymerase alpha subunit B
D GSTEN00030696G001 unnamed protein product K02685 PRI2; DNA primase large subunit
C DNA polymerase epsilon complex
D GSTEN00029542G001 unnamed protein product K02324 POLE; DNA polymerase epsilon subunit 1 [EC:2.7.7.7]
D GSTEN00032040G001 unnamed protein product K02325 POLE2; DNA polymerase epsilon subunit 2 [EC:2.7.7.7]
D GSTEN00005214G001 unnamed protein product K02326 POLE3; DNA polymerase epsilon subunit 3 [EC:2.7.7.7]
D GSTEN00028806G001 unnamed protein product K03506 POLE4; DNA polymerase epsilon subunit 4 [EC:2.7.7.7]
C DNA polymerase delta complex
D GSTEN00021892G001 unnamed protein product K02327 POLD1; DNA polymerase delta subunit 1 [EC:2.7.7.7]
D GSTEN00004530G001 unnamed protein product K02328 POLD2; DNA polymerase delta subunit 2
D GSTEN00015201G001 unnamed protein product K03504 POLD3; DNA polymerase delta subunit 3
C DNA polymerase gamma complex (mitochondrial)
D GSTEN00022827G001 unnamed protein product K02332 POLG; DNA polymerase gamma 1 [EC:2.7.7.7]
D GSTEN00032508G001 unnamed protein product K02333 POLG2; DNA polymerase gamma 2
C RPA (replication protein A)
D GSTEN00029998G001 unnamed protein product K07466 RFA1; replication factor A1
D GSTEN00005543G001 unnamed protein product K10739 RFA2; replication factor A2
C RFC (replication factor C)
D GSTEN00010189G001 unnamed protein product K10754 RFC1; replication factor C subunit 1
D GSTEN00001491G001 unnamed protein product K10755 RFC2_4; replication factor C subunit 2/4
D GSTEN00027867G001 unnamed protein product K10755 RFC2_4; replication factor C subunit 2/4
D GSTEN00019812G001 unnamed protein product K10755 RFC2_4; replication factor C subunit 2/4
D GSTEN00018858G001 unnamed protein product K10756 RFC3_5; replication factor C subunit 3/5
D GSTEN00029055G001 unnamed protein product K10756 RFC3_5; replication factor C subunit 3/5
C RNase H
D GSTEN00020247G001 unnamed protein product K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D GSTEN00007880G001 unnamed protein product K10743 RNASEH2A; ribonuclease H2 subunit A [EC:3.1.26.4]
D GSTEN00025920G001 unnamed protein product K10744 RNASEH2B; ribonuclease H2 subunit B
C Other elongation factors
D GSTEN00028590G001 unnamed protein product K04802 PCNA; proliferating cell nuclear antigen
D GSTEN00025786G001 unnamed protein product K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
D GSTEN00004156G001 unnamed protein product K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
B DNA Replication Termination Factors
C DNA methylation enzymes
D GSTEN00034384G001 unnamed protein product K00558 DNMT1; DNA (cytosine-5)-methyltransferase 1 [EC:2.1.1.37]
D GSTEN00035426G001 unnamed protein product K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
D GSTEN00035725G001 unnamed protein product K17398 DNMT3A; DNA (cytosine-5)-methyltransferase 3A [EC:2.1.1.37]
D GSTEN00013108G001 unnamed protein product K17399 DNMT3B; DNA (cytosine-5)-methyltransferase 3B [EC:2.1.1.37]
C Prevention of re-replication factors
D GSTEN00033012G001 unnamed protein product K10749 GMNN; geminin
D GSTEN00009252G001 unnamed protein product K05868 CCNB1; G2/mitotic-specific cyclin-B1
D GSTEN00008349G001 unnamed protein product K21770 CCNB2; G2/mitotic-specific cyclin-B2
D GSTEN00034481G001 unnamed protein product K21771 CCNB3; G2/mitotic-specific cyclin-B3
D GSTEN00005314G001 unnamed protein product K21777 CCNB; G2/mitotic-specific cyclin-B, other
D GSTEN00004705G001 unnamed protein product K02087 CDK1; cyclin-dependent kinase 1 [EC:2.7.11.22 2.7.11.23]
C Telomere proteins
D Shelterin complex
E GSTEN00019696G001 unnamed protein product K11109 POT1; protection of telomeres protein 1
E GSTEN00027584G001 unnamed protein product K11113 TERF2IP; telomeric repeat-binding factor 2-interacting protein 1
D TERB1-TERB2-MAJIN complex
E GSTEN00033331G001 unnamed protein product K25749 TERB1; telomere repeats-binding bouquet formation protein 1
D CST complex (animals)
E GSTEN00026426G001 unnamed protein product K23312 STN1; CST complex subunit STN1
D CST complex (yeast)
D RIF proteins
D SIR proteins
C Telomerase complex (animals)
D GSTEN00029988G001 unnamed protein product K11124 SMG6; protein SMG6 [EC:3.1.-.-]
D GSTEN00019522G001 unnamed protein product K11125 SMG5; protein SMG5
D GSTEN00017552G001 unnamed protein product K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Dyskerin complex
E GSTEN00024392G001 unnamed protein product K11128 GAR1; H/ACA ribonucleoprotein complex subunit 1
E GSTEN00007057G001 unnamed protein product K11129 NHP2; H/ACA ribonucleoprotein complex subunit 2
E GSTEN00005706G001 unnamed protein product K11130 NOP10; H/ACA ribonucleoprotein complex subunit 3
E GSTEN00003584G001 unnamed protein product K11131 DKC1; H/ACA ribonucleoprotein complex subunit 4 [EC:5.4.99.-]
C Telomerase complex (fungi)
D GSTEN00017552G001 unnamed protein product K11126 TERT; telomerase reverse transcriptase [EC:2.7.7.49]
D Sm core complex
E GSTEN00022086G001 unnamed protein product K11096 SNRPD2; small nuclear ribonucleoprotein D2
E GSTEN00009546G001 unnamed protein product K11088 SNRPD3; small nuclear ribonucleoprotein D3
E GSTEN00014161G001 unnamed protein product K11097 SNRPE; small nuclear ribonucleoprotein E
E GSTEN00023807G001 unnamed protein product K11098 SNRPF; small nuclear ribonucleoprotein F
E GSTEN00005345G001 unnamed protein product K11099 SNRPG; small nuclear ribonucleoprotein G
C ELG1-RFC complex
D GSTEN00001491G001 unnamed protein product K10755 RFC2_4; replication factor C subunit 2/4
D GSTEN00027867G001 unnamed protein product K10755 RFC2_4; replication factor C subunit 2/4
D GSTEN00019812G001 unnamed protein product K10755 RFC2_4; replication factor C subunit 2/4
D GSTEN00018858G001 unnamed protein product K10756 RFC3_5; replication factor C subunit 3/5
D GSTEN00029055G001 unnamed protein product K10756 RFC3_5; replication factor C subunit 3/5
C MRN complex
D GSTEN00014855G001 unnamed protein product K10865 MRE11; double-strand break repair protein MRE11
D GSTEN00033782G001 unnamed protein product K10866 RAD50; DNA repair protein RAD50 [EC:3.6.-.-]
D GSTEN00033989G001 unnamed protein product K10867 NBN; nibrin
C Other termination factors
D GSTEN00005388G001 unnamed protein product K04728 ATM; serine-protein kinase ATM [EC:2.7.11.1]
D GSTEN00013955G001 unnamed protein product K06642 PRKDC; DNA-dependent protein kinase catalytic subunit [EC:2.7.11.1]
D GSTEN00024209G001 unnamed protein product K10848 ERCC4; DNA excision repair protein ERCC-4 [EC:3.1.-.-]
D GSTEN00030380G001 unnamed protein product K24070 PARP1; poly [ADP-ribose] polymerase 1 [EC:2.4.2.30]
D GSTEN00029135G001 unnamed protein product K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D GSTEN00007062G001 unnamed protein product K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D GSTEN00027301G001 unnamed protein product K10798 PARP2_3_4; poly [ADP-ribose] polymerase 2/3/4 [EC:2.4.2.30]
D GSTEN00034904G001 unnamed protein product K10799 TNKS; tankyrase [EC:2.4.2.30]
D GSTEN00024768G001 unnamed protein product K10799 TNKS; tankyrase [EC:2.4.2.30]
D GSTEN00030290G001 unnamed protein product K11135 PINX1; Pin2-interacting protein X1
D GSTEN00005897G001 unnamed protein product K11136 RTEL1; regulator of telomere elongation helicase 1 [EC:5.6.2.3]
D GSTEN00024050G001 unnamed protein product K11137 TELO2; telomere length regulation protein
D GSTEN00008524G001 unnamed protein product K01149 TRIR; telomerase RNA component interacting RNase [EC:3.1.13.-]
D GSTEN00013401G001 unnamed protein product K15255 PIF1; ATP-dependent DNA helicase PIF1 [EC:5.6.2.3]
D GSTEN00019003G001 unnamed protein product K21772 PURA; transcriptional activator protein Pur-alpha
D GSTEN00008061G001 unnamed protein product K21772 PURA; transcriptional activator protein Pur-alpha
D GSTEN00009013G001 unnamed protein product K21800 PURG; purine-rich element-binding protein gamma
D GSTEN00006998G001 unnamed protein product K23314 WRAP53; telomerase Cajal body protein 1
D GSTEN00008130G001 unnamed protein product K25186 RTF2; replication termination factor 2
B DNA Topoisomerases
C GSTEN00006211G001 unnamed protein product K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C GSTEN00014052G001 unnamed protein product K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C GSTEN00016753G001 unnamed protein product K03163 TOP1; DNA topoisomerase I [EC:5.6.2.1]
C GSTEN00033707G001 unnamed protein product K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C GSTEN00024101G001 unnamed protein product K03164 TOP2; DNA topoisomerase II [EC:5.6.2.2]
C GSTEN00009201G001 unnamed protein product K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
C GSTEN00011897G001 unnamed protein product K03165 TOP3; DNA topoisomerase III [EC:5.6.2.1]
#
AProkaryotic type
B DNA Replication Initiation Factors
C Initiation factors (bacterial)
C Initiation factors (archaeal)
B DNA Replication Elongation Factors
C Elongation factors (bacterial)
D DNA polymerase III holoenzyme
D RNase H
E GSTEN00020247G001 unnamed protein product K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D Other elongation factors
C Elongation factors (archaeal)
D B-family DNA polymerases
D D-family DNA polymerases
D RNase H
E GSTEN00020247G001 unnamed protein product K03469 rnhA; ribonuclease HI [EC:3.1.26.4]
D RFC (replication factor C)
D Other elongation factors
E GSTEN00025786G001 unnamed protein product K10742 DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 [EC:5.6.2.3 3.1.-.-]
E GSTEN00004156G001 unnamed protein product K04799 FEN1; flap endonuclease-1 [EC:3.1.-.-]
B DNA Replication Termination Factors
C Terminus site-binding protein
C DNA methylation enzymes
C Prevention of re-replication factors
B DNA Topoisomerases
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#[ BRITE | KEGG2 | KEGG ]
#Last updated: November 2, 2022