OmpR family
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PhoR-PhoB (phosphate starvation response)
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SenX3-RegX3 (phosphate starvation response)
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PhoQ-PhoP (magnesium transport)
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EnvZ-OmpR (osmotic stress response)
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RstB-RstA
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CpxA-CpxR (envelope stress response)
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CssS-CssR (secretion stress response)
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CreC-CreB (phosphate regulation)
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BaeS-BaeR (envelope stress response)
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BasS-BasR (antimicrobial peptide resistance)
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CusS-CusR (copper tolerance)
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QseC-QseB (quorum sensing)
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KdpD-KdpE (potassium transport)
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TorS-TorR (TMAO respiration)
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ArcB-ArcA (anoxic redox control)
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TctE-TctD (tricarboxylic acid transport)
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K07649 tctE; two-component system, OmpR family, sensor histidine kinase TctE [EC:2.7.13.3]
K07774 tctD; two-component system, OmpR family, response regulator TctD
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ResE-ResD (aerobic and anaerobic respiration)
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VicK-VicR (cell wall metabolism)
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MprB-MprA (maintenance of persistent infection)
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MtrB-MtrA (osmotic stress response)
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PrrB-PrrA (intracellular multiplication)
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TrcS-TrcR
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NrsS-NrsR (nickel tolerance)
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ManS-ManR (manganese homeostasis)
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NblS-NblR (photosynthesis)
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SasA-RpaAB (circadian timing mediating)
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SaeS-SaeR (staphylococcal virulence regulation)
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BceS-BceR (bacitracin transport)
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BraS-BraR (bacitracin transport)
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GraS-GraR (cationic antimicrobial peptide transport)
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YxdK-YxdJ (antimicrobial peptide response)
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ChvG-ChvI (acidity sensing)
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CiaH-CiaR
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ParS-ParR (polymyxin-adaptive resistance)
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AdeS-AdeR
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VanS-VanR (VanB type vancomycin resistance)
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VanS-VanR (VanE type vancomycin resistance)
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VanS-VanR (actinomycete type vancomycin resistance)
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ArlS-ArlR (virulence regulation)
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Ihk-Irr (virulence regulation)
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PfeS-PfeR (enterobactin-dependent iron acquisition)
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NisK-NisR (lantibiotic biosynthesis)
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Unclassified
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K21603 ftcR; two-component system, OmpR family, flagellar system response regulator FtcR
K02484 K02484; two-component system, OmpR family, sensor kinase [EC:2.7.13.3]
K02483 K02483; two-component system, OmpR family, response regulator
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NarL family
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Spo family
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CitB family
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LytTR family
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NtrC family
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CheA family
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CheA-CheYBV (chemotaxis)
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ChpA-ChpB/PilGH (chemosensory)
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K06596 chpA; chemosensory pili system protein ChpA (sensor histidine kinase/response regulator)
K02657 pilG; twitching motility two-component system response regulator PilG
K02658 pilH; twitching motility two-component system response regulator PilH
K06597 chpB; chemosensory pili system protein ChpB (putative protein-glutamate methylesterase)
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PixL-PixGH (positive phototaxis)
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WspE-WspRF (chemosensory)
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Cph1-Rcp1 (light response)
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Cell cycle family
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Lux family
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LuxR family
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Other families
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FlrB-FlrC (polar flagellar synthesis)
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AauS-AauR (acidic amino acids utilization)
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SLN1-YPD1-SSK1/SKN7 (osmosensing)
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K11231 SLN1; osomolarity two-component system, sensor histidine kinase SLN1 [EC:2.7.13.3]
K19690 CHK1; osomolarity two-component system, sensor histidine kinase CHK1 [EC:2.7.13.3]
K19691 NIK1, TCSC; osomolarity two-component system, sensor histidine kinase NIK1 [EC:2.7.13.3]
K19692 TCSA; osomolarity two-component system, sensor histidine kinase TcsA [EC:2.7.13.3]
K11232 YPD1; osomolarity two-component system, phosphorelay intermediate protein YPD1
K11233 SSK1; osomolarity two-component system, response regulator SSK1
K15859 SKN7; osomolarity two-component system, response regulator SKN7
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RpfC-RpfG (cell-to-cell signaling)
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GlnK-GlnL (glutamine utilization)
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HspS-HspR (hexose phosphates uptake)
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YesM-YesN
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CikA
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RegB-RegA (redox response)
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FitF-FitH (insecticidal toxin regulation)
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PhcS-PhcRQ
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SagS-HptB-HsbR (swarming activity and biofilm formation)
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PdtaS-PdtaR
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NasS-NasT
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Unclassified
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