G Protein-Coupled Receptors

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 Rhodopsin family
   Biogenic amine
   Peptide
     Adrenomedullin (G10D)
     Adropin
     Apelin
     Anaphylatoxin
     Angiotensin
     BigLEN
     Bombesin
     Bradykinin
     Cholecystokinin
     Endothelin
     fMet-Leu-Phe
     Follicle stimulating hormone (FSH)
     Galanin
     Ghrelin
     Gonadotropin-releasing hormone (GnRH)
     Lutropin-choriogonadotropic hormone
     Melanin-concentrating hormone (MCH)
     Melanocortin
     Motilin
     Neuromedin U
     Neuropeptide FF
     Neuropeptide S
     Neuropeptide W / neuropeptide B
     Neuropeptide Y
     Neurotensin
     Opioid
     Orexigenic neuropeptide QRFP
     Orexin
     Oxytocin
     Prokineticin
     Prolactin-releasing peptide (PrRP)
     Prosaposin
     Relaxin
       K04306  RXFP1, LGR7; relaxin family peptide receptor 1
       K04307  RXFP2, LGR8; relaxin family peptide receptor 2
       K08397  RXFP3, RLN3R1; relaxin family peptide receptor 3
       K08398  RXFP4, RLN3R2; relaxin family peptide receptor 4
     Somatostatin
     Tachykinin
     Thrombin
     Thyrotropin
     Thyrotropin-releasing hormone (TRH)
     Urotensin II
     Vasopressin
     Neuropeptide receptors
   Chemokine
   Base and nucleoside
   Lipid
   Vision
   Others
     Alpha-ketoglutarate
     Cannabinoid
     Estrogen
     Hydroxy-carboxylic acid
     L-Tryptophan and L-Phenylalanine
     Mas proto-oncogene and Mas-related (MRGs)
       K04303  MAS1; proto-oncogene Mas
       K04324  MAS1L; Mas-related G-protein coupled receptor MRG
       K08392  MRGPRD; Mas-related G protein-coupled receptor member D
       K08393  MRGPRE; Mas-related G protein-coupled receptor member E
       K08394  MRGPRF; Mas-related G protein-coupled receptor member F
       K08395  MRGPRG; Mas-related G protein-coupled receptor member G
       K22793  MRGPRH; Mas-related G protein-coupled receptor member H
       K08396  MRGPRX; Mas-related G protein-coupled receptor member X
     Melatonin
     Oxysterol
     Platelet activating factor
     Proton-sensing GPCRs
     R-spondin
     Super conserved receptor expressed in brain (SREB)
     Trissin
     Orphan GPCRs / unclassified GPCRs
 
 Secretin receptor family
 
 Adhesion receptor family
 
 Metabotropic glutamate receptor family
 
 Frizzled / Smoothened family
 
 Others

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Last updated: April 22, 2025
Classification taken and modified from GPCRDB