Messenger RNA Biogenesis - Ursus arctos horribilis

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     KO
 Eukaryotic type
   mRNA processing factors
   mRNA surveillance and transport factors
     Transport factors
       EJC complex
       TREX complex
       Nuclear pore complex
       Ran-mediated transport factors
       eIF4F and regulatory proteins
         113263893 EIF4E1B; eukaryotic translation initiation factor 4E type 1B
         113263123 EIF4E; eukaryotic translation initiation factor 4E
         113250342 EIF4E2; eukaryotic translation initiation factor 4E type 2 isoform X1
         113271150 EIF4A1; eukaryotic initiation factor 4A-I isoform X1
         113253897 EIF4A2; eukaryotic initiation factor 4A-II
         113268553 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X1
         113248990 EIF4G2; eukaryotic translation initiation factor 4 gamma 2
         113254213 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1
         113257571 EIF4B; eukaryotic translation initiation factor 4B isoform X1
         113267781 EIF4H; eukaryotic translation initiation factor 4H
         113262099 EIF4EBP1; eukaryotic translation initiation factor 4E-binding protein 1
         113259142 EIF4EBP2; eukaryotic translation initiation factor 4E-binding protein 2
         113261832 EIF4EBP3; eukaryotic translation initiation factor 4E-binding protein 3
         113245060 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter isoform X1
         113262684 ANGEL2; protein angel homolog 2 isoform X1
         113270304 ANGEL1; protein angel homolog 1
         113254657 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1
         113241891 FMR1; synaptic functional regulator FMR1 isoform X1
         113271143 FXR2; fragile X mental retardation syndrome-related protein 2
         113263582 CYFIP1; cytoplasmic FMR1-interacting protein 1 isoform X1
         113264018 CYFIP2; cytoplasmic FMR1-interacting protein 2
         113264003 GEMIN5; gem-associated protein 5 isoform X1
         113245668 TACC3; transforming acidic coiled-coil-containing protein 3
         113243165 CPEB3; cytoplasmic polyadenylation element-binding protein 3 isoform X1
         113263742 CPEB1; cytoplasmic polyadenylation element-binding protein 1 isoform X1
         113266689 CPEB2; cytoplasmic polyadenylation element-binding protein 2 isoform X1
         113264113 CPEB4; cytoplasmic polyadenylation element-binding protein 4 isoform X1
         113248381 ATP-dependent RNA helicase DDX3X-like isoform X1
         113265882 DDX3X; ATP-dependent RNA helicase DDX3X isoform X1
         113267848 GIGYF1; GRB10-interacting GYF protein 1 isoform X1
         113250337 GIGYF2; GRB10-interacting GYF protein 2 isoform X1
         113242175 PABPC5; polyadenylate-binding protein 5
         113252872 PABPC1; polyadenylate-binding protein 1 isoform X1
         113268249 PABPC4; polyadenylate-binding protein 4 isoform X1
         113255674 PABPC4L; polyadenylate-binding protein 4-like
         113242138 LOW QUALITY PROTEIN: polyadenylate-binding protein 4-like
         113258643 PABPC1L; polyadenylate-binding protein 1-like isoform X1
         113246576 polyadenylate-binding protein 1-like 2
         113260958 PAIP1; polyadenylate-binding protein-interacting protein 1 isoform X1
         113243737 SKIV2L; helicase SKI2W
         113248806 DEAF1; deformed epidermal autoregulatory factor 1 homolog isoform X1
         113241121 malignant T-cell-amplified sequence 1-like
         113270913 MCTS1; malignant T-cell-amplified sequence 1 isoform X1
         113266915 DENR; density-regulated protein
K03259 EIF4E; translation initiation factor 4E 
K03259 EIF4E; translation initiation factor 4E 
K03259 EIF4E; translation initiation factor 4E 
K03257 EIF4A; translation initiation factor 4A 
K03257 EIF4A; translation initiation factor 4A 
K03260 EIF4G; translation initiation factor 4G 
K03260 EIF4G; translation initiation factor 4G 
K03260 EIF4G; translation initiation factor 4G 
K03258 EIF4B; translation initiation factor 4B 
K24086 EIF4H; translation initiation factor 4H 
K07205 EIF4EBP1; eukaryotic translation initiation factor 4E binding protein 1 
K18644 EIF4EBP2; eukaryotic translation initiation factor 4E binding protein 2 
K18645 EIF4EBP3; eukaryotic translation initiation factor 4E binding protein 3 
K18728 EIF4ENIF1; eukaryotic translation initiation factor 4E transporter 
K18729 ANGEL; protein angel 
K18729 ANGEL; protein angel 
K15516 FMR; fragile X mental retardation protein 
K15516 FMR; fragile X mental retardation protein 
K15516 FMR; fragile X mental retardation protein 
K05749 CYFIP; cytoplasmic FMR1 interacting protein 
K05749 CYFIP; cytoplasmic FMR1 interacting protein 
K13133 GEMIN5; gem associated protein 5 
K14283 TACC3; transforming acidic coiled-coil-containing protein 3 
K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
K02602 CPEB; cytoplasmic polyadenylation element-binding protein 
K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13] 
K11594 DDX3X; ATP-dependent RNA helicase DDX3X [EC:3.6.4.13] 
K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein 
K18730 GIGYF; PERQ amino acid-rich with GYF domain-containing protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K14322 PAIP1; polyadenylate-binding protein-interacting protein 1 
K12599 SKI2; antiviral helicase SKI2 [EC:3.6.4.-] 
K23041 DEAF1; deformed epidermal autoregulatory factor 1 
K07575 MCTS; malignant T-cell-amplified sequence 
K07575 MCTS; malignant T-cell-amplified sequence 
K24272 DENR; density-regulated protein 
       Other transport factors
     Surveillance factors
     Factors involved in mRNA localization
     mRNA cycle factors
       Common to processing body (P body) and stress granule
       P-body specific factors
       Stress granule specific factors
         113251996 TIAL1; nucleolysin TIAR isoform X1
         113244242 TIA1; nucleolysin TIA-1 isoform X1
         113242175 PABPC5; polyadenylate-binding protein 5
         113252872 PABPC1; polyadenylate-binding protein 1 isoform X1
         113268249 PABPC4; polyadenylate-binding protein 4 isoform X1
         113255674 PABPC4L; polyadenylate-binding protein 4-like
         113242138 LOW QUALITY PROTEIN: polyadenylate-binding protein 4-like
         113258643 PABPC1L; polyadenylate-binding protein 1-like isoform X1
         113246576 polyadenylate-binding protein 1-like 2
         113258696 STAU1; double-stranded RNA-binding protein Staufen homolog 1 isoform X1
         113253047 STAU2; double-stranded RNA-binding protein Staufen homolog 2 isoform X1
         113254657 FXR1; fragile X mental retardation syndrome-related protein 1 isoform X1
         113241891 FMR1; synaptic functional regulator FMR1 isoform X1
         113271143 FXR2; fragile X mental retardation syndrome-related protein 2
         113258759 ZBP1; Z-DNA-binding protein 1 isoform X1
         113242911 ELAVL1; ELAV-like protein 1
         113263982 G3BP1; ras GTPase-activating protein-binding protein 1
         113254058 EIF2A; eukaryotic translation initiation factor 2A
         113247725 EIF3B; eukaryotic translation initiation factor 3 subunit B
         113271150 EIF4A1; eukaryotic initiation factor 4A-I isoform X1
         113253897 EIF4A2; eukaryotic initiation factor 4A-II
         113244539 EIF4A3; eukaryotic initiation factor 4A-III
         113257571 EIF4B; eukaryotic translation initiation factor 4B isoform X1
         113268553 EIF4G3; eukaryotic translation initiation factor 4 gamma 3 isoform X1
         113248990 EIF4G2; eukaryotic translation initiation factor 4 gamma 2
         113254213 EIF4G1; eukaryotic translation initiation factor 4 gamma 1 isoform X1
         113242238 RPS6KA3; ribosomal protein S6 kinase alpha-3 isoform X1
         113268455 RPS6KA1; ribosomal protein S6 kinase alpha-1 isoform X1
         113259645 RPS6KA2; ribosomal protein S6 kinase alpha-2 isoform X1
         113242134 RPS6KA6; ribosomal protein S6 kinase alpha-6
         113261532 RACK1; receptor of activated protein C kinase 1
         113248591 TNF receptor-associated factor 2 isoform X1
         113248645 TNF receptor-associated factor 2 isoform X1
         113244330 nuclear RNA export factor 2-like
         113248105 NXF3; LOW QUALITY PROTEIN: nuclear RNA export factor 3
         113250088 nuclear RNA export factor 5-like
         113250092 nuclear RNA export factor 2-like
         113246935 NXF1; nuclear RNA export factor 1
         113265929 HDAC6; histone deacetylase 6 isoform X1
         113251399 TDRD3; tudor domain-containing protein 3 isoform X1
         113257624 LARP4; la-related protein 4 isoform X1
         113241104 LARP4B; la-related protein 4B
K13201 TIA1; nucleolysin TIA-1/TIAR 
K13201 TIA1; nucleolysin TIA-1/TIAR 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K13126 PABPC; polyadenylate-binding protein 
K17597 STAU; double-stranded RNA-binding protein Staufen 
K17597 STAU; double-stranded RNA-binding protein Staufen 
K15516 FMR; fragile X mental retardation protein 
K15516 FMR; fragile X mental retardation protein 
K15516 FMR; fragile X mental retardation protein 
K12965 ZBP1; Z-DNA binding protein 1 
K13088 ELAVL1; ELAV-like protein 1 
K17265 G3BP1; Ras GTPase-activating protein-binding protein 1 [EC:3.6.4.12 3.6.4.13] 
K15026 EIF2A; translation initiation factor 2A 
K03253 EIF3B; translation initiation factor 3 subunit B 
K03257 EIF4A; translation initiation factor 4A 
K03257 EIF4A; translation initiation factor 4A 
K13025 EIF4A3; ATP-dependent RNA helicase [EC:3.6.4.13] 
K03258 EIF4B; translation initiation factor 4B 
K03260 EIF4G; translation initiation factor 4G 
K03260 EIF4G; translation initiation factor 4G 
K03260 EIF4G; translation initiation factor 4G 
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1] 
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1] 
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1] 
K04373 RPS6KA; ribosomal protein S6 kinase alpha-1/2/3/6 [EC:2.7.11.1] 
K14753 RACK1; guanine nucleotide-binding protein subunit beta-2-like 1 protein 
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27] 
K03173 TRAF2; TNF receptor-associated factor 2 [EC:2.3.2.27] 
K14284 NXF; nuclear RNA export factor 
K14284 NXF; nuclear RNA export factor 
K14284 NXF; nuclear RNA export factor 
K14284 NXF; nuclear RNA export factor 
K14284 NXF; nuclear RNA export factor 
K11407 HDAC6; histone deacetylase 6 [EC:3.5.1.98] 
K18404 TDRD3; tudor domain-containing protein 3 
K18763 LARP4; la-related protein 4 
K18763 LARP4; la-related protein 4 
   mRNA degradation factors
 
 Prokaryotic type

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Last updated: July 16, 2020