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Name |
Description |
Object |
Legend |
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map04620
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Toll-like receptor signaling pathway |
Specific families of pattern recognition receptors are responsible for detecting microbial pathogens... |
K05415 (IFNB) K04467 (IKBKA) K03175 (TRAF6) K04730 (IRAK1) K04733 (IRAK4) K04729 (MYD88) K04729 (MYD... |
...MyD88 Rac1 JNK IL-1β TBK1 TRAF6 IKKε FADD IL-6 RANTES TAB1 AKT TAB2 STAT1 IκBα TNFα IRF3 CD80 TLR2 M... |
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map04621
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NOD-like receptor signaling pathway |
Specific families of pattern recognition receptors are responsible for detecting various pathogens a... |
C00238 (Potassium cation) C01245 (D-myo-Inositol 1,4,5-trisphosphate) C00076 (Calcium cation) C00002... |
...obial peptides IL-18 IL-6 TNFα IL-8 CXCL MCP-1 RANTES NFkB IFI16 dsDNA DNA virus IL-1β IFNα/β IFNα/β... |
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map05020
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Prion disease |
Prion diseases, also termed transmissible spongiform encephalopathies (TSEs), are a group of fatal n... |
C00575 (3',5'-Cyclic AMP) C00027 (Hydrogen peroxide), C00704 (Superoxide) C02140 (Corticosterone) C0... |
... Regulation of autophagy Microglia Erk1/2 Egr1 RANTES Activation Microglia migration IL-1 IL-6 Proin... |
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map05120
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Epithelial cell signaling in Helicobacter pylori infection |
Two major virulence factors of H. pylori are the vacuolating cytotoxin (VacA) and the cag type-IV se... |
C01342 (NH4+) C00080 (H+) C00014 (Ammonia) G00263 (Lewis b antigen) C00698 (Cl-) C00086 (Urea) G0024... |
...KK4 IKKα IKKγ IKKβ IκBα ATPeV CASP3 PAK1 NF-κB RANTES GRO-α IL-8 Cdc42 Rac1 NIK PrtC UreB UreA CagPA... |
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map05131
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Shigellosis |
Shigellosis, or bacillary dysentery, is an intestinal infection caused by Shigella, a genus of enter... |
C00338 (Lipopolysaccharide) C00165 (Diacylglycerol) C00165 (Diacylglycerol) C11472 (D-glycero-beta-D... |
... UBC13 OspI IpaH9.8 ABIN1 IpaH9.8 U2AF35 mRNA RANTES IL-1β IL-8 GM-CSF CD14 SCF β-TrCP OspG IpaH4.5... |
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map05142
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Chagas disease |
Trypanosoma cruzi is an intracellular protozoan parasite that causes Chagas disease, also called Ame... |
C00062 (L-Arginine) C00533 (Nitric oxide) C01245 (D-myo-Inositol 1,4,5-trisphosphate) C00076 (Calciu... |
... cruzi amastigote Parasitophorous vacuole Tc52 RANTES IκB NFκB IL2 DNA TLR6 CHAGAS DISEASE ACE Inhi... |
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map05164
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Influenza A |
Influenza is a contagious respiratory disease caused by influenza virus infection. Influenza A virus... |
C00080 (H+) C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C00027 (Hydrogen peroxide) K01340 (E3.... |
...F9 MxA OAS ADAR PML CIITA MHCII NS1 IFNα SOCS3 RANTES IL8 IFNβ ICAM1 IL1 IL6 TNFα IL12 PKR p58IPK HS... |
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map05168
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Herpes simplex virus 1 infection |
Herpes simplex virus 1(HSV-1) is a common human pathogen, which initially infects orofacial mucosal ... |
C20640 (Cyclic GMP-AMP) C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C20935 (2-5A) K05468 (LTA)... |
...2 TAK1 IRF3/7 IκB IFNα IL12 TNFα IL1β IL6 CCL2 RANTES VP16 Oct-1 HCF TRAF6 IKKε TBK1 RIG-I IPS MDA5 ... |
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map05417
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Lipid and atherosclerosis |
Atherosclerosis is a chronic inflammatory disease marked by a narrowing of the arteries from lipid-r... |
C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C21011 ([Protein]-N(epsilon)-(carboxymethyl)lysine... |
...tive burst rap1 oxLDL mmLDL Nrf2 ROS Apoptosis RANTES MIP-1α Pro-inflammatory Pro-inflammatory TAK1 ... |