Pathway Maps

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KEGG PATHWAY is a collection of manually drawn pathway maps representing our knowledge on the molecular interaction, reaction and relation networks for: KEGG PATHWAY is a reference database for Pathway Mapping.

Pathway Identifiers

Each pathway map is identified by the combination of 2-4 letter prefix code and 5 digit number (see KEGG Identifier). The prefix has the following meaning:
manually drawn reference pathway
reference pathway highlighting KOs
reference metabolic pathway highlighting EC numbers
reference metabolic pathway highlighting reactions
organism-specific pathway generated by converting KOs to gene identifiers
and the numbers starting with the following:
global map (lines linked to KOs)
overview map (lines linked to KOs)
chemical structure map (no KO expansion)
drug structure map (no KO expansion)
regular map (boxes linked to KOs)
are used for different types of maps.

1. Metabolism

1.0 Global and overview maps
1.1 Carbohydrate metabolism
1.2 Energy metabolism
1.3 Lipid metabolism
1.4 Nucleotide metabolism
1.5 Amino acid metabolism
1.6 Metabolism of other amino acids
1.7 Glycan biosynthesis and metabolism
1.8 Metabolism of cofactors and vitamins
1.9 Metabolism of terpenoids and polyketides
1.10 Biosynthesis of other secondary metabolites
1.11 Xenobiotics biodegradation and metabolism
1.12 Chemical structure transformation maps

2. Genetic Information Processing

2.1 Transcription
2.2 Translation
2.3 Folding, sorting and degradation
2.4 Replication and repair

3. Environmental Information Processing

3.1 Membrane transport
3.2 Signal transduction
3.3 Signaling molecules and interaction

4. Cellular Processes

4.1 Transport and catabolism
4.2 Cell growth and death
4.3 Cellular community - eukaryotes
4.4 Cellular community - prokaryotes
4.5 Cell motility

5. Organismal Systems

5.1 Immune system
5.2 Endocrine system
5.3 Circulatory system
5.4 Digestive system
5.5 Excretory system
5.6 Nervous system
5.7 Sensory system
5.8 Development
5.9 Aging
5.10 Environmental adaptation

6. Human Diseases

6.1 Cancer: overview
6.2 Cancer: specific types
6.3 Immune disease
6.4 Neurodegenerative disease
6.5 Substance dependence
6.6 Cardiovascular disease
6.7 Endocrine and metabolic disease
6.8 Infectious disease: bacterial
6.9 Infectious disease: viral
6.10 Infectious disease: parasitic
6.11 Drug resistance: antimicrobial
6.12 Drug resistance: antineoplastic

7. Drug Development

7.1 Chronology: Antiinfectives
7.2 Chronology: Antineoplastics
7.3 Chronology: Nervous system agents
7.4 Chronology: Other drugs
7.5 Target-based classification: G protein-coupled receptors
7.6 Target-based classification: Nuclear receptors
7.7 Target-based classification: Ion channels
7.8 Target-based classification: Transporters
7.9 Target-based classification: Enzymes
7.10 Structure-based classification
7.11 Skeleton-based classification

Pathway Mapping

KEGG PATHWAY mapping is the process to map molecular datasets, especially large-scale datasets in genomics, transcriptomics, proteomics, and metabolomics, to the KEGG pathway maps for biological interpretaion of higher-level systemic functions.

Last updated: May 13, 2019
KEGG GenomeNet Kanehisa Laboratories