| Entry |
Thumbnail Image |
Name |
Description |
Object |
Legend |
|
hsa04140
|
|
Autophagy - animal |
Autophagy (or macroautophagy) is a cellular catabolic pathway involving in protein degradation, orga... |
...11345 (GABARAPL2), 23710 (GABARAPL1), 392288 (MAP1LC3BP1), 440738 (MAP1LC3C), 643246 (MAP1LC3B2), 81... |
PI3P AUTOPHAGY - ANIMAL Nutrient starvation (Amino acids, glucose) mTORC1 complex ER stress ROS Lo... |
|
hsa05131
|
|
Shigellosis |
Shigellosis, or bacillary dysentery, is an intestinal infection caused by Shigella, a genus of enter... |
...54 (ATG16L1) 9474 (ATG5) 9140 (ATG12) 392288 (MAP1LC3BP1), 440738 (MAP1LC3C), 643246 (MAP1LC3B2), 81... |
SHIGELLOSIS Shigella dysenteria Shigella flexneri Shigella boydii Shigella sonnei TNF-R1 TNFα IκBα I... |
|
hsa04137
|
|
Mitophagy - animal |
Mitochondria act as the energy powerhouse of the cell, and are essential for eukaryotic cells to gro... |
...11345 (GABARAPL2), 23710 (GABARAPL1), 392288 (MAP1LC3BP1), 440738 (MAP1LC3C), 643246 (MAP1LC3B2), 81... |
MITOPHAGY - ANIMAL PINK1 Parkin OPTN TBK1 P62 NDP52 NBR1 TAX1BP1 ARIH1 SIAH1 HUWE1 GP78 MUL1 SMURF... |
|
hsa05167
|
|
Kaposi sarcoma-associated herpesvirus infection |
Kaposi sarcoma-associated herpesvirus (KSHV), also known as human herpesvirus 8 (HHV-8), is the most... |
...) 131450 (CD200R1), 344807 (CD200R1L) 392288 (MAP1LC3BP1), 440738 (MAP1LC3C), 643246 (MAP1LC3B2), 81... |
IFN-α/β TRAF3 IRF7 IFN-β IFN-α IKK JNK TBK1 IKKε AKT STAT1 IκBα IRF3 TLR3 TRIF KAPOSI SARCOMA-ASSO... |
|
hsa04216
|
|
Ferroptosis |
Ferroptosis is a regulated form of cell death and characterized by a production of reactive oxygen s... |
...9A14), 64116 (SLC39A8) 4891 (SLC11A2) 392288 (MAP1LC3BP1), 440738 (MAP1LC3C), 643246 (MAP1LC3B2), 81... |
FERROPTOSIS SLC7A11 Glutamate Cystine p53 GPX4 GSH Mitochondria VDAC2/3 Erastin Cysteine GCL γGC SLC... |
|
hsa04371
|
|
Apelin signaling pathway |
Apelin is an endogenous peptide capable of binding the apelin receptor (APJ), which was originally d... |
...PS6KB2) 30849 (PIK3R4), 5289 (PIK3C3) 392288 (MAP1LC3BP1), 440738 (MAP1LC3C), 643246 (MAP1LC3B2), 81... |
APELIN SIGNALING PATHWAY APJ AMPK Sphk1 PAI-1 PI3K Akt MEK1/2 ERK1/2 P70S6K PLCβ IP3 IP3R RyR mTOR... |
|
hsa04621
|
|
NOD-like receptor signaling pathway |
Specific families of pattern recognition receptors are responsible for detecting various pathogens a... |
...11345 (GABARAPL2), 23710 (GABARAPL1), 392288 (MAP1LC3BP1), 440738 (MAP1LC3C), 643246 (MAP1LC3B2), 81... |
ASC pro-CASP1 ASC pro-CASP1 ASC pro-CASP1 ASC pro-CASP1 NOD1 NOD2 iE-DAP RIP2 IKKα/β TAK1 TAB NLRP1 ... |
|
hsa05014
|
|
Amyotrophic lateral sclerosis |
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by a progressive d... |
...27 (TUBB1), 84617 (TUBB6) 6647 (SOD1) 392288 (MAP1LC3BP1), 440738 (MAP1LC3C), 643246 (MAP1LC3B2), 81... |
SOD1 EAAT2 AMYOTROPHIC LATERAL SCLEROSIS Motor neuron Astrocyte Presynaptic neuron Microglial cell... |
|
hsa05022
|
|
Pathways of neurodegeneration - multiple diseases |
Neurodegeneration is generally defined as progressive, irreversible loss of neurons, which may affec... |
...9110 (TBK1) 10010 (TANK) 10133 (OPTN) 392288 (MAP1LC3BP1), 440738 (MAP1LC3C), 643246 (MAP1LC3B2), 81... |
PATHWAYS OF NEURODEGENERATION - MULTIPLE DISEASES Endoplasmic reticulum (ER) PrP ER stress CASP... |