Entry |
Thumbnail Image |
Name |
Description |
Object |
Legend |
map05226
|
|
Gastric cancer |
Gastric cancer (GC) is one of the world's most common cancers. According to Lauren's histological cl... |
C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C05981 (Phosphatidylinositol-3,4,5-trisphosphate) ... |
GASTRIC CANCER Ras Raf MEK ERK1/2 Shc Grb2 SOS mTOR S6K PI3K-Akt signaling pathway Ras Raf MEK ERK1... |
map04112
|
|
Cell cycle - Caulobacter |
...ed around three master regulator proteins, DnaA, GcrA, and CtrA. DnaA and GcrA together drive the sy... |
C16463 (3',5'-Cyclic diGMP) K13590 (dgcB) K13589 (cpdR) K03544 (clpX) K13591 (popA) K13592 (rcdA) K1... |
DgcB CELL CYCLE - Caulobacter CpdR ClpX PopA RcdA DivJ PleC PleD c-di-GMP CckA ChpT PdeA Flagella... |
map04024
|
|
cAMP signaling pathway |
...ac), and cyclic nucleotide-gated ion channels (CNGCs). PKA modulates, via phosphorylation, a number ... |
...16367 (EDN2), K05227 (EDN3) K05237 (SST) K05259 (GCG) K05262 (ADCYAP) K05264 (VIP) K08522 (CGA), K05... |
...G PMCA Rap1 Raf1 MEK Arap3 B-Raf PLCε JNK CREB CNGC Rho ROCK MYPT1 CaMKs GPCR Dopamine PGI2 5-HT Ach... |
map04730
|
|
Long-term depression |
...eceptors, opens voltage-gated calcium channels (VGCCs) and causes a generalized influx of calcium. T... |
C00219 (Arachidonate) C00533 (Nitric oxide) C00641 (1,2-Diacyl-sn-glycerol) C01245 (D-myo-Inositol 1... |
...IGF1R CRFR1 DAG Glutamate CRF IGF1 GUCY δ2R PKG VGCC AMPAR ERK1/2 MEK1/2 Raf Ras PP2A PTK mGluR1 IP3... |
map02025
|
|
Biofilm formation - Pseudomonas aeruginosa |
...-di-GMP is facilitated by diguanylate cyclases (DGC) and phosphodiesterases (PDE). High intracellula... |
C00575 (3',5'-Cyclic AMP) C11837 (N-Butyryl-L-homoserine lactone) C20643 (2-Heptyl-4(1H)-quinolone),... |
PilI PilH PilG PilJ ChpA CyaB cAMP CpdA Vfr LasI LasR RhlI PqsA PqsB PqsC PqsD PqsH MvfR BIOFILM FO... |
map05010
|
|
Alzheimer disease |
... synaptic proteins, including NMDAR, mGluR5 and VGCC, leading to the overfilling of neurons with cal... |
C01245 (D-myo-Inositol 1,4,5-trisphosphate) C00076 (Calcium cation) C00076 (Calcium cation) C00533 (... |
PEN2 PSEN NCSTN APH-1 γ-Secretase BACE ADAM10/17 β-Secretase α-Secretase TNF Microglia AICD C99 sAPP... |
map01100
|
|
Metabolic pathways |
|
...94 (UGT73B44), K26495 (UGT91AP1), R13165 K00605 (gcvT), 2.1.2.10, R04125 K00605 (gcvT), 2.1.2.10, R0... |
Monoterpenoid biosynthesis One carbon pool by folate Flavonoid biosynthesis Starch and sucrose metab... |
map01110
|
|
Biosynthesis of secondary metabolites |
|
...858 K12699 (MAT), R05870 K16431 (cepH), K21185 (sgcE6), R11368 K12695 (RG), 2.4.1.219, 3.2.1.125, R0... |
Starch and sucrose metabolism Benzoxazinoid biosynthesis Indole diterpene alkaloid biosynthesis Phos... |
map01059
|
|
Biosynthesis of enediyne antibiotics |
Enediyne natural products are potent antitumor antibiotics produced by a variety of Actinomycetes. E... |
...-4,5-dihydroxy-beta-phenylalanyl-[pcp]) K20159 (sgcD), K21175 (sgcD1), 2.6.1.86, R08956 K20156 (sgcG... |
...ate 1.3.8.16 3-(1-Carboxyvinyloxy)-anthranilate SgcD5 3,4-Dihydro-2-methylene-3-oxo-2H-1,4-benzoxazi... |
map01200
|
|
Carbon metabolism |
Carbon metabolism is the most basic aspect of life. This map presents an overall view of central car... |
...0918 (pfkC), R00756, R05805 K00844 (HK), K12407 (GCK), K00845 (glk), K25026 (glk), K00886 (ppgK), K0... |
HCO HCHO HCHO HCO HCO AcCoA CARBON METABOLISM Fructose-6P Ribulose-1,5P Glycerate-3P THF Glucose Gl... |
map01120
|
|
Microbial metabolism in diverse environments |
|
...R08092 K00632 (fadA), 2.3.1.16, R08091 K01640 (HMGCL), 4.1.3.26, 4.1.3.4, R08090 K13779 (atuE), 4.2.... |
Chlorocyclohexane and chlorobenzene degradation Xylene degradation Aminobenzoate degradation Naphtha... |
map01240
|
|
Biosynthesis of cofactors |
|
...212 (cofD), R09398 K11212 (cofD), R09398 K11204 (GCLC), K11205 (GCLM), K01919 (gshA), R00894 K11204 ... |
... Pimelate Pimeloyl-CoA Octanoyl-ACP AMP ATP ADP [GcvH]-dihydro-lipoyllysine [E2]-dihydro-lipoyllysin... |
map00512
|
|
Mucin type O-glycan biosynthesis |
O-glycans are a class of glycans that modify serine or threonine residues of proteins. Biosynthesis ... |
...antigen) G13153 G10794 2.4.1.148, R05910 K09662 (GCNT3), R05915 K00727 (GCNT1), 2.4.1.102, R05910 K0... |
...hr Core 7 GlcNAc GalNAc Ser/Thr Core 6 & F1α GCNT1 GCNT1 GalNAc GalNAc Ser/Thr Core 5 GlcNAc Gal... |
map00260
|
|
Glycine, serine and threonine metabolism |
Serine is derived from 3-phospho-D-glycerate, an intermediate of glycolysis [MD:M00020], and glycine... |
... (thrH), 2.7.1.39, R01771 K00281 (GLDC), K00282 (gcvPA), K00283 (gcvPB), 1.4.4.2, R03425 K00643 (E2.... |
...2,4-diaminobutyrate 3.5.1.125 DoeD DoeC 5.4.2.12 GCSH 2.1.1.156 2.1.1.157 2.1.1.161 1.1.1.381 Propan... |
map00650
|
|
Butanoate metabolism |
|
...R00410 K01907 (AACS), 6.2.1.16, R01357 K01640 (HMGCL), 4.1.3.4, R01360 K01641 (HMGCS), 2.3.3.10, R01... |
Biosynthesis of type II polyketide backbone 4.2.1.27 1.1.1.30 3.1.1.22 2.8.3.5 6.2.1.16 4.1.3.4 2.3.... |
map04922
|
|
Glucagon signaling pathway |
Glucagon is conventionally regarded as a counterregulatory hormone for insulin and plays a critical ... |
...K00161 (PDHA), K00162 (PDHB) K00873 (PK) K12407 (GCK) K00850 (pfkA) K01834 (PGAM) K05259 (GCG) K0458... |
...e Oxaloacetate PDH Glycolysis / glucogenesis PKM GCK F6P PEP 3-PGA 2-PGA F1,6P PFKL PGM Oxidative ph... |
map05410
|
|
Hypertrophic cardiomyopathy |
Hypertrophic cardiomyopathy (HCM) is a primary myocardial disorder with an autosomal dominant patter... |
...3240 (NOS1) K12959 (CAV3) K22194 (SSPN) K12563 (SGCD) K12564 (SGCG), K27062 (SGCZ) K12566 (SGCB) K12... |
...odelling ET1 Ang-II SNTA/B DTNA nNOS CAV3 SSPN SGCD SGCG SGCB SGCA |
map05412
|
|
Arrhythmogenic right ventricular cardiomyopathy |
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease that may... |
...6998 (DTNA) K13240 (NOS1) K12959 (CAV3) K12564 (SGCG), K27062 (SGCZ) K12563 (SGCD) K12566 (SGCB) K12... |
...nomic nervous system SSPN SNTA/B DTNA nNOS CAV3 SGCG SGCD SGCB SGCA |
map05414
|
|
Dilated cardiomyopathy |
Dilated cardiomyopathy (DCM) is a heart muscle disease characterised by dilation and impaired contra... |
...6998 (DTNA) K13240 (NOS1) K12959 (CAV3) K12564 (SGCG), K27062 (SGCZ) K12563 (SGCD) K12566 (SGCB) K12... |
... homeostasis Ang-II SSPN SNTA/B DTNA nNOS CAV3 SGCG SGCD SGCB SGCA |
map05416
|
|
Viral myocarditis |
Myocarditis is a cardiac disease associated with inflammation and injury of the myocardium. It resul... |
...92 (RAC1), K07860 (RAC2), K07861 (RAC3) K12564 (SGCG), K27062 (SGCZ) K12563 (SGCD) K12566 (SGCB) K12... |
...from the TJ Caveolin-1 Rac Actin reorganization SGCG SGCD SGCB SGCA SSPN SNTA/B DTNA nNOS CAV3 |