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Entry Thumbnail Image Name Description Object Legend
map05226 Gastric cancer Gastric cancer (GC) is one of the world's most common cancers. According to Lauren's histological cl... C05981 (Phosphatidylinositol-3,4,5-trisphosphate) C05981 (Phosphatidylinositol-3,4,5-trisphosphate) ... GASTRIC CANCER Ras Raf MEK ERK1/2 Shc Grb2 SOS mTOR S6K PI3K-Akt signaling pathway Ras Raf MEK ERK1...
map04112 Cell cycle - Caulobacter ...ed around three master regulator proteins, DnaA, GcrA, and CtrA. DnaA and GcrA together drive the sy... C16463 (3',5'-Cyclic diGMP) K13590 (dgcB) K13589 (cpdR) K03544 (clpX) K13591 (popA) K13592 (rcdA) K1... DgcB CELL CYCLE - Caulobacter CpdR ClpX PopA RcdA DivJ PleC PleD c-di-GMP CckA ChpT PdeA Flagella...
map04024 cAMP signaling pathway ...ac), and cyclic nucleotide-gated ion channels (CNGCs). PKA modulates, via phosphorylation, a number ... ...16367 (EDN2), K05227 (EDN3) K05237 (SST) K05259 (GCG) K05262 (ADCYAP) K05264 (VIP) K08522 (CGA), K05... ...G PMCA Rap1 Raf1 MEK Arap3 B-Raf PLCε JNK CREB CNGC Rho ROCK MYPT1 CaMKs GPCR Dopamine PGI2 5-HT Ach...
map04730 Long-term depression ...eceptors, opens voltage-gated calcium channels (VGCCs) and causes a generalized influx of calcium. T... C00219 (Arachidonate) C00533 (Nitric oxide) C00641 (1,2-Diacyl-sn-glycerol) C01245 (D-myo-Inositol 1... ...IGF1R CRFR1 DAG Glutamate CRF IGF1 GUCY δ2R PKG VGCC AMPAR ERK1/2 MEK1/2 Raf Ras PP2A PTK mGluR1 IP3...
map02025 Biofilm formation - Pseudomonas aeruginosa ...-di-GMP is facilitated by diguanylate cyclases (DGC) and phosphodiesterases (PDE). High intracellula... C00575 (3',5'-Cyclic AMP) C11837 (N-Butyryl-L-homoserine lactone) C20643 (2-Heptyl-4(1H)-quinolone),... PilI PilH PilG PilJ ChpA CyaB cAMP CpdA Vfr LasI LasR RhlI PqsA PqsB PqsC PqsD PqsH MvfR BIOFILM FO...
map05010 Alzheimer disease ... synaptic proteins, including NMDAR, mGluR5 and VGCC, leading to the overfilling of neurons with cal... C01245 (D-myo-Inositol 1,4,5-trisphosphate) C00076 (Calcium cation) C00076 (Calcium cation) C00533 (... PEN2 PSEN NCSTN APH-1 γ-Secretase BACE ADAM10/17 β-Secretase α-Secretase TNF Microglia AICD C99 sAPP...
map01100 Metabolic pathways ...94 (UGT73B44), K26495 (UGT91AP1), R13165 K00605 (gcvT), 2.1.2.10, R04125 K00605 (gcvT), 2.1.2.10, R0... Monoterpenoid biosynthesis One carbon pool by folate Flavonoid biosynthesis Starch and sucrose metab...
map01110 Biosynthesis of secondary metabolites ...858 K12699 (MAT), R05870 K16431 (cepH), K21185 (sgcE6), R11368 K12695 (RG), 2.4.1.219, 3.2.1.125, R0... Starch and sucrose metabolism Benzoxazinoid biosynthesis Indole diterpene alkaloid biosynthesis Phos...
map01059 Biosynthesis of enediyne antibiotics Enediyne natural products are potent antitumor antibiotics produced by a variety of Actinomycetes. E... ...-4,5-dihydroxy-beta-phenylalanyl-[pcp]) K20159 (sgcD), K21175 (sgcD1), 2.6.1.86, R08956 K20156 (sgcG... ...ate 1.3.8.16 3-(1-Carboxyvinyloxy)-anthranilate SgcD5 3,4-Dihydro-2-methylene-3-oxo-2H-1,4-benzoxazi...
map01200 Carbon metabolism Carbon metabolism is the most basic aspect of life. This map presents an overall view of central car... ...0918 (pfkC), R00756, R05805 K00844 (HK), K12407 (GCK), K00845 (glk), K25026 (glk), K00886 (ppgK), K0... HCO HCHO HCHO HCO HCO AcCoA CARBON METABOLISM Fructose-6P Ribulose-1,5P Glycerate-3P THF Glucose Gl...
map01120 Microbial metabolism in diverse environments ...R08092 K00632 (fadA), 2.3.1.16, R08091 K01640 (HMGCL), 4.1.3.26, 4.1.3.4, R08090 K13779 (atuE), 4.2.... Chlorocyclohexane and chlorobenzene degradation Xylene degradation Aminobenzoate degradation Naphtha...
map01240 Biosynthesis of cofactors ...212 (cofD), R09398 K11212 (cofD), R09398 K11204 (GCLC), K11205 (GCLM), K01919 (gshA), R00894 K11204 ... ... Pimelate Pimeloyl-CoA Octanoyl-ACP AMP ATP ADP [GcvH]-dihydro-lipoyllysine [E2]-dihydro-lipoyllysin...
map00512 Mucin type O-glycan biosynthesis O-glycans are a class of glycans that modify serine or threonine residues of proteins. Biosynthesis ... ...antigen) G13153 G10794 2.4.1.148, R05910 K09662 (GCNT3), R05915 K00727 (GCNT1), 2.4.1.102, R05910 K0... ...hr Core 7 GlcNAc GalNAc Ser/Thr Core 6 & F1α GCNT1 GCNT1 GalNAc GalNAc Ser/Thr Core 5 GlcNAc Gal...
map00260 Glycine, serine and threonine metabolism Serine is derived from 3-phospho-D-glycerate, an intermediate of glycolysis [MD:M00020], and glycine... ... (thrH), 2.7.1.39, R01771 K00281 (GLDC), K00282 (gcvPA), K00283 (gcvPB), 1.4.4.2, R03425 K00643 (E2.... ...2,4-diaminobutyrate 3.5.1.125 DoeD DoeC 5.4.2.12 GCSH 2.1.1.156 2.1.1.157 2.1.1.161 1.1.1.381 Propan...
map00650 Butanoate metabolism ...R00410 K01907 (AACS), 6.2.1.16, R01357 K01640 (HMGCL), 4.1.3.4, R01360 K01641 (HMGCS), 2.3.3.10, R01... Biosynthesis of type II polyketide backbone 4.2.1.27 1.1.1.30 3.1.1.22 2.8.3.5 6.2.1.16 4.1.3.4 2.3....
map04922 Glucagon signaling pathway Glucagon is conventionally regarded as a counterregulatory hormone for insulin and plays a critical ... ...K00161 (PDHA), K00162 (PDHB) K00873 (PK) K12407 (GCK) K00850 (pfkA) K01834 (PGAM) K05259 (GCG) K0458... ...e Oxaloacetate PDH Glycolysis / glucogenesis PKM GCK F6P PEP 3-PGA 2-PGA F1,6P PFKL PGM Oxidative ph...
map05410 Hypertrophic cardiomyopathy Hypertrophic cardiomyopathy (HCM) is a primary myocardial disorder with an autosomal dominant patter... ...3240 (NOS1) K12959 (CAV3) K22194 (SSPN) K12563 (SGCD) K12564 (SGCG), K27062 (SGCZ) K12566 (SGCB) K12... ...odelling ET1 Ang-II SNTA/B DTNA nNOS CAV3 SSPN SGCD SGCG SGCB SGCA
map05412 Arrhythmogenic right ventricular cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy (ARVC) is an inherited heart muscle disease that may... ...6998 (DTNA) K13240 (NOS1) K12959 (CAV3) K12564 (SGCG), K27062 (SGCZ) K12563 (SGCD) K12566 (SGCB) K12... ...nomic nervous system SSPN SNTA/B DTNA nNOS CAV3 SGCG SGCD SGCB SGCA
map05414 Dilated cardiomyopathy Dilated cardiomyopathy (DCM) is a heart muscle disease characterised by dilation and impaired contra... ...6998 (DTNA) K13240 (NOS1) K12959 (CAV3) K12564 (SGCG), K27062 (SGCZ) K12563 (SGCD) K12566 (SGCB) K12... ... homeostasis Ang-II SSPN SNTA/B DTNA nNOS CAV3 SGCG SGCD SGCB SGCA
map05416 Viral myocarditis Myocarditis is a cardiac disease associated with inflammation and injury of the myocardium. It resul... ...92 (RAC1), K07860 (RAC2), K07861 (RAC3) K12564 (SGCG), K27062 (SGCZ) K12563 (SGCD) K12566 (SGCB) K12... ...from the TJ Caveolin-1 Rac Actin reorganization SGCG SGCD SGCB SGCA SSPN SNTA/B DTNA nNOS CAV3

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