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Name |
Description |
Object |
Legend |
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map05410
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Hypertrophic cardiomyopathy |
...increase the ATP utilization by actomyosin at submaximal Ca2+ concentrations, which might cause an i... |
C00002 (ATP) C00076 (Calcium cation) C00076 (Calcium cation) C00076 (Calcium cation) C00076 (Calcium... |
HYPERTROPHIC CARDIOMYOPATHY DHPR RyR SERCA2a NCX Sarcoplasmic reticulum (SR) T-tubule Cardiac muscl... |
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map04010
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MAPK signaling pathway |
The mitogen-activated protein kinase (MAPK) cascade is a highly conserved module that is involved in... |
... (MAPKAPK3) K04374 (ATF4) K04454 (MEF2C) K04453 (MAX) K04452 (DDIT3) K04376 (ELK4) K04451 (TP53) K04... |
...7 ERK5 MEK5 NLK Cdc25B MSK1/2 MAPKAPK CREB MEF2C MAX GADD153 Sap1a p53 Elk-1 ATF-2 p38 PP5 MKK6 MKK3... |
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map03083
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Polycomb repressive complex |
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...470 (PCGF6) K09390 (E2F6) K04683 (TFDP1) K04453 (MAX) K23399 (MGA) K24387 (L3MBTL) K11586 (CBX3) K14... |
...RS BCOR KDM2 SKP1 USP7 ncPRC1.3/1.5 ncPRC1.6 MGA MAX E2F6 DP1 L3MBTL2 WDR5 HP1 HDAC ncPRC1 core CpG ... |
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map05200
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Pathways in cancer |
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...K06643 (MDM2) K09455 (MITF) K04377 (MYC) K04453 (MAX) K10500 (ZBTB17) K04503 (CCND1), K10151 (CCND2)... |
...PU.1 PU.1 C/EBPα C/EBPα AML1 p53 MDM2 MITF c-Myc Max Miz1 CyclinD p21 CDK4/6 E2F CDK2 CyclinE Skp2 C... |
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map05202
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Transcriptional misregulation in cancer |
In tumor cells, genes encoding transcription factors (TFs) are often amplified, deleted, rearranged ... |
...K09383 (PAX5) K06856 (IGH) K09109 (NMYC) K04453 (MAX) K04684 (SP1) K10500 (ZBTB17) K06643 (MDM2) K04... |
...oblastoma < Neuroendocrine cancers> MYCN Max (TF) Amplification SP-1 Miz-1 MDM2 Inhibition o... |
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map05222
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Small cell lung cancer |
Lung cancer is a leading cause of cancer death among men and women in industrialized countries. Smal... |
...219 (CKS1) K04399 (CASP9) K02084 (APAF1) K04453 (MAX) K04377 (MYC) K01110 (PTEN) K00922 (PIK3CA_B_D)... |
...noic acid p27 RXR RARβ PKB/Akt CKS1 CASP9 Apaf-1 Max Myc PTEN PI3K FAK FHIT CytC ECM SMALL CELL LU... |
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map07045
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Antineoplastics - protein kinase inhibitors |
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..., D06402 (Sunitinib malate (JAN/USAN)) D05819 (Semaxanib (USAN/INN)) D03252 (Bosutinib (USAN)), D097... |
...zopanib Motesanib Axitinib Vatalanib Sunitinib Semaxanib Bosutinib Dasatinib Imatinib Nilotinib Sora... |
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map04972
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Pancreatic secretion |
The pancreas performs both exocrine and endocrine functions. The exocrine pancreas consists of two p... |
C01330 (Sodium cation) C00698 (Cl-) C00238 (Potassium cation) C01330 (Sodium cation) C01245 (D-myo-I... |
...inar cell CCKAR NKCC1 PLC PMCA DAG PKC Ach KCNQ1 MaxiK Acidic organelles Calcium signaling pathway A... |
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map04970
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Salivary secretion |
Saliva has manifold functions in maintaining the integrity of the oral tissues, in protecting teeth ... |
C00001 (H2O) C01330 (Sodium cation) C00698 (Cl-) C00698 (Cl-) C00238 (Potassium cation) C01330 (Sodi... |
... of electrolytes, water, and proteins MUC5B MUC7 MaxiK Tight junction Tight junction Endoplasmic ret... |