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map04928
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Parathyroid hormone synthesis, secretion and action |
Parathyroid hormone (PTH) is a key regulator of calcium and phosphorus homeostasis. The principal re... |
...2 (PRKCB), K19663 (PRKCG) K04630 (GNAI) K07763 (MMP14), K07995 (MMP15), K07996 (MMP16), K07997 (MMP1... |
...osis c-fos αNAC αNAC JunD Bglap2 Lrp6 cbfα/runt MMP13 c-fos Npt2a 3Na 25(OH)D 1,25(OH) 1,24,25(OH) (... |
map04657
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IL-17 signaling pathway |
The interleukin 17 (IL-17) family, a subset of cytokines consisting of IL-17A-F, plays crucial roles... |
...100 (DEFB4) K13908 (MUC5) K01403 (MMP9) K07994 (MMP13) K05430 (IL4) K05428 (IL5) K05435 (IL13) K2108... |
...D DNA CXCL1 CCL2 CCL7 CCL20 defensin MUC5 MMP9 MMP13 IL-4 IL-5 IL-13 TARC Th17 cell differentiation... |
map04926
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Relaxin signaling pathway |
Human relaxin-2 ("relaxin"), originally identified as a peptidic hormone of pregnancy, is now known ... |
...(COL1A), K19720 (COL3A), K06237 (COL4A) K01388 (MMP1) K01398 (MMP2) K01403 (MMP9) K07994 (MMP13) K04... |
...sodilator mechanisms) TGFβ pSmad2 αSMA Collagen MMP1 MMP2 MMP9 MMP13 Anti-fibrosis RXFP2 Gβγ INSL3 G... |
map05417
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Lipid and atherosclerosis |
Atherosclerosis is a chronic inflammatory disease marked by a narrowing of the arteries from lipid-r... |
...1 (ERK) K12330 (ARHGEF1) K17388 (ROCK2) K01388 (MMP1) K04513 (RHOA) K04456 (AKT) K00922 (PIK3CA_B_D)... |
...Calcium signaling pathway Ras ERK ARHGEF1 ROCK2 MMP1 Rho PIP AKT PI3K BAD Bcl-xL Bcl-2 Fluid shear s... |
map04668
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TNF signaling pathway |
Tumor necrosis factor (TNF), as a critical cytokine, can induce a wide range of intracellular signal... |
...9028 (JUNB) K01394 (MMP3) K01403 (MMP9) K07763 (MMP14) K16366 (EDN1) K05449 (VEGFC_D) K10165 (NOD2) ... |
...ocs3 Tnfaip3 Traf1 Ifi47 Fos Jun JunB Mmp3 Mmp9 Mmp14 Edn1 Vegfc Nod2 Icam1 Sele Vcam1 Ptgs2 Leukocy... |
map05206
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MicroRNAs in cancer |
MicroRNA (miRNA) is a cluster of small non-encoding RNA molecules of 21 - 23 nucleotides in length, ... |
...NOTCH4) K11459 (PCGF4) K17012 (MIR146A) K07996 (MMP16) K16863 (MIR21) K16866 (TIMP3) K17461 (RECK) K... |
...miR-34a miR-128 EGFR IRS-2 Notch Bmi-1 miR-146a MMP16 miR-21 TIMP3 RECK Colorectal cancer Glioma Pro... |
map05323
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Rheumatoid arthritis |
Rheumatoid arthritis (RA) is a chronic autoimmune joint disease where persistent inflammation affect... |
...05427 (CSF2) K05405 (IL6) K04519 (IL1B) K01388 (MMP1), K01394 (MMP3) K01365 (CTSL) K05433 (IL15) K06... |
...l TGFβ LTβ B cell IL11 MCSF IFNγ GMCSF IL6 IL1β MMP1/3 CTSL IL15 Inflammation Joint destruction Auto... |
map03320
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PPAR signaling pathway |
Peroxisome proliferator-activated receptors (PPARs) are nuclear hormone receptors that are activated... |
...C27A1_4) K01641 (HMGCS) K06086 (SORBS1) K01388 (MMP1) K08753 (FABP4) K08767 (ANGPTL4) K00232 (E1.3.3... |
Unsaturated fatty acid Unsaturated fatty acid Saturated fatty acid Eicosanoid Fibrate drug NSAID 9-c... |
map04912
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GnRH signaling pathway |
Gonadotropin-releasing hormone (GnRH) secretion from the hypothalamus acts upon its receptor in the ... |
...83 (CALM) K04634 (GNAQ), K04635 (GNA11) K07763 (MMP14) K04280 (GNRHR) K01115 (PLD1_2) K04632 (GNAS) ... |
PKC αGSU LHβ PA, PE DAG PLCβ CDC42 cAMP CREB CaMK MKK3/6 p38MAPK MEKK BMK PLA2 IP3R CaM q/11 MT1 GnR... |
map05171
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Coronavirus disease - COVID-19 |
Coronavirus disease of 2019 (COVID-19) is a highly contagious respiratory infection that is caused b... |
...6 (IL12A), K05425 (IL12B) K01394 (MMP3) K01388 (MMP1) K14624 (CCL2) K10030 (IL8) K25013 (nsp3) K2501... |
ACE2 Angiotensin II Angiotensin (1-7) AT1R MAS1 CORONAVIRUS DISEASE - COVID-19 Vascular smooth mu... |
map05200
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Pathways in cancer |
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...(VEGFB), K16859 (PGF), K05449 (VEGFC_D) K01388 (MMP1), K01398 (MMP2), K01403 (MMP9) K10030 (IL8) K04... |
PATHWAYS IN CANCER DCC CASP3 CASP9 CASP3 ECAD β-catenin Wnt α-catenin β-catenin ITGB Dvl ECM ITGA ... |
map05219
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Bladder cancer |
The urothelium covers the luminal surface of almost the entire urinary tract, extending from the ren... |
K02833 (HRAS) K01388 (MMP1), K01398 (MMP2), K01403 (MMP9) K00758 (deoA) K05448 (VEGFA) K10030 (IL8) ... |
Adherens junction H-Ras VEGF signaling pathway ErbB signaling pathway MMPs VEGF IL-8 TSP-1 EGFR E-ca... |