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Usage : dbname:identifier

KEGG   COMPOUND: C00304
Entry
C00304                      Compound                               
Name
Kanamycin
Formula
C18H33N3O10(R1)(R2)
Structure
Remark
ATC code: A07AA08 J01GB04 S01AA24
Drug group: DG00085
Comment
Comprised of three components, Kanamycin A [CPD:C01822], the major component (usually designated as Kanamycin), Kanamycin B [CPD:C00825] and Kanamycin C [CPD:C01823].
Brite
Compounds with biological roles [BR:br08001]
 Antibiotics
  Aminoglycosides
   2-Deoxystreptamines
    C00304  Kanamycin
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07A INTESTINAL ANTIINFECTIVES
    A07AA Antibiotics
     A07AA08 Kanamycin
      C00304  Kanamycin
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB04 Kanamycin
      C00304  Kanamycin
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA24 Kanamycin
      C00304  Kanamycin
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00085  Kanamycin
    C00304  Kanamycin
  DG01966  Antitubercular
   DG00085  Kanamycin
    C00304  Kanamycin
Other DBs
CAS: 8063-07-8
PubChem: 3598
ChEBI: 6104
LinkDB
KCF data

ATOM        33
            1   O2a O    27.8437  -15.0357
            2   C1y C    29.0329  -14.3361
            3   O2x O    30.2921  -15.0357
            4   C1y C    31.4814  -14.3361
            5   C1y C    31.4814  -12.9370
            6   C1y C    30.2921  -12.2374
            7   C1y C    29.0329  -12.9370
            8   C1b C    32.7406  -15.0357
            9   Z   R#   32.7406  -16.4348
            10  Z   R#   27.8437  -12.2374
            11  C1y C    27.9136  -16.4348
            12  C1y C    29.1029  -17.1344
            13  C1x C    29.1029  -18.5335
            14  C1y C    27.9136  -19.2331
            15  C1y C    26.6544  -18.5335
            16  C1y C    26.6544  -17.1344
            17  N1a N    30.2921  -16.4348
            18  N1a N    27.9136  -20.6322
            19  O1a O    25.4652  -16.5048
            20  O2a O    25.5351  -19.3030
            21  C1y C    24.2759  -20.0026
            22  C1y C    24.2759  -21.4017
            23  C1y C    23.0866  -22.1013
            24  C1y C    21.8974  -21.4017
            25  C1y C    21.8974  -20.0026
            26  O2x O    23.0866  -19.3030
            27  O1a O    25.5351  -22.1013
            28  O1a O    20.6382  -22.1013
            29  C1b C    20.6382  -19.3030
            30  N1a N    23.0866  -23.5004
            31  O1a O    19.4489  -20.0026
            32  O1a O    30.2222  -10.8383
            33  O1a O    32.6707  -12.2374
BOND        35
            1    16  19 1 #Up
            2     8   9 1
            3    15  20 1 #Down
            4    11   1 1 #Down
            5    21  20 1 #Down
            6     7  10 1 #Down
            7     2   3 1
            8     3   4 1
            9     4   5 1
            10    5   6 1
            11   21  22 1
            12   22  23 1
            13   23  24 1
            14   24  25 1
            15   25  26 1
            16   26  21 1
            17    6   7 1
            18   22  27 1 #Down
            19    7   2 1
            20   24  28 1 #Down
            21   11  12 1
            22   25  29 1 #Up
            23   12  13 1
            24   23  30 1 #Up
            25   13  14 1
            26   29  31 1
            27   14  15 1
            28    6  32 1 #Up
            29   15  16 1
            30    5  33 1 #Down
            31   16  11 1
            32    2   1 1 #Down
            33   12  17 1 #Up
            34    4   8 1 #Up
            35   14  18 1 #Up

» Japanese version

KEGG   DRUG: Tobramycin
Entry
D00063                      Drug                                   
Name
Tobramycin (JP18/USP);
Tobi (TN);
Tobracin (TN);
Tobrex (TN);
Bethkis (TN)
Product
BETHKIS (Chiesi USA), KITABIS PAK (Pari Respiratory Equipment), TOBI (Mylan Specialty L.P.), TOBI PODHALER (Mylan Specialty L.P.), TOBREX (Novartis Pharmaceuticals Corporation)
  Generic
TOBRAMYCIN (A-S Medication Solutions), TOBRAMYCIN (A-S Medication Solutions), TOBRAMYCIN (Advanced Rx Pharmacy of Tennessee), TOBRAMYCIN (Amneal Pharmaceuticals LLC), TOBRAMYCIN (Ascend Laboratories), TOBRAMYCIN (Asclemed USA), TOBRAMYCIN (Asclemed USA), TOBRAMYCIN (Aurobindo Pharma Limited), TOBRAMYCIN (Bausch & Lomb Incorporated), TOBRAMYCIN (Belcher Pharmaceuticals), TOBRAMYCIN (DirectRX), TOBRAMYCIN (FOSUN PHARMA USA), TOBRAMYCIN (Genericus), TOBRAMYCIN (Gland Pharma Limited), TOBRAMYCIN (Lifestar Pharma LLC), TOBRAMYCIN (Lifestar Pharma LLC), TOBRAMYCIN (Lupin Pharmaceuticals), TOBRAMYCIN (Medsource Pharmaceuticals), TOBRAMYCIN (Micro Labs Limited), TOBRAMYCIN (NuCare Pharmaceuticals), TOBRAMYCIN (NuCare Pharmaceuticals), TOBRAMYCIN (Preferred Pharmaceuticals), TOBRAMYCIN (Preferred Pharmaceuticals), TOBRAMYCIN (Proficient Rx LP), TOBRAMYCIN (Proficient Rx LP), TOBRAMYCIN (Proficient Rx LP), TOBRAMYCIN (Proficient Rx LP), TOBRAMYCIN (Quality Care Products), TOBRAMYCIN (REMEDYREPACK), TOBRAMYCIN (REMEDYREPACK), TOBRAMYCIN (RPK Pharmaceuticals), TOBRAMYCIN (RPK Pharmaceuticals), TOBRAMYCIN (Sandoz), TOBRAMYCIN (Slate Run Pharmaceuticals), TOBRAMYCIN (Somerset Therapeutics), TOBRAMYCIN (Sun Pharmaceutical Industries), TOBRAMYCIN (Teva Pharmaceuticals USA), TOBRAMYCIN (Teva Pharmaceuticals USA), TOBRAMYCIN INHALATION (Prasco), TOBRAMYCIN INHALATION SOLUTION (Dr. Reddy's Laboratories), TOBRAMYCIN INHALATION SOLUTION (NorthStar RxLLC), TOBRAMYCIN OPHTHALMIC SOLUTION (Alembic Pharmaceuticals)
Formula
C18H37N5O9
Exact mass
467.2591
Mol weight
467.5145
Structure
Simcomp
Source
Streptomyces tenebrarius [TAX:1933]
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
Same as: C00397
Therapeutic category: 1317 6123
ATC code: J01GB01 S01AA12
Chemical structure group: DG00608
Product (DG00608): D00063<JP/US> D02542<US>
Product (mixture): D11178<US> D12133<US>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
  Disease
Cystic fibrosis patients with Pseudomonas aeruginosa [DS:H00218]
Target
50S ribosomal subunit
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Biosynthesis
map00524  Neomycin, kanamycin and gentamicin biosynthesis
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB01 Tobramycin
      D00063  Tobramycin (JP18/USP) <JP/US>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA12 Tobramycin
      D00063  Tobramycin (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
 Antibacterials
  Aminoglycosides
   Tobramycin
    D00063  Tobramycin (JP18/USP)
 Ophthalmic Agents
  Ophthalmic Anti-Infectives
   Antibacterials, Ophthalmic
    Tobramycin
     D00063  Tobramycin (JP18/USP)
 Respiratory Tract/Pulmonary Agents
  Cystic Fibrosis Agents
   Inhaled Anti-infectives
    Tobramycin
     D00063  Tobramycin (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   131  Ophthalmic agents
    1317  Ophthalmic antibiotics
     D00063  Tobramycin (JP18/USP)
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   612  Acting mainly on gram-negative bacteria
    6123  Amino sugars
     D00063  Tobramycin (JP18/USP)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00608  Tobramycin
    D00063  Tobramycin
Drug classes [BR:br08332]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   D00063  Tobramycin
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D00063  Tobramycin (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00063  Tobramycin
  D00063 Tobramycin injection
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D00063
Pharmacogenomic biomarkers [br08341.html]
 Polymorphisms and mutations affecting drug response
  D00063
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00608  Tobramycin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00608  Tobramycin
Other DBs
CAS: 32986-56-4
PubChem: 7847131
ChEBI: 28864
PDB-CCD: TOY[PDBj]
LigandBox: D00063
NIKKAJI: J4.533K
LinkDB
KCF data

ATOM        32
            1   C1y C    20.6560  -20.0968
            2   C1y C    20.6560  -21.4973
            3   C1y C    21.8689  -22.1975
            4   C1y C    23.0818  -21.4973
            5   C1y C    23.0818  -20.0968
            6   O2x O    21.8689  -19.3965
            7   C1b C    19.4432  -19.3965
            8   O1a O    18.2473  -20.0872
            9   O1a O    19.4432  -22.1975
            10  N1a N    21.8689  -23.5978
            11  O1a O    24.3134  -22.2085
            12  O2a O    24.3134  -19.3855
            13  C1y C    25.4878  -18.6963
            14  C1y C    26.7056  -19.3879
            15  C1x C    27.9134  -18.6791
            16  C1y C    27.9035  -17.2786
            17  C1y C    26.6857  -16.5869
            18  C1y C    25.4779  -17.2958
            19  N1a N    26.7157  -20.7965
            20  N1a N    29.0779  -16.5893
            21  O1a O    24.2675  -16.6084
            22  O2a O    26.6757  -15.1950
            23  C1y C    27.8854  -14.4851
            24  O2x O    29.0946  -15.1718
            25  C1y C    30.3025  -14.4631
            26  C1y C    30.2926  -13.0626
            27  C1x C    29.0835  -12.3758
            28  C1y C    27.8755  -13.0846
            29  C1b C    31.5468  -15.1693
            30  N1a N    31.5569  -16.5953
            31  O1a O    31.5060  -12.3503
            32  N1a N    26.6567  -12.3923
BOND        34
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1 #Up
            8     7   8 1
            9     2   9 1 #Down
            10    3  10 1 #Up
            11    4  11 1 #Down
            12    5  12 1 #Down
            13   13  12 1 #Down
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   16  17 1
            18   17  18 1
            19   13  18 1
            20   14  19 1 #Up
            21   16  20 1 #Up
            22   18  21 1 #Up
            23   17  22 1 #Down
            24   23  22 1 #Down
            25   23  24 1
            26   24  25 1
            27   25  26 1
            28   26  27 1
            29   27  28 1
            30   23  28 1
            31   25  29 1 #Up
            32   29  30 1
            33   26  31 1 #Down
            34   28  32 1 #Down

» Japanese version   » Back

KEGG   DRUG: Amikacin sulfate
Entry
D00865                      Drug                                   
Name
Amikacin sulfate (JP18/USP);
Amikin (TN)
Product
ARIKAYCE (Insmed Incorporated)
  Generic
AMIKACIN SULFATE (Fresenius Kabi USA), AMIKACIN SULFATE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), AMIKACIN SULFATE (Heritage Pharmaceuticals Inc. d/b/a Avet Pharmaceuticals), AMIKACIN SULFATE (Hikma Pharmaceuticals USA), AMIKACIN SULFATE (Qilu Pharmaceutical), AMIKACIN SULFATE (Sagent Pharmaceuticals)
Formula
C22H43N5O13. 2H2SO4
Exact mass
781.2205
Mol weight
781.7595
Structure
Simcomp
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
Therapeutic category: 6123 6169
ATC code: D06AX12 J01GB06 S01AA21
Chemical structure group: DG00403
Product (DG00403): D00865<JP/US>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06A ANTIBIOTICS FOR TOPICAL USE
    D06AX Other antibiotics for topical use
     D06AX12 Amikacin
      D00865  Amikacin sulfate (JP18/USP) <JP/US>
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB06 Amikacin
      D00865  Amikacin sulfate (JP18/USP) <JP/US>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA21 Amikacin
      D00865  Amikacin sulfate (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
 Antibacterials
  Aminoglycosides
   Amikacin
    D00865  Amikacin sulfate (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   612  Acting mainly on gram-negative bacteria
    6123  Amino sugars
     D00865  Amikacin sulfate (JP18/USP)
   616  Acting mainly on acid-fast bacteria
    6169  Others
     D00865  Amikacin sulfate (JP18/USP)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00403  Amikacin
    D00865  Amikacin sulfate
Drug classes [BR:br08332]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   D00865  Amikacin sulfate
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D00865  Amikacin sulfate (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00865  Amikacin sulfate
  D00865  Amikacin sulfate injection
  D00865  Amikacin sulfate for injection
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D00865
New drug approvals in the USA, Europe and Japan [br08328.html]
 Approval dates by FDA, EMA and PMDA
  D00865
Pharmacogenomic biomarkers [br08341.html]
 Polymorphisms and mutations affecting drug response
  D00865
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00403  Amikacin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00403  Amikacin
Other DBs
CAS: 39831-55-5
PubChem: 7847930
ChEBI: 2638
LigandBox: D00865
NIKKAJI: J268.900F
LinkDB
KCF data

ATOM        50
            1   C1y C    11.5511  -20.1618
            2   C1y C    11.5511  -21.5619
            3   C1y C    12.7637  -22.2620
            4   C1y C    13.9763  -21.5619
            5   C1y C    13.9763  -20.1618
            6   O2x O    12.7637  -19.4617
            7   O2a O    15.2075  -19.4507
            8   C1y C    16.3816  -18.7617
            9   C1y C    17.5991  -19.4531
            10  C1x C    18.8066  -18.7445
            11  C1y C    18.7967  -17.3443
            12  C1y C    17.5792  -16.6529
            13  C1y C    16.3717  -17.3615
            14  O2a O    17.5692  -15.2613
            15  C1y C    18.7786  -14.5516
            16  C1b C    10.3386  -19.4617
            17  O1a O     9.1430  -20.1522
            18  O1a O    10.3386  -22.2620
            19  N1a N    12.7637  -23.6619
            20  O1a O    15.2075  -22.2730
            21  N1b N    17.5392  -20.8614
            22  C5a C    18.7842  -21.5619
            23  C1c C    19.9968  -20.8619
            24  C1b C    21.2093  -21.5619
            25  C1b C    22.4219  -20.8619
            26  N1a N    23.6345  -21.5619
            27  O2x O    19.9874  -15.2381
            28  C1y C    21.1950  -14.5296
            29  C1y C    21.1851  -13.1294
            30  C1y C    19.9763  -12.4429
            31  C1y C    18.7687  -13.1514
            32  C1b C    22.4391  -15.2356
            33  N1a N    22.4492  -16.6613
            34  O1a O    22.3983  -12.4174
            35  O1a O    19.9662  -11.0610
            36  O1a O    17.5502  -12.4594
            37  O5a O    18.7920  -22.9618
            38  O1a O    19.9968  -19.4619
            39  N1a N    19.9707  -16.6553
            40  O1a O    15.1617  -16.6744
            41  S4a S    29.6828  -18.0616
            42  O1d O    29.6828  -19.4617
            43  O1d O    29.6828  -16.6615
            44  O1d O    31.0830  -18.0616
            45  O1d O    28.2827  -18.0616
            46  S4a S    29.6828  -18.0616
            47  O1d O    29.6828  -19.4617
            48  O1d O    29.6828  -16.6615
            49  O1d O    31.0830  -18.0616
            50  O1d O    28.2827  -18.0616
BOND        50
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     5   7 1 #Down
            8     8   7 1 #Down
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14    8  13 1
            15   12  14 1 #Down
            16   15  14 1 #Down
            17    1  16 1 #Up
            18   16  17 1
            19    2  18 1 #Down
            20    3  19 1 #Up
            21    4  20 1 #Down
            22    9  21 1 #Up
            23   21  22 1
            24   22  23 1
            25   23  24 1
            26   24  25 1
            27   25  26 1
            28   15  27 1
            29   27  28 1
            30   28  29 1
            31   29  30 1
            32   30  31 1
            33   15  31 1
            34   28  32 1 #Up
            35   32  33 1
            36   29  34 1 #Down
            37   30  35 1 #Up
            38   31  36 1 #Down
            39   22  37 2
            40   23  38 1 #Up
            41   11  39 1 #Up
            42   13  40 1 #Up
            43   41  42 2
            44   41  43 2
            45   41  44 1
            46   41  45 1
            47   46  47 2
            48   46  48 2
            49   46  49 1
            50   46  50 1
BRACKET     1    26.8800  -20.0200   26.8800  -15.8900
            1    32.5500  -15.8900   32.5500  -20.0200
            1  2
 ORIGINAL  1   41  42  43  44  45
 REPEAT    1   46  47  48  49  50

» Japanese version   » Back

KEGG   DRUG: Kanamycin sulfate
Entry
D00866                      Drug                                   
Name
Kanamycin sulfate (USP);
Kanamycin monosulfate (JP18);
Kantrex (TN)
Formula
C18H36N4O11. H2SO4
Exact mass
582.2054
Mol weight
582.5771
Structure
Simcomp
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
 DG01966  Antitubercular
Remark
Same as: C08046
Therapeutic category: 6123
ATC code: A07AA08 J01GB04 S01AA24
Chemical structure group: DG00085
Product (DG00085): D00866<JP> D03262<JP>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07A INTESTINAL ANTIINFECTIVES
    A07AA Antibiotics
     A07AA08 Kanamycin
      D00866  Kanamycin sulfate (USP) <JP>
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB04 Kanamycin
      D00866  Kanamycin sulfate (USP) <JP>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA24 Kanamycin
      D00866  Kanamycin sulfate (USP) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   612  Acting mainly on gram-negative bacteria
    6123  Amino sugars
     D00866  Kanamycin sulfate (USP); Kanamycin monosulfate (JP18)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00085  Kanamycin
    D00866  Kanamycin sulfate
  DG01966  Antitubercular
   DG00085  Kanamycin
    D00866  Kanamycin sulfate
Drug classes [BR:br08332]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   D00866  Kanamycin sulfate
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D00866  Kanamycin sulfate (USP) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00866  Kanamycin monosulfate
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00085  Kanamycin
  DG01966  Antitubercular
   DG00085  Kanamycin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00085  Kanamycin
Other DBs
CAS: 25389-94-0
PubChem: 7847931
ChEBI: 6109
LigandBox: D00866
NIKKAJI: J203.663K
LinkDB
KCF data

ATOM        38
            1   O2a O    30.3297  -15.0547
            2   C1y C    31.4689  -14.3495
            3   O2x O    32.7495  -15.0399
            4   C1y C    33.9585  -14.3345
            5   C1y C    33.9489  -12.9339
            6   C1y C    32.7300  -12.2384
            7   C1y C    31.5210  -12.9506
            8   C1b C    35.1773  -15.0231
            9   N1a N    35.1870  -16.4237
            10  O1a O    30.3001  -12.2587
            11  C1y C    30.3489  -16.4552
            12  C1y C    31.5722  -17.1430
            13  C1x C    31.5892  -18.5461
            14  C1y C    30.3866  -19.2553
            15  C1y C    29.0934  -18.5746
            16  C1y C    29.1429  -17.1777
            17  N1a N    32.7772  -16.4238
            18  N1a N    30.4040  -20.6561
            19  O1a O    27.9260  -16.4914
            20  O2a O    27.9663  -19.2884
            21  C1y C    26.7575  -19.9994
            22  C1y C    26.7664  -21.3994
            23  C1y C    25.5576  -22.1034
            24  C1y C    24.3398  -21.4147
            25  C1y C    24.3310  -20.0148
            26  O2x O    25.5399  -19.3036
            27  O1a O    27.9848  -22.0884
            28  O1a O    23.1303  -22.1191
            29  C1b C    23.1127  -19.3187
            30  N1a N    25.5664  -23.5041
            31  O1a O    21.9030  -20.0302
            32  O1a O    32.7204  -10.8376
            33  O1a O    35.1581  -12.2217
            34  O1d O    33.6899  -21.5139
            35  S4a S    35.0836  -21.5139
            36  O1d O    35.0765  -22.9076
            37  O1d O    36.4773  -21.5139
            38  O1d O    35.0765  -20.1202
BOND        39
            1    16  19 1 #Up
            2     8   9 1
            3    15  20 1 #Down
            4    11   1 1 #Down
            5    21  20 1 #Down
            6     7  10 1 #Down
            7     2   3 1
            8     3   4 1
            9     4   5 1
            10    5   6 1
            11   21  22 1
            12   22  23 1
            13   23  24 1
            14   24  25 1
            15   25  26 1
            16   26  21 1
            17    6   7 1
            18   22  27 1 #Down
            19    7   2 1
            20   24  28 1 #Down
            21   11  12 1
            22   25  29 1 #Up
            23   12  13 1
            24   23  30 1 #Up
            25   13  14 1
            26   29  31 1
            27   14  15 1
            28    6  32 1 #Up
            29   15  16 1
            30    5  33 1 #Down
            31   16  11 1
            32    2   1 1 #Down
            33   12  17 1 #Up
            34    4   8 1 #Up
            35   14  18 1 #Up
            36   34  35 1
            37   35  36 2
            38   35  37 1
            39   35  38 2

» Japanese version   » Back

KEGG   DRUG: Netilmicin sulfate
Entry
D00867                      Drug                                   
Name
Netilmicin sulfate (JAN/USP);
Netromycin (TN)
Formula
(C21H41N5O7)2. 5H2SO4
Exact mass
1440.4381
Mol weight
1441.5515
Structure
Simcomp
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
ATC code: J01GB07 S01AA23
Chemical structure group: DG00609
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB07 Netilmicin
      D00867  Netilmicin sulfate (JAN/USP)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA23 Netilmicin
      D00867  Netilmicin sulfate (JAN/USP)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00609  Netilmicin
    D00867  Netilmicin sulfate
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D00867  Netilmicin sulfate (JAN/USP)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00609  Netilmicin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00609  Netilmicin
Other DBs
CAS: 56391-57-2
PubChem: 7847932
ChEBI: 7529
LigandBox: D00867
NIKKAJI: J245.492K
LinkDB
KCF data

ATOM        91
            1   S4a S    24.4727   -9.7043
            2   O1d O    23.0724   -9.6968
            3   O1d O    25.8729   -9.7043
            4   O1d O    24.4653   -8.3112
            5   O1d O    24.4653  -11.1044
            6   C1y C    10.9621  -10.1542
            7   C1y C    12.1675  -10.8621
            8   C1y C    10.9681   -8.7558
            9   O2a O     9.7453  -10.8329
            10  C1x C    13.3844  -10.1716
            11  N1b N    12.1558  -12.2720
            12  C1y C    12.1850   -8.0597
            13  O1a O     9.7628   -8.0480
            14  C1y C     8.5342  -11.5408
            15  C1y C    13.3785   -8.7735
            16  C1b C    13.3551  -12.9801
            17  O2a O    12.2143   -6.6612
            18  C1y C     8.5400  -12.9391
            19  O2x O     7.3172  -10.8387
            20  N1a N    14.7300   -8.4048
            21  C1a C    13.3435  -14.3725
            22  C1y C    13.4312   -5.9711
            23  C1y C     7.3289  -13.6410
            24  O1a O     9.7570  -13.6293
            25  C1x C     6.1003  -11.5525
            26  O2x O    14.6422   -6.6612
            27  C1y C    13.4312   -4.5669
            28  C1z C     6.1063  -12.9506
            29  N1b N     7.3466  -15.0395
            30  C2y C    15.8534   -5.9711
            31  C1x C    14.6422   -3.8648
            32  N1a N    12.2260   -3.8648
            33  C1a C     6.3460  -16.0281
            34  C2x C    15.8534   -4.5669
            35  C1b C    17.0762   -6.6612
            36  N1a N    17.0820   -8.0597
            37  C1a C     4.8896  -13.6642
            38  O1a O     4.8932  -12.2503
            39  S4a S    24.4727   -9.7043
            40  O1d O    23.0724   -9.6968
            41  O1d O    25.8729   -9.7043
            42  O1d O    24.4653   -8.3112
            43  O1d O    24.4653  -11.1044
            44  S4a S    24.4727   -9.7043
            45  O1d O    23.0724   -9.6968
            46  O1d O    25.8729   -9.7043
            47  O1d O    24.4653   -8.3112
            48  O1d O    24.4653  -11.1044
            49  S4a S    24.4727   -9.7043
            50  O1d O    23.0724   -9.6968
            51  O1d O    25.8729   -9.7043
            52  O1d O    24.4653   -8.3112
            53  O1d O    24.4653  -11.1044
            54  S4a S    24.4727   -9.7043
            55  O1d O    23.0724   -9.6968
            56  O1d O    25.8729   -9.7043
            57  O1d O    24.4653   -8.3112
            58  O1d O    24.4653  -11.1044
            59  C1y C    10.9621  -10.1542
            60  C1y C    12.1675  -10.8621
            61  C1x C    13.3844  -10.1716
            62  C1y C    13.3785   -8.7735
            63  N1a N    14.7300   -8.4048
            64  C1y C    12.1850   -8.0597
            65  C1y C    10.9681   -8.7558
            66  O1a O     9.7628   -8.0480
            67  O2a O    12.2143   -6.6612
            68  C1y C    13.4312   -5.9711
            69  O2x O    14.6422   -6.6612
            70  C2y C    15.8534   -5.9711
            71  C2x C    15.8534   -4.5669
            72  C1x C    14.6422   -3.8648
            73  C1y C    13.4312   -4.5669
            74  N1a N    12.2260   -3.8648
            75  C1b C    17.0762   -6.6612
            76  N1a N    17.0820   -8.0597
            77  N1b N    12.1558  -12.2720
            78  C1b C    13.3551  -12.9801
            79  C1a C    13.3435  -14.3725
            80  O2a O     9.7453  -10.8329
            81  C1y C     8.5342  -11.5408
            82  C1y C     8.5400  -12.9391
            83  C1y C     7.3289  -13.6410
            84  C1z C     6.1063  -12.9506
            85  C1x C     6.1003  -11.5525
            86  O2x O     7.3172  -10.8387
            87  C1a C     4.8896  -13.6642
            88  O1a O     4.8932  -12.2503
            89  N1b N     7.3466  -15.0395
            90  C1a C     6.3460  -16.0281
            91  O1a O     9.7570  -13.6293
BOND        90
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     1   5 2
            5    39  40 1
            6    39  41 1
            7    39  42 2
            8    39  43 2
            9    44  45 1
            10   44  46 1
            11   44  47 2
            12   44  48 2
            13   49  50 1
            14   49  51 1
            15   49  52 2
            16   49  53 2
            17   54  55 1
            18   54  56 1
            19   54  57 2
            20   54  58 2
            21    6   7 1
            22    6   8 1
            23    6   9 1 #Down
            24    7  10 1
            25    7  11 1 #Up
            26    8  12 1
            27    8  13 1 #Up
            28   14   9 1 #Down
            29   10  15 1
            30   11  16 1
            31   12  17 1 #Down
            32   14  18 1
            33   14  19 1
            34   15  20 1 #Up
            35   16  21 1
            36   22  17 1 #Down
            37   18  23 1
            38   18  24 1 #Down
            39   19  25 1
            40   22  26 1
            41   22  27 1
            42   23  28 1
            43   23  29 1 #Up
            44   26  30 1
            45   27  31 1
            46   27  32 1 #Down
            47   29  33 1
            48   30  34 2
            49   30  35 1
            50   35  36 1
            51   12  15 1
            52   25  28 1
            53   31  34 1
            54   28  37 1
            55   28  38 1 #Up
            56   59  60 1
            57   59  65 1
            58   59  80 1 #Down
            59   60  61 1
            60   60  77 1 #Up
            61   65  64 1
            62   65  66 1 #Up
            63   81  80 1 #Down
            64   61  62 1
            65   77  78 1
            66   64  67 1 #Down
            67   81  82 1
            68   81  86 1
            69   62  63 1 #Up
            70   78  79 1
            71   68  67 1 #Down
            72   82  83 1
            73   82  91 1 #Down
            74   86  85 1
            75   68  69 1
            76   68  73 1
            77   83  84 1
            78   83  89 1 #Up
            79   69  70 1
            80   73  72 1
            81   73  74 1 #Down
            82   89  90 1
            83   70  71 2
            84   70  75 1
            85   75  76 1
            86   64  62 1
            87   85  84 1
            88   72  71 1
            89   84  87 1
            90   84  88 1 #Up
BRACKET     1    21.7000  -12.1100   21.7000   -7.4200
            1    27.1600   -7.4200   27.1600  -12.1100
            1  5
 ORIGINAL  1    1   2   3   4   5
 REPEAT    1   39  40  41  42  43  44  45  46  47  48  49  50  51  52  53  54
            1   55  56  57  58
            2     2.5200  -17.0100    2.5200   -2.5900
            2    19.1800   -2.5900   19.1800  -17.0100
            2  2
 ORIGINAL  2    6   7  10  15  20  12   8  13  17  22  26  30  34  31  27  32
            2   35  36  11  16  21   9  14  18  23  28  25  19  37  38  29  33
            2   24
 REPEAT    2   59  60  61  62  63  64  65  66  67  68  69  70  71  72  73  74
            2   75  76  77  78  79  80  81  82  83  84  85  86  87  88  89  90
            2   91

» Japanese version   » Back

KEGG   DRUG: Gentamicin sulfate
Entry
D01063                      Drug                                   
Name
Gentamicin sulfate (JP18/USP);
Garamycin (TN);
Gentacin (TN)
Product
  Generic
GENTAK (Proficient Rx LP), GENTAMICIN (Eugia US LLC), GENTAMICIN (Eugia US LLC), GENTAMICIN (Fresenius Kabi USA), GENTAMICIN (Fresenius Kabi USA), GENTAMICIN (Fresenius Kabi USA), GENTAMICIN (Fresenius Kabi USA), GENTAMICIN (Fresenius Kabi USA), GENTAMICIN (Fresenius Kabi USA), GENTAMICIN (HF Acquisition Co LLC), GENTAMICIN (Henry Schein), GENTAMICIN (Hikma Pharmaceuticals USA), GENTAMICIN (Medical Purchasing Solutions), GENTAMICIN (REMEDYREPACK), GENTAMICIN SULFATE (A-S Medication Solutions), GENTAMICIN SULFATE (A-S Medication Solutions), GENTAMICIN SULFATE (Asclemed USA), GENTAMICIN SULFATE (Asclemed USA), GENTAMICIN SULFATE (Bausch & Lomb Incorporated), GENTAMICIN SULFATE (Cardinal Health 107), GENTAMICIN SULFATE (Cosette Pharmaceuticals), GENTAMICIN SULFATE (Cosette Pharmaceuticals), GENTAMICIN SULFATE (DIRECT RX), GENTAMICIN SULFATE (HF Acquisition Co LLC), GENTAMICIN SULFATE (Henry Schein), GENTAMICIN SULFATE (Hospira), GENTAMICIN SULFATE (Medical Purchasing Solutions), GENTAMICIN SULFATE (Medsource Pharmaceuticals), GENTAMICIN SULFATE (NuCare Pharmaceuticals), GENTAMICIN SULFATE (NuCare Pharmaceuticals), GENTAMICIN SULFATE (Pacific Pharma), GENTAMICIN SULFATE (Padagis Israel Pharmaceuticals), GENTAMICIN SULFATE (Padagis Israel Pharmaceuticals), GENTAMICIN SULFATE (Preferred Pharmaceuticals), GENTAMICIN SULFATE (Preferred Pharmaceuticals), GENTAMICIN SULFATE (Proficient Rx LP), GENTAMICIN SULFATE (Proficient Rx LP), GENTAMICIN SULFATE (Proficient Rx LP), GENTAMICIN SULFATE (Proficient Rx LP), GENTAMICIN SULFATE (Proficient Rx LP), GENTAMICIN SULFATE (REMEDYREPACK), GENTAMICIN SULFATE (REMEDYREPACK), GENTAMICIN SULFATE (RPK Pharmaceuticals), GENTAMICIN SULFATE (RPK Pharmaceuticals), GENTAMICIN SULFATE (Sandoz), GENTAMICIN SULFATE IN SODIUM CHLORIDE (Baxter Healthcare Corporation), GENTAMICIN SULFATE OPTH SOLUTION (Direct_Rx)
Formula
C19H37N5O7(R1)(R2). H2SO4
Structure
Simcomp
Source
Micromonospora purpurea [TAX:1877]
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
Same as: C11334
Therapeutic category: 1317 2634 6134
ATC code: D06AX07 J01GB03 S01AA11 S02AA14 S03AA06
Chemical structure group: DG00401
Product (DG00401): D01063<JP/US>
Product (mixture): D04773<JP>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
  Disease
Bacterial endocarditis [DS:H00334]
Comment
R1,R2: See Gentamicin C [CPD:C01918]
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06A ANTIBIOTICS FOR TOPICAL USE
    D06AX Other antibiotics for topical use
     D06AX07 Gentamicin
      D01063  Gentamicin sulfate (JP18/USP) <JP/US>
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB03 Gentamicin
      D01063  Gentamicin sulfate (JP18/USP) <JP/US>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA11 Gentamicin
      D01063  Gentamicin sulfate (JP18/USP) <JP/US>
  S02 OTOLOGICALS
   S02A ANTIINFECTIVES
    S02AA Antiinfectives
     S02AA14 Gentamicin
      D01063  Gentamicin sulfate (JP18/USP) <JP/US>
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03A ANTIINFECTIVES
    S03AA Antiinfectives
     S03AA06 Gentamicin
      D01063  Gentamicin sulfate (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
 Antibacterials
  Aminoglycosides
   Gentamicin
    D01063  Gentamicin sulfate (JP18/USP)
 Dermatological Agents
  Topical Anti-infectives
   Antibacterials, dermatological
    Gentamicin
     D01063  Gentamicin sulfate (JP18/USP)
 Ophthalmic Agents
  Ophthalmic Anti-Infectives
   Antibacterials, Ophthalmic
    Gentamicin
     D01063  Gentamicin sulfate (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   131  Ophthalmic agents
    1317  Ophthalmic antibiotics
     D01063  Gentamicin sulfate (JP18/USP)
 2  Agents affecting individual organs
  26  Epidermides
   263  Suppurative dermatosis agents
    2634  Antibiotics for external use
     D01063  Gentamicin sulfate (JP18/USP)
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6134  Amino sugars
     D01063  Gentamicin sulfate (JP18/USP)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00401  Gentamicin
    D01063  Gentamicin sulfate
Drug classes [BR:br08332]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   D01063  Gentamicin sulfate
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D01063  Gentamicin sulfate (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01063  Gentamicin sulfate
  D01063  Gentamicin sulfate injection
  D01063  Gentamicin sulfate ophthalmic solution
  D01063  Gentamicin sulfate ointment
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00401  Gentamicin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00401  Gentamicin
Other DBs
CAS: 1405-41-0
PubChem: 7848126
ChEBI: 5312
NIKKAJI: J399.179B
LinkDB
KCF data

ATOM        38
            1   S4a S    53.5166  -22.8214
            2   O1d O    53.5166  -21.4177
            3   O1d O    53.5166  -24.1551
            4   O1d O    54.9203  -22.8214
            5   O1d O    52.1830  -22.8214
            6   C1x C    38.9466  -19.9619
            7   C1z C    38.9466  -21.3632
            8   C1y C    40.1600  -22.0639
            9   C1y C    41.3736  -21.3632
            10  C1y C    41.3736  -19.9619
            11  O2x O    40.1600  -19.2614
            12  O2a O    42.6058  -19.2504
            13  C1y C    43.8193  -18.5497
            14  C1y C    45.0612  -19.2669
            15  C1x C    46.2748  -18.5664
            16  C1y C    46.2750  -17.1651
            17  C1y C    45.0331  -16.4480
            18  C1y C    43.8195  -17.1484
            19  O1a O    42.6058  -22.0749
            20  C1a C    38.5840  -22.7167
            21  O1a O    37.5453  -21.3632
            22  N1b N    40.1600  -23.4649
            23  C1a C    38.9298  -24.1754
            24  N1a N    45.0610  -20.6625
            25  O1a O    42.6345  -16.4639
            26  N1a N    47.5120  -16.4509
            27  O2a O    45.0333  -15.0576
            28  C1y C    46.2535  -14.3534
            29  O2x O    47.4531  -15.0464
            30  C1y C    48.6668  -14.3461
            31  C1x C    48.6671  -12.9449
            32  C1x C    47.4675  -12.2519
            33  C1y C    46.2538  -12.9521
            34  C1c C    49.8987  -15.0577
            35  Z   R#   51.0955  -14.3670
            36  N1b N    49.8984  -16.4586
            37  Z   R#   51.0952  -17.1500
            38  N1a N    45.0266  -12.2431
BOND        39
            1     1   2 2
            2     1   3 2
            3     1   4 1
            4     1   5 1
            5     6   7 1
            6     7   8 1
            7     8   9 1
            8     9  10 1
            9    10  11 1
            10    6  11 1
            11   10  12 1 #Down
            12   13  12 1 #Down
            13   13  14 1
            14   14  15 1
            15   15  16 1
            16   16  17 1
            17   17  18 1
            18   13  18 1
            19    9  19 1 #Down
            20    7  20 1 #Down
            21    7  21 1 #Up
            22    8  22 1 #Up
            23   22  23 1
            24   14  24 1 #Up
            25   18  25 1 #Up
            26   16  26 1 #Up
            27   17  27 1 #Down
            28   28  27 1 #Down
            29   28  29 1
            30   29  30 1
            31   30  31 1
            32   31  32 1
            33   32  33 1
            34   28  33 1
            35   30  34 1
            36   34  35 1 #Up
            37   34  36 1
            38   36  37 1
            39   33  38 1 #Down

» Japanese version   » Back

KEGG   DRUG: Streptomycin sulfate
Entry
D01350                      Drug                                   
Name
Streptomycin sulfate (JP18/USP);
Streptomycin sulfate (TN)
Product
  Generic
STREPTOMYCIN (XGen Pharmaceuticals DJB)
Formula
(C21H39N7O12)2. 3H2SO4
Exact mass
1456.4335
Mol weight
1457.3836
Structure
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
 DG01966  Antitubercular
Remark
Therapeutic category: 6161
ATC code: A07AA04 J01GA01
Chemical structure group: DG00082
Product (DG00082): D01350<JP/US>
Efficacy
Antibacterial (tuberculostatic), Antibiotic, Protein biosynthesis inhibitor
  Disease
Tuberculosis [DS:H00342]
Plague [DS:H00297]
Tularemia [DS:H00312]
Brucellosis [DS:H00325]
Donovanosis, Granuloma inguinale [DS:H01415]
Chancroid [DS:H00305]
Endocardial infection [DS:H00334]
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07A INTESTINAL ANTIINFECTIVES
    A07AA Antibiotics
     A07AA04 Streptomycin
      D01350  Streptomycin sulfate (JP18/USP) <JP/US>
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GA Streptomycins
     J01GA01 Streptomycin
      D01350  Streptomycin sulfate (JP18/USP) <JP/US>
USP drug classification [BR:br08302]
 Antibacterials
  Aminoglycosides
   Streptomycin
    D01350  Streptomycin sulfate (JP18/USP)
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   616  Acting mainly on acid-fast bacteria
    6161  Streptomycin antibiotics
     D01350  Streptomycin sulfate (JP18/USP)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00082  Streptomycin
    D01350  Streptomycin sulfate
  DG01966  Antitubercular
   DG00082  Streptomycin
    D01350  Streptomycin sulfate
Drug classes [BR:br08332]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   D01350  Streptomycin sulfate
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D01350  Streptomycin sulfate (JP18/USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01350  Streptomycin sulfate
  D01350  Streptomycin sulfate for injection
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00082  Streptomycin
  DG01966  Antitubercular
   DG00082  Streptomycin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00082  Streptomycin
Other DBs
CAS: 3810-74-0
PubChem: 7848413
ChEBI: 32158
LigandBox: D01350
NIKKAJI: J311.553D
LinkDB
KCF data

ATOM        95
            1   O1d O    16.9199  -15.1376
            2   S4a S    18.3197  -15.1376
            3   O1d O    18.3126  -16.5374
            4   O1d O    19.7196  -15.1376
            5   O1d O    18.3126  -13.7377
            6   C1y C     7.9748  -17.3139
            7   C1y C     8.3840  -16.0619
            8   C1z C     6.6623  -17.3139
            9   O2a O     9.6542  -18.4157
            10  O2a O     9.9192  -14.7014
            11  O2x O     7.3126  -15.2974
            12  C1y C     6.2652  -16.0619
            13  C4a C     5.3562  -18.0424
            14  O1a O     6.6684  -18.5720
            15  C1y C     8.5706  -20.4924
            16  C1y C     9.8890  -13.0759
            17  C1a C     5.0190  -15.6525
            18  O4a O     4.2303  -17.3741
            19  C1y C     8.5706  -21.8167
            20  O2x O     7.4208  -19.8364
            21  C1y C     8.7572  -12.4078
            22  C1y C    11.0388  -12.4078
            23  C1y C     7.4208  -22.4850
            24  C1y C     6.2891  -20.4924
            25  C1y C     8.7572  -11.0835
            26  N1b N     6.9273  -13.2264
            27  C1y C    11.0388  -11.0835
            28  O1a O    12.1705  -13.0580
            29  C1y C     6.2891  -21.8167
            30  O1a O     7.4208  -23.7973
            31  C1b C     5.1575  -19.8364
            32  C1y C     9.8890  -10.4272
            33  O1a O     7.8409  -10.3508
            34  C2c C     5.7955  -12.5703
            35  O1a O    12.1705  -10.4213
            36  O1a O     5.1513  -22.4670
            37  O1a O     4.0196  -20.4924
            38  N1b N     9.8830   -9.1149
            39  N1a N     4.6578  -13.2204
            40  N2a N     5.8015  -11.2581
            41  C2c C     8.7513   -8.4648
            42  N2a N     8.7452   -7.1585
            43  N1a N     7.6195   -9.1209
            44  N1b N     9.7777  -22.5113
            45  C1a C    10.9870  -21.8106
            46  O1d O    16.9199  -15.1376
            47  S4a S    18.3197  -15.1376
            48  O1d O    18.3126  -16.5374
            49  O1d O    19.7196  -15.1376
            50  O1d O    18.3126  -13.7377
            51  O1d O    16.9199  -15.1376
            52  S4a S    18.3197  -15.1376
            53  O1d O    18.3126  -16.5374
            54  O1d O    19.7196  -15.1376
            55  O1d O    18.3126  -13.7377
            56  C1y C     7.9748  -17.3139
            57  C1y C     8.3840  -16.0619
            58  O2a O     9.9192  -14.7014
            59  C1y C     9.8890  -13.0759
            60  C1y C     8.7572  -12.4078
            61  C1y C     8.7572  -11.0835
            62  C1y C     9.8890  -10.4272
            63  N1b N     9.8830   -9.1149
            64  C2c C     8.7513   -8.4648
            65  N2a N     8.7452   -7.1585
            66  N1a N     7.6195   -9.1209
            67  C1y C    11.0388  -11.0835
            68  C1y C    11.0388  -12.4078
            69  O1a O    12.1705  -13.0580
            70  O1a O    12.1705  -10.4213
            71  O1a O     7.8409  -10.3508
            72  N1b N     6.9273  -13.2264
            73  C2c C     5.7955  -12.5703
            74  N1a N     4.6578  -13.2204
            75  N2a N     5.8015  -11.2581
            76  O2x O     7.3126  -15.2974
            77  C1y C     6.2652  -16.0619
            78  C1z C     6.6623  -17.3139
            79  C4a C     5.3562  -18.0424
            80  O4a O     4.2303  -17.3741
            81  O1a O     6.6684  -18.5720
            82  C1a C     5.0190  -15.6525
            83  O2a O     9.6542  -18.4157
            84  C1y C     8.5706  -20.4924
            85  C1y C     8.5706  -21.8167
            86  C1y C     7.4208  -22.4850
            87  C1y C     6.2891  -21.8167
            88  O1a O     5.1513  -22.4670
            89  C1y C     6.2891  -20.4924
            90  O2x O     7.4208  -19.8364
            91  C1b C     5.1575  -19.8364
            92  O1a O     4.0196  -20.4924
            93  O1a O     7.4208  -23.7973
            94  N1b N     9.7777  -22.5113
            95  C1a C    10.9870  -21.8106
BOND        96
            1     1   2 1
            2     2   3 2
            3     2   4 1
            4     2   5 2
            5    46  47 1
            6    47  48 2
            7    47  49 1
            8    47  50 2
            9    51  52 1
            10   52  53 2
            11   52  54 1
            12   52  55 2
            13    6   7 1
            14    6   8 1
            15    6   9 1 #Down
            16    7  10 1 #Up
            17    7  11 1
            18    8  12 1
            19    8  13 1 #Up
            20    8  14 1
            21   15   9 1 #Up
            22   16  10 1 #Down
            23   12  17 1 #Down
            24   13  18 2
            25   15  19 1
            26   15  20 1
            27   16  21 1
            28   16  22 1
            29   19  23 1
            30   20  24 1
            31   21  25 1
            32   21  26 1 #Up
            33   22  27 1
            34   22  28 1 #Up
            35   23  29 1
            36   23  30 1 #Down
            37   24  31 1 #Down
            38   25  32 1
            39   25  33 1 #Down
            40   26  34 1
            41   27  35 1 #Down
            42   29  36 1 #Up
            43   31  37 1
            44   32  38 1 #Up
            45   34  39 1
            46   34  40 2
            47   38  41 1
            48   41  42 2
            49   41  43 1
            50   11  12 1
            51   24  29 1
            52   27  32 1
            53   19  44 1 #Up
            54   44  45 1
            55   56  57 1
            56   56  78 1
            57   56  83 1 #Down
            58   57  58 1 #Up
            59   57  76 1
            60   78  77 1
            61   78  79 1 #Up
            62   78  81 1
            63   84  83 1 #Up
            64   59  58 1 #Down
            65   77  82 1 #Down
            66   79  80 2
            67   84  85 1
            68   84  90 1
            69   59  60 1
            70   59  68 1
            71   85  86 1
            72   90  89 1
            73   60  61 1
            74   60  72 1 #Up
            75   68  67 1
            76   68  69 1 #Up
            77   86  87 1
            78   86  93 1 #Down
            79   89  91 1 #Down
            80   61  62 1
            81   61  71 1 #Down
            82   72  73 1
            83   67  70 1 #Down
            84   87  88 1 #Up
            85   91  92 1
            86   62  63 1 #Up
            87   73  74 1
            88   73  75 2
            89   63  64 1
            90   64  65 2
            91   64  66 1
            92   76  77 1
            93   89  87 1
            94   67  62 1
            95   85  94 1 #Up
            96   94  95 1
BRACKET     1    15.5400  -17.5000   15.5400  -12.8800
            1    21.0000  -12.8800   21.0000  -17.5000
            1  3
 ORIGINAL  1    1   2   3   4   5
 REPEAT    1   46  47  48  49  50  51  52  53  54  55
            2     2.2400  -24.4300    2.2400   -6.3000
            2    13.7900   -6.3000   13.7900  -24.4300
            2  2
 ORIGINAL  2    6   7  10  16  21  25  32  38  41  42  43  27  22  28  35  33
            2   26  34  39  40  11  12   8  13  18  14  17   9  15  19  23  29
            2   36  24  20  31  37  30  44  45
 REPEAT    2   56  57  58  59  60  61  62  63  64  65  66  67  68  69  70  71
            2   72  73  74  75  76  77  78  79  80  81  82  83  84  85  86  87
            2   88  89  90  91  92  93  94  95

» Japanese version   » Back

KEGG   DRUG: Arbekacin sulfate
Entry
D01523                      Drug                                   
Name
Arbekacin sulfate (JP18);
Habekacin (TN)
Formula
C22H44N6O10. H2SO4
Exact mass
650.2793
Mol weight
650.6974
Structure
Simcomp
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
Therapeutic category: 6119
ATC code: J01GB12
Chemical structure group: DG00614
Product (DG00614): D01523<JP>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB12 Arbekacin
      D01523  Arbekacin sulfate (JP18) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   611  Acting mainly on gram-positive bacteria
    6119  Others
     D01523  Arbekacin sulfate (JP18)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00614  Arbekacin
    D01523  Arbekacin sulfate
Drug classes [BR:br08332]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   D01523  Arbekacin sulfate
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D01523  Arbekacin sulfate (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01523  Arbekacin sulfate
  D01523  Arbekacin sulfate injection
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00614  Arbekacin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00614  Arbekacin
Other DBs
CAS: 104931-87-5
PubChem: 7848586
ChEBI: 31233
LigandBox: D01523
LinkDB
KCF data

ATOM        43
            1   O1d O    32.3166  -17.1850
            2   S4a S    33.7115  -17.1850
            3   O1d O    33.7745  -18.5798
            4   O1d O    35.1063  -17.1850
            5   O1d O    33.7745  -15.7902
            6   O2a O    24.0155  -13.9248
            7   C1y C    25.2255  -13.2121
            8   O2x O    26.4372  -13.9099
            9   C1y C    27.6402  -13.1972
            10  C1x C    27.6305  -11.7953
            11  C1x C    26.4178  -11.1063
            12  C1y C    25.2078  -11.8120
            13  C1b C    28.8600  -13.8931
            14  N1a N    28.8696  -15.2949
            15  N1a N    23.9859  -11.1266
            16  C1y C    24.0348  -15.3265
            17  C1y C    25.2588  -16.0079
            18  C1x C    25.2759  -17.4121
            19  C1y C    24.0723  -18.1290
            20  C1y C    22.8483  -17.4405
            21  C1y C    22.8276  -16.0425
            22  N1a N    26.4648  -15.2951
            23  N1b N    24.0899  -19.5307
            24  O1a O    21.6027  -15.3627
            25  O2a O    21.6431  -18.1620
            26  C1y C    20.4333  -18.8666
            27  C1y C    20.4422  -20.2677
            28  C1y C    19.2325  -20.9793
            29  C1y C    18.0208  -20.2829
            30  C1y C    18.0120  -18.8820
            31  O2x O    19.2147  -18.1773
            32  O1a O    21.6616  -20.9644
            33  O1a O    16.8102  -20.9950
            34  C1b C    16.7925  -18.1922
            35  N1a N    19.2413  -22.3812
            36  O1a O    15.5819  -18.8972
            37  C5a C    25.2962  -20.2265
            38  C1c C    26.5079  -19.5290
            39  C1b C    27.7125  -20.2265
            40  C1b C    28.9242  -19.5290
            41  N1a N    30.1358  -20.2265
            42  O5a O    25.2957  -21.6284
            43  O1a O    26.5079  -18.1271
BOND        44
            1     2   3 2
            2     2   4 1
            3     1   2 1
            4     2   5 2
            5     9  10 1
            6    17  22 1 #Up
            7    10  11 1
            8    19  23 1 #Up
            9    11  12 1
            10   21  24 1 #Up
            11   12   7 1
            12   20  25 1 #Down
            13   16   6 1 #Down
            14   26  25 1 #Down
            15    9  13 1 #Up
            16    7   6 1 #Down
            17   13  14 1
            18   12  15 1 #Down
            19   26  27 1
            20   27  28 1
            21   28  29 1
            22   29  30 1
            23   30  31 1
            24   31  26 1
            25   27  32 1 #Down
            26   29  33 1 #Down
            27   30  34 1 #Up
            28   28  35 1 #Up
            29    7   8 1
            30   34  36 1
            31    8   9 1
            32   23  37 1
            33   16  17 1
            34   37  38 1
            35   17  18 1
            36   38  39 1
            37   18  19 1
            38   39  40 1
            39   19  20 1
            40   40  41 1
            41   20  21 1
            42   37  42 2
            43   21  16 1
            44   38  43 1 #Up

» Japanese version   » Back

KEGG   DRUG: Neomycin sulfate
Entry
D01618                      Drug                                   
Name
Neomycin sulfate (USP);
Fradiomycin sulfate (JP18);
Mycifradin (TN);
Neo-fradin (TN);
Sofratulle (TN)
Product
  Generic
NEOMYCIN SULFATE (Chartwell RX), NEOMYCIN SULFATE (Solaris Pharma Corporation), NEOMYCIN SULFATE (Teva Pharmaceuticals USA), NEOMYCIN SULFATE (XGen Pharmaceuticals DJB)
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
Therapeutic category: 2634 2760
ATC code: A01AB08 A07AA01 B05CA09 D06AX04 J01GB05 R02AB01 S01AA03 S02AA07 S03AA01
Chemical structure group: DG00003
Product (DG00003): D01618<JP/US>
Product (mixture): D02139<US> D02531<US> D04246<JP> D04250<JP> D04699<JP> D04753<JP> D04755<JP> D04795<JP/US> D04796<JP> D04806<JP> D11096<US> D11177<US> D11855<US> D12134<US> D12135<US>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AB Antiinfectives and antiseptics for local oral treatment
     A01AB08 Neomycin
      D01618  Neomycin sulfate (USP) <JP/US>
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07A INTESTINAL ANTIINFECTIVES
    A07AA Antibiotics
     A07AA01 Neomycin
      D01618  Neomycin sulfate (USP) <JP/US>
 B BLOOD AND BLOOD FORMING ORGANS
  B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
   B05C IRRIGATING SOLUTIONS
    B05CA Antiinfectives
     B05CA09 Neomycin
      D01618  Neomycin sulfate (USP) <JP/US>
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06A ANTIBIOTICS FOR TOPICAL USE
    D06AX Other antibiotics for topical use
     D06AX04 Neomycin
      D01618  Neomycin sulfate (USP) <JP/US>
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB05 Neomycin
      D01618  Neomycin sulfate (USP) <JP/US>
 R RESPIRATORY SYSTEM
  R02 THROAT PREPARATIONS
   R02A THROAT PREPARATIONS
    R02AB Antibiotics
     R02AB01 Neomycin
      D01618  Neomycin sulfate (USP) <JP/US>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA03 Neomycin
      D01618  Neomycin sulfate (USP) <JP/US>
  S02 OTOLOGICALS
   S02A ANTIINFECTIVES
    S02AA Antiinfectives
     S02AA07 Neomycin
      D01618  Neomycin sulfate (USP) <JP/US>
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03A ANTIINFECTIVES
    S03AA Antiinfectives
     S03AA01 Neomycin
      D01618  Neomycin sulfate (USP) <JP/US>
USP drug classification [BR:br08302]
 Antibacterials
  Aminoglycosides
   Neomycin
    D01618  Neomycin sulfate (USP)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  26  Epidermides
   263  Suppurative dermatosis agents
    2634  Antibiotics for external use
     D01618  Neomycin sulfate (USP); Fradiomycin sulfate (JP18)
  27  Dental preparations
   276  Antibiotics
    2760  Antibiotics
     D01618  Neomycin sulfate (USP); Fradiomycin sulfate (JP18)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Fradiomycin
    D01618  Neomycin sulfate (USP)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00003  Neomycin
    D01618  Neomycin sulfate
Drug classes [BR:br08332]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   D01618  Neomycin sulfate
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D01618  Neomycin sulfate (USP) <JP/US>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01618  Fradiomycin sulfate
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00003  Neomycin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00003  Neomycin
Other DBs
CAS: 1405-10-3
PubChem: 7848681
ChEBI: 31635
NIKKAJI: J300.828B
LinkDB

» Japanese version   » Back

KEGG   DRUG: Dibekacin sulfate
Entry
D01753                      Drug                                   
Name
Dibekacin sulfate (JP18);
Panimycin (TN)
Formula
C18H37N5O8. xH2SO4
Structure
Simcomp
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
Therapeutic category: 1317 6134
ATC code: J01GB09 S01AA29
Chemical structure group: DG00611
Product (DG00611): D01753<JP>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB09 Dibekacin
      D01753  Dibekacin sulfate (JP18) <JP>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA29 Dibekacin
      D01753  Dibekacin sulfate (JP18) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 1  Agents affecting nervous system and sensory organs
  13  Agents affecting sensory organs
   131  Ophthalmic agents
    1317  Ophthalmic antibiotics
     D01753  Dibekacin sulfate (JP18)
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6134  Amino sugars
     D01753  Dibekacin sulfate (JP18)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00611  Dibekacin
    D01753  Dibekacin sulfate
Drug classes [BR:br08332]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   D01753  Dibekacin sulfate
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D01753  Dibekacin sulfate (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01753  Dibekacin sulfate
  D01753  Dibekacin sulfate ophthalmic solution
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00611  Dibekacin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00611  Dibekacin
Other DBs
CAS: 58580-55-5
PubChem: 7848816
ChEBI: 31475
LigandBox: D01753
NIKKAJI: J300.240C
LinkDB
KCF data

ATOM        36
            1   O1d O    29.9635  -18.6462
            2   S4a S    31.3576  -18.6462
            3   O1d O    31.3506  -20.0402
            4   O1d O    32.7516  -18.6462
            5   O1d O    31.3506  -17.2522
            6   C1y C    19.7925  -17.1321
            7   C1y C    19.7925  -18.5332
            8   C1y C    21.0098  -19.2370
            9   C1y C    22.2198  -18.5332
            10  C1y C    22.2198  -17.1321
            11  O2x O    21.0098  -16.4351
            12  N1a N    21.0115  -20.6382
            13  O1a O    18.5786  -19.2377
            14  O1a O    23.4347  -19.2362
            15  O2a O    23.4347  -16.4359
            16  C1y C    24.6364  -15.7241
            17  C1y C    25.8547  -16.4192
            18  C1x C    26.9935  -15.7073
            19  C1y C    27.0539  -14.3071
            20  C1y C    25.8354  -13.6189
            21  C1y C    24.6268  -14.3238
            22  N1a N    25.8643  -17.8203
            23  N1a N    28.2631  -13.6018
            24  O2a O    25.8258  -12.2179
            25  O1a O    23.4146  -13.6353
            26  C1y C    27.0353  -11.5054
            27  O2x O    28.2460  -12.2029
            28  C1y C    29.4554  -11.4905
            29  C1x C    29.4457  -10.0894
            30  C1x C    28.2266   -9.4008
            31  C1y C    27.0174  -10.1061
            32  C1b C    30.6745  -12.1862
            33  N1a N    30.6841  -13.5871
            34  N1a N    25.7962   -9.4211
            35  C1b C    18.5786  -16.4344
            36  O1a O    17.3639  -17.1309
BOND        37
            1     2   5 2
            2     1   2 1
            3     2   3 2
            4     2   4 1
            5     6   7 1
            6     7   8 1
            7     8   9 1
            8    16  17 1
            9    17  18 1
            10   18  19 1
            11   19  20 1
            12   20  21 1
            13   21  16 1
            14    9  10 1
            15   17  22 1 #Up
            16   10  11 1
            17   19  23 1 #Up
            18   11   6 1
            19   20  24 1 #Down
            20   21  25 1 #Up
            21    8  12 1 #Up
            22   26  24 1 #Down
            23    7  13 1 #Down
            24    9  14 1 #Down
            25   26  27 1
            26   27  28 1
            27   28  29 1
            28   29  30 1
            29   30  31 1
            30   31  26 1
            31   10  15 1 #Down
            32   28  32 1 #Up
            33   32  33 1
            34   16  15 1 #Down
            35   31  34 1 #Down
            36    6  35 1 #Up
            37   35  36 1
BRACKET     1    28.4900  -20.9300   28.4900  -16.3100
            1    33.9500  -16.3100   33.9500  -20.9300
            1  x
 ORIGINAL  1    1   2   3   4   5
 REPEAT    1

» Japanese version   » Back

KEGG   DRUG: Isepamicin sulfate
Entry
D01826                      Drug                                   
Name
Isepamicin sulfate (JP18);
Isepacin (TN)
Formula
C22H43N5O12. xH2SO4
Structure
Simcomp
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
Therapeutic category: 6123
ATC code: J01GB11
Chemical structure group: DG00613
Product (DG00613): D01826<JP>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB11 Isepamicin
      D01826  Isepamicin sulfate (JP18) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   612  Acting mainly on gram-negative bacteria
    6123  Amino sugars
     D01826  Isepamicin sulfate (JP18)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00613  Isepamicin
    D01826  Isepamicin sulfate
Drug classes [BR:br08332]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   D01826  Isepamicin sulfate
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D01826  Isepamicin sulfate (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01826  Isepamicin sulfate
  D01826  Isepamicin sulfate injection
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00613  Isepamicin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00613  Isepamicin
Other DBs
CAS: 67814-76-0
PubChem: 7848888
ChEBI: 31722
LigandBox: D01826
NIKKAJI: J245.543I
LinkDB
KCF data

ATOM        44
            1   S4a S    39.5251  -14.9690
            2   O1d O    40.9206  -14.9690
            3   O1d O    38.1296  -14.9621
            4   O1d O    39.5180  -16.3644
            5   O1d O    39.5180  -13.5735
            6   C1y C    33.2500  -13.0900
            7   C1y C    33.2500  -11.6900
            8   C1y C    32.0600  -10.9900
            9   C1y C    30.8000  -11.6900
            10  C1y C    30.8000  -13.0900
            11  O2x O    32.0600  -13.7900
            12  O2a O    29.6100  -13.7900
            13  C1y C    29.6100  -15.1900
            14  C1y C    28.3500  -15.8900
            15  C1y C    28.3500  -17.2900
            16  C1y C    29.6100  -17.9900
            17  C1x C    30.8000  -17.2900
            18  C1y C    30.8000  -15.8900
            19  O2a O    27.0900  -17.9900
            20  C1b C    34.4400  -13.7900
            21  O1a O    29.6100  -10.9900
            22  N1a N    32.0600  -15.1900
            23  N1b N    29.6100  -19.3900
            24  O1a O    27.0900  -15.1900
            25  N1a N    34.4400  -15.1900
            26  C1y C    25.8300  -17.4300
            27  O2x O    25.8300  -16.0300
            28  C1x C    24.5000  -15.3300
            29  C1z C    23.3800  -16.1000
            30  C1y C    23.3800  -17.5000
            31  C1y C    24.6400  -18.1300
            32  O1a O    24.7100  -19.5300
            33  O1a O    22.2600  -15.4000
            34  N1b N    22.1900  -18.2000
            35  C1a C    21.0000  -17.6400
            36  O1a O    34.4400  -10.9900
            37  O1a O    32.0600   -9.5900
            38  C5a C    30.8000  -20.0900
            39  C1c C    31.9900  -19.3900
            40  C1b C    33.2500  -20.0900
            41  N1a N    34.4400  -19.3900
            42  O5a O    30.8000  -21.4900
            43  O1a O    31.9900  -17.9900
            44  C1a C    23.3800  -14.4900
BOND        45
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     1   5 2
            5    13  14 1
            6    14  15 1
            7    15  16 1
            8    26  27 1
            9    27  28 1
            10   28  29 1
            11   29  30 1
            12   30  31 1
            13   31  26 1
            14   16  17 1
            15   31  32 1 #Down
            16   17  18 1
            17   18  13 1
            18   29  33 1 #Up
            19   11   6 1
            20   30  34 1 #Up
            21   15  19 1 #Down
            22   34  35 1
            23    6  20 1 #Up
            24   10  12 1 #Down
            25    9  21 1 #Down
            26   18  22 1 #Up
            27   13  12 1 #Down
            28    7  36 1 #Down
            29   16  23 1 #Up
            30    8  37 1 #Up
            31    6   7 1
            32   14  24 1 #Up
            33    7   8 1
            34   20  25 1
            35    8   9 1
            36   26  19 1 #Down
            37    9  10 1
            38   10  11 1
            39   23  38 1
            40   38  39 1
            41   39  40 1
            42   40  41 1
            43   38  42 2
            44   39  43 1 #Up
            45   29  44 1 #Down
BRACKET     1    36.6800  -17.3600   36.6800  -12.6000
            1    42.1400  -12.6000   42.1400  -17.3600
            1  x
 ORIGINAL  1    1   2   3   4   5
 REPEAT    1

» Japanese version   » Back

KEGG   DRUG: Bekanamycin sulfate
Entry
D01868                      Drug                                   
Name
Bekanamycin sulfate (JP18);
AKM;
Kanendomycin (TN)
Formula
C18H37N5O10. xH2SO4
Structure
Simcomp
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
ATC code: J01GB13
Chemical structure group: DG00615
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB13 Bekanamycin
      D01868  Bekanamycin sulfate (JP18)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00615  Bekanamycin
    D01868  Bekanamycin sulfate
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D01868  Bekanamycin sulfate (JP18)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D01868  Bekanamycin sulfate
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00615  Bekanamycin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00615  Bekanamycin
Other DBs
PubChem: 7848930
ChEBI: 31255
LigandBox: D01868
LinkDB
KCF data

ATOM        38
            1   C1y C    29.3765  -15.4314
            2   C1y C    29.3765  -14.0313
            3   C1y C    28.1611  -13.3312
            4   C1y C    26.9528  -14.0313
            5   C1y C    26.9528  -15.4314
            6   O2x O    28.1611  -16.1314
            7   O2a O    25.7397  -16.1306
            8   C1y C    25.7387  -17.5307
            9   C1y C    24.5247  -18.2262
            10  C1y C    24.5237  -19.6262
            11  C1y C    25.7356  -20.3271
            12  C1x C    26.9487  -19.6281
            13  C1y C    26.9497  -18.2280
            14  O2a O    23.3106  -20.3254
            15  C1b C    30.5888  -16.1321
            16  N1a N    25.7397  -13.3321
            17  N1a N    28.1621  -17.5276
            18  N1a N    25.7346  -21.7272
            19  O1a O    23.3135  -17.5237
            20  N1a N    30.5879  -17.5322
            21  C1y C    22.0932  -21.0177
            22  O2x O    20.8850  -20.3095
            23  C1y C    19.6677  -21.0017
            24  C1y C    19.6583  -22.4022
            25  C1y C    20.8667  -23.1102
            26  C1y C    22.1540  -22.4181
            27  O1a O    30.5888  -13.3306
            28  O1a O    28.1594  -11.9311
            29  C1b C    18.4599  -20.2937
            30  O1a O    17.2427  -20.9856
            31  O1a O    18.4414  -23.0942
            32  N1a N    20.8575  -24.5101
            33  O1a O    23.3620  -23.1262
            34  S4a S    31.1922  -23.5895
            35  O1d O    32.5922  -23.5895
            36  O1d O    29.7922  -23.5825
            37  O1d O    31.1851  -22.1895
            38  O1d O    31.1851  -24.9894
BOND        39
            1    26  21 1
            2    11  12 1
            3    12  13 1
            4    13   8 1
            5     6   1 1
            6    10  14 1 #Down
            7     1  15 1 #Up
            8     5   7 1 #Down
            9     4  16 1 #Down
            10   13  17 1 #Up
            11    8   7 1 #Down
            12    2  27 1 #Down
            13   11  18 1 #Up
            14    3  28 1 #Up
            15    1   2 1
            16    9  19 1 #Up
            17    2   3 1
            18   15  20 1
            19    3   4 1
            20   23  29 1 #Up
            21   29  30 1
            22   21  14 1 #Down
            23   24  31 1 #Down
            24    4   5 1
            25   25  32 1 #Up
            26    5   6 1
            27   26  33 1 #Down
            28    8   9 1
            29    9  10 1
            30   10  11 1
            31   21  22 1
            32   22  23 1
            33   23  24 1
            34   24  25 1
            35   25  26 1
            36   34  35 1
            37   34  36 1
            38   34  37 2
            39   34  38 2
BRACKET     1    28.3500  -25.6200   28.3500  -21.2800
            1    33.9500  -21.2800   33.9500  -25.6200
            1  x
 ORIGINAL  1   34  35  36  37  38
 REPEAT    1

» Japanese version   » Back

KEGG   DRUG: Sisomicin sulfate
Entry
D02181                      Drug                                   
Name
Sisomicin sulfate (JAN/USP);
Siseptin (TN)
Formula
(C19H37N5O7)2. 5H2SO4
Exact mass
1384.3755
Mol weight
1385.4452
Structure
Simcomp
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
ATC code: J01GB08
Chemical structure group: DG00610
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB08 Sisomicin
      D02181  Sisomicin sulfate (JAN/USP)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00610  Sisomicin
    D02181  Sisomicin sulfate
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D02181  Sisomicin sulfate (JAN/USP)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00610  Sisomicin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00610  Sisomicin
Other DBs
CAS: 53179-09-2
PubChem: 7849241
LigandBox: D02181
NIKKAJI: J365.084G
LinkDB
KCF data

ATOM        87
            1   C1y C    28.1673  -17.0155
            2   C1y C    29.3663  -17.7176
            3   C1y C    28.1673  -15.6094
            4   O2a O    26.9496  -17.6942
            5   C1x C    30.5770  -17.0272
            6   N1a N    29.3604  -19.1295
            7   C1y C    29.3780  -14.9193
            8   O1a O    26.9613  -14.9076
            9   C1y C    25.7318  -18.3959
            10  C1y C    30.5711  -15.6341
            11  O2a O    29.4085  -13.5203
            12  C1y C    25.7445  -19.7950
            13  O2x O    24.5210  -17.7000
            14  N1a N    31.9281  -15.2645
            15  C1y C    30.6320  -12.8358
            16  C1y C    24.5326  -20.4980
            17  O1a O    26.9554  -20.4794
            18  C1x C    23.3033  -18.4147
            19  O2x O    31.8439  -13.5203
            20  C1y C    30.6320  -11.4310
            21  C1z C    23.3091  -19.8007
            22  N1b N    24.5515  -21.8971
            23  C2y C    33.0487  -12.8358
            24  C1x C    31.8439  -10.7279
            25  N1a N    29.4202  -10.7279
            26  O1a O    21.8795  -20.0255
            27  C1a C    23.5513  -22.8844
            28  C2x C    33.0487  -11.4310
            29  C1b C    34.2723  -13.5203
            30  N1a N    34.2782  -14.9193
            31  C1a C    23.0554  -21.1867
            32  S4a S    40.7256  -16.5812
            33  O1d O    39.3266  -16.5753
            34  O1d O    42.1247  -16.5812
            35  O1d O    40.7197  -15.1879
            36  O1d O    40.7197  -17.9803
            37  C1y C    28.1673  -17.0155
            38  C1y C    29.3663  -17.7176
            39  C1x C    30.5770  -17.0272
            40  C1y C    30.5711  -15.6341
            41  N1a N    31.9281  -15.2645
            42  C1y C    29.3780  -14.9193
            43  C1y C    28.1673  -15.6094
            44  O1a O    26.9613  -14.9076
            45  O2a O    29.4085  -13.5203
            46  C1y C    30.6320  -12.8358
            47  O2x O    31.8439  -13.5203
            48  C2y C    33.0487  -12.8358
            49  C2x C    33.0487  -11.4310
            50  C1x C    31.8439  -10.7279
            51  C1y C    30.6320  -11.4310
            52  N1a N    29.4202  -10.7279
            53  C1b C    34.2723  -13.5203
            54  N1a N    34.2782  -14.9193
            55  N1a N    29.3604  -19.1295
            56  O2a O    26.9496  -17.6942
            57  C1y C    25.7318  -18.3959
            58  C1y C    25.7445  -19.7950
            59  C1y C    24.5326  -20.4980
            60  C1z C    23.3091  -19.8007
            61  C1x C    23.3033  -18.4147
            62  O2x O    24.5210  -17.7000
            63  O1a O    21.8795  -20.0255
            64  C1a C    23.0554  -21.1867
            65  N1b N    24.5515  -21.8971
            66  C1a C    23.5513  -22.8844
            67  O1a O    26.9554  -20.4794
            68  S4a S    40.7256  -16.5812
            69  O1d O    39.3266  -16.5753
            70  O1d O    42.1247  -16.5812
            71  O1d O    40.7197  -15.1879
            72  O1d O    40.7197  -17.9803
            73  S4a S    40.7256  -16.5812
            74  O1d O    39.3266  -16.5753
            75  O1d O    42.1247  -16.5812
            76  O1d O    40.7197  -15.1879
            77  O1d O    40.7197  -17.9803
            78  S4a S    40.7256  -16.5812
            79  O1d O    39.3266  -16.5753
            80  O1d O    42.1247  -16.5812
            81  O1d O    40.7197  -15.1879
            82  O1d O    40.7197  -17.9803
            83  S4a S    40.7256  -16.5812
            84  O1d O    39.3266  -16.5753
            85  O1d O    42.1247  -16.5812
            86  O1d O    40.7197  -15.1879
            87  O1d O    40.7197  -17.9803
BOND        86
            1    18  21 1
            2    24  28 1
            3     1   2 1
            4     1   3 1
            5     1   4 1 #Down
            6     2   5 1
            7     2   6 1 #Up
            8     3   7 1
            9     3   8 1 #Up
            10    9   4 1 #Down
            11    5  10 1
            12    7  11 1 #Down
            13    9  12 1
            14    9  13 1
            15   10  14 1 #Up
            16   15  11 1 #Down
            17   12  16 1
            18   12  17 1 #Down
            19   13  18 1
            20   15  19 1
            21   15  20 1
            22   16  21 1
            23   16  22 1 #Up
            24   19  23 1
            25   20  24 1
            26   20  25 1 #Down
            27   21  26 1 #Up
            28   22  27 1
            29   23  28 2
            30   23  29 1
            31   29  30 1
            32    7  10 1
            33   21  31 1 #Down
            34   61  60 1
            35   50  49 1
            36   37  38 1
            37   37  43 1
            38   37  56 1 #Down
            39   38  39 1
            40   38  55 1 #Up
            41   43  42 1
            42   43  44 1 #Up
            43   57  56 1 #Down
            44   39  40 1
            45   42  45 1 #Down
            46   57  58 1
            47   57  62 1
            48   40  41 1 #Up
            49   46  45 1 #Down
            50   58  59 1
            51   58  67 1 #Down
            52   62  61 1
            53   46  47 1
            54   46  51 1
            55   59  60 1
            56   59  65 1 #Up
            57   47  48 1
            58   51  50 1
            59   51  52 1 #Down
            60   60  63 1 #Up
            61   65  66 1
            62   48  49 2
            63   48  53 1
            64   53  54 1
            65   42  40 1
            66   60  64 1 #Down
            67   32  33 1
            68   32  34 1
            69   32  35 2
            70   32  36 2
            71   68  69 1
            72   68  70 1
            73   68  71 2
            74   68  72 2
            75   73  74 1
            76   73  75 1
            77   73  76 2
            78   73  77 2
            79   78  79 1
            80   78  80 1
            81   78  81 2
            82   78  82 2
            83   83  84 1
            84   83  85 1
            85   83  86 2
            86   83  87 2
BRACKET     1    20.4400  -24.2900   20.4400  -10.0800
            1    35.7700  -10.0800   35.7700  -24.2900
            1  2
 ORIGINAL  1    1   2   5  10  14   7   3   8  11  15  19  23  28  24  20  25
            1   29  30   6   4   9  12  16  21  18  13  26  31  22  27  17
 REPEAT    1   37  38  39  40  41  42  43  44  45  46  47  48  49  50  51  52
            1   53  54  55  56  57  58  59  60  61  62  63  64  65  66  67
            2    37.8700  -18.9000   37.8700  -14.2800
            2    43.4000  -14.2800   43.4000  -18.9000
            2  5
 ORIGINAL  2   32  33  34  35  36
 REPEAT    2   68  69  70  71  72  73  74  75  76  77  78  79  80  81  82  83
            2   84  85  86  87

» Japanese version   » Back

KEGG   DRUG: Ribostamycin sulfate
Entry
D02209                      Drug                                   
Name
Ribostamycin sulfate (JP18);
Vistamycin (TN)
Formula
C17H34N4O10. xH2SO4
Structure
Simcomp
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
ATC code: J01GB10
Chemical structure group: DG00612
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB10 Ribostamycin
      D02209  Ribostamycin sulfate (JP18)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00612  Ribostamycin
    D02209  Ribostamycin sulfate
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D02209  Ribostamycin sulfate (JP18)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02209  Ribostamycin sulfate
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00612  Ribostamycin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00612  Ribostamycin
Other DBs
CAS: 53797-35-6
PubChem: 7849269
ChEBI: 10003
LigandBox: D02209
NIKKAJI: J281.034D
LinkDB
KCF data

ATOM        36
            1   C1y C     9.8053   -8.6133
            2   C1y C     9.8053  -10.0035
            3   C1y C    11.0120  -10.6984
            4   C1x C    12.2116  -10.0035
            5   C1y C    12.2116   -8.6133
            6   C1y C    11.0120   -7.9183
            7   O2a O     8.3238   -7.9176
            8   C1y C     6.2906   -9.6666
            9   C1y C     6.7232   -8.3453
            10  O2x O     5.5955   -7.5252
            11  C1y C     4.4680   -8.3453
            12  C1y C     4.9005   -9.6666
            13  C1b C     3.1453   -7.9176
            14  O1a O     2.1137   -8.8490
            15  O1a O     7.1062  -10.7921
            16  O1a O     4.0847  -10.7920
            17  O1a O     8.8799  -10.7684
            18  N1a N    11.0137  -12.0884
            19  N1a N    13.4160   -7.9191
            20  O2a O    11.0137   -6.5282
            21  C1y C    12.2184   -5.8347
            22  O2x O    13.4194   -6.5316
            23  C1y C    14.6240   -5.8381
            24  C1y C    14.6257   -4.4481
            25  C1y C    13.4229   -3.7516
            26  C1y C    12.2183   -4.4451
            27  C1b C    15.8269   -6.5347
            28  N1a N    15.8252   -7.9247
            29  O1a O    15.8304   -3.7547
            30  O1a O    13.4246   -2.3616
            31  N1a N    11.0147   -3.7494
            32  S4a S    21.1120   -7.7400
            33  O1d O    21.1120   -6.3400
            34  O1d O    21.1120   -9.1400
            35  O1d O    19.7119   -7.7400
            36  O1d O    22.5119   -7.7400
BOND        37
            1     2  17 1 #Down
            2     1   2 1
            3     3  18 1 #Up
            4     2   3 1
            5     5  19 1 #Up
            6     3   4 1
            7     6  20 1 #Down
            8     4   5 1
            9    21  20 1 #Down
            10    8   9 1
            11    9  10 1
            12   10  11 1
            13   11  12 1
            14   12   8 1
            15   21  22 1
            16   22  23 1
            17   23  24 1
            18   24  25 1
            19   25  26 1
            20   26  21 1
            21    5   6 1
            22   23  27 1 #Up
            23   11  13 1 #Up
            24   27  28 1
            25    6   1 1
            26   24  29 1 #Down
            27   13  14 1
            28   25  30 1 #Up
            29    9   7 1 #Up
            30   26  31 1 #Down
            31    8  15 1 #Down
            32    1   7 1 #Up
            33   12  16 1 #Down
            34   32  33 2
            35   32  34 2
            36   32  35 1
            37   32  36 1
BRACKET     1    18.4800   -9.8700   18.4800   -5.7400
            1    23.8000   -5.7400   23.8000   -9.8700
            1  x
 ORIGINAL  1   32  33  34  35  36
 REPEAT    1

» Japanese version   » Back

KEGG   DRUG: Tobramycin sulfate
Entry
D02542                      Drug                                   
Name
Tobramycin sulfate (USP);
Nebcin (TN)
Product
TOBRAMYCIN (Fresenius Kabi USA), TOBRAMYCIN (Fresenius Kabi USA)
  Generic
TOBRAMYCIN (Baxter Healthcare Corporation), TOBRAMYCIN (Eugia US LLC), TOBRAMYCIN (Fosun Pharma USA), TOBRAMYCIN (Fresenius Kabi USA), TOBRAMYCIN (Fresenius Kabi USA), TOBRAMYCIN (Fresenius Kabi USA), TOBRAMYCIN (Gland Pharma Limited), TOBRAMYCIN (Gland Pharma Limited), TOBRAMYCIN (Gland Pharma Limited), TOBRAMYCIN (Hospira), TOBRAMYCIN (Mylan Institutional LLC), TOBRAMYCIN (Northstar Rx LLC), TOBRAMYCIN (XGen Pharmaceuticals DJB), TOBRAMYCIN (Xiromed LLC)
Formula
(C18H37N5O9)2. 5H2SO4
Exact mass
1424.3552
Mol weight
1425.4214
Structure
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
ATC code: J01GB01 S01AA12
Chemical structure group: DG00608
Product (DG00608): D00063<JP/US> D02542<US>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
50S ribosomal subunit
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB01 Tobramycin
      D02542  Tobramycin sulfate (USP) <US>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA12 Tobramycin
      D02542  Tobramycin sulfate (USP) <US>
USP drug classification [BR:br08302]
 Antibacterials
  Aminoglycosides
   Tobramycin
    D02542  Tobramycin sulfate (USP)
 Ophthalmic Agents
  Ophthalmic Anti-Infectives
   Antibacterials, Ophthalmic
    Tobramycin
     D02542  Tobramycin sulfate (USP)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00608  Tobramycin
    D02542  Tobramycin sulfate
Drug classes [BR:br08332]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   D02542  Tobramycin sulfate
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D02542  Tobramycin sulfate (USP) <US>
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00608  Tobramycin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00608  Tobramycin
Other DBs
CAS: 79645-27-5
PubChem: 17396713
LigandBox: D02542
LinkDB
KCF data

ATOM        89
            1   C1y C    16.6047  -20.3920
            2   C1y C    16.6047  -21.7937
            3   C1y C    17.7961  -22.4945
            4   C1y C    19.0576  -21.7937
            5   C1y C    19.0576  -20.3920
            6   O2x O    17.7961  -19.6912
            7   C1b C    15.4133  -19.6912
            8   O1a O    14.2218  -20.3920
            9   O1a O    15.4133  -22.4945
            10  N1a N    17.7961  -23.8962
            11  O1a O    20.2490  -22.4945
            12  O2a O    20.2490  -19.6912
            13  C1y C    21.4404  -18.9904
            14  C1y C    22.7019  -19.6912
            15  C1x C    23.8933  -18.9904
            16  C1y C    23.8933  -17.5887
            17  C1y C    22.6318  -16.8879
            18  C1y C    21.4404  -17.5887
            19  N1a N    22.7019  -21.0929
            20  N1a N    25.0146  -16.8879
            21  O1a O    20.2490  -16.8879
            22  O2a O    22.6318  -15.4862
            23  C1y C    23.8232  -14.7854
            24  O2x O    25.0847  -15.4862
            25  C1y C    26.2761  -14.7854
            26  C1y C    26.2761  -13.3838
            27  C1x C    25.0146  -12.6829
            28  C1y C    23.8232  -13.3838
            29  C1b C    27.5376  -15.4862
            30  N1a N    27.5376  -16.8879
            31  O1a O    27.4675  -12.6128
            32  N1a N    22.6318  -12.6829
            33  S4a S    33.9151  -18.7101
            34  O1d O    33.9151  -20.1117
            35  O1d O    33.9151  -17.3084
            36  O1d O    35.3168  -18.7101
            37  O1d O    32.5135  -18.7101
            38  C1y C    16.6047  -20.3920
            39  C1y C    16.6047  -21.7937
            40  C1y C    17.7961  -22.4945
            41  C1y C    19.0576  -21.7937
            42  C1y C    19.0576  -20.3920
            43  O2x O    17.7961  -19.6912
            44  O2a O    20.2490  -19.6912
            45  C1y C    21.4404  -18.9904
            46  C1y C    22.7019  -19.6912
            47  C1x C    23.8933  -18.9904
            48  C1y C    23.8933  -17.5887
            49  C1y C    22.6318  -16.8879
            50  C1y C    21.4404  -17.5887
            51  O1a O    20.2490  -16.8879
            52  O2a O    22.6318  -15.4862
            53  C1y C    23.8232  -14.7854
            54  O2x O    25.0847  -15.4862
            55  C1y C    26.2761  -14.7854
            56  C1y C    26.2761  -13.3838
            57  C1x C    25.0146  -12.6829
            58  C1y C    23.8232  -13.3838
            59  N1a N    22.6318  -12.6829
            60  O1a O    27.4675  -12.6128
            61  C1b C    27.5376  -15.4862
            62  N1a N    27.5376  -16.8879
            63  N1a N    25.0146  -16.8879
            64  N1a N    22.7019  -21.0929
            65  O1a O    20.2490  -22.4945
            66  N1a N    17.7961  -23.8962
            67  O1a O    15.4133  -22.4945
            68  C1b C    15.4133  -19.6912
            69  O1a O    14.2218  -20.3920
            70  S4a S    33.9151  -18.7101
            71  O1d O    33.9151  -20.1117
            72  O1d O    33.9151  -17.3084
            73  O1d O    35.3168  -18.7101
            74  O1d O    32.5135  -18.7101
            75  S4a S    33.9151  -18.7101
            76  O1d O    33.9151  -20.1117
            77  O1d O    33.9151  -17.3084
            78  O1d O    35.3168  -18.7101
            79  O1d O    32.5135  -18.7101
            80  S4a S    33.9151  -18.7101
            81  O1d O    33.9151  -20.1117
            82  O1d O    33.9151  -17.3084
            83  O1d O    35.3168  -18.7101
            84  O1d O    32.5135  -18.7101
            85  S4a S    33.9151  -18.7101
            86  O1d O    33.9151  -20.1117
            87  O1d O    33.9151  -17.3084
            88  O1d O    35.3168  -18.7101
            89  O1d O    32.5135  -18.7101
BOND        88
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     1   7 1 #Up
            8     7   8 1
            9     2   9 1 #Down
            10    3  10 1 #Up
            11    4  11 1 #Down
            12    5  12 1 #Down
            13   13  12 1 #Down
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   16  17 1
            18   17  18 1
            19   13  18 1
            20   14  19 1 #Up
            21   16  20 1 #Up
            22   18  21 1 #Up
            23   17  22 1 #Down
            24   23  22 1 #Down
            25   23  24 1
            26   24  25 1
            27   25  26 1
            28   26  27 1
            29   27  28 1
            30   23  28 1
            31   25  29 1 #Up
            32   29  30 1
            33   26  31 1 #Down
            34   28  32 1 #Down
            35   38  39 1
            36   39  40 1
            37   40  41 1
            38   41  42 1
            39   42  43 1
            40   38  43 1
            41   38  68 1 #Up
            42   68  69 1
            43   39  67 1 #Down
            44   40  66 1 #Up
            45   41  65 1 #Down
            46   42  44 1 #Down
            47   45  44 1 #Down
            48   45  46 1
            49   46  47 1
            50   47  48 1
            51   48  49 1
            52   49  50 1
            53   45  50 1
            54   46  64 1 #Up
            55   48  63 1 #Up
            56   50  51 1 #Up
            57   49  52 1 #Down
            58   53  52 1 #Down
            59   53  54 1
            60   54  55 1
            61   55  56 1
            62   56  57 1
            63   57  58 1
            64   53  58 1
            65   55  61 1 #Up
            66   61  62 1
            67   56  60 1 #Down
            68   58  59 1 #Down
            69   33  34 2
            70   33  35 2
            71   33  36 1
            72   33  37 1
            73   70  71 2
            74   70  72 2
            75   70  73 1
            76   70  74 1
            77   75  76 2
            78   75  77 2
            79   75  78 1
            80   75  79 1
            81   80  81 2
            82   80  82 2
            83   80  83 1
            84   80  84 1
            85   85  86 2
            86   85  87 2
            87   85  88 1
            88   85  89 1
BRACKET     1    12.8100  -24.7100   12.8100  -11.2000
            1    29.4000  -11.2000   29.4000  -24.7100
            1  2
 ORIGINAL  1    1   2   3   4   5   6  12  13  14  15  16  17  18  21  22  23
            1   24  25  26  27  28  32  31  29  30  20  19  11  10   9   7   8
 REPEAT    1   38  39  40  41  42  43  44  45  46  47  48  49  50  51  52  53
            1   54  55  56  57  58  59  60  61  62  63  64  65  66  67  68  69
            2    31.2200  -20.6500   31.2200  -16.5900
            2    36.7500  -16.5900   36.7500  -20.6500
            2  5
 ORIGINAL  2   33  34  35  36  37
 REPEAT    2   70  71  72  73  74  75  76  77  78  79  80  81  82  83  84  85
            2   86  87  88  89

» Japanese version   » Back

KEGG   DRUG: Amikacin
Entry
D02543                      Drug                                   
Name
Amikacin (USP/INN)
Formula
C22H43N5O13
Exact mass
585.2857
Mol weight
585.6025
Structure
Simcomp
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
Same as: C06820
ATC code: D06AX12 J01GB06 S01AA21
Chemical structure group: DG00403
Product (DG00403): D00865<JP/US>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06A ANTIBIOTICS FOR TOPICAL USE
    D06AX Other antibiotics for topical use
     D06AX12 Amikacin
      D02543  Amikacin (USP/INN)
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB06 Amikacin
      D02543  Amikacin (USP/INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA21 Amikacin
      D02543  Amikacin (USP/INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00403  Amikacin
    D02543  Amikacin
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D02543  Amikacin (USP/INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00403  Amikacin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00403  Amikacin
Other DBs
CAS: 37517-28-5
PubChem: 17396714
ChEBI: 2637
PDB-CCD: AKN[PDBj]
LigandBox: D02543
NIKKAJI: J19.345C
LinkDB
KCF data

ATOM        40
            1   C1y C    16.3913  -20.1724
            2   C1y C    16.3913  -21.5733
            3   C1y C    17.5820  -22.2737
            4   C1y C    18.8429  -21.5733
            5   C1y C    18.8429  -20.1724
            6   O2x O    17.5820  -19.4719
            7   O2a O    20.0336  -19.4719
            8   C1y C    21.2244  -18.7714
            9   C1y C    22.4152  -19.4719
            10  C1x C    23.6760  -18.7714
            11  C1y C    23.6760  -17.3705
            12  C1y C    22.4152  -16.6701
            13  C1y C    21.2244  -17.3705
            14  O2a O    22.4152  -15.2692
            15  C1y C    23.6060  -14.5687
            16  C1b C    15.2005  -19.4719
            17  O1a O    14.0097  -20.1724
            18  O1a O    15.2005  -22.2737
            19  N1a N    17.5820  -23.6746
            20  O1a O    20.0336  -22.2737
            21  N1b N    22.4152  -20.8728
            22  C5a C    23.6060  -21.5733
            23  C1c C    24.8668  -20.8728
            24  C1b C    26.0576  -21.5733
            25  C1b C    27.2483  -20.8728
            26  N1a N    28.5091  -21.5733
            27  O2x O    24.8668  -15.2692
            28  C1y C    26.0576  -14.5687
            29  C1y C    26.0576  -13.1678
            30  C1y C    24.7967  -12.4673
            31  C1y C    23.6060  -13.1678
            32  C1b C    27.3184  -15.2692
            33  N1a N    27.3184  -16.6701
            34  O1a O    27.2483  -12.3973
            35  O1a O    24.7967  -11.0664
            36  O1a O    22.4152  -12.4673
            37  O5a O    23.6060  -22.9742
            38  O1a O    24.8668  -19.4719
            39  N1a N    24.7967  -16.6701
            40  O1a O    20.0336  -16.6701
BOND        42
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     5   7 1 #Down
            8     8   7 1 #Down
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14    8  13 1
            15   12  14 1 #Down
            16   15  14 1 #Down
            17    1  16 1 #Up
            18   16  17 1
            19    2  18 1 #Down
            20    3  19 1 #Up
            21    4  20 1 #Down
            22    9  21 1 #Up
            23   21  22 1
            24   22  23 1
            25   23  24 1
            26   24  25 1
            27   25  26 1
            28   15  27 1
            29   27  28 1
            30   28  29 1
            31   29  30 1
            32   30  31 1
            33   15  31 1
            34   28  32 1 #Up
            35   32  33 1
            36   29  34 1 #Down
            37   30  35 1 #Up
            38   31  36 1 #Down
            39   22  37 2
            40   23  38 1 #Up
            41   11  39 1 #Up
            42   13  40 1 #Up

» Japanese version   » Back

KEGG   DRUG: Sisomicin
Entry
D02544                      Drug                                   
Name
Sisomicin (USAN/INN)
Formula
C19H37N5O7
Exact mass
447.2693
Mol weight
447.5264
Structure
Simcomp
Source
Micromonospora inyoensis [TAX:47866]
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
Same as: C00494
ATC code: J01GB08
Chemical structure group: DG00610
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB08 Sisomicin
      D02544  Sisomicin (USAN/INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00610  Sisomicin
    D02544  Sisomicin
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D02544  Sisomicin (USAN/INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00610  Sisomicin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00610  Sisomicin
Other DBs
CAS: 32385-11-8
PubChem: 17396715
ChEBI: 9169
PDB-CCD: SIS[PDBj]
LigandBox: D02544
NIKKAJI: J342.544D
LinkDB
KCF data

ATOM        31
            1   C1y C    24.5413  -19.3649
            2   C1y C    25.7993  -20.0638
            3   C1y C    24.5413  -17.9671
            4   O2a O    23.3531  -20.0638
            5   C1x C    26.9875  -19.3649
            6   N1a N    25.7294  -21.4616
            7   C1y C    25.7993  -17.2682
            8   O1a O    23.3531  -17.2682
            9   C1y C    22.1650  -20.7627
            10  C1y C    26.9875  -17.9671
            11  O2a O    25.7993  -15.8703
            12  C1y C    22.1650  -22.1605
            13  O2x O    20.9070  -20.0638
            14  N1a N    28.3154  -17.6176
            15  C1y C    27.0573  -15.1714
            16  C1y C    20.9070  -22.8594
            17  O1a O    23.3531  -22.8594
            18  C1x C    19.7188  -20.7627
            19  O2x O    28.2455  -15.8703
            20  C1y C    27.0573  -13.7736
            21  C1z C    19.7188  -22.1605
            22  N1b N    20.9768  -24.2572
            23  C2y C    29.4336  -15.1714
            24  C1x C    28.2455  -13.0747
            25  N1a N    25.7993  -13.0747
            26  C1a C    19.9285  -25.2357
            27  C2x C    29.4336  -13.7736
            28  C1b C    30.6917  -15.8703
            29  N1a N    30.6917  -17.2682
            30  C1a C    18.5072  -22.8536
            31  O1a O    18.5064  -21.4605
BOND        33
            1    18  21 1
            2    24  27 1
            3     1   2 1
            4     1   3 1
            5     1   4 1 #Down
            6     2   5 1
            7     2   6 1 #Up
            8     3   7 1
            9     3   8 1 #Up
            10    9   4 1 #Down
            11    5  10 1
            12    7  11 1 #Down
            13    9  12 1
            14    9  13 1
            15   10  14 1 #Up
            16   15  11 1 #Down
            17   12  16 1
            18   12  17 1 #Down
            19   13  18 1
            20   15  19 1
            21   15  20 1
            22   16  21 1
            23   16  22 1 #Up
            24   19  23 1
            25   20  24 1
            26   20  25 1 #Down
            27   22  26 1
            28   23  27 2
            29   23  28 1
            30   28  29 1
            31    7  10 1
            32   21  30 1 #Down
            33   21  31 1 #Up

» Japanese version   » Back

KEGG   DRUG: Isepamicin
Entry
D02545                      Drug                                   
Name
Isepamicin (USAN/INN)
Formula
C22H43N5O12
Exact mass
569.2908
Mol weight
569.6031
Structure
Simcomp
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
ATC code: J01GB11
Chemical structure group: DG00613
Product (DG00613): D01826<JP>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB11 Isepamicin
      D02545  Isepamicin (USAN/INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00613  Isepamicin
    D02545  Isepamicin
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D02545  Isepamicin (USAN/INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00613  Isepamicin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00613  Isepamicin
Other DBs
CAS: 58152-03-7
PubChem: 17396716
LigandBox: D02545
NIKKAJI: J22.232A
LinkDB
KCF data

ATOM        39
            1   C1y C    37.2107  -12.0591
            2   C1y C    37.2107  -10.6570
            3   C1y C    36.0189   -9.9559
            4   C1y C    34.7570  -10.6570
            5   C1y C    34.7570  -12.0591
            6   O2x O    36.0189  -12.7601
            7   O2a O    33.5652  -12.7601
            8   C1y C    33.5652  -14.1622
            9   C1y C    32.3734  -14.8633
            10  C1y C    32.3734  -16.2654
            11  C1y C    33.5652  -16.9665
            12  C1x C    34.7570  -16.2654
            13  C1y C    34.7570  -14.8633
            14  O2a O    31.1115  -16.9665
            15  C1b C    38.4025  -12.7601
            16  O1a O    33.5652   -9.9559
            17  N1a N    36.0189  -14.1622
            18  N1b N    33.5652  -18.3686
            19  O1a O    31.1115  -14.1622
            20  N1a N    38.4025  -14.1622
            21  C1y C    29.8415  -16.3554
            22  O2x O    29.7889  -14.9737
            23  C1x C    28.5180  -14.2893
            24  C1z C    27.3374  -15.0456
            25  C1y C    27.3899  -16.4273
            26  C1y C    28.6609  -17.1117
            27  O1a O    28.7134  -18.4934
            28  O1a O    26.2222  -14.3446
            29  N1b N    26.2092  -17.1836
            30  C1a C    24.9761  -16.5582
            31  O1a O    38.4025   -9.9559
            32  O1a O    36.0189   -8.5538
            33  C5a C    34.7794  -19.0696
            34  C1c C    35.9938  -18.3686
            35  C1b C    37.2080  -19.0696
            36  N1a N    38.4222  -18.3686
            37  O5a O    34.7794  -20.4715
            38  O1a O    35.9938  -16.9667
            39  C1a C    27.3374  -13.4356
BOND        41
            1     8   9 1
            2     9  10 1
            3    10  11 1
            4    21  22 1
            5    22  23 1
            6    23  24 1
            7    24  25 1
            8    25  26 1
            9    26  21 1
            10   11  12 1
            11   26  27 1 #Down
            12   12  13 1
            13   13   8 1
            14   24  28 1 #Up
            15    6   1 1
            16   25  29 1 #Up
            17   10  14 1 #Down
            18   29  30 1
            19    1  15 1 #Up
            20    5   7 1 #Down
            21    4  16 1 #Down
            22   13  17 1 #Up
            23    8   7 1 #Down
            24    2  31 1 #Down
            25   11  18 1 #Up
            26    3  32 1 #Up
            27    1   2 1
            28    9  19 1 #Up
            29    2   3 1
            30   15  20 1
            31    3   4 1
            32   21  14 1 #Down
            33    4   5 1
            34    5   6 1
            35   18  33 1
            36   33  34 1
            37   34  35 1
            38   35  36 1
            39   33  37 2
            40   34  38 1 #Up
            41   24  39 1 #Down

» Japanese version   » Back

KEGG   DRUG: Kanamycin sulfate
Entry
D03262                      Drug                                   
Name
Kanamycin sulfate (JP18);
Kanamycin sulfate (TN)
Formula
C18H36N4O11. xH2SO4
Structure
Simcomp
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
 DG01966  Antitubercular
Remark
Therapeutic category: 6169
ATC code: A07AA08 J01GB04 S01AA24
Chemical structure group: DG00085
Product (DG00085): D00866<JP> D03262<JP>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07A INTESTINAL ANTIINFECTIVES
    A07AA Antibiotics
     A07AA08 Kanamycin
      D03262  Kanamycin sulfate (JP18) <JP>
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB04 Kanamycin
      D03262  Kanamycin sulfate (JP18) <JP>
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA24 Kanamycin
      D03262  Kanamycin sulfate (JP18) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   616  Acting mainly on acid-fast bacteria
    6169  Others
     D03262  Kanamycin sulfate (JP18)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00085  Kanamycin
    D03262  Kanamycin sulfate
  DG01966  Antitubercular
   DG00085  Kanamycin
    D03262  Kanamycin sulfate
Drug classes [BR:br08332]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   D03262  Kanamycin sulfate
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D03262  Kanamycin sulfate (JP18) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D03262  Kanamycin sulfate
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00085  Kanamycin
  DG01966  Antitubercular
   DG00085  Kanamycin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00085  Kanamycin
Other DBs
PubChem: 17397415
LigandBox: D03262
LinkDB
KCF data

ATOM        38
            1   O2a O    33.1997  -15.0547
            2   C1y C    34.3389  -14.3495
            3   O2x O    35.6195  -15.0399
            4   C1y C    36.8285  -14.3345
            5   C1y C    36.8189  -12.9339
            6   C1y C    35.6000  -12.2384
            7   C1y C    34.3910  -12.9506
            8   C1b C    38.0473  -15.0231
            9   N1a N    38.0570  -16.4237
            10  O1a O    33.1701  -12.2587
            11  C1y C    33.2189  -16.4552
            12  C1y C    34.4422  -17.1430
            13  C1x C    34.4592  -18.5461
            14  C1y C    33.2566  -19.2553
            15  C1y C    31.9634  -18.5746
            16  C1y C    32.0129  -17.1777
            17  N1a N    35.6472  -16.4238
            18  N1a N    33.2740  -20.6561
            19  O1a O    30.7960  -16.4914
            20  O2a O    30.8363  -19.2884
            21  C1y C    29.6275  -19.9994
            22  C1y C    29.6364  -21.3994
            23  C1y C    28.4276  -22.1034
            24  C1y C    27.2098  -21.4147
            25  C1y C    27.2010  -20.0148
            26  O2x O    28.4099  -19.3036
            27  O1a O    30.8548  -22.0884
            28  O1a O    26.0003  -22.1191
            29  C1b C    25.9827  -19.3187
            30  N1a N    28.4364  -23.5041
            31  O1a O    24.7730  -20.0302
            32  O1a O    35.5904  -10.8376
            33  O1a O    38.0281  -12.2217
            34  O1d O    37.0499  -21.0939
            35  S4a S    38.4436  -21.0939
            36  O1d O    38.4365  -22.4876
            37  O1d O    39.8373  -21.0939
            38  O1d O    38.4365  -19.7002
BOND        39
            1    16  19 1 #Up
            2     8   9 1
            3    15  20 1 #Down
            4    11   1 1 #Down
            5    21  20 1 #Down
            6     7  10 1 #Down
            7     2   3 1
            8     3   4 1
            9     4   5 1
            10    5   6 1
            11   21  22 1
            12   22  23 1
            13   23  24 1
            14   24  25 1
            15   25  26 1
            16   26  21 1
            17    6   7 1
            18   22  27 1 #Down
            19    7   2 1
            20   24  28 1 #Down
            21   11  12 1
            22   25  29 1 #Up
            23   12  13 1
            24   23  30 1 #Up
            25   13  14 1
            26   29  31 1
            27   14  15 1
            28    6  32 1 #Up
            29   15  16 1
            30    5  33 1 #Down
            31   16  11 1
            32    2   1 1 #Down
            33   12  17 1 #Up
            34    4   8 1 #Up
            35   14  18 1 #Up
            36   34  35 1
            37   35  36 2
            38   35  37 1
            39   35  38 2
BRACKET     1    35.7700  -23.0300   35.7700  -18.9000
            1    41.1600  -18.9000   41.1600  -23.0300
            1  x
 ORIGINAL  1   34  35  36  37  38
 REPEAT    1

» Japanese version   » Back

KEGG   DRUG: Framycetin
Entry
D05140                      Drug                                   
Name
Framycetin (INN);
Fradiomycin B;
Neomycin B;
FRM
Formula
C23H46N6O13
Exact mass
614.3123
Mol weight
614.6437
Structure
Simcomp
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
Same as: C01737
ATC code: D09AA01 R01AX08 S01AA07
Chemical structure group: DG01446
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Biosynthesis
map00524  Neomycin, kanamycin and gentamicin biosynthesis
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D09 MEDICATED DRESSINGS
   D09A MEDICATED DRESSINGS
    D09AA Medicated dressings with antiinfectives
     D09AA01 Framycetin
      D05140  Framycetin (INN)
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AX Other nasal preparations
     R01AX08 Framycetin
      D05140  Framycetin (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA07 Framycetin
      D05140  Framycetin (INN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Fradiomycin
    D05140  Framycetin (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG01446  Framycetin
    D05140  Framycetin
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D05140  Framycetin (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG01446  Framycetin
Other DBs
CAS: 119-04-0
PubChem: 17398248
ChEBI: 7508
PDB-CCD: NMY[PDBj]
LigandBox: D05140
NIKKAJI: J4.458J
LinkDB
KCF data

ATOM        42
            1   C1y C    18.5833  -19.8269
            2   C1y C    18.5833  -21.2133
            3   C1y C    19.8310  -21.9065
            4   C1y C    21.0095  -21.2133
            5   C1y C    21.0095  -19.8269
            6   O2x O    19.8310  -19.1338
            7   O2a O    22.1879  -19.1338
            8   C1y C    24.4062  -17.9554
            9   C1y C    24.8221  -16.6383
            10  O2x O    23.7129  -15.8758
            11  C1y C    22.6038  -16.6383
            12  C1y C    23.0198  -17.9554
            13  O2a O    26.4855  -16.2224
            14  O1a O    26.9013  -18.9951
            15  C1y C    28.0797  -18.3019
            16  C1y C    29.2581  -18.9951
            17  C1x C    30.4365  -18.3019
            18  C1y C    30.4365  -16.9155
            19  C1y C    29.2581  -16.2224
            20  C1y C    28.0797  -16.9155
            21  N1a N    29.2581  -20.3815
            22  N1a N    31.6149  -16.2224
            23  O2a O    29.2581  -14.8360
            24  C1y C    30.4365  -14.1428
            25  O2x O    31.6149  -14.8360
            26  C1y C    32.7934  -14.1428
            27  C1y C    32.7934  -12.7564
            28  C1y C    31.6149  -12.0632
            29  C1y C    30.4365  -12.7564
            30  C1b C    34.0411  -14.7666
            31  N1a N    34.0411  -16.1530
            32  N1a N    29.1887  -12.0632
            33  O1a O    31.6149  -10.6768
            34  O1a O    34.0411  -11.9939
            35  C1b C    21.2868  -16.2224
            36  O1a O    25.2380  -19.1338
            37  O1a O    20.2469  -17.1928
            38  C1b C    17.4049  -19.1338
            39  O1a O    17.4049  -21.9065
            40  N1a N    22.1879  -21.9065
            41  O1a O    19.8310  -23.2929
            42  N1a N    16.1987  -19.8171
BOND        45
            1    25  26 1
            2    26  27 1
            3    27  28 1
            4    28  29 1
            5    29  24 1
            6    26  30 1 #Up
            7    15  14 1 #Down
            8    30  31 1
            9     5   7 1 #Down
            10   29  32 1 #Down
            11   28  33 1 #Up
            12    1   2 1
            13   27  34 1 #Down
            14    2   3 1
            15   11  35 1 #Up
            16   12   7 1 #Down
            17    3   4 1
            18    8  36 1 #Down
            19   15  16 1
            20   35  37 1
            21   16  17 1
            22    1  38 1 #Down
            23   17  18 1
            24    2  39 1 #Down
            25   18  19 1
            26    4  40 1 #Down
            27   19  20 1
            28    3  41 1 #Up
            29   20  15 1
            30    4   5 1
            31   16  21 1 #Up
            32    8   9 1
            33   18  22 1 #Up
            34    9  10 1
            35   19  23 1 #Down
            36   20  13 1 #Up
            37   10  11 1
            38   24  23 1 #Down
            39   11  12 1
            40   12   8 1
            41    5   6 1
            42    9  13 1 #Up
            43    6   1 1
            44   24  25 1
            45   38  42 1

» Japanese version   » Back

KEGG   DRUG: Neomycin palmitate
Entry
D05141                      Drug                                   
Name
Neomycin palmitate (USAN)
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
ATC code: A01AB08 A07AA01 B05CA09 D06AX04 J01GB05 R02AB01 S01AA03 S02AA07 S03AA01
Chemical structure group: DG00003
Product (DG00003): D01618<JP/US>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AB Antiinfectives and antiseptics for local oral treatment
     A01AB08 Neomycin
      D05141  Neomycin palmitate (USAN)
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07A INTESTINAL ANTIINFECTIVES
    A07AA Antibiotics
     A07AA01 Neomycin
      D05141  Neomycin palmitate (USAN)
 B BLOOD AND BLOOD FORMING ORGANS
  B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
   B05C IRRIGATING SOLUTIONS
    B05CA Antiinfectives
     B05CA09 Neomycin
      D05141  Neomycin palmitate (USAN)
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06A ANTIBIOTICS FOR TOPICAL USE
    D06AX Other antibiotics for topical use
     D06AX04 Neomycin
      D05141  Neomycin palmitate (USAN)
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB05 Neomycin
      D05141  Neomycin palmitate (USAN)
 R RESPIRATORY SYSTEM
  R02 THROAT PREPARATIONS
   R02A THROAT PREPARATIONS
    R02AB Antibiotics
     R02AB01 Neomycin
      D05141  Neomycin palmitate (USAN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA03 Neomycin
      D05141  Neomycin palmitate (USAN)
  S02 OTOLOGICALS
   S02A ANTIINFECTIVES
    S02AA Antiinfectives
     S02AA07 Neomycin
      D05141  Neomycin palmitate (USAN)
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03A ANTIINFECTIVES
    S03AA Antiinfectives
     S03AA01 Neomycin
      D05141  Neomycin palmitate (USAN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00003  Neomycin
    D05141  Neomycin palmitate
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D05141  Neomycin palmitate (USAN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00003  Neomycin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00003  Neomycin
Other DBs
CAS: 55298-68-5
PubChem: 47206865
LinkDB

» Japanese version   » Back

KEGG   DRUG: Neomycin undecylenate
Entry
D05142                      Drug                                   
Name
Neomycin undecylenate (USAN)
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
ATC code: A01AB08 A07AA01 B05CA09 D06AX04 J01GB05 R02AB01 S01AA03 S02AA07 S03AA01
Chemical structure group: DG00003
Product (DG00003): D01618<JP/US>
Efficacy
Antibacterial, Antifungal, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AB Antiinfectives and antiseptics for local oral treatment
     A01AB08 Neomycin
      D05142  Neomycin undecylenate (USAN)
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07A INTESTINAL ANTIINFECTIVES
    A07AA Antibiotics
     A07AA01 Neomycin
      D05142  Neomycin undecylenate (USAN)
 B BLOOD AND BLOOD FORMING ORGANS
  B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
   B05C IRRIGATING SOLUTIONS
    B05CA Antiinfectives
     B05CA09 Neomycin
      D05142  Neomycin undecylenate (USAN)
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06A ANTIBIOTICS FOR TOPICAL USE
    D06AX Other antibiotics for topical use
     D06AX04 Neomycin
      D05142  Neomycin undecylenate (USAN)
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB05 Neomycin
      D05142  Neomycin undecylenate (USAN)
 R RESPIRATORY SYSTEM
  R02 THROAT PREPARATIONS
   R02A THROAT PREPARATIONS
    R02AB Antibiotics
     R02AB01 Neomycin
      D05142  Neomycin undecylenate (USAN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA03 Neomycin
      D05142  Neomycin undecylenate (USAN)
  S02 OTOLOGICALS
   S02A ANTIINFECTIVES
    S02AA Antiinfectives
     S02AA07 Neomycin
      D05142  Neomycin undecylenate (USAN)
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03A ANTIINFECTIVES
    S03AA Antiinfectives
     S03AA01 Neomycin
      D05142  Neomycin undecylenate (USAN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00003  Neomycin
    D05142  Neomycin undecylenate
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D05142  Neomycin undecylenate (USAN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00003  Neomycin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00003  Neomycin
Other DBs
CAS: 1406-04-8
PubChem: 47206866
LinkDB

» Japanese version   » Back

KEGG   DRUG: Streptoduocin
Entry
D07432            Mixture   Drug                                   
Name
Streptoduocin (BAN);
Streptomycin sulfate and dihydrostreptomycin sulfate
Component
Dihydrostreptomycin sulfate [DR:D02512], Streptomycin sulfate [DR:D01350]
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
ATC code: J01GA02
Efficacy
Antibacterial
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GA Streptomycins
     J01GA02 Streptoduocin
      D07432  Streptoduocin (BAN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   D07432  Streptoduocin
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D07432  Streptoduocin (BAN)
Other DBs
PubChem: 51091764
LinkDB

» Japanese version   » Back

KEGG   DRUG: Arbekacin
Entry
D07462                      Drug                                   
Name
Arbekacin (INN)
Formula
C22H44N6O10
Exact mass
552.3119
Mol weight
552.619
Structure
Simcomp
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
ATC code: J01GB12
Chemical structure group: DG00614
Product (DG00614): D01523<JP>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB12 Arbekacin
      D07462  Arbekacin (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00614  Arbekacin
    D07462  Arbekacin
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D07462  Arbekacin (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00614  Arbekacin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00614  Arbekacin
Other DBs
CAS: 51025-85-5
PubChem: 51091793
ChEBI: 37922
PDB-CCD: 84G[PDBj]
LigandBox: D07462
NIKKAJI: J33.173B
LinkDB
KCF data

ATOM        38
            1   O2a O    25.3400  -15.1200
            2   C1y C    26.5300  -14.4200
            3   O2x O    27.7900  -15.1200
            4   C1y C    28.9800  -14.4200
            5   C1x C    28.9800  -12.9500
            6   C1x C    27.7200  -12.3200
            7   C1y C    26.5300  -13.0200
            8   C1b C    30.1700  -15.0500
            9   N1a N    30.1700  -16.4500
            10  N1a N    25.3400  -12.3200
            11  C1y C    25.3400  -16.5200
            12  C1y C    26.6000  -17.2200
            13  C1x C    26.6000  -18.6200
            14  C1y C    25.4100  -19.3200
            15  C1y C    24.1500  -18.6200
            16  C1y C    24.1500  -17.2200
            17  N1a N    27.7900  -16.4500
            18  N1b N    25.4100  -20.7200
            19  O1a O    22.9600  -16.5200
            20  O2a O    22.9600  -19.3200
            21  C1y C    21.7700  -20.0900
            22  C1y C    21.7700  -21.4900
            23  C1y C    20.5800  -22.1900
            24  C1y C    19.3200  -21.4900
            25  C1y C    19.3200  -20.0900
            26  O2x O    20.5100  -19.3900
            27  O1a O    22.9600  -22.1200
            28  O1a O    18.1300  -22.1900
            29  C1b C    18.1300  -19.3900
            30  N1a N    20.5800  -23.5900
            31  O1a O    16.9400  -20.0900
            32  C5a C    26.6000  -21.4200
            33  C1c C    27.8600  -20.7200
            34  C1b C    29.0500  -21.4200
            35  C1b C    30.2400  -20.7200
            36  N1a N    31.4300  -21.4200
            37  O5a O    26.6000  -22.8200
            38  O1a O    27.8600  -19.3200
BOND        40
            1     4   5 1
            2    12  17 1 #Up
            3     5   6 1
            4    14  18 1 #Up
            5     6   7 1
            6    16  19 1 #Up
            7     7   2 1
            8    15  20 1 #Down
            9    11   1 1 #Down
            10   21  20 1 #Down
            11    4   8 1 #Up
            12    2   1 1 #Down
            13    8   9 1
            14    7  10 1 #Down
            15   21  22 1
            16   22  23 1
            17   23  24 1
            18   24  25 1
            19   25  26 1
            20   26  21 1
            21   22  27 1 #Down
            22   24  28 1 #Down
            23   25  29 1 #Up
            24   23  30 1 #Up
            25    2   3 1
            26   29  31 1
            27    3   4 1
            28   18  32 1
            29   11  12 1
            30   32  33 1
            31   12  13 1
            32   33  34 1
            33   13  14 1
            34   34  35 1
            35   14  15 1
            36   35  36 1
            37   15  16 1
            38   32  37 2
            39   16  11 1
            40   33  38 1 #Up

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KEGG   DRUG: Bekanamycin
Entry
D07497                      Drug                                   
Name
Bekanamycin (INN);
Kanamycin B
Formula
C18H37N5O10
Exact mass
483.254
Mol weight
483.5139
Structure
Simcomp
Source
Streptomyces kanamyceticus [TAX:1967]
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
Same as: C00825
ATC code: J01GB13
Chemical structure group: DG00615
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Biosynthesis
map00524  Neomycin, kanamycin and gentamicin biosynthesis
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB13 Bekanamycin
      D07497  Bekanamycin (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00615  Bekanamycin
    D07497  Bekanamycin
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D07497  Bekanamycin (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00615  Bekanamycin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00615  Bekanamycin
Other DBs
CAS: 4696-76-8
PubChem: 51091822
ChEBI: 28098
PDB-CCD: 9CS[PDBj]
LigandBox: D07497
NIKKAJI: J8.763G
LinkDB
KCF data

ATOM        33
            1   C1y C    29.6800  -15.1200
            2   C1y C    29.6800  -13.7200
            3   C1y C    28.4200  -13.0200
            4   C1y C    27.2300  -13.7200
            5   C1y C    27.2300  -15.1200
            6   O2x O    28.4200  -15.8200
            7   O2a O    26.0400  -15.8200
            8   C1y C    26.0400  -17.2200
            9   C1y C    24.7800  -17.9200
            10  C1y C    24.7800  -19.3200
            11  C1y C    26.0400  -20.0200
            12  C1x C    27.2300  -19.3200
            13  C1y C    27.2300  -17.9200
            14  O2a O    23.5900  -20.0200
            15  C1b C    30.8700  -15.8200
            16  N1a N    26.0400  -13.0200
            17  N1a N    28.4200  -17.2200
            18  N1a N    26.0400  -21.4200
            19  O1a O    23.5900  -17.2200
            20  N1a N    30.8700  -17.2200
            21  C1y C    22.4000  -20.7200
            22  O2x O    21.1400  -20.0200
            23  C1y C    19.9500  -20.7200
            24  C1y C    19.9500  -22.1200
            25  C1y C    21.1400  -22.8200
            26  C1y C    22.4000  -22.1200
            27  O1a O    30.8700  -13.0200
            28  O1a O    28.4200  -11.6200
            29  C1b C    18.7600  -20.0200
            30  O1a O    17.5000  -20.7200
            31  O1a O    18.6900  -22.8200
            32  N1a N    21.1400  -24.2200
            33  O1a O    23.6600  -22.8200
BOND        35
            1    26  21 1
            2    11  12 1
            3    12  13 1
            4    13   8 1
            5     6   1 1
            6    10  14 1 #Down
            7     1  15 1 #Up
            8     5   7 1 #Down
            9     4  16 1 #Down
            10   13  17 1 #Up
            11    8   7 1 #Down
            12    2  27 1 #Down
            13   11  18 1 #Up
            14    3  28 1 #Up
            15    1   2 1
            16    9  19 1 #Up
            17    2   3 1
            18   15  20 1
            19    3   4 1
            20   23  29 1 #Up
            21   29  30 1
            22   21  14 1 #Down
            23   24  31 1 #Down
            24    4   5 1
            25   25  32 1 #Up
            26    5   6 1
            27   26  33 1 #Down
            28    8   9 1
            29    9  10 1
            30   10  11 1
            31   21  22 1
            32   22  23 1
            33   23  24 1
            34   24  25 1
            35   25  26 1

» Japanese version   » Back

KEGG   DRUG: Dibekacin
Entry
D07811                      Drug                                   
Name
Dibekacin (INN)
Formula
C18H37N5O8
Exact mass
451.2642
Mol weight
451.5151
Structure
Simcomp
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
ATC code: J01GB09 S01AA29
Chemical structure group: DG00611
Product (DG00611): D01753<JP>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB09 Dibekacin
      D07811  Dibekacin (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA29 Dibekacin
      D07811  Dibekacin (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00611  Dibekacin
    D07811  Dibekacin
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D07811  Dibekacin (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00611  Dibekacin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00611  Dibekacin
Other DBs
CAS: 34493-98-6
PubChem: 96024508
ChEBI: 37945
PDB-CCD: 84D[PDBj]
LigandBox: D07811
NIKKAJI: J94.714H
LinkDB
KCF data

ATOM        31
            1   C1y C    18.1300  -19.9500
            2   C1y C    18.1300  -21.3500
            3   C1y C    19.3200  -22.0500
            4   C1y C    20.5100  -21.3500
            5   C1y C    20.5100  -19.9500
            6   O2x O    19.3200  -19.2500
            7   N1a N    19.3200  -23.4500
            8   O1a O    16.8700  -22.0500
            9   O1a O    21.7700  -22.0500
            10  O2a O    21.7700  -19.2500
            11  C1y C    22.9600  -18.5500
            12  C1y C    24.1500  -19.2500
            13  C1x C    25.3400  -18.4800
            14  C1y C    25.3400  -17.0800
            15  C1y C    24.1500  -16.4500
            16  C1y C    22.9600  -17.1500
            17  N1a N    24.1500  -20.6500
            18  N1a N    26.6000  -16.3800
            19  O2a O    24.1500  -15.0500
            20  O1a O    21.7000  -16.4500
            21  C1y C    25.3400  -14.2800
            22  O2x O    26.6000  -14.9800
            23  C1y C    27.7900  -14.2800
            24  C1x C    27.7900  -12.8800
            25  C1x C    26.5300  -12.1800
            26  C1y C    25.3400  -12.8800
            27  C1b C    28.9800  -14.9800
            28  N1a N    28.9800  -16.3800
            29  N1a N    24.1500  -12.2500
            30  C1b C    16.8700  -19.2500
            31  O1a O    15.6800  -19.9500
BOND        33
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4    11  12 1
            5    12  13 1
            6    13  14 1
            7    14  15 1
            8    15  16 1
            9    16  11 1
            10    4   5 1
            11   12  17 1 #Up
            12    5   6 1
            13   14  18 1 #Up
            14    6   1 1
            15   15  19 1 #Down
            16   16  20 1 #Up
            17    3   7 1 #Up
            18   21  19 1 #Down
            19    2   8 1 #Down
            20    4   9 1 #Down
            21   21  22 1
            22   22  23 1
            23   23  24 1
            24   24  25 1
            25   25  26 1
            26   26  21 1
            27    5  10 1 #Down
            28   23  27 1 #Up
            29   27  28 1
            30   11  10 1 #Down
            31   26  29 1 #Down
            32    1  30 1 #Up
            33   30  31 1

» Japanese version   » Back

KEGG   DRUG: Framycetin sulfate
Entry
D07994                      Drug                                   
Name
Framycetin sulfate;
Neomycin B sulfate;
Isofra (TN)
Formula
C23H46N6O13. H2SO4
Exact mass
712.2797
Mol weight
712.7222
Structure
Simcomp
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
ATC code: D09AA01 R01AX08 S01AA07
Chemical structure group: DG01446
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D09 MEDICATED DRESSINGS
   D09A MEDICATED DRESSINGS
    D09AA Medicated dressings with antiinfectives
     D09AA01 Framycetin
      D07994  Framycetin sulfate
 R RESPIRATORY SYSTEM
  R01 NASAL PREPARATIONS
   R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
    R01AX Other nasal preparations
     R01AX08 Framycetin
      D07994  Framycetin sulfate
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA07 Framycetin
      D07994  Framycetin sulfate
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG01446  Framycetin
    D07994  Framycetin sulfate
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D07994  Framycetin sulfate
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG01446  Framycetin
Other DBs
CAS: 28002-70-2
PubChem: 96024688
LigandBox: D07994
NIKKAJI: J262.631D
LinkDB
KCF data

ATOM        47
            1   C1y C    20.5722  -21.3409
            2   C1y C    20.5722  -22.7403
            3   C1y C    21.8317  -23.4399
            4   C1y C    23.0211  -22.7403
            5   C1y C    23.0211  -21.3409
            6   O2x O    21.8317  -20.6412
            7   O2a O    24.2106  -20.6412
            8   C1y C    26.4496  -19.5217
            9   C1y C    26.8695  -18.1923
            10  O2x O    25.7499  -17.4226
            11  C1y C    24.6304  -18.1923
            12  C1y C    25.0503  -19.5217
            13  O2a O    28.4787  -17.7724
            14  O1a O    28.8986  -20.5012
            15  C1y C    30.0880  -19.8015
            16  C1y C    31.2775  -20.5012
            17  C1x C    32.4670  -19.8015
            18  C1y C    32.4670  -18.4721
            19  C1y C    31.2775  -17.7724
            20  C1y C    30.0880  -18.4721
            21  N1a N    31.2775  -21.9006
            22  N1a N    33.6565  -17.7724
            23  O2a O    31.2775  -16.3731
            24  C1y C    32.4670  -15.6734
            25  O2x O    33.6565  -16.3731
            26  C1y C    34.7760  -15.6734
            27  C1y C    34.7760  -14.2740
            28  C1y C    33.6565  -13.5743
            29  C1y C    32.4670  -14.2740
            30  C1b C    36.0354  -16.3031
            31  N1a N    36.0354  -17.7025
            32  N1a N    31.2075  -13.5743
            33  O1a O    33.6565  -12.2449
            34  O1a O    36.0354  -13.5043
            35  C1b C    23.3010  -17.7724
            36  O1a O    27.2893  -20.6412
            37  O1a O    22.2515  -18.7520
            38  C1b C    19.4527  -20.6412
            39  O1a O    19.4527  -23.4399
            40  N1a N    24.2106  -23.4399
            41  O1a O    21.8317  -24.8393
            42  N1a N    18.1933  -21.3409
            43  S4a S    36.0434  -23.0244
            44  O1d O    36.0434  -21.6250
            45  O1d O    36.0434  -24.4238
            46  O1d O    37.4428  -23.0244
            47  O1d O    34.6440  -23.0244
BOND        49
            1    25  26 1
            2    26  27 1
            3    27  28 1
            4    28  29 1
            5    29  24 1
            6    26  30 1 #Up
            7    15  14 1 #Down
            8    30  31 1
            9     5   7 1 #Down
            10   29  32 1 #Down
            11   28  33 1 #Up
            12    1   2 1
            13   27  34 1 #Down
            14    2   3 1
            15   11  35 1 #Up
            16   12   7 1 #Down
            17    3   4 1
            18    8  36 1 #Down
            19   15  16 1
            20   35  37 1
            21   16  17 1
            22    1  38 1 #Down
            23   17  18 1
            24    2  39 1 #Down
            25   18  19 1
            26    4  40 1 #Down
            27   19  20 1
            28    3  41 1 #Up
            29   20  15 1
            30    4   5 1
            31   16  21 1 #Up
            32    8   9 1
            33   18  22 1 #Up
            34    9  10 1
            35   19  23 1 #Down
            36   20  13 1 #Up
            37   10  11 1
            38   24  23 1 #Down
            39   11  12 1
            40   12   8 1
            41    5   6 1
            42    9  13 1 #Up
            43    6   1 1
            44   24  25 1
            45   38  42 1
            46   43  44 2
            47   43  45 2
            48   43  46 1
            49   43  47 1

» Japanese version   » Back

KEGG   DRUG: Gentamicin
Entry
D08013                      Drug                                   
Name
Gentamicin (BAN);
Gentamicin (TN)
Formula
C21H43N5O7
Exact mass
477.3162
Mol weight
477.5954
Structure
Simcomp
Source
Micromonospora echinospora [TAX:1877]
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
ATC code: D06AX07 J01GB03 S01AA11 S02AA14 S03AA06
Chemical structure group: DG00401
Product (DG00401): D01063<JP/US>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06A ANTIBIOTICS FOR TOPICAL USE
    D06AX Other antibiotics for topical use
     D06AX07 Gentamicin
      D08013  Gentamicin (BAN)
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB03 Gentamicin
      D08013  Gentamicin (BAN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA11 Gentamicin
      D08013  Gentamicin (BAN)
  S02 OTOLOGICALS
   S02A ANTIINFECTIVES
    S02AA Antiinfectives
     S02AA14 Gentamicin
      D08013  Gentamicin (BAN)
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03A ANTIINFECTIVES
    S03AA Antiinfectives
     S03AA06 Gentamicin
      D08013  Gentamicin (BAN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00401  Gentamicin
    D08013  Gentamicin
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D08013  Gentamicin (BAN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00401  Gentamicin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00401  Gentamicin
Other DBs
CAS: 1403-66-3
PubChem: 96024706
LigandBox: D08013
NIKKAJI: J4.074F
LinkDB
KCF data

ATOM        33
            1   C1y C    25.4100  -17.7100
            2   C1y C    23.3800  -18.3400
            3   O2a O    25.6900  -18.7600
            4   C1y C    26.6000  -18.1300
            5   C1y C    22.6100  -17.3600
            6   O1a O    22.5400  -19.1100
            7   C1y C    25.9700  -19.8100
            8   C1x C    25.5500  -17.0800
            9   N1a N    27.5100  -17.5700
            10  O2a O    21.7000  -17.8500
            11  C1y C    23.8700  -17.7100
            12  C1y C    26.6700  -20.7900
            13  O2x O    27.4400  -19.8100
            14  C1y C    21.4200  -16.8000
            15  N1a N    24.2900  -16.2400
            16  C1y C    28.7700  -20.2300
            17  O1a O    25.9000  -21.5600
            18  C1x C    28.9800  -19.3200
            19  O2x O    20.9300  -15.4700
            20  C1y C    20.1600  -16.3800
            21  C1z C    29.9600  -20.6500
            22  N1b N    28.4900  -21.4900
            23  C1y C    18.6200  -16.3800
            24  C1x C    18.1300  -17.0100
            25  N1a N    19.8800  -17.5700
            26  C1a C    30.8700  -20.0900
            27  O1a O    30.5200  -21.5600
            28  C1a C    29.5400  -22.6100
            29  C1x C    17.4300  -16.0300
            30  C1c C    18.8300  -14.7700
            31  N1b N    19.8800  -14.4900
            32  C1a C    18.0600  -14.0000
            33  C1a C    20.4400  -13.2300
BOND        35
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     4   8 1
            8     4   9 1
            9     5  10 1
            10    5  11 1
            11    7  12 1
            12    7  13 1
            13   10  14 1
            14   11  15 1
            15   12  16 1
            16   12  17 1
            17   13  18 1
            18   14  19 1
            19   14  20 1
            20   16  21 1
            21   16  22 1
            22   19  23 1
            23   20  24 1
            24   20  25 1
            25   21  26 1
            26   21  27 1
            27   22  28 1
            28   23  29 1
            29   23  30 1
            30   30  31 1
            31   30  32 1
            32   31  33 1
            33    8  11 1
            34   18  21 1
            35   24  29 1

» Japanese version   » Back

KEGG   DRUG: Neomycin
Entry
D08260                      Drug                                   
Name
Neomycin (INN);
Fradiomycin;
Neomycin;
Kaomycine (TN)
Formula
C12H25N4O5R
Structure
Simcomp
Source
Streptomyces Fradiae [TAX:1906]
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
Same as: C00384
ATC code: A01AB08 A07AA01 B05CA09 D06AX04 J01GB05 R02AB01 S01AA03 S02AA07 S03AA01
Chemical structure group: DG00003
Product (DG00003): D01618<JP/US>
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Comment
R: See Neomycin [CPD:C00384]
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A01 STOMATOLOGICAL PREPARATIONS
   A01A STOMATOLOGICAL PREPARATIONS
    A01AB Antiinfectives and antiseptics for local oral treatment
     A01AB08 Neomycin
      D08260  Neomycin (INN)
  A07 ANTIDIARRHEALS, INTESTINAL ANTIINFLAMMATORY/ANTIINFECTIVE AGENTS
   A07A INTESTINAL ANTIINFECTIVES
    A07AA Antibiotics
     A07AA01 Neomycin
      D08260  Neomycin (INN)
 B BLOOD AND BLOOD FORMING ORGANS
  B05 BLOOD SUBSTITUTES AND PERFUSION SOLUTIONS
   B05C IRRIGATING SOLUTIONS
    B05CA Antiinfectives
     B05CA09 Neomycin
      D08260  Neomycin (INN)
 D DERMATOLOGICALS
  D06 ANTIBIOTICS AND CHEMOTHERAPEUTICS FOR DERMATOLOGICAL USE
   D06A ANTIBIOTICS FOR TOPICAL USE
    D06AX Other antibiotics for topical use
     D06AX04 Neomycin
      D08260  Neomycin (INN)
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB05 Neomycin
      D08260  Neomycin (INN)
 R RESPIRATORY SYSTEM
  R02 THROAT PREPARATIONS
   R02A THROAT PREPARATIONS
    R02AB Antibiotics
     R02AB01 Neomycin
      D08260  Neomycin (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA03 Neomycin
      D08260  Neomycin (INN)
  S02 OTOLOGICALS
   S02A ANTIINFECTIVES
    S02AA Antiinfectives
     S02AA07 Neomycin
      D08260  Neomycin (INN)
  S03 OPHTHALMOLOGICAL AND OTOLOGICAL PREPARATIONS
   S03A ANTIINFECTIVES
    S03AA Antiinfectives
     S03AA01 Neomycin
      D08260  Neomycin (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00003  Neomycin
    D08260  Neomycin
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D08260  Neomycin (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00003  Neomycin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00003  Neomycin
Other DBs
CAS: 1404-04-2
PubChem: 96024948
ChEBI: 7507
NIKKAJI: J872I
LinkDB
KCF data

ATOM        22
            1   R   R    20.5100  -18.6200
            2   O1a O    20.5800  -21.4200
            3   C1y C    21.8400  -20.7200
            4   C1y C    23.0300  -21.4200
            5   C1x C    24.2200  -20.7200
            6   C1y C    24.2200  -19.3200
            7   C1y C    23.0300  -18.6200
            8   C1y C    21.8400  -19.3200
            9   N1a N    23.0300  -22.8200
            10  N1a N    25.4100  -18.6200
            11  O2a O    23.0300  -17.2200
            12  C1y C    24.2200  -16.5200
            13  O2x O    25.4100  -17.2200
            14  C1y C    26.6000  -16.5200
            15  C1y C    26.6000  -15.1200
            16  C1y C    25.4100  -14.4200
            17  C1y C    24.2200  -15.1200
            18  C1b C    27.8600  -17.1500
            19  N1a N    27.8600  -18.5500
            20  N1a N    22.9600  -14.4200
            21  O1a O    25.4100  -13.0200
            22  O1a O    27.8600  -14.3500
BOND        23
            1    13  14 1
            2    14  15 1
            3    15  16 1
            4    16  17 1
            5    17  12 1
            6    14  18 1 #Up
            7     3   2 1 #Down
            8    18  19 1
            9    17  20 1 #Down
            10   16  21 1 #Up
            11   15  22 1 #Down
            12    3   4 1
            13    4   5 1
            14    5   6 1
            15    6   7 1
            16    7   8 1
            17    8   3 1
            18    4   9 1 #Up
            19    6  10 1 #Up
            20    7  11 1 #Down
            21    8   1 1 #Up
            22   12  11 1 #Down
            23   12  13 1

» Japanese version   » Back

KEGG   DRUG: Netilmicin
Entry
D08268                      Drug                                   
Name
Netilmicin (INN);
Netira (TN)
Formula
C21H41N5O7
Exact mass
475.3006
Mol weight
475.5795
Structure
Simcomp
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
Same as: C07657
ATC code: J01GB07 S01AA23
Chemical structure group: DG00609
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB07 Netilmicin
      D08268  Netilmicin (INN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AA Antibiotics
     S01AA23 Netilmicin
      D08268  Netilmicin (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00609  Netilmicin
    D08268  Netilmicin
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D08268  Netilmicin (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00609  Netilmicin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00609  Netilmicin
Other DBs
CAS: 56391-56-1
PubChem: 96024955
ChEBI: 7528
LigandBox: D08268
NIKKAJI: J236.025J
LinkDB
KCF data

ATOM        33
            1   C1y C    24.1500  -18.1300
            2   C1y C    25.3400  -18.8300
            3   C1y C    24.1500  -16.7300
            4   O2a O    22.8900  -18.8300
            5   C1x C    26.5300  -18.1300
            6   N1b N    25.3400  -20.2300
            7   C1y C    25.3400  -16.0300
            8   O1a O    22.8900  -16.0300
            9   C1y C    21.7000  -19.5300
            10  C1y C    26.5300  -16.7300
            11  C1b C    26.5300  -20.9300
            12  O2a O    25.3400  -14.6300
            13  C1y C    21.7000  -20.9300
            14  O2x O    20.5100  -18.8300
            15  N1a N    27.8600  -16.3800
            16  C1a C    26.6000  -22.3300
            17  C1y C    26.6000  -13.9300
            18  C1y C    20.5100  -21.6300
            19  O1a O    22.8900  -21.6300
            20  C1x C    19.2500  -19.5300
            21  O2x O    27.7900  -14.6300
            22  C1y C    26.6000  -12.5300
            23  C1z C    19.2500  -20.9300
            24  N1b N    20.5100  -23.0300
            25  C2y C    28.9800  -13.9300
            26  C1x C    27.7900  -11.8300
            27  N1a N    25.4100  -11.8300
            28  C1a C    19.5300  -24.0100
            29  C2x C    28.9800  -12.5300
            30  C1b C    30.2400  -14.6300
            31  N1a N    30.2400  -16.0300
            32  C1a C    18.0600  -21.6300
            33  O1a O    18.0600  -20.2300
BOND        35
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     2   6 1 #Up
            6     3   7 1
            7     3   8 1 #Up
            8     9   4 1 #Down
            9     5  10 1
            10    6  11 1
            11    7  12 1 #Down
            12    9  13 1
            13    9  14 1
            14   10  15 1 #Up
            15   11  16 1
            16   17  12 1 #Down
            17   13  18 1
            18   13  19 1 #Down
            19   14  20 1
            20   17  21 1
            21   17  22 1
            22   18  23 1
            23   18  24 1 #Up
            24   21  25 1
            25   22  26 1
            26   22  27 1 #Down
            27   24  28 1
            28   25  29 2
            29   25  30 1
            30   30  31 1
            31    7  10 1
            32   20  23 1
            33   26  29 1
            34   23  32 1
            35   23  33 1 #Up

» Japanese version   » Back

KEGG   DRUG: Ribostamycin
Entry
D08478                      Drug                                   
Name
Ribostamycin (INN)
Formula
C17H34N4O10
Exact mass
454.2275
Mol weight
454.4727
Structure
Simcomp
Source
Streptomyces ribosidificus [TAX:80859]
Class
Antibacterial
 DG01447  Aminoglycoside antibiotic
Remark
Same as: C01759
ATC code: J01GB10
Chemical structure group: DG00612
Efficacy
Antibacterial, Protein biosynthesis inhibitor
Target
30S ribosomal subunit
  Pathway
ko03010  Ribosome
Interaction
Biosynthesis
map00524  Neomycin, kanamycin and gentamicin biosynthesis
Structure map
map07021  Aminoglycosides
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01G AMINOGLYCOSIDE ANTIBACTERIALS
    J01GB Other aminoglycosides
     J01GB10 Ribostamycin
      D08478  Ribostamycin (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00612  Ribostamycin
    D08478  Ribostamycin
Antimicrobials [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    D08478  Ribostamycin (INN)
Drug groups [BR:br08330]
 Antibacterial
  DG01447  Aminoglycoside antibiotic
   DG00612  Ribostamycin
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Protein biosynthesis inhibitor
   Aminoglycoside
    DG00612  Ribostamycin
Other DBs
CAS: 25546-65-0
PubChem: 96025164
ChEBI: 45257
PDB-CCD: RIO[PDBj]
LigandBox: D08478
NIKKAJI: J20.066B
LinkDB
KCF data

ATOM        31
            1   C1y C    24.9900  -19.3200
            2   C1y C    24.9900  -20.7200
            3   C1y C    26.1800  -21.4200
            4   C1x C    27.3700  -20.7200
            5   C1y C    27.3700  -19.3200
            6   C1y C    26.1800  -18.6200
            7   O2a O    23.5200  -18.6200
            8   C1y C    21.4900  -20.3700
            9   C1y C    21.9100  -19.0400
            10  O2x O    20.7900  -18.2700
            11  C1y C    19.6700  -19.0400
            12  C1y C    20.0900  -20.3700
            13  C1b C    18.3400  -18.6200
            14  O1a O    17.2900  -19.5300
            15  O1a O    22.3300  -21.4900
            16  O1a O    19.2500  -21.4900
            17  O1a O    24.0800  -21.4900
            18  N1a N    26.1800  -22.8200
            19  N1a N    28.6300  -18.6200
            20  O2a O    26.1800  -17.2200
            21  C1y C    27.4400  -16.5200
            22  O2x O    28.6300  -17.2200
            23  C1y C    29.8200  -16.5200
            24  C1y C    29.8200  -15.1900
            25  C1y C    28.6300  -14.4900
            26  C1y C    27.4400  -15.1900
            27  C1b C    31.0100  -17.2200
            28  N1a N    31.0100  -18.6200
            29  O1a O    31.0100  -14.4900
            30  O1a O    28.6300  -13.0900
            31  N1a N    26.1800  -14.4900
BOND        33
            1     2  17 1 #Down
            2     1   2 1
            3     3  18 1 #Up
            4     2   3 1
            5     5  19 1 #Up
            6     3   4 1
            7     6  20 1 #Down
            8     4   5 1
            9    21  20 1 #Down
            10    8   9 1
            11    9  10 1
            12   10  11 1
            13   11  12 1
            14   12   8 1
            15   21  22 1
            16   22  23 1
            17   23  24 1
            18   24  25 1
            19   25  26 1
            20   26  21 1
            21    5   6 1
            22   23  27 1 #Up
            23   11  13 1 #Up
            24   27  28 1
            25    6   1 1
            26   24  29 1 #Down
            27   13  14 1
            28   25  30 1 #Up
            29    9   7 1 #Up
            30   26  31 1 #Down
            31    8  15 1 #Down
            32    1   7 1 #Up
            33   12  16 1 #Down

» Japanese version   » Back

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