Acidovorax sp. KKS102: C380_03730
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Entry
C380_03730 CDS
T02290
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ack
Acidovorax sp. KKS102
Pathway
ack00300
Lysine biosynthesis
ack00550
Peptidoglycan biosynthesis
ack01100
Metabolic pathways
ack01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ack00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
C380_03730
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
C380_03730
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
C380_03730
Enzymes [BR:
ack01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
C380_03730
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LPD22
Motif
Other DBs
NCBI-ProteinID:
AFU44469
UniProt:
K0I021
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Position
822313..823779
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AA seq
488 aa
AA seq
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MGMNSFEPVMTLQQAWALLQPSIPAARLVGDGATPLARVHTDTRTLQPGDLFVALKGERF
DANAFLADARAGGAAAAIAHGGLEAAGLSGIEVPNSLAALGALATGWRAQFHLPLIGVTG
SNGKTTVTQMIASILRAWQGDAAFATQGNFNNDIGVPLMLMRLRASHRAAVIEMGMNHPG
EIATLAAMAQPTVALVNNAQREHLEFMHTVEAVARENGSVFASLPADGVAVFPAGDAYTS
LWQSLAMERPGRRTVTFGEGGDVRCAQATWERGAWAVTLVTPRGEITTRLHIAGRHNVSN
ALAATACTLAAGAPVAAIAQGLRDFTPVKGRSRAFSVSVAGRDITVVDDTYNANPDSMHA
AIQVLAELPGPQLLVMGDMGEVGDQGPQFHAEAGALAREAGIPTMFVLGAQSVHAASAYG
DGARHFNEMAALQDAVRKALPTVGSVLVKGSRFMKMEQVVEAISAAALPAEQQQRPINPR
EGHHGATH
NT seq
1467 nt
NT seq
+upstream
nt +downstream
nt
atgggcatgaacagttttgaacccgtcatgactctgcagcaagcctgggcgctgctgcag
ccaagtatccctgctgcccgtctggtgggcgatggcgccactccgctggcgcgcgtgcac
accgacacgcgcacgttgcagccgggcgatttgtttgtggccctcaagggcgagcgtttt
gatgccaacgcctttttggccgacgcccgggctggcggcgctgcagccgctattgcgcac
ggtggcctggaagcagcgggcttgtccggcatcgaagtgcccaacagcctggctgcgctg
ggcgcactggccaccggctggcgcgcgcaatttcatctgccgctgatcggcgtgacgggc
agcaacggcaagaccacggtgacgcagatgattgcgtccattctgcgtgcctggcagggc
gacgccgcatttgccacgcagggcaatttcaacaacgacatcggtgtgccgctgatgctg
atgcgcctgcgcgccagccaccgcgccgccgtgatcgagatgggcatgaaccaccctggc
gagatcgccacactggcggccatggcccagcccacggtggccttggtcaacaacgcgcag
cgtgagcatctggaattcatgcacaccgtagaggccgtggcccgcgagaacggttcggtg
tttgccagcctgccggccgatggtgtggccgtattcccggcaggggatgcgtacacgagc
ctgtggcaatcgcttgccatggagcggcccggccgccgtacggtgacgtttggtgagggc
ggcgacgtccgctgcgcgcaggccacctgggagcgcggcgcctgggcggtcaccctagtc
acgccacgcggcgagatcaccacccgtctgcacatcgcaggccgccacaacgtgtccaac
gcgctggcggccacggcgtgcacgctggcagcgggtgcaccggttgcggccattgcccag
gggctgcgcgacttcaccccggtcaagggccgttcgcgcgcgttcagcgtgtccgttgca
ggccgcgacatcacggtggtggacgacacctacaacgccaaccccgattccatgcacgcg
gccatccaggtgctggctgaactgccaggcccgcaactgctggtgatgggcgacatgggc
gaggtgggcgaccagggcccgcagttccatgccgaggcgggcgcactggcccgtgaggcg
ggcatccccacgatgtttgtgctgggtgcgcagtcggtgcacgccgcatcggcctatggc
gatggggcccggcatttcaacgagatggccgccctgcaggatgccgtgcgcaaagccctg
cccacggtgggcagtgtgctggtcaagggatcgcgattcatgaagatggaacaggtggtc
gaggcgatcagcgccgccgcactgcccgcagaacaacaacaaaggccgatcaacccacgg
gagggacaccatggcgcaacgcattga
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