Actinoplanes sp. NBRC 14428: Asp14428_23740
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Entry
Asp14428_23740 CDS
T08315
Symbol
murF_1
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
actr
Actinoplanes sp. NBRC 14428
Pathway
actr00300
Lysine biosynthesis
actr00550
Peptidoglycan biosynthesis
actr01100
Metabolic pathways
actr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
actr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Asp14428_23740 (murF_1)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Asp14428_23740 (murF_1)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Asp14428_23740 (murF_1)
Enzymes [BR:
actr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Asp14428_23740 (murF_1)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
SFXNs
Motif
Other DBs
NCBI-ProteinID:
BCJ50899
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Position
complement(2570397..2571824)
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AA seq
475 aa
AA seq
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MRVVARVPAMIPLTLAEIAAAVRGTVCDGDPEITVTGPLRYETAKVEPGGMFAAFAGARR
DGHEFAARVVADGAAAVLASRPVGVPAVVVGDVRDACQRLAAELVTRLPGVHRIGVTGSS
GKTSTKDLLGQVLGRLGPTVAPPGNRNNELGVPETVLLTTAETRFLVAELGARHVGDIAA
LMPIVRPHTGVVLGVGTAHLGEFGSREAIARAKAELVEALPADGLAVLNADDPVVAAMAG
RTAARVVTFGRHSTARIRAERVMLDGAARARFVLRTPAGSAEVALRLHGEHFVTAALAAA
AVALDHTHDVWLVADALSAATPRSEGRMRLSERPDGVTVLDDAYNANPESMVAGLRALVA
VAAGRRRTVAVLGQMNELGEGSATAHAEVGRAAVRLGVDVVVAVGNRDAAGYGGVYAPDR
ETAAAVLRGLIEPGDVVLVKASHGLGLSAVAEALIDADQIARSAPPSTGTEMPVR
NT seq
1428 nt
NT seq
+upstream
nt +downstream
nt
gtgcgcgtggtggctagggttccggccatgattcccctgactctcgccgagattgctgcg
gccgtacgcggaactgtgtgtgacggtgacccggagatcaccgtgaccggtccgctgcgt
tacgagaccgccaaggtcgagccgggcgggatgttcgccgctttcgccggagcccgccgc
gacggccacgagttcgccgcgcgggtcgtcgcggacggtgccgccgccgtgctggcgtcc
cggcccgtcggcgtcccggccgtggtcgtcggcgacgtgcgcgacgcctgccagcggctc
gccgccgagctcgtcacgcggctgcccggggtgcaccggatcggcgtgaccggctcgtcc
ggcaagacgtccacgaaggacctgctcgggcaggtcctgggccggctggggccgaccgtg
gcgccgcccggcaaccgcaacaacgagctgggcgtgcccgagaccgtgctgctcaccacc
gcggagacccggttcctcgtcgccgagctgggcgcccggcacgtgggtgacatcgccgcg
ctgatgccgatcgtccggccgcacaccggggtggtgctcggcgtcggcaccgcgcacctc
ggcgagttcggcagccgggaggcgatcgcgcgggcgaaggccgagctggtggaggcgctg
cccgcggacggcctggcggtgctcaacgcggacgacccggtggtggcggcgatggccggg
cgtacggcggcgcgggtggtgacgttcgggcggcacagcacggcccggatccgcgccgag
cgggtgatgctggacggggccgcgcgggcgcggttcgtgctgcggacccccgccggctcg
gccgaggtcgccctgcgcctgcacggcgagcacttcgtcacggccgcgctggccgccgcc
gcggtggccctggatcacacgcacgacgtgtggctggtcgccgacgcgctgagcgccgcg
acgccgcggtcggaggggcggatgcggctcagcgagcgcccggacggggtgacggtgctc
gacgacgcgtacaacgccaaccccgagtcgatggtcgccgggctgcgggcgctggtcgcc
gtcgccgccgggcgccgccggacggtcgccgtgctcgggcagatgaacgagctgggcgag
gggtcggccaccgcgcacgccgaggtcgggcgggccgccgtacgcctcggggtggacgtc
gtggtggccgtgggcaatcgggacgcggccggctacggcggggtgtacgccccggaccgg
gagacggccgccgccgtgctgcgggggctgatcgagccgggcgacgtcgtgctcgtcaag
gcgtcccacggcctggggctctcggcggtggccgaggccctgatcgacgccgatcagatc
gcgcgcagcgccccgccgtcgaccggcaccgagatgccggtgaggtag
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