Aerococcus sp. Group 1: HMPREF9243_0462
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Entry
HMPREF9243_0462 CDS
T01447
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
aur
Aerococcus sp. Group 1
Pathway
aur00300
Lysine biosynthesis
aur00550
Peptidoglycan biosynthesis
aur01100
Metabolic pathways
aur01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
aur00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HMPREF9243_0462 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HMPREF9243_0462 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HMPREF9243_0462 (murF)
Enzymes [BR:
aur01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HMPREF9243_0462 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
MoCF_biosynth
Motif
Other DBs
NCBI-ProteinID:
AEA00449
UniProt:
F2I7M3
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Position
457456..458844
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AA seq
462 aa
AA seq
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MKALAINEIVKAVGAVDYDSTAAHNLITSVAFNSKEIKPGGLFIPLKAARDGHDFIQDAI
DHGAQATLWANDPADAPSEIPVIQVEDTFTAFVDLAKYYLGLIGPKVIAVTGSAGKTTTK
DMTAATLSTTFNVYKTQGNYNNQLGVPFTILSMPEDTEVLVVEMGMSGPGEIRFLAQLCP
MDVAVITMIGESHIEFLGSRENIAKAKLEILEGLKEDGTFIYPGDEPLVDQAVVDMPEIK
KIRVGLDDSEDVYAENIVNEREHTHFYTNLSPNVELSIPVSGDYNVKNALMACAVAYSQG
LAVEQIKTPLSQFKLTANRSEWLMGKDDIQILNDTYNANPSAMRAVIRNFSQLERPAVTS
HKVLVLGDMLELGKYSASMHASIAEEIDSPHIDGVYLYGKEMQALARALQEKGYPEDKIH
YYPEDKAALIKDLLDQVQSQDQILVKASHGMGLAEVVAALKS
NT seq
1389 nt
NT seq
+upstream
nt +downstream
nt
atgaaagcattagccatcaatgagattgtcaaagccgtgggggcagtagactatgattcc
acagctgcccataacttgattacgtcggtagcctttaattctaaggaaattaagccaggg
ggcttgtttatccccctcaaagctgcccgggatggtcacgattttatccaagatgccatc
gaccatggggcccaagccaccttgtgggctaatgaccccgccgatgcgcctagtgagatc
ccggttatccaggtggaagacaccttcaccgcctttgttgacctggccaaatattattta
ggtctcattggacctaaggtgattgctgttaccggttccgctggcaagaccacgaccaag
gatatgaccgcggccaccctatcaaccaccttcaatgtctataagacccagggcaattat
aataaccaactcggcgttccctttactatcctctccatgccggaagatactgaagtcctg
gtagtcgaaatgggaatgtcaggacctggggaaattcgcttcctggcccaactctgtccc
atggacgttgcggtgattactatgatcggggagagccatattgaattcctcggctcgcga
gaaaatattgccaaggccaagctagaaatcctagaaggcttaaaggaagacggcaccttc
atttacccaggcgacgagcccttggttgaccaagcggtggtcgacatgccggaaatcaaa
aagatccgggtaggactggatgactctgaggatgtctatgccgaaaatattgtcaatgag
cgcgagcatacccatttttataccaacttgtcgcctaatgtggaattatccattcctgtg
agtggcgactataatgtgaagaatgctctgatggcctgtgcggtcgcctatagccaaggc
ttagcggtggaacaaattaaaacgcccctgagtcaatttaagctaacggccaaccgtagt
gagtggttgatgggtaaggatgacatccaaattctcaacgatacctataacgccaacccc
agtgctatgcgggcagttatccgtaatttctcacaattagaacgtcccgctgtcaccagc
cataaggtattggtcttaggggatatgttagaattaggcaagtacagcgccagcatgcat
gccagcattgctgaggagattgatagcccgcatattgacggagtctatctctatggtaaa
gaaatgcaagctttggcgagagccctccaggaaaagggctatcccgaagataaaattcat
tactatcctgaagataaggccgctttaattaaggatttattagaccaagtccaatcacaa
gaccaaatcctggtcaaagccagtcacggtatgggactggctgaagtcgttgctgcgctc
aagtcttaa
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