Castor canadensis (American beaver): 109689795
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Entry
109689795 CDS
T04791
Symbol
Th
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
ccan
Castor canadensis (American beaver)
Pathway
ccan00350
Tyrosine metabolism
ccan00790
Folate biosynthesis
ccan01100
Metabolic pathways
ccan04728
Dopaminergic synapse
ccan04917
Prolactin signaling pathway
ccan05012
Parkinson disease
ccan05030
Cocaine addiction
ccan05031
Amphetamine addiction
ccan05034
Alcoholism
Module
ccan_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
ccan00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
109689795 (Th)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
109689795 (Th)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
109689795 (Th)
09156 Nervous system
04728 Dopaminergic synapse
109689795 (Th)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
109689795 (Th)
09165 Substance dependence
05030 Cocaine addiction
109689795 (Th)
05031 Amphetamine addiction
109689795 (Th)
05034 Alcoholism
109689795 (Th)
Enzymes [BR:
ccan01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
109689795 (Th)
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Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
109689795
NCBI-ProteinID:
XP_020024408
UniProt:
A0A8C0ZZT9
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All DBs
Position
Unknown
AA seq
499 aa
AA seq
DB search
MPTPSAASPQPKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREAAAAAAAAAA
VTSSEPGDPLEAVVFEEKDGKAVLNLLFSLRATKSSLLSRAVKVFETFEAKIHHLETRPA
QRPREGGPHLEYFVRFEVPSGDLAALLSSVRRVSDDVRSAREDKVPWFPRKVSELDKCHH
LVTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYKQGEPIPHVEYTVEEIATWKEVYTT
LKGLYATHACREHLEAFRLLERFCGYREDAIPQLEDVSRFLKERTGFQLRPVAGLLSARD
FLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGV
SDEEIEKLSTVYWFTVEFGLCKQNGELKAYGAGLLSSYGELLHSLSEEPEIRAFDPDTAA
VQPYQDQTYQPVYFVSESFSDAKDKLRSYASRIQRPFSVKFDPYTLAIDVLDSPHAIQHS
LEGVQDELHTLAQALSAMG
NT seq
1500 nt
NT seq
+upstream
nt +downstream
nt
atgcctacccccagtgctgcctcaccacagcccaagggcttcagaagggctgtctcagag
ctggatgccaagcaggctgaggccatcatgtccccacggttcatcggacgaaggcagagc
ctcatcgaggatgctcgaaaggagcgggaggcagcggcggctgcagcagcagcagctgct
gtgacctcctcagagcctggggaccccctggaggctgtggtgtttgaggagaaggatggg
aaagctgtactcaacctgctcttctctctgagggccaccaagtcctccttgctctcacgg
gccgtgaaggtgtttgagacatttgaagccaaaattcaccacctggagacccggccggcc
cagaggcctcgggaggggggtccccacctggagtacttcgtgcgcttcgaggtgcccagc
ggggacctggccgccctgctcagctccgtgcgccgtgtgtcagacgatgtgcgcagtgcc
agggaggacaaggtcccctggttcccaaggaaagtatcagagttggacaaatgtcaccac
ctggtcaccaagtttgaccctgacctggacttggaccatccgggcttctcggaccaggtg
taccgccagcgtcggaagctgatcgctgagattgccttccaatataagcagggtgaaccg
attccccacgtggagtacacagtggaggagattgccacctggaaagaggtctacaccacg
ctgaagggtctgtacgccactcatgcctgccgggagcacctagaggctttccggctattg
gagcgcttctgcggctaccgggaggacgccatcccacagctggaggacgtgtcacgtttc
ctgaaggagcggacaggtttccagctgcggcctgtggccggcctgctgtctgcccgggac
ttcctggccagcctggccttccgcgtgttccagtgcacacagtacatccgccatgcctcc
tcacccatgcactctcctgaaccggactgttgccatgaactgctggggcacgtgcccatg
ctggcagaccggacatttgcccaattctcccaggacattggccttgcatccctgggggtc
tcggatgaggaaattgagaaactgtccacggtgtactggttcactgttgagtttgggctg
tgcaaacaaaatggggagctgaaggcctatggtgcagggctgctgtcttcctacggcgag
ctcctgcactccctgtcagaagagccggagatccgggcctttgaccctgacacagccgct
gtgcagccgtaccaagaccagacctaccagccggtctacttcgtgtctgagagcttcagc
gatgctaaggacaaactcagaagctatgcctcacggatccagcgccccttctctgtgaaa
tttgacccatacacgctagccatcgatgtgctggacagtccccatgctatccagcactcc
ctggagggcgtccaggatgagctgcacaccctggcccaggcgctaagtgccatgggatag
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