Escherichia coli O157 H7 EC4115 (EHEC): ECH74115_0094
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Entry
ECH74115_0094 CDS
T00778
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ecf
Escherichia coli O157:H7 EC4115 (EHEC)
Pathway
ecf00300
Lysine biosynthesis
ecf00550
Peptidoglycan biosynthesis
ecf01100
Metabolic pathways
ecf01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ecf00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ECH74115_0094 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ECH74115_0094 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ECH74115_0094 (murF)
Enzymes [BR:
ecf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ECH74115_0094 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
ACI37612
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Position
99236..100594
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AA seq
452 aa
AA seq
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MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAG
GAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIVWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS
PNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMSVGATL
DAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD
MAELGAESEACHVQVGEAAKAAGIDRVLSVGKQSHAISTASGVGEHFAEKTALITRLKSL
IAEQQVITILVKGSRSAAMEEVVRALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcgtaacccttagccaacttaccgacattctcaacggtgaactgcaaggtgca
gatatcacccttgatgctgtaaccactgatacccgaaaactgacgccgggctgcctgttt
gttgccctgaaaggcgaacgtttcgatgctcatgattttgccgaccaggcgaaagctggc
ggcgcaggcgcactactggttagccgtccgctggatatcgacctgccgcagttaatcgtc
aaggatacgcgtctggcgtttggtgaactggctgcatgggttcgccagcaagttccggcg
cgcgtggttgctctgacaggttcctccggcaaaacctccgttaaagagatgacggcggcg
attttaagccagtgcggcaacacgctttatacggcaggcaatctcaacaacgacatcggt
gtaccgatgacgctgttgcgcttaacgccggaatacgattacgcagttattgaacttggc
gcgaaccatcagggcgaaattgtctggactgtgagtctgactcgcccggaagctgcgctg
gtcaacaacctggcagcggcgcatctggaaggttttggctcgcttgcgggtgtcgcgaaa
gcgaaaggtgaaatctttagcggcctgccggaaaacggtatcgccattatgaacgccgac
aacaacgactggctgaactggcagagcgtaattggctcacgcaaagtgtggcgtttctca
cctaatgccgccaacagcgatttcaccgccaccaatatccatgtgacttcgcacggtacg
gaatttaccctgcaaaccccaaccggtagcgtggatgttctgctgccgttgccggggcgt
cacaatattgcgaatgcgctggcagccgctgcgctctccatgtccgtgggcgcaacgctt
gatgctatcaaagcggggctggcaaatctgaaagctgttccaggccgtttgttccccatt
caactggcagaaaaccagttgctgctcgacgactcctacaacgccaatgtcggttcaatg
accgccgctgttcaggtactggctgaaatgccgggctaccgcgtgctggtggtgggcgat
atggcggaactgggcgctgaaagcgaagcctgccatgtacaggtgggcgaggcggcaaaa
gctgctggtattgaccgcgtgttaagcgtgggtaaacaaagccatgctatcagcaccgcc
agcggcgttggcgaacattttgctgagaaaactgcgttaattacgcgtcttaaatcactg
attgctgagcaacaggtaattacgattttagttaagggttcacgtagtgccgccatggaa
gaggtagtacgcgctttacaggagaatgggacatgttag
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