Escherichia coli SMS-3-5 (environmental): EcSMS35_0091
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Entry
EcSMS35_0091 CDS
T00672
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
ecm
Escherichia coli SMS-3-5 (environmental)
Pathway
ecm00300
Lysine biosynthesis
ecm00550
Peptidoglycan biosynthesis
ecm01100
Metabolic pathways
ecm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
ecm00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
EcSMS35_0091 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
EcSMS35_0091 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
EcSMS35_0091 (murF)
Enzymes [BR:
ecm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
EcSMS35_0091 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
ADH_zinc_N
Motif
Other DBs
NCBI-ProteinID:
ACB18730
UniProt:
B1LG23
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Position
101283..102641
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AA seq
452 aa
AA seq
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MISVTLSQLTDILNGELQGADITLDAVTTDTRKLTPGCLFVALKGERFDAHDFADQAKAG
GAGALLVSRPLDIDLPQLIVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMNADNNDWLNWQSVIGSRKVWRFS
PNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLPLPGRHNIANALAAAALSMAVGATL
DAIKAGLANLKAVPGRLFPIQLVENQLLLDDSYNANVGSMTAAVQVLAEMPGYRVLVVGD
MAELGAESEACHIQVGEAAKAAGIDRVLSVGKQSHAISTASGVGEHFSDKTALIARLKSL
IAEQQVITILVKGSRSAAMEEVVRALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgattagcgtaacccttagccaacttaccgatattctcaacggtgaactgcaaggtgca
gatattacccttgatgctgtaaccactgacacgcgaaaactgacgccgggctgcctgttt
gttgccctgaaaggcgaacgtttcgatgctcatgattttgccgaccaggcgaaagctggc
ggcgcaggcgcactactggttagccgtccgctggatatcgatctgccgcagttaatcgtc
aaggatacgcgtctggcgtttggtgaactggctgcatgggttcgccagcaagttccggcg
cgcgtggttgctctgacaggttcctccggcaaaacatccgttaaagagatgacggcggcg
attttaagccagtgcggcaacacgctttatacggcaggcaatctcaacaacgacatcggc
gtaccgatgacgctgttgcgcttaacgccggaatacgattacgcagttattgaacttggc
gcgaaccatcagggcgaaattgcctggactgtgagtctgactcgcccggaagcggcgctg
gtcaacaacctggcagcggcacatctggaaggttttggctcgcttgcgggtgtcgcgaaa
gcgaaaggtgaaatctttagcggcctgccggaaaacggtatcgccatcatgaacgctgac
aacaacgactggctgaactggcagagcgtaattggctcacgcaaagtgtggcgtttctca
cccaatgccgccaacagcgatttcaccgccaccaatatccatgtgacttcgcacggtacg
gaatttaccctgcaaaccccaaccggtagcgtggatgttctgctgccgttgccggggcgt
cacaatattgcgaatgcgctggcagccgctgcgctctccatggccgtgggcgcaacgctt
gatgctatcaaagcggggctggcaaatctgaaagctgttccaggccgtctgttccccatt
caactggtagaaaaccagttgctgctcgacgactcctacaacgccaatgttggttcaatg
actgcagcagtccaggtactggctgaaatgccgggctaccgcgtgctggtggtgggcgat
atggcggaactgggcgctgaaagcgaagcctgccatatacaggtgggcgaagcggcaaaa
gcagctggtattgaccgcgtgttaagcgtgggcaaacaaagccatgctatcagcaccgcc
agcggcgttggcgaacatttttccgataaaactgcgcttatcgcgcgtcttaaatcactg
attgctgagcaacaggtaattacgattttagttaagggttcacgtagtgctgccatggaa
gaggtagtacgcgctttacaggagaatgggacatgttag
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