Enterobacter cloacae subsp. cloacae ATCC 13047: ECL_00883
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Entry
ECL_00883 CDS
T01231
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
enc
Enterobacter cloacae subsp. cloacae ATCC 13047
Pathway
enc00300
Lysine biosynthesis
enc00550
Peptidoglycan biosynthesis
enc01100
Metabolic pathways
enc01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
enc00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ECL_00883
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ECL_00883
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ECL_00883
Enzymes [BR:
enc01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ECL_00883
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LpxD
Motif
Other DBs
NCBI-ProteinID:
ADF60446
UniProt:
A0A0H3CH14
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Position
883844..885202
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AA seq
452 aa
AA seq
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MISLTLGKAATLLQGTLHGQDLTIDAVTTDTRKVTAGCLFVALKGERFDAHDFAEQAKEN
GAGALLVNRKLDIDLPQIVVKDTRLAFGELAAWVRQQVPARVVALTGSSGKTSVKEMTAA
ILSQCGNTLYTAGNLNNDIGVPMTLLRLTKEHDFAVIELGANHQGEIAWTVSLTRPEAAL
VNNLAAAHLEGFGSLEGVAKAKGEIYTGLPDNGIAIMNADNNDWLNWQSIIGSRKTWRFS
PNAADSDFTATHIHVTSHGTEFTLNTPTGGIEVLLPLPGRHNIANALAAAALSMAVGATH
DAIKTGLANLKAVPGRLFPVQLAENKLLLDDSYNANVGSMTAAVQVLSEMPGYRVMVVGD
MAELGDESEACHIQVGEAAKAAGLDCVLSAGKLSQAISHASGVGEHFADKAALIERLKTL
IAEKQIVTVLVKGSRSAAMEEVVHALQENGTC
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgatcagcttaacgctcggcaaggcggcaaccctcctgcaggggacgttacatggtcag
gatctgaccatcgacgccgtgacgacagatacccgcaaagtgaccgccgggtgcctgttt
gtggcgctgaagggcgaacgttttgacgcccacgattttgctgaacaggcgaaagagaat
ggtgcgggtgcgctgctagtgaaccgcaaactcgatatcgatttaccgcagattgtggtg
aaggatacgcgccttgccttcggtgagctggcagcatgggttcgtcagcaggtgccagct
cgcgttgttgctctgacggggtcttcgggcaaaacgtcagtaaaagagatgacggcggcg
atcctcagtcagtgcggtaacacgctttacaccgcaggcaatctaaataatgacatcggc
gtgccgatgacattgcttcgcctcaccaaagagcatgactttgcggtgattgaattaggg
gcaaaccaccagggtgaaattgcctggacggtcagcctgacgcgtccggaggctgcgctg
gtgaacaacctggccgccgcgcatctggaaggtttcggttcacttgaaggcgtggcgaaa
gccaaaggtgagatctataccggcctgccggataacggtatcgccattatgaatgccgat
aataacgactggttgaactggcagagcatcatcggttcacgtaagacgtggcgcttctcg
cctaatgcggcagacagtgattttaccgcgacccatatccatgtgacctcgcatggtacg
gaattcacgctcaataccccaacgggaggcattgaggttctgctgccgctgccgggtcgc
cataacatcgccaatgcgcttgctgccgcggcgctgtcgatggccgtcggcgcgacacat
gacgcgatcaagactggccttgcgaatttaaaagccgtaccgggacgtctgttcccagtc
cagcttgcagaaaacaaactgctgctggatgactcctacaacgcgaacgtcggttcgatg
acggcagccgtacaggtgttgtccgaaatgccaggctatcgcgtgatggtggttggcgat
atggccgagttgggcgatgagagcgaagcctgtcatatccaggtgggtgaagccgcgaaa
gcggccgggctggattgcgtactgagcgcaggaaaactgagccaggcgattagccatgcc
agcggtgttggcgaacattttgccgataaagccgcactgattgaacgtctgaagacgttg
attgctgaaaaacaaattgtgactgtgttagtgaaaggttcacgtagtgccgccatggaa
gaggtagtgcacgcattacaggagaacgggacatgttag
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