Hydrogenobaculum sp. HO: HydHO_1345
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Entry
HydHO_1345 CDS
T02482
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
hho
Hydrogenobaculum sp. HO
Pathway
hho00300
Lysine biosynthesis
hho00550
Peptidoglycan biosynthesis
hho01100
Metabolic pathways
hho01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
hho00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
HydHO_1345
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
HydHO_1345
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
HydHO_1345
Enzymes [BR:
hho01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
HydHO_1345
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF3726
Motif
Other DBs
NCBI-ProteinID:
AGG15656
UniProt:
M1REU6
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Position
1266526..1267866
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AA seq
446 aa
AA seq
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MNSLEVSKSLGLIHEGKPFLIKDVFFDSREPVKDALFVAIKGEKTDGHLYIKNLLNENIA
GFLVREDFDCKEILAKGKSCLKAKDTIKALQDIASLKRISLKANVVAIAGSAGKTTTKEL
IAHVLPGKVHKTYKNFNSQIGLPKVVITADNDIDYLVLEMGATALEDVKKLTNIAKQHVG
VISSIGEEHLESFGSIENVVKGNFEVFDSPNLLSGVYPKAFHSFYKKEYGLSFCRFRDDA
DIRVKNVYIDEEGTHFEIMGIRLTIPVLSIGIAESAAAAVGVLASFGIDWKELKDRFESF
KGVQGRMQLIKKGPFRIIDDTYNANPVSVRNAILTIDSFKDFNKIIVLGDMLEMGEYSKA
LHEKVGAMLKSSHINNVYLYGSDMKYAYDVLKLSNKEVFYFDNQEELSFHLVKSLKQKTD
TNTMILVKGSRGMKMENVVDRLVNGL
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
atgaactctttagaagtttctaaaagcttaggtttgatacacgagggaaaaccttttttg
ataaaagatgtattttttgattcaagggagcctgtaaaagatgctttgtttgtagctata
aaaggagaaaaaaccgatggacatctttatataaaaaaccttcttaatgaaaatatagca
gggtttttggtaagagaagattttgactgtaaagagatactagcaaaaggtaaatcttgt
ctaaaagccaaagatacgataaaggctttgcaggatatagcctctttgaaaaggattagt
cttaaagcaaatgttgtagcgatagctggttctgctggtaagaccactacaaaagagctt
atagctcatgtattacctggtaaagtgcataaaacttacaaaaattttaactctcaaata
gggcttccaaaggtagttataacagctgataatgatatagattatcttgtgttggagatg
ggagctaccgcattagaagatgtaaaaaagcttacaaatattgcaaaacaacatgttggg
gttatatcttctataggagaagagcaccttgagagttttggctctattgaaaacgtggta
aaaggaaactttgaagtgtttgactctccgaatcttttgtctggggtctatcctaaggcg
tttcatagcttttataaaaaagaatatgggcttagtttttgtagatttagagatgatgct
gatataagagtaaaaaatgtctatatagacgaagaaggtacacattttgagataatggga
atcaggcttactataccagtgcttagcataggtatagcagagagtgcggcagcagcggtt
ggtgttcttgcatcttttggtatagattggaaggagttaaaagataggtttgagagtttt
aaaggtgtgcaaggaaggatgcaacttataaaaaaaggaccttttagaataatagacgat
acttacaacgcaaatcctgtttctgtaagaaatgccattcttactatagatagttttaaa
gattttaataagataatagttttgggagatatgcttgagatgggagagtattcaaaggct
cttcacgagaaggtaggggctatgctgaagtcttctcatattaacaatgtgtatctttat
ggaagcgatatgaaatacgcttacgatgttttaaaactttccaacaaagaagttttttac
tttgataatcaagaggagctgtcttttcatcttgttaaaagcctaaaacaaaaaaccgat
accaatacaatgattttggtaaaaggctctagaggcatgaagatggaaaacgttgtggat
aggcttgtaaatggtttataa
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