Hyaena hyaena (striped hyena): 120243477
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Entry
120243477 CDS
T07257
Symbol
KMT2B
Name
(RefSeq) histone-lysine N-methyltransferase 2B
KO
K14959
[histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:
2.1.1.354
]
Organism
hhv
Hyaena hyaena (striped hyena)
Pathway
hhv00310
Lysine degradation
hhv01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
hhv00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
120243477 (KMT2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
hhv03000
]
120243477 (KMT2B)
03036 Chromosome and associated proteins [BR:
hhv03036
]
120243477 (KMT2B)
Enzymes [BR:
hhv01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.354 [histone H3]-lysine4 N-trimethyltransferase
120243477 (KMT2B)
Transcription factors [BR:
hhv03000
]
Eukaryotic type
Zinc finger
CXXC CpG-binding proteins
120243477 (KMT2B)
Chromosome and associated proteins [BR:
hhv03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
120243477 (KMT2B)
HMT complexes
MLL3/MLL4 complex
120243477 (KMT2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SET
FYRC
FYRN
PHD
zf-CXXC
zf-HC5HC2H
zf-HC5HC2H_2
Bromodomain
Motif
Other DBs
NCBI-GeneID:
120243477
NCBI-ProteinID:
XP_039105551
LinkDB
All DBs
Position
Unknown
AA seq
2715 aa
AA seq
DB search
MAAAAGGGSCPGPGSARGRFPGRPRGSGGGGGRGGRGSGAERVRVALRRGGGAAGPGGAE
PGEDTALLRLLGLRRGLRRLRRLWAGPRVQRGRGRGRGRGWGPSRGSVPEESSDEESDDE
EFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPIPPPRLADVAPTPPKTPARKR
GEEGTERMVQALTELLRRAQAPPAPRGRACEPSTPRRSRGRPPGRPAGPCRKKQQAVVVA
EAAVTIPKPEPPPPVVPVKHRTGSWKCKEGPGPGPGTPKRGGQSGRGGRGGRGRGRGGLP
LVIKFVSKAKKVKMGQLSLGLESGQGQDQHEESWQDAPQGRVGSGQGEGPCWRKEQKLEE
EGEKETEEEKGKEEGEEKVERAAPEEEMMLAEEKEEAKLPSPPSTPPAPAAPPPPPPPPP
SPLPPPPPSPPPPPPVSPLPPPSPPPPPVPEEQEESPPPVVPATCSRKRGRPPLTPSQRA
EREAARAVPEGTPPTPTPSTTTGGPLEESPTVAPKSTTFLKNIRQFIMPVVSARSSRVIK
TPRRFMDEDPPKPLKVEVSPTLRPPVATSPLAPPEPAPAPSPPRAPTPPSTPVPLPEKRR
SILREPTFRWTSLTRELPPPPPAPPPAPPPLPAPVTPSRRPLLLRAPQFTPSEAHLKIYE
SVLTTPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVATPVKAEVPLPGA
PPLSNGQQPQAQLQQPLQALQTQLLPQALPPQQPQLQLQPQPPPQQPPPLEKARIAGLGS
LPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVASLMPPSPGGQMEEVVGTVKQLSDRGSV
RSEDESMETKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSALPLRDRQ
DLATEDTSSASETESVPSRSRRGKAESAGPGGDSEPAGSGGTLAQTPRRSLPSHHGKKMR
MARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERLAKKGRT
IVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAPPGPEEQDSLLLQRKSARRCVK
QRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPVPEPEEQSRPRKPTLQPVLQLKARRRL
DKDALAPGPFTSFPNGWTGKQKSPDGVHRVRVDFKEDCDLENVWLMGGLSVLTSVPGGPP
MVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVCGRKGRG
SKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGATPGKNWDVEWSGD
YSLCPRCTQLYEKGNFCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDEDYEILSG
LPDSVLYTCGPCAGATHPRWREALSGALQGGLRQVLQGLLSSKVAGPLLLCTQCGQAGKQ
LHPGPCDLQAVSRRFEEGHYKSVHSFMEDMVAILMRHSEEGETPERRAGGQMKGLLLKLL
ESAFGWFDAHDPKYWRRSTRLPNGVLPNAVLPPSLDHVYAQWRQQEPETPESGQPPGDPS
AAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWSAEVFEE
NDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQDDKKVF
CQKHTDLLDGKEIVTPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSIRIDSLG
TLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPVHLEAAEEN
QTIVHSPAPSSETPDHVDPPPDTDALIPGAPEHHSPVQNLDPPHRPDLSSAPPSAPRSFS
GARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDLDFPAPPRRSRRPSPLAP
RLPPSRRASPPLRTSPQLRVPPPTSVVRALTPTSGELAPPGPAPSPPPPPEDLGPDFEDM
EVVSGLSAADLDFAASLLGTEPFQEEIVAAGAVGSSHGGPGDSSEEEASPSPRYVHFPVT
VVSGPALAPGALPGPPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVGRAGVIGAAG
DRSRPPEDLPSEIVDFVLKNLGGPGEGGAGPREEPLPPAPPLANGSQPSQGLPPSPADPT
RTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVSPPVKQPPL
PPPIPSTAPASWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPPSPPHQAIRVKR
VSTFSGRSPPAPPPNKTPRLEEDGESLEDAPQGPGLSGSGFSRVRMKTPTVRGVLDLDEP
GEPTGEESPRPFQDRSPLLPLPEGGPPRAPDGPPDLLLESQWHHYSGEASSSEEEPPSPE
DKENQAPKRAGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEARGHARLRHLSFSGMS
GARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQEEPPLNPHGAARAEVYLRKCT
FDMFNFLASQHRVLPEGATCEEEEDEVQLRSTRRATSLELPMAMRFRHLKKTSKEAVGVY
RSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMDDFDVVD
ATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPIEDASNK
LPCNCGAKRCRRFLN
NT seq
8148 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggcggcgggcggcggcagttgccccgggcctggctccgcgcggggccgcttc
ccgggccggccgcggggctccggcgggggcgggggccgcggcggacggggcagcggggcc
gagagagtgcgggtagcgctgcggcgcggcggcggcgcggcggggccgggcggagccgag
cctggggaggacacggccctgctccgtttgctggggctccgccggggcctgcgccggctc
cgccgactgtgggccggcccgcgcgttcagcggggccgaggccggggccggggccggggc
tggggccccagccggggcagcgtgcctgaggagagcagtgacgaggaatccgacgatgag
gagtttcagggttttcattcagatgaagatgtggcccccagttccctgcgctctgcgctc
cgatcccagcgaggtcgagccccccgaggtcggggccgcaagcataagacgacccccatt
ccgcctcctcgcctagcagatgttgctcctacccccccaaagactcctgcccggaaacgg
ggtgaggaaggcacagaacggatggtacaggcactgactgaacttctccggcgggcccag
gcacccccagccccccggggccgggcatgtgagccttccactccgcgtcggtctcgggga
cggcccccaggacggccagcaggcccctgcaggaagaagcaacaagcagtagtggtggca
gaagcagctgtgacaatccccaaacctgagcccccacctcctgtggttccagtaaaacac
cgaactggcagctggaagtgcaaggaagggcccggcccaggacctgggacccctaagcgt
ggaggacagtctgggcgaggaggccgtggaggtagaggccgaggccgaggcgggctccct
ctcgtgatcaagtttgtttcaaaggccaaaaaagtgaagatgggacagttgtccttggga
cttgaatcaggtcagggtcaagatcaacatgaggaaagctggcaggatgccccccaagga
agagttggatctgggcagggagagggcccctgctggaggaaagagcaaaagctggaggag
gagggagagaaggagacagaagaggagaaaggcaaggaggagggggaagagaaggtagaa
agagctgcacctgaagaagagatgatgctagcggaggaaaaggaagaggcaaagctgccg
tccccaccctcgacgcctccagcccctgcagcccctccaccccctccaccccctccaccc
tctcccctccctccaccccctccatctcctcctccaccaccgccagtgtctcctctgccc
ccaccatcgcctccaccgcctcctgtcccagaggagcaggaagaatcccctcctccagtg
gttccagctacatgctccaggaagaggggccggcctcccctgactcccagccagcgggca
gagcgagaagctgctcgggcagtgccagaaggtactcctcccactccaacccccagcacc
accacgggaggccctctggaagaaagccccactgtggcccccaaaagtaccaccttcctg
aagaacatccggcagtttattatgcccgtggtgagtgcccgctcctcccgtgtcatcaag
acacctcggcgatttatggatgaagacccccccaagcccctaaaggtagaagtctcacct
actctgcggcctcctgttgccacctccccactcgcccccccggaaccggcaccagctccc
tctccaccacgtgccccaactcccccctctaccccagtcccgcttcctgaaaagagacgg
tccattctaagggaacccacgtttcgctggacctcactgacccgggaactgcccccgccg
cctcctgctcctccaccggccccacccccacttcctgcccctgtcactccatcccggagg
cccctgctccttcgggcgcctcagtttaccccaagtgaagcccacctgaagatctacgaa
tcggtgcttactactcctcttggggcccctgaagcacctgagccagagccgcctcctgcc
gatgactctccagctgagcctgagccacgggcagtgggccgcaccaaccacctcagcctg
cctcgatttgcccctgtggtcgccactcctgttaaggccgaggtgccccttcctggggcg
ccacctctgagcaatgggcagcagcctcaggctcagctacagcagcccctacaggccttg
caaacccagttgctgccccaggcattaccaccacagcagccacagttacaactgcagcca
cagccaccaccacagcagccgccaccactggaaaaggcccgtattgcaggcttgggttcc
ttaccactgtctggtgtggaggagaaaatgttcagcctcctcaagagagccaaggtgcag
ctgttcaagatcgatcagcagcagcagcagaaggtggcgtctttgatgccgccgagccct
ggagggcagatggaggaagtcgtgggtactgtcaagcaactctcagatagaggttctgtc
aggtctgaagatgaatcgatggaaactaagagagagagaccgtcgggccctgagtcccct
gtgcaaggcccccgcatcaaacacgtctgtcgtcatgctgctgtggccctaggtcaggcc
cgggctatggtgcccgaagacgtcccccgcctcagtgctcttcctctccgggatcggcag
gacctcgccacggaggatacatcgtcagcatctgagactgagagtgtcccatcgcggtct
cggcggggaaaggcggagtcagcgggccctgggggagactcagagcctgcagggtctgga
gggaccctggcccaaacgccccggcgctctctgccctcccatcatggcaagaagatgcgg
atggcacggtgtggacactgtcggggctgcctgcgtgtgcaggactgtgggtcctgtgtc
aactgcctggacaagcccaagtttgggggccccaacaccaagaagcagtgctgtgtatac
cggaagtgtgacaagatagaggctcggaagatggaacgattggctaaaaaaggccggacg
atagtgaagacgctgttgccctgggattccgatgaatctcctgaggcctcccctggtcct
ccaggcccacgccggggggcgggagctggggggccccgggaggaggtggtggccccccca
gggcccgaggagcaggactccctcctactgcagcgcaagtcagcccggcgctgcgtcaaa
cagcgaccctcctatgatatcttcgaggactcggatgactcagagcctgggggtccccct
gctccccggcgtcggaccccccgagagaatgagctaccagtgccagaacctgaggagcag
agccggccccgcaaacccaccctgcagcctgtgttgcagcttaaggcccgaaggcgcctg
gacaaggatgctctggctcctggcccctttacttcttttcccaatggttggactggaaag
cagaagtcccctgatggagtacaccgggtccgtgtggattttaaggaggattgtgacctg
gagaacgtgtggctgatgggcggcctcagcgtgctcacgtccgtgccaggggggccgccg
atggtgtgcttactgtgtgccagtaaaggcctgcatgagctggtgttctgccaagtgtgc
tgtgaccctttccatccattctgtctggaggaggccgaacggcccctgccccaacatcat
gacacctggtgctgccgccgctgcaagttttgccacgtctgtggacgcaaaggccgggga
tccaagcacctcctagagtgtgagcgctgccgccatgcttatcacccagcctgcctgggg
cccagctacccaacccgggccacacgcaaacggcgtcactggatctgctcagcctgcgta
cgctgtaagagctgtggggcgactccaggcaagaactgggacgtcgagtggtctggagat
tacagcctctgccccaggtgcacccagctctatgagaaaggaaatttctgcccaatctgc
acacgctgctatgaagacaacgactatgagagcaagatgatgcagtgcgcacagtgtgac
cactgggtgcatgccaagtgcgagggactctcggatgaagactacgagatcctttctggg
ctgccagactctgtgctgtatacctgcggaccatgtgcaggagccacacacccccgctgg
cgagaggccctgagtggggccctgcaggggggcctacgccaggtgctccagggcctactg
agctccaaagtggcgggcccactgctgctgtgcactcagtgtgggcaggctggaaagcag
ctgcacccagggccctgtgatctgcaagccgtgagtcggcgctttgaggaaggccactac
aagtccgtgcacagctttatggaggacatggtggccatcctgatgaggcactcggaagaa
ggagagaccccagagcgccgggctggaggccagatgaaggggctcctactgaagctgcta
gagtctgcgttcggctggttcgacgcccatgaccccaagtactggcgacggagtacccgg
ctgccaaacggagttcttcccaatgccgtgttgcccccgtccttggaccatgtctacgct
cagtggaggcagcaggagccagagaccccagaatcagggcagcctccaggggacccctca
gcagcttttcagggcaaggatccagctgctttctcacacctggaggacccccgtcagtgt
gcactctgcctcaaatatggtgatgcggactctaaggaggcaggacggctcctatacatt
gggcagaatgaatggacacatgtcaactgtgccatttggtcagctgaagtgtttgaggaa
aatgatggctccctcaaaaacgtgcatgctgctgtagctcgagggaggcagatgcgctgt
gagctctgcctgaagcctggagccacggtgggctgctgcctttcctcctgcctcagcaac
ttccacttcatgtgtgcccgggccagctattgcatcttccaggacgacaagaaagttttc
tgccagaaacacacagacctgctggatggcaaagagattgtgacccctgatgggtttgac
gttctccgccgagtctatgtggactttgagggcatcaactttaagcgaaagttcttgacg
gggctcgaacctgatgccatcaatgtgctcattggttccatccgaattgactccttgggt
accctgtctgatctctcagactgcgagggacggctcttccccattggctaccagtgctcc
cgtctgtactggagcacagtggatgctcggcggcgctgctggtatcggtgtcgtattctg
gagtatcggccgtggggtccgagggaagagccagttcacctggaggcagcagaggagaac
cagaccattgtgcacagccctgccccttcctcagaaaccccagatcatgtggacccccca
ccagatacagatgcccttatccctggagctcctgagcaccactcacctgttcagaacctg
gaccccccacatcggccagatctaagcagtgcccctccttcagccccccgctccttctca
ggggctcgaatcaaagtgcccaactactcaccatcccggaggcccttggggggtgtctcc
tttggacccctgccctcccctggaagtccatcttctctgacccaccacatccccacggtg
ggagacctggactttccagctccccccagacgctctcgtcgtcccagccccctggcccca
aggctgccaccatcacggcgggcctctccccctctcagaacctccccacagctcagggtg
ccccctcctacctcagtcgttagagccctcacacctacctcaggggagctggctccccct
ggcccagccccatctcctccacccccccccgaagacctgggcccagactttgaggacatg
gaggtggtgtcaggactgagtgctgctgacctggactttgcggccagcctgctggggact
gagcccttccaggaagagattgtggctgcaggggcagtggggagcagccatgggggtcca
ggggacagctcagaggaggaggctagcccttccccccgctatgtccacttccctgtgact
gtggtgtctggccctgccctggcccctggtgccctccctggacccccccgcatcgaacag
ctggatggagtggatgacggcacagacagcgaggcagaggcagtccagcagcctcggggc
caggggacgcctccttcagggccaggagtaggccgggctggggtcatcggggctgcaggg
gacagaagccgacctcctgaggacttgccatcagaaattgtggattttgtgttgaagaac
ctaggagggcctggggagggaggtgctgggcccagagaggagccactccccccagcacct
cccctggccaatggcagccagccttcccagggcctaccccctagcccagctgaccccact
cggacgtttgcctggctccctggggctccaggggtccgggtgttgagcctgggccctgcc
cctgagccccccaaacccgccacatccaaaatcatccttgtcaacaagctcgggcaagtg
tttgtgaagatggctggggagggtgaacctgtctcacccccagtgaagcagccacctcta
ccccctcccatcccttctacagcccctgcttcctggactctgcccccaggaccgctgctg
ggtgtgttgccagtggtaggggtggtccgccccgccccacccccacccccccctccactg
accttggtgttgagcagtggaccccccagcccaccccatcaggccatccgcgtcaagagg
gtgtccaccttctctggccgttccccaccagcgcctcccccaaacaagactccccggctg
gaggaagatggagagtccttggaggatgctccccaaggtccagggcttagtggcagcggg
tttagccgagtaaggatgaaaacgcccacagtgcgtggcgttcttgacttggatgagcct
ggagagcccacaggggaggaaagcccaaggcccttccaggaccggtcccctctgctgcca
ctcccagaaggtggtcctcctcgggcccctgatggtccccctgacctgctgcttgagtcc
cagtggcaccactactcaggtgaggcttcgagctccgaggaagagcctccatccccagaa
gacaaagagaaccaggcccccaaacgggctggcccacatctgcgctttgagatcagcagt
gaggatgggttcagcgtggaggcagagagcttggagggggcgtggagaactctgattgag
aaggtgcaagaggcccgagggcacgcccgcctccgacatctctccttcagcggaatgagt
ggggcaaggctcctgggcatccaccacgatgctgtcatcttcctggcagagcagctgccc
ggagcccagcgctgccagcactataagttccgctaccaccagcagggagagggccaggag
gaaccacccctaaatccccacggggcagcccgtgccgaggtctatctccggaagtgcacc
tttgacatgttcaacttcctggcctcccagcaccgggtgctccctgagggagccacctgt
gaagaggaagaggatgaggtgcagctcaggtcaaccagacgtgccaccagcctggagctg
cccatggccatgcgctttcgccacctcaagaagacatccaaagaggctgtgggtgtctac
agatctgccatccatgggcggggcctattctgtaagcgaaacatcgatgccggcgagatg
gtcattgagtattctggtattgtcattcgctctgtgctgactgacaagcgggagaagttc
tacgatgggaagggtattgggtgctacatgttccgcatggatgactttgatgtggtggat
gccacaatgcatggcaacgctgcccgcttcatcaaccactcgtgtgagcccaactgcttc
tctcgggtcatccacgtggagggccagaagcacatcgtcatcttcgccctgcgccgcatc
ctgcgtggtgaggagctcacctatgactacaaattccccatcgaggatgccagcaacaag
ctgccctgcaactgtggcgccaagcgctgccgccggttccttaactga
DBGET
integrated database retrieval system
