Mus caroli (Ryukyu mouse): 110298803
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Entry
110298803 CDS
T05910
Symbol
Th
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
mcal
Mus caroli (Ryukyu mouse)
Pathway
mcal00350
Tyrosine metabolism
mcal00790
Folate biosynthesis
mcal01100
Metabolic pathways
mcal04728
Dopaminergic synapse
mcal04917
Prolactin signaling pathway
mcal05012
Parkinson disease
mcal05030
Cocaine addiction
mcal05031
Amphetamine addiction
mcal05034
Alcoholism
Module
mcal_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
mcal00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
110298803 (Th)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
110298803 (Th)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
110298803 (Th)
09156 Nervous system
04728 Dopaminergic synapse
110298803 (Th)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
110298803 (Th)
09165 Substance dependence
05030 Cocaine addiction
110298803 (Th)
05031 Amphetamine addiction
110298803 (Th)
05034 Alcoholism
110298803 (Th)
Enzymes [BR:
mcal01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
110298803 (Th)
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Gene cluster
GFIT
Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
110298803
NCBI-ProteinID:
XP_021023933
Ensembl:
MGP_CAROLIEiJ_G0030731
UniProt:
A0A6P5Q3G1
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All DBs
Position
7:complement(145085767..145122318)
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AA seq
498 aa
AA seq
DB search
MPTPSASSPQPKGFRRAVSEQDTKQAEAVTSPRFIGRRQSLIEDARKEREAAAAAAAAAV
ASTEPGNPLEAVVFEERDGNAVLNLLFSLRGTKPSSLSRAVKVFETFEAKIHHLETRPAQ
RPLAGSPHLEYFVRFEVPSGDLAALLSSVRRVSDDVRSAREDKVPWFPRKVSELDKCHHL
VTKFDPDLDLDHPGFSDQVYRQRRKLIAEIAFQYKQGEPIPHVEYTKEEIATWKEVYTTL
KGLYATHACREHLEAFQLLERYCGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDF
LASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGAS
DEEIEKLSTVYWFTVEFGLCKQNGELKAYGAGLLSSYGELLHSLSEEPEVRAFDPDTAAV
QPYQDQTYQPVYFVSESFSDAKDKLRNYASRIQRPFSVKFDPYTLAIDVLDSPHTIRRSL
EGVQDELHTLTQALSAIS
NT seq
1497 nt
NT seq
+upstream
nt +downstream
nt
atgcccacccccagcgcctcctcgccacagcccaagggcttcagaagagccgtctcagag
caggataccaagcaggctgaggctgtcacgtccccaaggttcattggacggcggcagagt
ctcatcgaggatgcccgcaaggagcgggaggcggcagcagctgcagcagcggctgcggta
gcctccacggaacctgggaacccgttggaggctgtggtattcgaggagagggatggaaat
gctgttctcaacctgctcttctccttgaggggtacaaaaccctcctcactgtctcgagct
gtgaaagtgtttgagacatttgaagccaaaatccaccacttagagacccggcctgcccag
aggccactggcgggaagcccccacctggagtactttgtgcgctttgaggtgcccagtggc
gatctggctgccctcctcagttctgtgcgtcgggtgtctgacgatgtgcgcagtgccaga
gaggacaaggttccctggttcccaaggaaagtgtcagagttggataagtgtcaccacctg
gtcaccaagtttgaccctgacctggacctggaccatccgggcttctctgaccaggtgtat
cgccagcgccggaagctgattgcagagattgccttccaatacaagcagggtgaaccaatt
ccccacgtggaatacacaaaggaggaaattgctacctggaaggaggtatacaccacgctg
aagggcctctatgctacccacgcctgccgggagcacctggaggctttccagcttctggaa
cggtattgtggctaccgagaggacagcattccacagctggaggatgtgtcccgcttcttg
aaggagaggactggcttccagctgcgacctgtggccggtctactgtctgcccgtgatttt
ctggccagtctggccttccgtgtgtttcaatgcacacagtacatccgtcatgcctcctca
cctatgcattcacctgagccagactgctgccacgagctgctgggacacgtacccatgttg
gctgaccgcacatttgcccagttctcccaggacattggacttgcatctctgggggcttca
gatgaagaaattgagaaactctccacggtgtactggttcactgtggagtttgggctgtgt
aaacagaacggggagctgaaggcttacggtgcggggctgctgtcttcctatggagagctc
ctgcactccctgtcagaggagcccgaggtccgggcctttgacccagacacagcggccgtg
cagccctaccaagatcaaacctaccagccggtgtactttgtgtcagagagcttcagtgat
gccaaggacaagctcaggaactatgcctctcgtatccagcgcccattctccgtgaagttt
gacccgtacaccctggccattgatgtactggacagtcctcacaccatccggcgctccttg
gagggggtccaggatgagctgcacaccctgacccaagcactgagtgccattagctaa
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