Methylovorus glucosetrophus: Msip34_0456
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Entry
Msip34_0456 CDS
T00943
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
mei
Methylovorus glucosetrophus
Pathway
mei00300
Lysine biosynthesis
mei00550
Peptidoglycan biosynthesis
mei01100
Metabolic pathways
mei01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
mei00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Msip34_0456
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Msip34_0456
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Msip34_0456
Enzymes [BR:
mei01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Msip34_0456
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
ACT49704
UniProt:
C6X984
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Position
476413..477786
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AA seq
457 aa
AA seq
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MMRLSELAAAVGGELVGEDVLFTSVGTDSRNIVPGQLFIALRGERFDGHAYVLQALQSGA
AAALVAEAQPGMAAGVVVKNTRLALGQLAAVWRNRFSIPVAAITGSNGKTTVKEMVASIL
RAEAGDSNAVLATRGNLNNDIGLPLTLLRLRPSHKYTVAEMGMNHFGEIRYLSQMARPTV
ALVNNATSAHLGGLGSVEGIARAKGEIFEGLALEGMAVINADDLYAPLWTELAGEHDILT
FGLAKMADVTANYELRADTSYVYMKSPIGGIAFNLQVAGLHNVRNALAASTVAIAMGARP
ESIAKGLEAFDGVDGRLQHRAGIGQALVIDDTYNANPASMRAAIDVLAARPGKRLLVLGD
MGELGETAAAMHTEIGQYAREAGINGLYTLGDLSLEMSKAFGDPAHHYKTPEQLVAGLCH
EMDANTVVLVKGSRFMRMERVVQLIVSEQNNTKEEAH
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atgatgcgtttgtccgagttggcggctgcagtaggcggcgagctggtgggggaggatgtg
ctgttcaccagcgtgggcaccgatagccgcaatatcgtgccaggtcagctgtttattgcc
ctgcgtggcgaacggtttgatggtcacgcctatgtgctgcaggcactgcagtccggtgcc
gcggctgcgttggtggcagaggcccagccaggcatggctgctggtgtggtggtcaaaaat
acgcgcctggcattgggtcaactggccgccgtgtggcgcaaccgtttctcaattccggtg
gcagcgattaccggtagcaacggcaaaaccacggtcaaggaaatggtcgcttccattctg
cgtgccgaggccggtgacagcaatgccgtgctggcgacacgtggcaatctcaataacgac
attggcctgccgctgacgttgctgcgcttgcgtccctcgcacaaatacaccgtggccgag
atgggcatgaaccattttggtgaaatccgctacctgagccagatggcgcgacctaccgtg
gcgctggtcaacaatgccaccagtgcccacctgggcgggcttggctccgtagaaggcatc
gcccgcgccaagggtgaaatctttgaagggctggcgttggaaggcatggccgtcatcaat
gccgatgatctttacgcgccgctgtggaccgagctcgcaggcgaacatgacattctgacc
tttggcctcgccaagatggccgatgttacagccaattatgagctgcgtgctgataccagt
tatgtctacatgaaatcgcccataggcggcattgccttcaacctgcaagtggcaggtttg
cacaatgtgcgcaatgccctggctgccagcacggtggccattgccatgggcgcaagacca
gagtcgatagccaagggcctggaagcctttgatggtgtggatggccgcctgcagcatcgc
gctggtatcggtcaggcactggtaattgatgacacctataacgccaacccggcctccatg
agagctgcgattgatgtgcttgccgcccgcccgggcaagcgcctgctggtgctgggcgac
atgggcgagctgggagaaactgccgctgccatgcataccgaaatcggccaatacgcccgt
gaggctggcattaatggtctctacacgctgggcgatttgtctctggaaatgagcaaagcc
ttcggtgaccctgcccatcattacaaaacgcctgagcagctggtggctggcctctgccat
gagatggatgccaataccgtggtgctggtgaaaggctcacgcttcatgcgcatggagcgc
gtcgtgcagttgattgtgagtgaacaaaataatacgaaagaggaggcgcactaa
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