Methylibium sp. Pch-M: C1M51_11435
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Entry
C1M51_11435 CDS
T05827
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
metp
Methylibium sp. Pch-M
Pathway
metp00300
Lysine biosynthesis
metp00550
Peptidoglycan biosynthesis
metp01100
Metabolic pathways
metp01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
metp00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
C1M51_11435
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
C1M51_11435
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
C1M51_11435
Enzymes [BR:
metp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
C1M51_11435
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Histidinol_dh
Motif
Other DBs
NCBI-ProteinID:
QAZ39980
UniProt:
A0A4P6H085
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Position
2394162..2395574
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AA seq
470 aa
AA seq
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MRVMMDLALAHTLLPGSTLVGDPATPLLRVHSDTRTLRAGDLFVALKGERFDAHDFLPQA
RAAGAVAAIAEHGLAEAGLAGLQVADSRAALGTLGANWRARMSLPLIAVTGSNGKTTVTQ
MIASILRAWVGDAAFATEGNFNNDIGVPLTLLRLRQDGDTWHRAAVVELGMNHAGEIAEL
ARMAAPTVALVNNAQREHQEFMAGVEAVARENGSVIEALGASGTAVFPSDDAHAALWQAL
AGTRPTLTFSLEGPSDLVAEAVWSGDHWATVLHTPAGATAIRLRVAGWHNVKNALAATAC
ALAAGCPLEAVARGLEAFEPVKGRSQVKALQRGGRTVTLVDDSYNANPDSVRAAIDVLAT
LPGPRWLVLGDMGEVGDQGPAFHAEVGRYAAACGIDALWTAGGASAAAAAAFGPAARAHA
SVAELIAALGPGTHAAPDAASIVVKGSRFMKMEQVIAALQAAGAASPTPH
NT seq
1413 nt
NT seq
+upstream
nt +downstream
nt
atgcgcgtgatgatggatctggcgctcgcgcacaccctgctgccgggctcgacgctggtc
ggcgacccggccacgccgctgctgcgcgtgcacagcgacacccgcacgctgcgcgccggc
gacctgttcgttgcgctcaagggcgaacgcttcgacgcgcacgacttcctgccgcaggcg
cgcgccgccggcgcggtggcggcgatcgccgagcacggtctcgccgaggctggcctggcc
gggctgcaggtggccgacagccgtgccgcgctcggcacgctgggcgcgaactggcgtgcg
cgcatgagcctgccgctgatcgccgtgaccggcagcaacggcaagaccaccgtcacgcag
atgatcgcgagcatcctacgcgcctgggtcggcgacgcagcgttcgcgaccgagggcaac
ttcaacaacgacatcggcgtgccgctcacgctgctgcggctgcgccaggacggcgacacc
tggcaccgcgccgcggtggtggagctgggcatgaaccacgccggcgagatcgccgagctc
gcgcgcatggccgcgccgacggtggcgctggtcaacaacgcgcagcgcgagcaccaggag
ttcatggctggcgtggaggcggtggcgcgcgagaacggcagcgtgatcgaggcgctgggc
gccagcggcacggcggtcttcccgtccgacgacgcgcatgccgcgctgtggcaggcgctg
gccggcacgcggccgacgctgacgttctcgctcgagggcccgtccgatctggtggccgag
gcggtgtggagcggcgaccactgggcgacggtcctgcacacgccggccggcgccaccgcg
atccgcctgcgtgtggccggctggcacaacgtgaagaacgcgctcgccgcgaccgcctgc
gccctggcggcgggctgcccgctggaggcggtggcgcgcggcctcgaggccttcgagccg
gtgaagggccgctcgcaggtcaaggccctgcagcgcggtggccgcacggtgacgctggtg
gacgacagctacaacgccaaccccgactcggtgcgcgcggcgatcgacgtgctggccacg
ctgcctggcccgcgctggctggtgctgggcgacatgggcgaggtcggcgaccagggcccg
gccttccacgccgaggtcggccgctatgcggccgcgtgcggcatcgacgcgctgtggacc
gccggcggcgccagcgccgccgccgccgctgccttcggcccggccgcacgggcccacgcg
agcgtggccgagttgatcgcggcgctgggtccgggcactcacgcggccccggacgcggcg
tccatcgtcgtcaagggctcgcgcttcatgaagatggagcaggtgatcgccgcgctgcag
gccgccggcgccgcgtcgcccaccccgcactga
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