Marmota marmota marmota (Alpine marmot): 107160020
Help
Entry
107160020 CDS
T09644
Symbol
Erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
mmma
Marmota marmota marmota (Alpine marmot)
Pathway
mmma01521
EGFR tyrosine kinase inhibitor resistance
mmma01522
Endocrine resistance
mmma01524
Platinum drug resistance
mmma04010
MAPK signaling pathway
mmma04012
ErbB signaling pathway
mmma04020
Calcium signaling pathway
mmma04066
HIF-1 signaling pathway
mmma04151
PI3K-Akt signaling pathway
mmma04510
Focal adhesion
mmma04520
Adherens junction
mmma04530
Tight junction
mmma05200
Pathways in cancer
mmma05205
Proteoglycans in cancer
mmma05206
MicroRNAs in cancer
mmma05212
Pancreatic cancer
mmma05213
Endometrial cancer
mmma05215
Prostate cancer
mmma05219
Bladder cancer
mmma05223
Non-small cell lung cancer
mmma05224
Breast cancer
mmma05226
Gastric cancer
mmma05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mmma00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
107160020 (Erbb2)
04012 ErbB signaling pathway
107160020 (Erbb2)
04066 HIF-1 signaling pathway
107160020 (Erbb2)
04020 Calcium signaling pathway
107160020 (Erbb2)
04151 PI3K-Akt signaling pathway
107160020 (Erbb2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
107160020 (Erbb2)
04520 Adherens junction
107160020 (Erbb2)
04530 Tight junction
107160020 (Erbb2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
107160020 (Erbb2)
05206 MicroRNAs in cancer
107160020 (Erbb2)
05205 Proteoglycans in cancer
107160020 (Erbb2)
05230 Central carbon metabolism in cancer
107160020 (Erbb2)
09162 Cancer: specific types
05212 Pancreatic cancer
107160020 (Erbb2)
05226 Gastric cancer
107160020 (Erbb2)
05219 Bladder cancer
107160020 (Erbb2)
05215 Prostate cancer
107160020 (Erbb2)
05213 Endometrial cancer
107160020 (Erbb2)
05224 Breast cancer
107160020 (Erbb2)
05223 Non-small cell lung cancer
107160020 (Erbb2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
107160020 (Erbb2)
01524 Platinum drug resistance
107160020 (Erbb2)
01522 Endocrine resistance
107160020 (Erbb2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmma01001
]
107160020 (Erbb2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mmma04147
]
107160020 (Erbb2)
04090 CD molecules [BR:
mmma04090
]
107160020 (Erbb2)
Enzymes [BR:
mmma01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
107160020 (Erbb2)
Protein kinases [BR:
mmma01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
107160020 (Erbb2)
Exosome [BR:
mmma04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
107160020 (Erbb2)
CD molecules [BR:
mmma04090
]
Proteins
107160020 (Erbb2)
BRITE hierarchy
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Haspin_kinase
Kinase-like
Motif
Other DBs
NCBI-GeneID:
107160020
NCBI-ProteinID:
XP_015362160
Ensembl:
ENSMMMG00000019526
UniProt:
A0A8C5ZZ20
LinkDB
All DBs
Position
Unknown
AA seq
1255 aa
AA seq
DB search
MELAAWCRWGLLLALLPPGAAGTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPANANLSFLQDIQEVQGYMLIAHNQVRRVPLQRLRIVRGTQLFEDSYALAVLDNG
DPLDSATPAPGAFPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLA
LTVIDTNRSRACQPCSPACKANHCWGEGSQDCQSLTRTICASGCARCKGTLPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTTCP
YNYLSTDVGSCTLVCPLNNQEVTGEDGTQRCEKCSKPCARVCYGLGMEHLRAARAVTSAN
IQEFAGCKKIFGSLAFLPESFDGDPASNTAALQPEQLKVFETLEEITGYLYISAWPDSLP
DLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHRNTRLCFVHTV
PWDQLFRNPHQALLHSGNRPEDECAGEGLSCYPLCANGHCWGPGPTQCVNCSQFLRGQEC
VEKCRVLQGLPREYVSDRHCLPCHPECQPQNGSETCFGSKADQCVACAHYKDPPSCVARC
PSGVKADVSYMPIWKFPDEEGMCQPCPINCTHSCVDLDDKGCPAEQRASPVTSIIAAVVG
ILLFVVMGLVFGILIKRRRQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVREHRGRLGSQDLLNWCVQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVAEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGTAHRRHRSSSTRSGGGELTLGLEPSEEDPPRSPLAPSEG
AGSDVFDGDLGIGAAKGLQSLPTHDPNPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYV
NQPEVRPQPPSPLEGPLPPVCPAGATLERPKTLSPGKNGVVKDVFAFGGTVENPEYLAPR
GGAAPQPHPPPAFSPAFDNLYYWDQDSSERGSPPGTFEGTPTAENPEYLGLDVPV
NT seq
3768 nt
NT seq
+upstream
nt +downstream
nt
atggagctggcggcctggtgccgctgggggctcctcctcgccctcctgccccccggagcc
gcgggcacccaagtgtgcacgggcacagacatgaagctgcggctcccggccagtcctgag
acccacctcgacatgctccgccacctctaccagggttgtcaggtggtgcagggtaacttg
gaactgacctacctgcccgctaatgccaacctctccttcctgcaggacatccaggaggtg
cagggctacatgctcattgctcacaaccaagtgaggcgagtccctctgcagaggctgcgg
attgtacgaggcacccaactcttcgaggacagctatgccttggcggtgttagacaatgga
gaccctctggacagtgccacccctgctccgggggcttttcctggagggctgcgggagctg
cagcttcgaagccttacagagatcctgaagggaggagtcttgatccagcggaacccccag
ctctgctaccaggacacgattttgtggaaggacatcttccacaagaacaaccagctggca
cttacggtgatagacaccaaccgctcacgggcctgccaaccctgttctccagcctgtaaa
gccaaccactgctggggagaaggttcccaggactgtcagagcctgacacgcaccatttgt
gccagtggctgtgcccgctgcaagggcacgctgcccaccgactgctgccatgagcagtgt
gctgccggctgcacgggccccaagcattcagactgcctggcttgcctccacttcaaccat
agtggcatctgtgaactgcactgcccagccctggtcacttacaacacagacacctttgag
tccatgcccaaccctgagggccgttatacctttggcgccagctgtgtgaccacctgtccc
tacaactacctctctacggatgtgggatcctgcaccctggtctgccctctgaataaccaa
gaagtgacaggggaggacgggacccagcggtgtgagaaatgcagcaagccctgtgctcga
gtgtgctatggtctgggcatggagcatctgcgggcggcgagggcagtgaccagtgccaat
atccaggagtttgctggctgcaagaagatctttgggagcctggcatttttgccagagagc
tttgatggggatcctgcctccaacacggccgctctacaacctgagcagctcaaagtgttt
gagaccctggaggagatcacaggttacctgtacatctcagcgtggccagacagcctgcct
gacctcagtgtcttccagaacctgcgagtcatccggggacgcgttctgcatgatggcgcc
tactcattgaccctgcaagggctgggcatcagctggctgggactgcgttcactgagggag
ctgggcagcgggctggccctcattcaccgcaacacccgcctctgctttgtgcacacggtg
ccctgggaccagctcttccggaacccccaccaggccctgctccacagtggcaaccggccg
gaggatgagtgtgcgggtgagggcctgtcctgctacccactgtgtgccaatgggcactgc
tgggggccagggcccacccagtgtgtcaactgcagccagttccttcggggccaagagtgc
gtggagaaatgccgagtcctgcaggggctccccagggagtatgtgagtgacaggcactgt
ctaccatgccaccccgagtgtcagccccagaatggctcagagacctgctttggatcgaag
gctgaccagtgtgtggcctgtgcccactacaaggaccctccctcctgtgtggctcgctgc
cccagtggtgttaaagctgatgtctcctacatgcccatctggaagttcccggatgaggag
ggcatgtgccagccctgcccaatcaactgcactcactcctgcgtggacctggatgacaaa
ggctgcccagctgagcagagagccagccctgtgacatccatcattgctgctgtggtgggc
attctgctgttcgtggtcatgggactggtctttgggatcctaatcaagcgaaggcgacag
aagatccggaaatacacgatgcggaggctgctgcaggaaaccgagctggtggagccgctg
acacccagtggagccatgcccaaccaggctcagatgcgaatcttgaaagagacagagcta
aggaaggtgaaagttcttggatccggagcttttggcacagtctacaagggcatctggatc
cctgatggggagaatgtgaaaatccctgtggccatcaaagtgttgagggaaaacacatcc
cccaaagccaacaaggaaatcttggatgaagcgtatgtgatggctggtgtgggctccccc
tatgtgtcccgactcctgggcatctgcctgacatccacggtacaactggtgacacagctt
atgccctatggctgcctcctggatcacgtccgagaacaccgtggtcgcctgggctcccag
gacctgctgaactggtgtgtgcagattgccaaggggatgagctacctggaggatgtgcgg
ctcgtgcatagggacctagctgcccggaatgtgctggtcaagagtcccaaccatgtgaag
attacagattttgggttggctcggctgttggacattgatgagacagagtaccatgccgac
gggggcaaggtgcccatcaagtggatggcgttggagtccattcttcgtcggcggttcacc
catcagagtgatgtgtggagctacggtgtcactgtgtgggagctgatgacttttggggcc
aaaccctatgatgggatcccagcccgggagatccctgacctgctggagaaaggggagcgg
ctgccacagcctcccatctgcaccattgatgtctacatgatcatggtcaaatgttggatg
attgactccgaatgtcggccaagattccgggagctggtggctgaattctcccgcatggcc
agggatccccagcgctttgtggtcatccagaatgaggacttgggtccagccagccccttg
gacagcaccttctaccgctcgctgctggaggatgatgatatgggggacttggtggatgct
gaggagtatctggtaccccaacagggcttcttctgcccagaccctgccccaggtgctggg
ggcacagctcaccgcaggcaccgaagctcatccaccaggagtggtggtggtgagctgaca
ctggggctggagccctctgaagaagaccccccaaggtctcctctggccccctcagaaggg
gctggctctgatgtatttgatggtgacctgggaataggggcagccaaggggttgcagagc
ctccccacacacgaccccaaccctctacagcggtacagtgaggaccccacagtacccctg
ccccccgagactgatggctacgttgctcccttgacctgcagcccccagcctgaatatgtg
aaccagccagaggttcggccacagcccccctcacccttagagggtcctctgcctcctgtc
tgccctgctggtgccactctggaaagacccaagactctctcccctgggaaaaatggggtt
gtcaaagacgtttttgcctttgggggtactgtagagaaccccgagtacttggcacccagg
ggaggtgctgcccctcagccccatcctcctcctgccttcagcccagcctttgacaacctc
tattactgggaccaggactcatcagagcggggatctccgcctggcacctttgaagggacc
ccaacagcagagaaccctgagtacctgggcctggatgtgccagtgtga
DBGET
integrated database retrieval system
