Mustela nigripes (black-footed ferret): 132006175
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Entry
132006175 CDS
T09425
Symbol
PDGFRA
Name
(RefSeq) platelet-derived growth factor receptor alpha
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
mnp
Mustela nigripes (black-footed ferret)
Pathway
mnp01521
EGFR tyrosine kinase inhibitor resistance
mnp04010
MAPK signaling pathway
mnp04014
Ras signaling pathway
mnp04015
Rap1 signaling pathway
mnp04020
Calcium signaling pathway
mnp04072
Phospholipase D signaling pathway
mnp04144
Endocytosis
mnp04151
PI3K-Akt signaling pathway
mnp04510
Focal adhesion
mnp04540
Gap junction
mnp04630
JAK-STAT signaling pathway
mnp04810
Regulation of actin cytoskeleton
mnp05163
Human cytomegalovirus infection
mnp05200
Pathways in cancer
mnp05206
MicroRNAs in cancer
mnp05214
Glioma
mnp05215
Prostate cancer
mnp05218
Melanoma
mnp05230
Central carbon metabolism in cancer
mnp05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mnp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
132006175 (PDGFRA)
04014 Ras signaling pathway
132006175 (PDGFRA)
04015 Rap1 signaling pathway
132006175 (PDGFRA)
04630 JAK-STAT signaling pathway
132006175 (PDGFRA)
04020 Calcium signaling pathway
132006175 (PDGFRA)
04072 Phospholipase D signaling pathway
132006175 (PDGFRA)
04151 PI3K-Akt signaling pathway
132006175 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
132006175 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
132006175 (PDGFRA)
04540 Gap junction
132006175 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
132006175 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
132006175 (PDGFRA)
05206 MicroRNAs in cancer
132006175 (PDGFRA)
05230 Central carbon metabolism in cancer
132006175 (PDGFRA)
05231 Choline metabolism in cancer
132006175 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
132006175 (PDGFRA)
05218 Melanoma
132006175 (PDGFRA)
05215 Prostate cancer
132006175 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
132006175 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
132006175 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mnp01001
]
132006175 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
mnp04090
]
132006175 (PDGFRA)
Enzymes [BR:
mnp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
132006175 (PDGFRA)
Protein kinases [BR:
mnp01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
132006175 (PDGFRA)
CD molecules [BR:
mnp04090
]
Proteins
132006175 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
V-set
VEGFR-1-like_Ig-like
Herpes_gE
DUF3475
Kinase-like
Motif
Other DBs
NCBI-GeneID:
132006175
NCBI-ProteinID:
XP_059239906
LinkDB
All DBs
Position
1:245556689..245599726
Genome browser
AA seq
1090 aa
AA seq
DB search
MMGTSLVALLILGCLLPGPGLILCQLSLPSILPNEDEKVVQLNSSFSLRCFGESEVSWQY
PMSEEENPNVEIRNEENNSGLFVTVLEVVNASAAHTGLYTCYYNHTQTEEMELEGRHIYI
YVPDPDVAFVPLGMTDYLVIVEEDDSAIIPCRTTDPETPVTLISSDGVVHASYDSRQGFN
GTFSVGPYICEATVRGKKFQTIPFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFN
NEVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATKEV
KEMKKVTISVHEKGFIEIKPNFSPLEAVDLHEVKHFVVDVQAYPPPKISWLKDNLTLIEN
LTEITTDIEKIQEIRYRSKLKLIRAKEEDSGHYTIVVQNEDDVKSYTFELLTQVPSSILD
LVDDHHGTTGGQTVRCTAGGTPLPDIEWMVCKDIKKCNNETSWAILASNISNIITEVHPR
DRSTVEGRVTFTRVEETIAVRCLAKNLLGAESRELKLVAPTLRSELTVAAAVLVLLVIVI
VSLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRIL
GSGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVN
LLGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSRHPEKPKKELDIFGLNPADDSTRS
YVILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSVLDSEVK
NLLSDDNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGL
ARDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGM
MVDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWHSEPEKRPSFYHLSEIVENLLPGQYK
KSYEKIHLDFLKSDHPAVARMRVDADNAYIGVTYKNEEDKLKDWEGSLDEQRLSADSGYI
IPLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGID
SSDLVEDSFL
NT seq
3273 nt
NT seq
+upstream
nt +downstream
nt
atgatggggacctcccttgtggccctgctgatcttaggctgtctcctgccagggcccggc
ctaatcctctgccagctttcattaccctcgatccttccaaacgaagatgaaaaggtcgtg
cagctgaattcgtccttttctctgagatgctttggggagagtgaagtgagctggcagtac
cccatgtctgaagaagagaaccccaatgtggaaatcagaaatgaggagaacaacagcggc
ctctttgtgactgtgctggaagtggtcaatgcgtccgcggcgcacacaggcctgtacact
tgctattacaaccacacgcagacggaggaaatggagctcgaaggcagacacatctacatc
tatgtgccagacccagatgtagcctttgtacctttgggaatgaccgattatttagtcatc
gtggaggaggatgattctgccatcataccttgtcgcacgactgaccccgagactccggtc
accttgataagcagtgacggggtggtgcacgcctcctatgacagcagacagggcttcaat
gggaccttcagcgtcgggccctatatctgtgaagctaccgttagggggaagaagttccag
accattccatttaatgtttatgctctaaaagcaacatcagaacttgatctagaaatggaa
gctcttaaaactgtgtataagtcaggggagacgattgtggtcacctgtgctgtctttaac
aacgaggtggtcgaccttcagtggacgtaccccggagaagtgaaaggcaaaggcatcacc
atgctggaggaaatcaaggtcccgtccatcaaattggtgtatacgctgacggtccccgag
gccacggtgaaagatagtggagattacgaatgtgctgcccgccaggccaccaaggaggtc
aaagagatgaagaaagtcaccatttctgtccatgagaaagggttcattgaaatcaaaccc
aacttcagcccgttggaagctgtcgacctacatgaagtcaaacatttcgtggtggatgtg
caggcctacccccctcccaagatatcctggctgaaggacaatctgactctgattgaaaat
ctcacagagatcaccacggacatagaaaagattcaggaaatcagatatcggagcaaatta
aagctgatccgtgctaaggaggaagacagtggtcattacacaattgttgttcaaaacgaa
gacgatgtgaagagctatacttttgaactcttaactcaagttccctcttccattctggac
ttggtcgacgaccaccatggcactacggggggccagaccgtgagatgcaccgctggaggg
acgccgcttcctgacatcgagtggatggtttgcaaggatattaagaagtgtaataatgaa
acttcatgggcgattttggccagcaatatctcaaacatcatcacggaggtccacccccga
gacaggagtactgtagagggacgagtgacattcaccagagtggaggagaccatcgctgtc
cgatgtctggccaagaacctccttggggctgagagccgggagctgaagctggtggctccc
acactgcgatccgagctcactgtggccgctgcggtcctcgtgctgctggtgattgtgatc
gtctcactcattgtcctggttgtcatttggaaacagaaaccgaggtatgaaatccgttgg
agggtcattgaatccatcagccctgatggacatgaatatatttatgtggacccaatgcag
ctgccttatgactcgagatgggagtttccaagagatggacttgtgcttggtcggatcctg
ggatctggtgcattcgggaaagtggttgaaggaaccgcctatgggttaagccgctcccag
cctgtcatgaaagtagccgtgaagatgctaaaacccacagccaggtccagtgagaagcag
gctctcatgtcggaactgaagataatgactcacctggggccacatttgaacattgtgaac
ttgctgggagcctgtaccaagtcaggccctatttacatcatcacggagtactgcttctat
ggggatttggtcaactatttgcataagaacagggatagcttcctgagccgccacccggag
aagccgaagaaggagctggacattttcggattgaaccctgcggatgacagcacgcggagt
tacgttattttatctttcgaaaacaacggggactacatggacatgaagcaggctgacacc
acacagtacgtccccatgctggagaggaaggaggtctctaagtactcggacatccagaga
tcgctgtatgatcgcccagcctcctacaagaagaaatctgtgttagactcagaagtcaaa
aacctcctttcggacgataactcagaaggccttactttgttggatttgttgagttttacc
tatcaagttgcgcgaggaatggaatttttggcttcgaaaaactgcgtccaccgggacctg
gctgcccgaaatgtcctcctggcgcaagggaaaatcgtgaagatctgtgactttggtctg
gccagagacatcatgcatgattccaactacgtgtctaaaggcagcaccttcctccccgtg
aagtggatggcccccgagagcatcttcgataatctctacaccacgctgagtgacgtctgg
tcttacggcattctgctctgggagatcttttctcttggaggcaccccctaccctggcatg
atggtggattcgactttctacaataagatcaagagcggctaccggatggccaagcctgac
catgccaccagtgaagtctacgagatcatggtgaagtgctggcacagtgagccagagaag
agaccctccttctatcacctgagtgagattgtggaaaatctgctgcctggacagtacaag
aagagttacgagaagattcacctggatttcctgaagagcgaccaccccgccgtggcgcgc
atgcgcgtggacgccgacaatgcctacatcggcgtcacctacaaaaacgaggaggacaag
ctgaaggactgggagggcagcctggacgagcagcggctgagtgcggacagcggctacatc
atccccctgcccgacatcgacccggtccctgaggaggaagacctgggcaagaggaacaga
cacagctcgcagacctccgaagagagcgctattgagacaggttccagcagctctaccttc
atcaagagagaggacgaaaccatcgaggacatcgacatgatggacgacattggcatagac
tcctcagacctggtagaggacagcttcctgtga
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