Mus pahari (shrew mouse): 110327669
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Entry
110327669 CDS
T05929
Symbol
Th
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
mpah
Mus pahari (shrew mouse)
Pathway
mpah00350
Tyrosine metabolism
mpah00790
Folate biosynthesis
mpah01100
Metabolic pathways
mpah04728
Dopaminergic synapse
mpah04917
Prolactin signaling pathway
mpah05012
Parkinson disease
mpah05030
Cocaine addiction
mpah05031
Amphetamine addiction
mpah05034
Alcoholism
Module
mpah_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
mpah00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
110327669 (Th)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
110327669 (Th)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
110327669 (Th)
09156 Nervous system
04728 Dopaminergic synapse
110327669 (Th)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
110327669 (Th)
09165 Substance dependence
05030 Cocaine addiction
110327669 (Th)
05031 Amphetamine addiction
110327669 (Th)
05034 Alcoholism
110327669 (Th)
Enzymes [BR:
mpah01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
110327669 (Th)
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Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
DUF2330
LTP_2
Motif
Other DBs
NCBI-GeneID:
110327669
NCBI-ProteinID:
XP_021062453
Ensembl:
MGP_PahariEiJ_G0013927
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All DBs
Position
1:complement(112203109..112241576)
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AA seq
500 aa
AA seq
DB search
MPTPSASSPQPKGFRRAVSEQDTKQAEAVTSPRFIGRRQSLIEDARKEREAAAAAAAAAA
AVASSEPGNPLEAVVFEERDGNAVLNLLFSLRGTKPSSLSRAVKVFETFEAKIHHLETRP
AQRPLAGSPHLEYFVRFEVPSGDLAALLSSVRRVSDDVRSATEDKVPWFPRKVSELDKCH
HLVTKFDPDLDLDHPGFSDQAYRQRRKLIAEIAFQYKQGEPIPHVEYTKEEIATWKEVYA
TLKGLYATHACREHLEAFQLLERYCGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSAR
DFLASLAFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLG
ASDEEIEKLSTVYWFTVEFGLCKQNGELKAYGAGLLSSYGELLHSLSEEPEVRAFDPDTA
AVQPYQDQTYQPVYFVSESFSDAKDKLRNYASRIQRPFSVKFDPYTLAIDVLDSPHTIRR
SLEGVQDELHTLTQALSAIS
NT seq
1503 nt
NT seq
+upstream
nt +downstream
nt
atgcccacccccagcgcctcctcgccacagcccaagggcttcagaagagcagtctcagag
caggacaccaagcaggccgaggctgtcacgtccccaaggttcatcggacggcggcagagt
ctcatcgaggatgcccgcaaggagcgggaggcggcagcagctgcggcggcggcggcggcg
gcggtagcctcctcggaacctgggaacccgttggaggctgtggtatttgaggagagggat
ggaaatgctgttctcaacctgctcttctccctgaggggtacaaaaccctcctcactgtct
cgggctgtgaaagtgtttgagacatttgaagccaaaatccaccacttagagacccggcct
gcccaaaggcccctggcgggaagcccccacctggagtactttgtgcgcttcgaggtgccc
agtggagacctggctgccctcctcagttctgtgcgccgggtgtctgacgatgtgcgcagt
gccacagaggacaaggttccctggttcccaaggaaagtgtcagagttggataagtgtcac
cacctggtcaccaagtttgaccctgacctggacctggaccatccgggcttctctgaccag
gcatatcgccagcgccggaagctgattgcagagattgccttccaatacaagcagggtgaa
ccaattccccacgtggagtacacaaaggaggagattgctacctggaaggaggtatacgcc
acgctgaagggcctctatgctacccacgcctgccgggagcacctggaggctttccagctt
ctggaacggtactgtggctaccgagaggacagcatcccacagctggaggatgtgtcccgc
ttcttgaaggagcggactggcttccagctgcgacccgtggctggactactgtctgcccgt
gattttctggccagtctggccttccgtgtgtttcaatgcacacagtacatccgtcatgcc
tcctcacctatgcattcacctgagccggactgctgccacgagctgctgggacacgtaccc
atgttggctgaccgcacatttgcccagttctcccaggacattggacttgcatctctgggg
gcttcagatgaagaaattgagaaactctccacggtgtactggttcactgtggagtttggg
ctgtgtaaacagaacggggagctgaaggcttacggtgcagggctgctgtcttcctatgga
gagctcctgcactccctgtcagaagagcccgaggtccgggcctttgacccagacacagca
gccgtgcagccctaccaggaccaaacctaccagccggtgtactttgtgtcggagagcttc
agtgatgccaaggacaagctcaggaactatgcctctcgtatccagcgcccattctccgtg
aagtttgacccatacaccctggccattgatgtactggacagtccccacaccatccggcgc
tccttggagggggtccaggatgagctgcacaccctgacccaagcactgagtgccattagc
taa
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