Nitrospira defluvii: NIDE0757
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Entry
NIDE0757 CDS
T01281
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
nde
Nitrospira defluvii
Pathway
nde00300
Lysine biosynthesis
nde00550
Peptidoglycan biosynthesis
nde01100
Metabolic pathways
nde01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
nde00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NIDE0757 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NIDE0757 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NIDE0757 (murF)
Enzymes [BR:
nde01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NIDE0757 (murF)
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Ortholog
Paralog
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Abhydrolase_3
Motif
Other DBs
NCBI-ProteinID:
CBK40524
UniProt:
D8PBB5
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Position
721830..723293
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AA seq
487 aa
AA seq
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MREHGNRGVMALFTVEEICEVLSVRPPAGVTPQDLKQRIRRVVTDSRSVRKGDLFIAFQG
ERFDAHTFVPKALAQGAVCAIVQEDYRLPPAPKRTGVPVLLGVRDTLEAYQRLATHYRNR
FPIPVIAITGSNGKTTTKEMVAQVVAQRWKTLKTEGNLNNRIGVPQTLFQLAPRHQAAVI
EMGVDQQGQTTRLCEIARPTIGVITNIGPDHLEFFGSMEGSAQAKAELLDHLPQDGAVVL
NADDEYFDYLAARAQCRVVAFGISPKAAIRAANIRVDEKGGTLFGLVVPGKSRQTEIRIR
AQGQHNVSNALAAAAVGYVLGLSGTAIAEGLAKFRPAAMRSQISLSHGVQVINDCYNANP
ASMKAAVQLLAELGRGKRSIAALGDMLELGTDSKRMHREVGAFLAAQGIGHLLACGVLGR
ELAEGARQAGMASDRITELPDAPAAAAALARMVRQGDVVLVKASRGMRMEQVVEAVMGMR
RVARKAC
NT seq
1464 nt
NT seq
+upstream
nt +downstream
nt
atgcgggagcatgggaatcgcggtgtgatggcgctgtttacagtcgaggaaatatgtgag
gtcttgagtgtcagaccgccggccggcgtcacccctcaggacttgaaacaacgaatccgt
cgcgtggtgaccgattcgcgatcggtgcgcaaaggtgacctcttcatcgctttccaaggc
gagcggtttgatgcgcataccttcgtgccgaaggcgctggcccagggggcggtctgcgcc
atcgtgcaggaggactaccgtttgccgccggcgccgaaacgcaccggcgtgcccgtgctg
ctcggggtgagagatacgctcgaggcctatcaacggctggccacgcactatcgcaaccgg
tttcccattccggtcatcgccatcacggggagcaacggcaagacgacgacgaaggaaatg
gtcgcccaggtggtggcacagcgctggaaaacgctcaagaccgagggcaatctcaataat
cgaatcggagtcccgcagactctgtttcaattggcgcctcgccatcaggccgccgtcatt
gaaatgggggtggatcagcaggggcagaccacccggctgtgcgaaatcgcgagaccgacg
atcggcgtgattaccaacatcggcccggaccatttggagtttttcggcagtatggaaggg
tccgcgcaggccaaagccgagttgctcgaccatttgcctcaggatggggcggtggtgttg
aacgccgacgatgaatattttgactatctcgcggccagggcgcagtgccgcgttgtggcg
ttcgggatatctcccaaagccgccatccgcgcggccaatattcgggtcgatgaaaaaggc
ggaacgctgttcggcctggttgtgccgggaaaaagtcgtcagacggaaattcgcatccgg
gcgcaggggcaacacaatgtgagcaatgccctcgcggcggctgcggtcgggtatgtgttg
gggttatcggggacggccatcgccgaggggctggcgaagtttcgtccggccgcgatgaga
tcgcagatcagcctctcccacggggtgcaggtgatcaacgattgctacaacgcgaatccg
gcctcgatgaaagcggccgttcaactgctggcggaactcggccggggaaaacggtcgatc
gcggcgctgggcgacatgctggagctgggcacggacagcaagcggatgcaccgggaagta
ggggcctttctggccgcacaagggatcggacatctgcttgcctgcggtgtattgggacga
gagttggccgaaggcgcccggcaggccgggatggcgtccgaccgcatcacggaattgccc
gatgcgccggcggccgctgctgccctggcgcggatggtccggcaaggcgacgtggtgctg
gtcaaggcctcgcggggtatgcgcatggagcaggtcgtggaagccgtgatggggatgcga
cgagtcgcacgaaaggcctgctag
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