Cutibacterium acnes KPA171202: PPA0754
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Entry
PPA0754 CDS
T00188
Name
(GenBank) UDP-N-acetylmuramyl pentapeptide synthase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
pac
Cutibacterium acnes KPA171202
Pathway
pac00300
Lysine biosynthesis
pac00550
Peptidoglycan biosynthesis
pac01100
Metabolic pathways
pac01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
pac00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
PPA0754
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
PPA0754
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
PPA0754
Enzymes [BR:
pac01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
PPA0754
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase
Mur_ligase_C
LpxD
Motif
Other DBs
NCBI-ProteinID:
AAT82510
UniProt:
Q6A9Q6
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All DBs
Position
828645..830102
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AA seq
485 aa
AA seq
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MRVLDVATLAQWVEAAPVNDSAQVGPDVVIDTRKVTPGALFIALPGTRVDGHDFTQAAQD
TGAAAVLVTRRTDAQLPHLVVDDGQAGLSRLARHVVATERERGMRTIALTGSSGKTSTKD
MLAQILETFGPTVAPVGSFNNEIGVPLTACRSNENTSFLVSEMGTRGLGHISWLTSIVTP
DVAMVLNVGNAHLGEFGSREVIAQAKGEIVEALSVDGWAVLNAADTLVAGMAPRTRGHIA
WFSPDADHRRPDADIEVWAESTHADDLDRHSFTLAARRGESTWRSPVRLMTMGAHQVANA
VAATAAALAALAMNDDIDDQTVTRIAEALSNAVSRSAMRMQLRERADGLVLVEDCYNANP
DSMAASLTAMGHVLATRRARDPQTRGVAVLGDMLELGQDSARLNAESGRLAAHAGFDVII
AVGDEAENIAEGARAEGARVIVSTVEDASGSLGWTSHDVVLLKASRGLALERVGREVFEE
REAQA
NT seq
1458 nt
NT seq
+upstream
nt +downstream
nt
atgagagttctcgacgttgccaccctcgcgcagtgggtcgaagcagcaccggtaaatgat
tctgcccaggtgggcccggacgtcgtcattgatacccggaaggtaactccgggcgctctg
tttatcgctcttcccggcacccgggtagacggtcatgacttcactcaggcggctcaggac
acgggcgctgccgctgtcctggtcactcggcgcaccgacgcacagttgccccatctcgtt
gttgacgatggtcaagccggcctatctcgactggcgcgtcatgtcgtggcgactgaacga
gaacgtggcatgcgtaccatcgctttgactggttccagcggtaagacaagcaccaaggac
atgctggcccagatccttgagacttttggcccaacggtggctccggtgggatcgttcaac
aatgaaatcggagttcctctgacggcgtgccgcagtaacgagaacacctctttcttggtg
tcggaaatggggactcgcggtctgggtcatatctcctggctcacctccatcgttactccc
gacgtagccatggtcctcaacgtcgggaatgcccacctgggcgagtttggttcgcgagag
gtcattgcccaggctaagggtgagatcgttgaggccctcagcgttgacggttgggctgtg
ctcaacgccgccgatacccttgtcgccgggatggcaccgcgcacccgtggacatattgca
tggttcagccctgatgctgaccatcgtcgcccagatgccgacatcgaggtgtgggccgaa
tcaacccatgccgacgacctggatcgtcactcctttacccttgccgcccgccggggtgag
tccacctggcgtagccctgtccggctgatgacgatgggtgctcatcaggtcgcaaatgcc
gtggctgctactgctgctgcgctggcagccttggctatgaatgacgacatcgatgaccaa
actgtcactcggatcgccgaggcgctcagcaacgccgtgtccaggtcagctatgagaatg
cagttgcgtgaacgcgccgatggcctggtgctggtcgaggactgctacaacgccaaccct
gactcgatggccgcttcgttgacagcgatggggcatgtcttggcgacgcgccgagctcgg
gaccctcagactaggggcgtcgccgtcttgggcgacatgctcgagcttggacaggactct
gctcgtctcaatgccgagtccggtcggctagcagcccacgctggattcgacgtcattatc
gctgttggcgatgaggccgagaacattgccgaaggtgcccgggccgaaggcgcacgtgtg
attgtttccaccgtggaagatgcttctggatcactaggttggacctcacacgatgtcgtt
ttactcaaagcttccagaggtctggccttggagcgagtaggacgcgaagtgttcgaggaa
agagaggcccaggcgtga
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