Pseudomonas aeruginosa M18: PAM18_4507
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Entry
PAM18_4507 CDS
T01973
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
paf
Pseudomonas aeruginosa M18
Pathway
paf00300
Lysine biosynthesis
paf00550
Peptidoglycan biosynthesis
paf01100
Metabolic pathways
paf01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
paf00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
PAM18_4507 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
PAM18_4507 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
PAM18_4507 (murF)
Enzymes [BR:
paf01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
PAM18_4507 (murF)
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AEO76988
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Position
complement(4989406..4990782)
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AA seq
458 aa
AA seq
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MLEPLRLSQLTVALDARLIGEDAVFSAVSTDSRAIGPGQLFIALSGPRFDGHDYLAEVAA
KGAVAALVEREVADAPLPQLLVRDTRAALGRLGALNRRKFTGPLAAMTGSSGKTTVKEML
ASILRTQAGDAESVLATRGNLNNDLGVPLTLLQLAPQHRSAVIELGASRIGEIAYTVELT
RPHVAIITNAGTAHVGEFGGPEKIVEAKGEILEGLAADGTAVLNLDDKAFDTWKARASGR
PLLTFSLDRPQADFRAADLQRDARGCMGFRLQGVAGEAQVQLNLLGRHNVANALAAAAAA
HALGVPLDGIVAGLQALQPVKGRAVAQLTASGLRVIDDSYNANPASMLAAIDILSGFSGR
TVLVLGDMGELGSWAEQAHREVGAYAAGKVSALYAVGPLMAHAVQAFGATGRHFADQASL
IGALATEQPTTTILIKGSRSAAMDKVVAALCGSSEESH
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgcttgagcctcttcgcctcagccagttgacggtcgcgctggacgcccgcctgatcggc
gaggacgccgtcttttcggcggtttccaccgacagtcgcgccatcgggcccggccaactg
ttcattgccctgagtgggccgcgtttcgacggccacgactatctcgccgaggttgccgcc
aagggcgcggtggctgcgctggtggagcgcgaagtcgccgacgcgcccctgccgcaattg
ctggtgcgcgatacccgtgcggccctggggcgactgggcgcgctgaaccggcgcaagttc
accggcccgctggcggccatgacgggctccagcggcaagaccacggtcaaggagatgctc
gccagcatcctgcgtacccaggccggcgatgccgagtcggtgctggctacccgtggcaat
ctgaacaacgacctcggcgtaccgctgaccctgctgcaactggcgccgcagcaccgtagc
gcagtgatcgaactgggcgcctcgcgcatcggcgagatcgcctacacggtcgagctgacc
cgcccgcacgtggcgatcatcaccaatgccggaaccgcccatgtcggcgagttcggcgga
ccggagaagatcgtcgaggcgaagggcgagatactcgaagggctggccgccgacggcacc
gccgtactgaacctggacgacaaggccttcgacacctggaaggcccgtgccagcggccgt
ccgttgctgactttctccctcgaccggccccaggccgatttccgcgccgccgatctgcag
cgcgatgcgcgcggctgcatgggcttcaggctgcagggcgtagcgggtgaagcgcaggtc
cagctcaacctgctggggcggcacaatgtcgccaatgccctggctgccgccgctgccgcc
catgcactgggcgtgccgctggatgggatcgtcgccgggctgcaggcgctgcagccggtc
aagggccgcgcggtagcgcaactgaccgccagcgggctgcgtgtgatagacgacagctac
aacgccaaccccgcgtcaatgctggcggcgattgatatactgagcggcttttccgggcgc
accgtcctggtcctcggagacatgggcgaactcggttcctgggccgagcaggcccaccgc
gaggtgggcgcctacgccgctggcaaggtgtccgcgctctatgcagtcggaccgctgatg
gcccacgccgtacaggcgttcggcgccacgggccggcacttcgccgaccaggccagcctg
atcggggcgctggccaccgaacaaccgacaaccaccattttgatcaagggttcccgcagt
gcggcgatggacaaagtcgtcgcggcgctgtgcggttcctccgaggagagtcactaa
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