KEGG   Prionailurus bengalensis (leopard cat): 122484125
Entry
122484125         CDS       T07574                                 
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase
  KO
K00501  tyrosine 3-monooxygenase [EC:1.14.16.2]
Organism
pbg  Prionailurus bengalensis (leopard cat)
Pathway
pbg00350  Tyrosine metabolism
pbg00790  Folate biosynthesis
pbg01100  Metabolic pathways
pbg04728  Dopaminergic synapse
pbg04917  Prolactin signaling pathway
pbg05012  Parkinson disease
pbg05030  Cocaine addiction
pbg05031  Amphetamine addiction
pbg05034  Alcoholism
Module
pbg_M00042  Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:pbg00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    122484125 (TH)
  09108 Metabolism of cofactors and vitamins
   00790 Folate biosynthesis
    122484125 (TH)
 09150 Organismal Systems
  09152 Endocrine system
   04917 Prolactin signaling pathway
    122484125 (TH)
  09156 Nervous system
   04728 Dopaminergic synapse
    122484125 (TH)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05012 Parkinson disease
    122484125 (TH)
  09165 Substance dependence
   05030 Cocaine addiction
    122484125 (TH)
   05031 Amphetamine addiction
    122484125 (TH)
   05034 Alcoholism
    122484125 (TH)
Enzymes [BR:pbg01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.16.2  tyrosine 3-monooxygenase
     122484125 (TH)
SSDB
Motif
Pfam: Biopterin_H TH_ACT TOH_N LTP_2
Other DBs
NCBI-GeneID: 122484125
NCBI-ProteinID: XP_043437948
LinkDB
Position
D1:114367157..114374550
AA seq 494 aa
MPTPNAASPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREKAEAAGAASS
EPGDPLETAVFKEKDGRATLNLIFTLRGAKASLSRAVKAFETFEAQIRHLETRPAQRPRA
GGPHLEYFVCCEVPSADLPALLSSVRRVAEDVRGARENKVFWFPRKVSELDKCHHLVTKF
DPDLDLGHPGFSDQAYRQRRKLIAEIAFQYKHGDPIPRVEYTAEEIATWKEVYTTLKGLY
VTHACREYLEAFQLLERFSGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASL
AFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEI
EKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEEPEIRAFDPDAAAVQPYQ
DQTYQPVYFVSESFSDAKDKLRNYASRIQRPFSVKFDPYTLAIDVLDSPHAIWRSLQGVQ
DELHTLTHALSAIG
NT seq 1485 nt   +upstreamnt  +downstreamnt
atgcccactcccaacgccgcctcgccgcaggccaagggcttccgcagggccgtctccgag
ctggacgccaagcaggccgaagccatcatgtccccgcgcttcatcgggcgacggcagagc
ctcatcgaggacgctcgcaaggagcgagagaaggcagaggccgcgggggccgcctcctcg
gagcccggggaccccctggagaccgccgtgttcaaggagaaggacggaagggccacgctc
aacttgatcttcaccctgcggggcgccaaagcctcactgtcccgggccgtgaaggcgttc
gagacgttcgaggcccaaatccggcacctggagacccggccggcccagaggccgcgcgca
gggggcccccacctggaatactttgtgtgctgtgaggtgcccagcgcggacctgcccgcc
ctgctcagctccgtgcgccgggtggctgaggacgtgcggggcgccagggagaacaaggtc
ttctggttcccaaggaaagtttccgagctggacaagtgccaccacctggtcaccaagttt
gaccctgacctggacttgggtcacccgggtttctcggaccaggcgtaccggcagcgcagg
aagctgatcgcggagatagccttccagtacaagcatggcgaccccattccccgtgtggag
tacacggccgaggagatcgccacctggaaggaggtctacaccaccctcaagggcctctac
gtcactcacgcctgccgggaatacctggaggctttccagctgctggagcgtttcagcggg
taccgggaggacagcatccctcagctggaagacgtgtcccgcttcctgaaggagcggaca
ggcttccagctgcggcccgtggccggcctgctgtccgcccgggacttcctggccagcctg
gccttccgagtgttccagtgcacccagtacatccgacacgcctcctcgcccatgcactcc
ccggagccggactgctgccacgagctgctggggcacgtgcccatgctggccgaccgcacc
ttcgctcagttctcccaggacatcgggctcgcgtccttgggggcttccgacgaggagatt
gagaagctgtccacgctgtactggttcacggtggagttcgggctatgcaagcagaatggg
gaggtgaaggcctacggtgctggactgctgtcctcctatggggagctcctgcactctctg
tctgaggagcccgagatccgggccttcgacccggatgctgcagccgtacagccttaccag
gaccagacttaccagcccgtctacttcgtgtccgagagtttcagcgacgccaaggacaaa
ctcaggaactatgcttcccgcatccagcgccccttctccgtgaagtttgacccgtacacg
ctggccatcgacgtgctggacagtccccatgccatctggcgctccctgcagggcgtccag
gacgagctgcacaccctcacccatgcgctgagcgccatcggctag

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