Puma concolor (puma): 112851004
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Entry
112851004 CDS
T08890
Symbol
KMT2B
Name
(RefSeq) LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2B
KO
K14959
[histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:
2.1.1.354
]
Organism
pcoo
Puma concolor (puma)
Pathway
pcoo00310
Lysine degradation
pcoo01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
pcoo00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
112851004 (KMT2B)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
pcoo03000
]
112851004 (KMT2B)
03036 Chromosome and associated proteins [BR:
pcoo03036
]
112851004 (KMT2B)
Enzymes [BR:
pcoo01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.354 [histone H3]-lysine4 N-trimethyltransferase
112851004 (KMT2B)
Transcription factors [BR:
pcoo03000
]
Eukaryotic type
Zinc finger
CXXC CpG-binding proteins
112851004 (KMT2B)
Chromosome and associated proteins [BR:
pcoo03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
112851004 (KMT2B)
HMT complexes
MLL3/MLL4 complex
112851004 (KMT2B)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
SET
FYRC
FYRN
PHD
zf-CXXC
zf-HC5HC2H
zf-HC5HC2H_2
Bromodomain
Motif
Other DBs
NCBI-GeneID:
112851004
NCBI-ProteinID:
XP_025770300
UniProt:
A0A6P6H3G9
LinkDB
All DBs
Position
Unknown
AA seq
2721 aa
AA seq
DB search
MAAAAGGGSCPGPGSARGRFPGRPRGSGGGGGRGGRGSGAERVRVALRRGGGATGPGGAE
PGEDTALLRLLGLRRGLRRLRRLWAGPRIQRGRGRGRGRGWGPSRGCVPEESSDEESDDE
EFQGFHSDEDVAPSSLRSALRSQRGRAPRGRGRKHKTTPIAPPRLADVAPTPPKTPARKR
GEEGTERMVQALTELLRRAQAPPAPRGRTCEPSTPRRSRGRPPGRPAGPCRKKQQAVVVA
EAAVTIPKPEPPPPVVPVKHRTGSWKCKEGPGPGPGTPKRGGQAGRGGRGGRGRGRGGLP
LVIKFVSKAKKVKMGQLSLGVESGQGQDQREESWQDAPQGRAGSGQGEGPCWRKEQKLEE
EREKETEEKKGKEKEEEKVEGAGPEEMMLAEEKEEAELPSPPSTPPELPAPAAPAAPPPA
PPPPPPPPPPLCPPPPPVSPLPPPSPPPPPAPEEQEESPPPVVPAHAQEEAGVLTPSQXA
DVTGSETLPEGTPPTPTPSTTTGGPLEDSPTVAPKSTTFLKKYRTVYMPVVMLSLSQVHH
PDHLACSMTEAYRPKVSLTLLKAPPVAMSPLAPPEAATAPTHRRAPTPPSTPVPLPEKRR
SILREPTFRWTSLTRELPPPPPAPPPAPPPLPAPVTPSRRPLLLRAPQFTPSEAHLKIYE
SVLTTPLGAPEAPEPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPVVATPVKAEVPLPGA
PTLSNGQQPQPQAQLQQPLQALQTQLLPQALPPQQPQLQPQLQLQPQPPPQQPPPLEKAR
VAGLGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQKVASLLPPSPGGQMEEVVGTVKQL
SDRGSVRSEDESMETKRERPSGPESPVQGPRIKHVCRHAAVALGQARAMVPEDVPRLSAL
PLRDRQDIATEDTSSASETESVPSRSRRGKVESAGPGGDSEPAGSGGTLAQTPRRSLPSH
HGKKMRMARCGHCRGCLRVQDCGSCVNCLDKPKFGGPNTKKQCCVYRKCDKIEARKMERL
AKKGRTIVKTLLPWDSDESPEASPGPPGPRRGAGAGGPREEVVAPPGPEEQDSLLLQRKS
ARRCVKQRPSYDIFEDSDDSEPGGPPAPRRRTPRENELPVPEPEEQSRPRKPTLQPVLQL
KARRRLDKDALAPGPFTSFPNGWTGKQKSPDGVHRVRVDFKEDCDLENVWLMGGLSVLTS
VPGGPPMVCLLCASKGLHELVFCQVCCDPFHPFCLEEAERPLPQHHDTWCCRRCKFCHVC
GRKGRGSKHLLECERCRHAYHPACLGPSYPTRATRKRRHWICSACVRCKSCGATPGKNWD
VEWSGDYSLCPRCTQLYEKGNFCPICTRCYEDNDYESKMMQCAQCDHWVHAKCEGLSDED
YEILSGLPDSVLYTCGPCAGATHPRWREALSGALQGGLRQVLQGLLSSKVAGPLLLCTQC
GQAGKQLHPGPCDLQAVSRRFEEGHYKSVHSFMEDMVGILMKHSEEGETPERRAGGQMKG
LLLKLLESAFGWFDAHDPKYWRRSTRLPNGVLPNAVLPPSLDHVYAQWRQQEPEIPESGQ
PPGDPSAAFQGKDPAAFSHLEDPRQCALCLKYGDADSKEAGRLLYIGQNEWTHVNCAIWS
AEVFEENDGSLKNVHAAVARGRQMRCELCLKPGATVGCCLSSCLSNFHFMCARASYCIFQ
DDKKVFCQKHTDLLDGKEIVTPDGFDVLRRVYVDFEGINFKRKFLTGLEPDAINVLIGSI
RIDSLGTLSDLSDCEGRLFPIGYQCSRLYWSTVDARRRCWYRCRILEYRPWGPREEPVHL
EAAEENQTIVHSPTPSSEPPDHVDPPPDTDALIPGAPEHHSPVQNLDPPLRPDLNIAPPP
APRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHIPTVGDLDFPAPPRRSRR
PSPLTPRLPPSRRASPPLRTSPQLRVPPPTSVVRALTPTSGELAPPGPAPSPPPPPEDLG
PDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAVGSSHGGPGDSSEEEASPTPRY
VHFPVTVVSGPALAPGALPGTPRIEQLDGVDDGTDSEAEAVQQPRGQGTPPSGPGVGRAG
VIGAAGDRTRPPEDLPSEIVDFVLKNLGGPGEGGAGPREEPLPPAPPLANGSQPSQGLPP
SPADPTRTFAWLPGAPGVRVLSLGPAPEPPKPATSKIILVNKLGQVFVKMAGEGEPVSPP
VKQPPLPPPIPPTAPASWTLPPGPLLGVLPVVGVVRPAPPPPPPPLTLVLSSGPPSPPHQ
AIRVKRVSTFSGRSPPAPPPNKTPRLEEDGESLEDAPQGPGLSGSGFSRVRMKTPTVRGV
LDLDEPGEPTGEESPRPLQDRSPLLSLPEGGPPRAPDGPPDLLLESQWHHYSGEASSSEE
EPPSPEDKENQAPKRAGPHLRFEISSEDGFSVEAESLEGAWRTLIEKVQEARGHARLRHL
SFSGMSGARLLGIHHDAVIFLAEQLPGAQRCQHYKFRYHQQGEGQEEPPLNPHGAARAEV
YLRKCTFDMFNFLASQHRVLPEGATCDEEEDEVQLRSTRRATSLELPMAMRFRHLKKTSK
EAVGVYRSAIHGRGLFCKRNIDAGEMVIEYSGIVIRSVLTDKREKFYDGKGIGCYMFRMD
DFDVVDATMHGNAARFINHSCEPNCFSRVIHVEGQKHIVIFALRRILRGEELTYDYKFPI
EDASNKLPCNCGAKRCRRFLN
NT seq
8166 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggcggcgggcggcggcagttgccccgggcctggctccgcgcggggccgcttc
ccgggccggccgcggggctccggcgggggcgggggccgcggcggacggggcagcggagcc
gagagagtgcgggtagctctgcggcgcggtggcggcgcgacggggccgggcggagccgag
cctggggaggacacggccctgctccgtttgctggggctccgccggggcctgcgccggctc
cgccgcctgtgggccggcccgcgcattcagcggggccgaggcaggggccggggccggggc
tggggccccagccggggctgcgtgcctgaggagagcagtgacgaggaatccgacgatgag
gagtttcagggttttcattcagatgaagatgtggcccccagttccctgcgctctgcgctc
cgatcccagcgaggtcgagccccccgaggtcggggccgcaagcataagacgacccccatt
gcgcctcctcgcctagcagatgttgctcctacccccccaaagactcctgcccggaaacgg
ggtgaggaaggcacagaacggatggtacaggcactgactgaacttctccggcgggcccag
gcacccccagccccccggggccggacatgtgagccttccactccacgtcggtctcgggga
cggcccccaggacggccagcaggcccctgcaggaagaagcaacaagctgtagtggtggca
gaagcagctgtgacaatccccaaacccgagcccccacctcctgtggttccagtaaaacac
cgaactggcagctggaagtgcaaggaggggcccggcccaggacctgggacccctaagcgt
ggaggacaggctgggcgaggaggccgtggaggtagaggccgaggccgaggcgggctccct
ctcgtcatcaagtttgtttcaaaggccaaaaaagtgaagatgggacagttgtccttggga
gttgaatcaggtcagggtcaagatcaacgtgaggagagctggcaggatgccccccaagga
agagctggatctggacagggagagggcccctgctggaggaaagagcaaaagctggaggag
gagagagagaaggagacagaagagaagaaaggcaaggagaaggaggaagagaaggtagag
ggagctggacctgaagagatgatgctggcggaggaaaaggaagaggcagagctgccatcc
ccaccctcgactcctccagagcttccagcccctgcagcccctgcagcccccccacccgct
ccaccccctccaccccctccaccccccccactttgtcctccaccacccccagtgtcccct
ctgcccccaccatcacctccaccacctcctgccccagaggagcaggaagaatctcctcct
ccagtggttccagctcatgctcaggaagaggccggcgtcctgactcccagccagnctgca
gacgtgactggctcggagacattgccagaaggtactcctcccactccgacccccagcacc
accacgggaggccctctggaagacagccccactgtggcccccaaaagtaccaccttcctg
aagaagtatcgtacggtttatatgcctgtggtgatgttatcgctctcccaggttcatcat
ccagatcacttggcatgttctatgaccgaggcctacaggcctaaggtgagtctcacccta
ctcaaggctcctcctgttgccatgtccccactcgcccccccagaagccgcaacagctccc
actcacaggcgtgccccaactcccccctctaccccagtcccgcttcctgaaaagagacgg
tccattctaagggaacccacatttcgctggacctcactgacccgggaactgccccctcct
cctcctgctcctccaccggccccacctccacttcctgcccctgtcactccatcccggagg
cccctgctccttcgggcgcctcagtttaccccaagcgaagcccacctgaagatctacgaa
tcggtgcttactactcctcttggggcccctgaagcccctgagccagagcctcctcccgcc
gatgactctccagctgagcctgagccacgggcagtgggccgcaccaaccacctcagcctg
cctcgatttgcccctgtggtcgccactcctgtcaaggccgaggtgccccttcctggggcg
ccaactctgagcaatgggcagcagcctcagcctcaggctcagctacagcagcccctacag
gccttgcaaacccagctgctgccccaggcattaccaccacagcagccacaattacagcca
cagttacaactgcagccacagccgccaccacagcagccgccaccactggaaaaggcccgt
gttgcaggcttgggttccttaccactgtctggtgtggaggagaaaatgttcagcctcctc
aagagagccaaggtgcagctgttcaagatcgatcagcagcagcagcagaaggtggcgtct
ttgttgccgccgagccctggagggcagatggaggaagtcgtggggactgtcaagcaactc
tcagatagaggttctgtcaggtctgaagatgaatcgatggaaactaagagagagagaccg
tcgggccccgagtcccccgtgcaaggcccccgcatcaaacatgtctgtcgtcatgctgct
gtggccctaggtcaggcccgggccatggtgcccgaagacgtcccccgcctcagtgctctt
cctctccgggatcggcaggacatcgccacggaggatacgtcatcagcatctgagactgag
agtgtcccatcacggtctcggcggggaaaggtggagtcagcagggcctgggggagactca
gagcctgccgggtctggagggaccctggcccaaacgccccggcgctcgctgccctcccat
catggcaagaagatgcggatggcacggtgtggacactgtcggggctgcctgcgtgtgcag
gactgtgggtcctgtgtcaactgcctggacaagcccaagtttgggggccccaacaccaag
aagcagtgctgtgtataccggaagtgtgacaagatagaggctcggaagatggaacggttg
gctaaaaaaggccggacgatagtgaagacgctgttgccctgggattccgatgaatctcct
gaggcctcccctggtcctccaggcccacgccggggggcgggagctggggggccccgggag
gaggtggtggcccccccagggcccgaggagcaggactccctcctactgcagcgcaagtca
gcccggcgctgcgtcaaacagcgaccctcctatgatatcttcgaggactcggatgactca
gagcctgggggtccccctgctccccggcgtcggaccccccgagagaatgagctaccagta
ccagaacctgaggagcagagccggccccgcaaacccaccctgcagcctgtgttgcagctt
aaggcccgaaggcgcctggacaaggacgctctggcccctggcccctttacttcttttccc
aatggttggactggaaaacagaagtcccctgacggagtgcaccgggtccgtgtggatttt
aaggaggattgtgacctggagaacgtgtggctgatgggcggcctcagtgtgctcacctct
gtgccaggggggccgccaatggtgtgcttgctgtgtgccagtaaaggcctgcatgagctg
gtgttctgccaagtctgctgtgaccctttccatccattctgtctggaggaggccgaacgg
cccctgccccaacatcatgacacctggtgctgccgccgctgcaagttttgccacgtctgt
gggcgcaaaggccggggatccaagcacctcctggagtgtgagcgctgccgccatgcttat
catccagcctgcctggggcccagctacccaacccgggccacacgcaaacggcgccactgg
atctgctcagcctgcgtacgctgtaagagctgtggggcgactccagggaagaactgggac
gtcgagtggtctggagattacagcctctgccccaggtgcacccagctctatgagaaagga
aatttctgcccaatctgcacacgctgctatgaagacaacgactacgagagcaagatgatg
cagtgtgcacagtgtgaccactgggtgcacgccaagtgcgagggactctcggatgaagat
tatgagatcctttctgggctgccagactccgtgctatatacctgcggaccgtgtgcgggg
gccacgcacccccgctggcgagaggccctgagtggggccttgcaggggggcctacgccag
gtgctccagggcctactgagctccaaggtggcgggcccattgctgctgtgcactcagtgt
gggcaggctggaaagcagctgcacccggggccctgtgatctgcaagccgtgagtcggcgg
ttcgaggaaggccactacaagtccgtgcacagctttatggaggacatggtgggcatcctg
atgaagcactcagaagaaggagaaaccccagagcgccgggctggaggccagatgaagggg
ctcctactgaagctgctagagtctgcgttcggctggttcgacgcccatgaccccaagtac
tggcgacggagtacccggctgccgaacggagttcttcccaatgccgtgttacctccatcc
ttggaccatgtctacgctcagtggaggcagcaggaaccagagatcccagaatcagggcag
cctccaggggacccctcagcagcttttcagggcaaggatccagctgctttctcacacctg
gaggacccccgtcagtgtgcgctctgcctcaaatatggggatgcagactctaaggaggcg
ggacggctcctatacattgggcagaatgagtggacacatgtcaactgtgccatttggtca
gctgaagtgtttgaggaaaatgatggctccctcaaaaacgtgcatgctgctgtagctcga
gggaggcagatgcgctgtgagctctgcctgaagcctggagccacggtgggctgctgcctt
tcctcctgcctcagcaacttccacttcatgtgcgcccgggccagctactgcatcttccag
gacgacaagaaagttttctgccagaaacacacagacctgctggatggcaaggagattgtg
acccccgatgggtttgatgttctccgccgagtctatgtggactttgagggcatcaacttt
aagcgaaagttcttgacggggctcgaacctgatgccatcaatgtgctcattggttccatc
cgaattgactccttgggtaccctgtctgatctctcggactgcgagggacggctcttcccc
attggctaccagtgctcccgtctgtactggagcacagtggatgctcggcggcgctgctgg
tatcggtgtcgtattctggagtatcgtccgtggggtccaagggaagagccagttcacctg
gaggcagcagaggagaaccagaccattgtgcacagccctaccccttcctcagaacccccg
gatcatgtggaccccccgccagatacagatgccctcatccctggagctcctgagcaccac
tcacctgttcagaacctggaccccccacttcggccagatctcaacattgcccctcctcca
gccccccgttccttctcaggggctcgaatcaaagtgcccaactactcaccatcccggagg
cccttggggggtgtctcctttggacccctgccctcccctggaagtccatcttctctgacc
caccacatccctacggtgggagacctggactttccagctccccccagacgctcccgtcgt
cccagccccctgaccccaaggctgccaccgtcgcggcgggcctctccccctctcagaacc
tccccacagctcagggtgccccctcctacctcagtcgttagagccctcacacctacctca
ggggagctggctccccctggcccagccccgtctcctccaccaccccctgaagacctgggc
ccagactttgaggacatggaggtggtgtcaggactgagtgctgctgacctggactttgcg
gccagcctgctggggactgagcccttccaggaagagattgtggccgcaggggcagtgggg
agcagccacgggggtccaggggacagctcagaggaggaggctagccctaccccccgctat
gtccacttccctgtgactgtggtgtctggccctgccctggcccctggtgccctccctgga
accccccgcatcgaacagctggacggagtggatgacggcacagacagcgaggcagaggca
gtccagcagcctcggggccaggggactcctccttcagggccaggagtgggccgggctggg
gtcatcggggctgcaggggacagaacccgacctcctgaggacttgccgtcagaaattgtg
gattttgtgttgaagaacctaggagggcctggagagggaggtgctggacccagagaggaa
cccctccccccagcacctcccctggccaatggcagccagccttcccagggcctaccccct
agcccagctgaccccactcggacgtttgcctggctccctggggccccaggggtccgggta
ttgagcctgggccctgcccctgagccccccaaacccgccacatccaaaatcatccttgtc
aacaagttggggcaagtgtttgtgaagatggctggggagggtgaacccgtctcaccccca
gtgaagcagccacctctgccccctcccatcccccctacagcccctgcttcctggactctg
cccccaggaccgctgctgggtgtgttgccagtggtaggggtggtccgccccgccccaccc
ccaccccctcctccactgaccctggtgttgagcagtggaccccccagcccaccccatcag
gccatccgcgtcaagagggtgtccaccttctctggccgttccccaccagcgcctccccca
aacaagactccccggctggaggaagatggagagtccttggaggatgccccccagggtcca
gggcttagtggcagcgggtttagccgagtaaggatgaaaacgcccacagtgcgtggagtt
cttgacttggatgagcctggggagcccacgggggaggaaagcccaaggcccctccaggac
cggtcccctctgctgtcactcccagaaggtggtcctcctcgggcccctgatggtcccccc
gacctgctgcttgagtcccagtggcaccactactcaggtgaggcttcgagctccgaggaa
gagcctccatccccagaggacaaagagaaccaggcccccaaacgggctggcccacatctg
cgctttgagatcagcagtgaggatgggttcagcgtggaggcagagagcttggagggggca
tggagaactctgattgagaaggtgcaagaggcccgagggcacgcccgcctccgacatctc
tccttcagtggaatgagcggggcaaggctcctgggcatccaccacgacgctgtcatcttc
ctggcagagcagcttcccggggcccagcgctgccagcactataagttccgctaccaccag
cagggagagggccaggaggaaccacccctgaatccccacggggcagcccgtgccgaggtc
tatctccggaagtgtacctttgacatgttcaacttcctggcctcccagcaccgggtgctc
cctgagggagccacctgtgacgaggaagaggatgaggtgcagctcaggtcaaccagacgt
gccaccagcctggagctgcccatggccatgcgctttcgccacctcaagaagacatccaaa
gaggctgtgggtgtctacagatctgccatccatgggcggggcctgttctgtaagcgcaac
atcgatgccggcgagatggtcattgagtattccggtatcgtcattcgctctgtgctgact
gacaagcgggagaagttctacgacgggaagggtatcgggtgctacatgttccgcatggat
gactttgatgtggtggatgccacaatgcacggcaatgctgcccgtttcatcaaccactcg
tgtgagcccaactgcttctctcgagtcatccacgtggagggccagaagcacatcgtcatc
ttcgccctgcgccgcatcctacgtggtgaggagctcacctatgactacaagttccccatt
gaggatgccagcaacaagctgccctgcaactgtggcgccaagcgctgccgtcggttcctg
aactga
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integrated database retrieval system
