Panthera tigris altaica (Amur tiger): 102961961
Help
Entry
102961961 CDS
T02988
Symbol
ERBB2
Name
(RefSeq) erb-b2 receptor tyrosine kinase 2
KO
K05083
receptor tyrosine-protein kinase erbB-2 [EC:
2.7.10.1
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg01521
EGFR tyrosine kinase inhibitor resistance
ptg01522
Endocrine resistance
ptg01524
Platinum drug resistance
ptg04010
MAPK signaling pathway
ptg04012
ErbB signaling pathway
ptg04020
Calcium signaling pathway
ptg04066
HIF-1 signaling pathway
ptg04151
PI3K-Akt signaling pathway
ptg04510
Focal adhesion
ptg04520
Adherens junction
ptg04530
Tight junction
ptg05200
Pathways in cancer
ptg05205
Proteoglycans in cancer
ptg05206
MicroRNAs in cancer
ptg05212
Pancreatic cancer
ptg05213
Endometrial cancer
ptg05215
Prostate cancer
ptg05219
Bladder cancer
ptg05223
Non-small cell lung cancer
ptg05224
Breast cancer
ptg05226
Gastric cancer
ptg05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102961961 (ERBB2)
04012 ErbB signaling pathway
102961961 (ERBB2)
04066 HIF-1 signaling pathway
102961961 (ERBB2)
04020 Calcium signaling pathway
102961961 (ERBB2)
04151 PI3K-Akt signaling pathway
102961961 (ERBB2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
102961961 (ERBB2)
04520 Adherens junction
102961961 (ERBB2)
04530 Tight junction
102961961 (ERBB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102961961 (ERBB2)
05206 MicroRNAs in cancer
102961961 (ERBB2)
05205 Proteoglycans in cancer
102961961 (ERBB2)
05230 Central carbon metabolism in cancer
102961961 (ERBB2)
09162 Cancer: specific types
05212 Pancreatic cancer
102961961 (ERBB2)
05226 Gastric cancer
102961961 (ERBB2)
05219 Bladder cancer
102961961 (ERBB2)
05215 Prostate cancer
102961961 (ERBB2)
05213 Endometrial cancer
102961961 (ERBB2)
05224 Breast cancer
102961961 (ERBB2)
05223 Non-small cell lung cancer
102961961 (ERBB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
102961961 (ERBB2)
01524 Platinum drug resistance
102961961 (ERBB2)
01522 Endocrine resistance
102961961 (ERBB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptg01001
]
102961961 (ERBB2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
ptg04147
]
102961961 (ERBB2)
04090 CD molecules [BR:
ptg04090
]
102961961 (ERBB2)
Enzymes [BR:
ptg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102961961 (ERBB2)
Protein kinases [BR:
ptg01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
102961961 (ERBB2)
Exosome [BR:
ptg04147
]
Exosomal proteins
Exosomal proteins of breast cancer cells
102961961 (ERBB2)
CD molecules [BR:
ptg04090
]
Proteins
102961961 (ERBB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Pkinase
Furin-like
TM_ErbB1
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
102961961
NCBI-ProteinID:
XP_015394617
LinkDB
All DBs
Position
Un
AA seq
1240 aa
AA seq
DB search
MKLRLPASPETHLDMLRHLYQGCQVVQGNLELTYLHANASLSFLQDIQEVQGYVLIAHNQ
VRQVPLQRLRIVRGTQLFEDNYALAVLDNGDPLDSGTPATGAALGGLRELQLRSLTEILK
GGVLIQRNPQLCHQDTILWKDIFHKNNQLALMLIDTNRSRACQPCSPACKDSHCWGASSG
DCQSLTRTVCAGGRRRPRLQACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGA
SCVTACPYNYLSTDVGSCTLVCPLNNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREA
RAVTSANIQEFVGCKKIFGSLAFLPESFEGDPASNTAPLQPEQLRVFEALEEITGYLYIS
AWPDSLPNLSVFQNLRVIRGRVLHDGAYSLTLQGLGISWLGLRSLRELGSGLALIHRNSR
LCFVHTVPWDQLFRNPHQALLHSANRPEDECAGEGLACYPLCAHGHCWGGGPTQCVNCSQ
FLRGQECVXXXXRGTRGRAGGAAGVGHGGSFQTPSSAIPSVRLPREYVKDRFCLPCHPEC
QPQNGSVTCLGSEADQCVACAHYKDPPFCVARCPSGVKPDLSFMPIWKFADEEGTCQPCP
INCTHSCADLDEKGCPAEQRASPVTSIIAAVVGILLVVVVGLVLGILIKRRRQKIRKYTM
RRLLQETELVEPLTPSGAMPNQAQMRILKETELRKVKVLGSGAFGTVYKGIWIPDGENVK
IPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLL
DHVREHRGRLGSQDLLKDCQGMHLGGLSSAGGMSYLEDVRLVHRDLAARNVLVKSPNHVK
ITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGA
KPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKGWMIDSECRPRFRELVAEFSRMA
RDPQRFVVIQNEDLGPASPLDSTFYRSLLEDEDMGDLVDAEEYLVPQQGFFCPDPAPGAG
GTAHHRHRSSSTRSGGGELTLGLEPSEEEPPKSPLAPSEGAGSDVFDGDLGMGAAKGLQS
LSPQDPSPLQRYSEDPTVPLPPETDGYVAPLTCSPQPEYVNQPEVWPKPPSPLEGPLPPS
RPAGATLERPKTLSPKALSPGKNGVVKDVFAFGGAVENPEYLAPRGRAAPQPHPPPAFSP
AFDNLYYWDQDTSERGSPPSTFEGTPTAENPEYLGLDETV
NT seq
3723 nt
NT seq
+upstream
nt +downstream
nt
atgaagctgcggctcccagccagtcccgagacccacctggacatgctccgccacctctac
cagggctgtcaagtggtacagggtaacctggagctcacctacctgcatgccaatgccagc
ctctccttcctgcaggatattcaggaggtgcaaggctatgtgctcattgcccacaaccaa
gtgagacaggtcccactgcagaggctacgaatcgtgcgaggcacccagctctttgaggac
aactacgccctggccgtgctggacaacggagacccactggacagtggcacccctgctaca
ggggctgccctaggagggctgcgggagctgcagctccgaagcctcacagagatcctgaag
ggaggggtcctcattcagcggaacccgcagctctgccaccaggacacgattctgtggaag
gacatcttccacaagaacaaccagctggccctcatgctgatagacaccaaccgctctcgg
gcctgccaaccctgttctccagcttgtaaagactcccactgctggggagcaagttccggg
gactgtcagagcttgactcgaactgtctgtgctggcggccggcgccgcccccgcctccag
gcctgcctccacttcaaccacagtggcatctgtgagctgcactgcccagccctggtcacc
tacaacacggacaccttcgaatccatgcccaaccctgagggccgttataccttcggtgcc
agctgtgtgactgcctgtccctacaactacctgtctacggacgtgggatcctgcaccctg
gtctgtcccctgaacaaccaagaggtgacagctgaggatggaacacagcggtgtgagaaa
tgcagcaagccctgtgcccgagtgtgctacggcctaggcatggagcacctgcgggaggcg
agggcagtcaccagtgccaacatccaagaatttgtcggctgcaagaagatctttgggagc
ctggcgtttctgccagagagctttgagggggacccagcctccaacactgcccccctgcag
cctgagcagctcagagtgtttgaggctctggaggagattacaggttacctgtacatctca
gcgtggccagacagcttgcctaacctcagtgtcttccagaacctcagagtgatccggggc
cgagttctgcatgacggtgcttactcgctgacccttcaagggctgggcatcagctggctg
gggctgcgttcgctgcgggagctgggcagtgggctggccctcatccaccgcaactctcgc
ctctgcttcgtacacacggtgccctgggaccagctcttccggaacccccaccaggccctg
ctccacagcgccaaccggccagaggacgagtgcgcgggtgagggcctggcctgctacccg
ctgtgtgcccacgggcactgctggggtgggggacccacccagtgtgtcaactgcagccag
ttccttcgaggccaggagtgtgtggnnnnnnnnngcaggggtacgcggggcagggcagga
ggggcggccggagtggggcacgggggctccttccagaccccctcctcagccatcccttct
gtcaggcttccccgggagtatgtgaaggataggttctgtctgccatgccacccagagtgt
cagccccagaatggctcagtgacctgcttgggctcggaagctgaccagtgtgtggcctgt
gcccactacaaggaccctcctttctgtgtggctcgctgccccagtggggtgaaacctgac
ctctccttcatgcccatctggaaatttgcagatgaggagggcacgtgccagccatgcccc
atcaactgcacccactcctgtgcggacctggacgagaagggctgccccgccgagcagaga
gccagccctgtgacgtccatcattgctgctgtggtgggcattctgctggtcgtggttgtg
gggctggtccttggcatcctaatcaagcgaaggcggcagaagatccggaagtacacgatg
cggaggctgctgcaggagacggagctggtggagcccctgacgcctagtggagccatgccc
aaccaggctcagatgcgaatcctgaaagaaacagagctgaggaaggtgaaggtgcttgga
tccggagcttttggcactgtctacaagggcatctggatccctgatggggaaaatgtgaaa
atcccagtggccatcaaagtgttgagggaaaatacatctcccaaagccaacaaagaaatc
ttggacgaagcgtatgtgatggctggcgtgggctccccatatgtgtctcgccttctgggc
atctgtctgacatccaccgtgcagttggtgacacagcttatgccttatggctgcctctta
gaccatgtccgagaacaccgtgggcgcctaggctcccaggacctgctgaaagattgccaa
ggtatgcacttagggggcctgagctctgcaggtgggatgagctacttggaggatgttcgg
ctcgtgcacagggacctggctgcccggaacgtgctggtcaagagtcccaaccacgtcaag
attacagattttgggctggctcggctgctggacattgacgagacagagtaccatgccgat
gggggcaaggtgcccatcaagtggatggcgctggagtccattctccgccggcggttcacc
catcagagtgacgtgtggagctacggtgtgactgtatgggaactgatgacttttggggcc
aaaccttatgatgggatcccagcccgggagattcctgacctgctggagaagggggaacgg
ctgccccagccccccatctgcaccattgatgtctacatgatcatggtcaagggttggatg
atagactctgaatgtcggccacgtttccgggagttggtggctgaattctcccggatggcc
agggacccccagcgctttgtggtcatccagaatgaggacttgggcccagccagtcccttg
gacagcactttctaccgttcactgctggaggatgaggacatgggagacctggtggacgct
gaggagtacctggtaccccagcagggtttcttctgcccagaccctgccccaggcgccggg
ggcacagcccaccacagacaccgcagctcatccaccaggagtggcggtggtgagctgaca
ctggggctggagccctccgaggaagagcctcccaagtctccactggcaccctcagaaggg
gctggctctgatgtgtttgatggcgacctgggaatgggggcagccaaggggctgcagagc
ctttccccacaggaccccagccctctacagcggtacagtgaggatcctaccgtaccccta
ccccctgagactgatggctacgttgcccccctgacctgcagtccccagcctgaatacgtg
aaccagccagaggtgtggccaaagcccccatcgcccttagaaggccctctgcctccttct
cgacctgccggtgccactctggaaaggcccaagactctgtcccccaaggctctttccccc
ggcaagaatggggttgtcaaagacgtttttgcctttgggggtgctgtggagaaccccgag
tacttggcaccccggggcagggctgcccctcagccccaccctcctccagccttcagccca
gcctttgacaacctctattactgggaccaggacacatctgagcggggctctccacccagc
acctttgaagggacccctacagcagagaaccccgaatacctgggcctggatgagacagtg
tga
DBGET
integrated database retrieval system
