Puma yagouaroundi (jaguarundi): 121023849
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Entry
121023849 CDS
T07555
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
pyu
Puma yagouaroundi (jaguarundi)
Pathway
pyu00350
Tyrosine metabolism
pyu00790
Folate biosynthesis
pyu01100
Metabolic pathways
pyu04728
Dopaminergic synapse
pyu04917
Prolactin signaling pathway
pyu05012
Parkinson disease
pyu05030
Cocaine addiction
pyu05031
Amphetamine addiction
pyu05034
Alcoholism
Module
pyu_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
pyu00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
121023849 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
121023849 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
121023849 (TH)
09156 Nervous system
04728 Dopaminergic synapse
121023849 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
121023849 (TH)
09165 Substance dependence
05030 Cocaine addiction
121023849 (TH)
05031 Amphetamine addiction
121023849 (TH)
05034 Alcoholism
121023849 (TH)
Enzymes [BR:
pyu01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
121023849 (TH)
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Paralog
GFIT
Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
121023849
NCBI-ProteinID:
XP_040321968
LinkDB
All DBs
Position
Unknown
AA seq
494 aa
AA seq
DB search
MPTPNAASPQAKGFRRAVSELDAKQAEAIMSPRFIGRRQSLIEDARKEREKAEAAGAASS
EPGDPLETTVFKEKDGKATLNLIFTLRGAKASLSRAVKAFETFEAQIRHLETRPAQRPRA
GGPHLEYFVCCEVPSVDLPALLSSVRRVAEDVRGARENKVFWFPRKVSELDKCHHLVTKF
DPDLDLGHPGFSDQAYRQRRKLIAEIAFQYKHGDPIPRVEYTAEEIATWKEVYTTLKGLY
VTHACREYLEAFQLLERFSGYREDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASL
AFRVFQCTQYIRHASSPMHSPEPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEI
EKLSTLYWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHSLSEEPEIRAFDPDAAAVQPYQ
DQTYQPVYFVSESFSDAKDKLRNYASRIQRPFSVKFDPYTLAIDVLDSPHAIRRSLQGVQ
DELHTLTHALSAIG
NT seq
1485 nt
NT seq
+upstream
nt +downstream
nt
atgcccactcccaacgccgcctcgccgcaggccaagggcttccgcagggccgtctccgag
ctggacgccaagcaggccgaagccatcatgtccccgcgcttcatcgggcgacggcagagc
ctcatcgaggacgctcgcaaggagcgagagaaggcagaggccgcgggggccgcctcctcg
gagcccggggaccccctggagaccacagtgttcaaggagaaggacggaaaggccacgctc
aacttgatcttcaccctgcggggcgccaaagcctcactgtcccgggccgtgaaggcgttc
gagacgtttgaggcccaaatccggcacctggagacccggccggcccagaggccgcgcgca
gggggcccccacctggaatactttgtgtgctgtgaggtgcccagcgtggacctgcccgcc
ctgctcagctccgtgcgccgggtggctgaggacgtgcggggcgccagggagaacaaggtc
ttctggttcccaaggaaagtttccgagctggacaagtgccaccacctggtcaccaagttt
gaccctgacctggacttgggtcacccgggtttctccgaccaggcgtaccggcagcgcagg
aagctgatcgccgagatagccttccagtacaagcatggcgaccccattccccgtgtggag
tacacggccgaggagatcgccacctggaaggaggtctacaccaccctcaagggcctctac
gtcactcacgcctgccgggaatacctggaggctttccagctgctggagcgtttcagtggg
taccgggaggacagcatccctcagctggaagacgtgtcccgcttcctgaaggagcggaca
ggcttccagctgcggcccgtggccggcctgctgtccgcccgggacttcctggccagcctg
gccttccgagtgttccagtgcacccagtacatccgacacgcctcctcgcccatgcactcc
ccggagccggactgctgccacgagctgctggggcacgtgcccatgctggccgaccgcacc
ttcgctcagttctcccaggacatcgggctcgcgtccttgggggcttccgacgaggagatt
gagaagctgtccacgctgtactggttcacggtggagttcgggctgtgcaaacagaatggg
gaggtgaaggcctacggtgctggactgctgtcctcctacggggagctcctgcactctctg
tctgaggagcccgagatccgggccttcgacccggatgctgcagccgtacagccttaccag
gaccagacttaccagcccgtctacttcgtgtccgagagtttcagcgacgccaaggacaaa
ctcaggaactatgcttcccgcatccagcgccccttctccgtgaagtttgacccgtacacg
ctggccatcgacgtgctggacagtccccatgccatccggcgctccctgcagggcgtccag
gacgagctgcacaccctcacccatgcgctgagcgccatcggctag
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