Sorex araneus (European shrew): 101541321 Help Entry 101541321         CDS       T07854                                  Symbol TH Name (RefSeq) tyrosine 3-monooxygenase   KO K00501   tyrosine 3-monooxygenase [EC:1.14.16.2] Organism sara  Sorex araneus (European shrew) Pathway sara00350   Tyrosine metabolism sara00790   Folate biosynthesis sara01100   Metabolic pathways sara04728   Dopaminergic synapse sara04917   Prolactin signaling pathway sara05012   Parkinson disease sara05030   Cocaine addiction sara05031   Amphetamine addiction sara05034   Alcoholism Module sara_M00042   Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline Brite KEGG Orthology (KO) [BR:sara00001]  09100 Metabolism   09105 Amino acid metabolism    00350 Tyrosine metabolism     101541321 (TH)   09108 Metabolism of cofactors and vitamins    00790 Folate biosynthesis     101541321 (TH)  09150 Organismal Systems   09152 Endocrine system    04917 Prolactin signaling pathway     101541321 (TH)   09156 Nervous system    04728 Dopaminergic synapse     101541321 (TH)  09160 Human Diseases   09164 Neurodegenerative disease    05012 Parkinson disease     101541321 (TH)   09165 Substance dependence    05030 Cocaine addiction     101541321 (TH)    05031 Amphetamine addiction     101541321 (TH)    05034 Alcoholism     101541321 (TH) Enzymes [BR:sara01000]  1. Oxidoreductases   1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen    1.14.16  With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor     1.14.16.2  tyrosine 3-monooxygenase      101541321 (TH) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Biopterin_H TH_ACT TOH_N Motif Other DBs NCBI-GeneID:  101541321 NCBI-ProteinID:  XP_004603172 LinkDB All DBs Position Unknown AA seq 519 aa AA seqDB search MPTPGTGAPQAKGFRRAVSELDSKQAEAIMSPRFIGRRQSLIQDARKEREKAEAAAAEPG EPPEVAPLQERDGRASLALLFSLRGPKPSPLSRVLKAFETFEATIQHLESRRASKPRAGD AGLDFFVRCEVRGADLPALLSSLRRVADDVRGAREQKALWFPRKVSELDRCHHLVTKFDP DLDLDHPGFSDQAYRQRRKLIAEIAFQYKHGDPIPRVEYTAEEVATWKEVYRTLKGLYAT HACREHLQAFELLERCSGYAEDHIPQLEDVSRFLKERTGFXXXPVTSIHAPRSALARSNM PPTVRPTPSHPLSRPRRDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTL YWFTVEFGLCKQNGEVKAYGAGLLSSYGELLHCLSEEPEVRAFDPEEAAVQPYQDQTYQS VYFVSESFSDAKDKLRSYAARIQRPFSVRLDPYTLSIEVLDSPRAVRRSLGGVQDELHTL AHSETLTSLRDPPCPTLRDLSPPSEIMGYLRDPSHTQRP NT seq 1560 nt NT seq  +upstreamnt  +downstreamnt atgcccacccccggcaccggcgcgccccaggccaagggcttccgcagggccgtctcggag ctggactccaagcaggccgaggccatcatgtctccccgcttcatcggccgccggcagagc ctcatccaggatgcacgcaaggagcgagagaaggcagaggcggcggcggctgagccaggg gagccccccgaggtggcgccccttcaggagcgggacggccgggccagcctcgctctgctc ttcagcttgcggggacccaagccctccccgctgtcccgtgtcctcaaggccttcgagacc tttgaggcgaccatccagcacctggagtcgcggcgggcgtccaagccacgggcaggggac gcggggctggacttcttcgtgcgctgcgaggtccggggcgctgacctgccggcgctgctc agctccctgcgccgggtggcagacgacgtgcggggtgccagggagcagaaggccctctgg ttcccgaggaaggtgtccgagctggaccggtgtcaccatctggtcaccaagttcgaccct gacctggacttggatcacccgggcttctcggaccaggcataccgccagcgccggaagctg atcgccgagatcgccttccagtacaagcacggcgaccccatcccacgcgtggagtacacg gccgaggaggtcgccacctggaaggaggtgtaccgcacgctcaaggggctctacgccacg cacgcctgccgcgagcacctgcaggccttcgagctgctggagcgctgcagcggctacgca gaggaccacatcccgcagctggaggacgtgtcccgcttcctgaaggagaggacgggcttc cnnnnnntccctgtcacatctatccacgccccccggtccgccttagcacgctccaacatg cccccaaccgtgcggcccaccccgtcccaccccctctcccgcccacgcagggactgctgc catgagctgctgggacacgtgcccatgctggccgaccggacctttgcgcagttctcccag gacattggcctggcatccctgggggcttcggacgaggagattgagaagctgtccacgctc tactggttcacggtggagttcggactgtgcaagcagaacggcgaggtgaaggcgtacggc gcggggctgctgtcgtcctacggggagctgctgcactgcctgtcggaggagcccgaggtg cgcgccttcgaccccgaggaggcggccgtgcagccgtaccaggaccagacctaccagtcc gtgtacttcgtgtccgagagcttcagcgatgccaaggacaagctcaggagctacgcggcg cgcatccagcgtcccttctccgtgcggctggacccgtacacgctgagcatcgaggtgctg gacagcccccgcgctgtgcggcgctccctggggggcgttcaggatgagctgcacacccta gctcactcagaaacccttacctccctcagagaccctccctgccccaccctcagggatctt tcccccccctcagaaatcatgggatacctcagagatcctagccacactcagagaccctga

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