Streptococcus iniae SF1: K710_0606
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Entry
K710_0606 CDS
T02686
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sik
Streptococcus iniae SF1
Pathway
sik00300
Lysine biosynthesis
sik00550
Peptidoglycan biosynthesis
sik01100
Metabolic pathways
sik01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sik00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
K710_0606
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
K710_0606
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
K710_0606
Enzymes [BR:
sik01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
K710_0606
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AGM98385
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Position
574062..575441
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AA seq
459 aa
AA seq
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MKLTLHEIAKVVDAENAISEFEDVPLGQIEFDSRKITKGDLFLPLKGLRDGHDFIDIAFE
NGAVATFSEKVISNKPYILVKDTLVAFQKLAQYYIEKMRLDVIAVTGSNGKTSTKDMIEA
VLSTTYKTYKTQGNYNNEIGLPYTVLHMPDDTEKIVLEMGQDHLGDIHLLSEIAKPHIAV
VTLIGEAHLEFFGSRDKIAEGKMQITDGMDSDGILIAPGDAIIDPYLPDNQMIIRFGPHQ
EIFVEDVVEEKTGLTFTTNVLKEKVKLPLAGKFNASNAMVAAYVGKLLAVTDEDIIEALE
TVSLTKNRTEWLKAANGADILSDVYNANPTATRLILESFSSISANPNGKKIALLADMKEL
GEDSVALHSQLVSSLNPNLITDLVFYGDDIEELAQLASQIYPINKVHFFRKDKEIDQFEA
LCQHVKALVESTDQILLKGSNSMNLERLVDALVTTRSSR
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atgaaattaacattacatgaaatagcgaaggttgtggatgcagaaaatgccatctcagag
tttgaagacgttcccctgggacaaatcgaatttgatagcagaaaaatcactaaaggggac
ctttttttgcccttaaaaggcttacgagatgggcatgattttattgatattgcctttgaa
aatggtgctgtggcaaccttctcagagaaagtaattagtaacaagccttatattttagtg
aaagacaccttagtggctttccaaaaattagctcagtattatattgaaaaaatgcgtctc
gacgttattgcagtgactggctcaaatggtaaaaccagtacaaaggacatgattgaggct
gtgctttcaaccacttataaaacctataaaacacaaggtaactataataatgaaattggc
ttgccttatacggtactgcatatgcctgatgatacagaaaaaattgtcctagaaatggga
caagaccatttgggtgatattcatctcttatcagaaattgccaagcctcacattgcagtt
gtaaccttaatcggtgaagcccatttagaattttttggcagtcgagataagattgcagaa
ggcaaaatgcaaatcacagatggtatggattcagacggcattttaattgccccaggtgat
gcaatcattgatccttatcttccagacaatcaaatgattatccgttttggaccgcatcag
gagatttttgttgaagatgttgtggaagaaaaaactggattaaccttcacaactaatgtg
cttaaagagaaggtcaaacttcctttggcaggtaaatttaatgccagtaatgctatggta
gcagcctatgttggtaaactattagctgtaactgatgaagacattattgaagcattagag
acggtctctttaaccaaaaatcgtacagaatggttgaaagctgctaatggagcagatata
ttatcagatgtctacaatgccaatccaacagcgacacgattgattttagaaagtttttct
agcatttcagcaaatcctaatgggaaaaaaatagccctattagctgatatgaaagaatta
ggagaagactcagtagctcttcactcacaattagtcagttctttgaatcctaaccttatt
actgaccttgttttttatggagacgatattgaagagttggcgcaattagccagtcaaatc
taccccattaataaagtgcatttctttagaaaagataaggagattgatcaatttgaagcc
ctttgccaacatgttaaggcattagttgaatcaactgatcaaatcttacttaaaggaagt
aactcaatgaaccttgagcgacttgttgatgctttagtgacaacaagatcatcacgatag
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