Thermostichus lividus: BRW62_12325
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Entry
BRW62_12325 CDS
T05303
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
slw
Thermostichus lividus
Pathway
slw00300
Lysine biosynthesis
slw00550
Peptidoglycan biosynthesis
slw01100
Metabolic pathways
slw01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
slw00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
BRW62_12325
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
BRW62_12325
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
BRW62_12325
Enzymes [BR:
slw01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
BRW62_12325
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Motif
Pfam:
Mur_ligase_M
Mur_ligase
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ATS19386
UniProt:
A0A2D2Q4E8
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All DBs
Position
2609581..2610939
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AA seq
452 aa
AA seq
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MLPFNRSKAVKTTLAAIAQALGQTGDWPEQPVTGISTDSRHVAAGNVFVALRGDTFDGHQ
FVAQAATAGATALIVEEPVVSQLPQLQVANTLAAYQRLGQWWRKQCRAAIIAITGSVGKT
TTKEMIAAVLRHYGRVLKTEANFNNEIGVPKTLLQLEPAHDFAVIEMGMRSPGEIALLSQ
IAQPDVAVITNVGTAHIGRLGSREAIAAAKCELLAEMPATSTAILNADTPLLLETASRVW
SGTTLTYGLTAGQHRGVYLPPHTLQIGDHAYTVPLAGAHHALNFLAALTVLRALGLNPQA
LPPQLELHLPAGRGGRYRLEPDILLLDETYNAGLESMVAALQLLRSLPGQRHLAVLGAMR
ELGDFSLPFHQQVGATVAQLGLDGLLILDEGAEGKALAQGAATVPSQQFASHGGLVEYLL
THLQRGDRVLFKASHAVALDRVVAELRQRWPR
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
ctgctcccatttaaccggagcaaggctgtgaagacaacgctggcggcgatcgcccaagct
cttggtcaaacgggggactggccagagcaacccgtgaccggcattagtacagattcgcgc
cacgtggctgctggcaatgtctttgtggcactgcggggagatacctttgatgggcatcag
tttgtggcgcaggcggcaacagcaggggcaactgccctgattgtggaggaacctgtcgtt
agtcagcttccccaattgcaggtggccaatacccttgctgcgtaccaacgcttagggcag
tggtggcgcaagcagtgccgcgcagccattattgccattactggctccgtgggtaaaacc
accactaaggaaatgattgcggccgtcctccgtcactacggcagggttcttaaaactgag
gccaacttcaacaatgagattggcgttcccaaaaccctcctgcaattagaacctgcgcat
gactttgcagtgattgaaatggggatgcgatcgcccggggagattgccctcctcagccaa
attgcccagcccgatgtagcggtgattacgaacgttggcacagcccacattggccgcctt
ggatcccgggaagccattgctgcggccaagtgcgaactcctggccgaaatgcccgccacc
agcaccgcgatactgaatgccgatactcctctcctattagaaacagccagtcgcgtctgg
tcaggaacaaccctcacctacggtttaaccgccggtcagcaccgcggggtctatttgccg
ccccataccctccagataggggatcacgcctacacagttccccttgccggtgctcaccat
gccctcaactttttggcagccttaacggttctcagggcgctggggctgaatcctcaagcg
ttgccaccgcagctagagctacacttgcccgcggggcgaggtggccggtatcggctagaa
ccagatattcttttactggatgaaacctacaatgctggcctcgaatccatggtggcggca
ctccagctcctgcgtagcctgcccggacagcggcatttggcggtgctgggtgcgatgcga
gagctaggggacttctcgcttccctttcatcaacaggtgggggcaacggtcgcccagttg
gggctcgatgggttattgattttagatgagggcgctgaagggaaagcccttgcccaagga
gcagcaacggtgccaagccagcaatttgctagccatgggggcttagtggagtatttattg
acccatttgcaacggggcgatcgcgtgctgtttaaggcctcccatgccgttgccttggat
cgcgttgtggcagaactgcggcaacgttggccgcgttga
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