Streptomyces spinosirectus: LXH13_34725
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Entry
LXH13_34725 CDS
T08958
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sspn
Streptomyces spinosirectus
Pathway
sspn00300
Lysine biosynthesis
sspn00550
Peptidoglycan biosynthesis
sspn01100
Metabolic pathways
sspn01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sspn00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LXH13_34725 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LXH13_34725 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LXH13_34725 (murF)
Enzymes [BR:
sspn01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LXH13_34725 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
UIR21884
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Position
complement(7586926..7588284)
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AA seq
452 aa
AA seq
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MTYSEPDFLSLGEIAAAVGGAVVGDGSVKVTAPAVLDGRRAEPGGLFVAFAGEHADGHDF
AQQAGRAGASAVLGSRPTPLPTVVVEDAQAALQALAAHVVARLRDRLSVIGLTGSQGKTG
TKDQVAAVLSSAAPTVATTGSLNNELGVPLTMLRAEAATRFLVLEMGARHVGDIALLTGL
VAPDIAVVLNVGQAHLGTFGSRAAIARAKGELVRGLAPGGTAVLNADDPRVVAMRSLTDG
PVLTFGRAEHADVRVAGLTLDRLGRPSFTLLTADTSVPVTLPHVGAHQALNASAAAAVGL
AAGVPLDATAAALATASLSSWRMELRELPCGAMLVDDSYNANPDSTRAALDALAAIEGRR
RIAVLGPMLELGDASEAEHRAVGEYAASRADVVATVGEAARPIADGAGERAVTLADNNAA
VDWLGDRIATGDVVLVKASRGAHLDEVAAALG
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
atgacctacagcgaaccagactttctcagcctcggtgagatcgccgccgcggtcggcggg
gcggtcgtgggcgacggcagtgtgaaggtgaccgcgcctgcggtgctcgacggtcggcgg
gccgagccgggcggcctcttcgtcgccttcgccggcgagcatgccgacggccacgacttc
gcccaacaggcaggccgggcaggtgcgtcggccgtgctcggttcgcgtcccacgccgctg
cccaccgtcgtcgtcgaggacgcccaggccgcgctgcaggcactcgccgcccatgtcgtg
gcccggctgcgcgaccggctgtccgtgatcgggctgaccggctcccagggcaagaccggc
accaaggaccaggtggcggccgtactgtcgagcgccgcgccgacggtcgccacgaccggc
tcgctcaacaacgaactcggcgtaccgctcacgatgttgcgcgccgaagcggccacccgg
ttcctggtcctggagatgggggcccgtcatgtcggggacatcgccctgctcaccggcctg
gtcgcgccggacatcgccgtcgtcctcaacgtgggtcaggcccacctcggcaccttcgga
tcgcgtgcggccatcgccagggccaagggcgagctggtgcgcgggctggcgcccggcggc
accgccgtcctcaacgccgacgatccgcgggtggtcgcgatgcgctcgctcacggacggc
ccggtgctgaccttcggccgggcggaacatgccgacgtacgggtcgccggcctgacgctg
gaccggctgggccgcccgtccttcacgctgctgaccgcggacacctcggtccccgtcaca
ctgccgcacgtgggtgcccaccaggcgctcaacgcctcggccgcggcagcggtgggactg
gcggccggcgtacccctcgacgcgacggccgcggcgctggccaccgcctcgctgtcgagt
tggcgcatggagctgcgcgaactcccgtgcggggcaatgctggtcgacgactcctacaac
gccaaccccgactcgacccgggccgccctggacgccttggcggcgatcgagggcaggcgc
cgcatcgccgtcctcggcccgatgctcgaactgggcgacgcgagtgaagccgagcaccgc
gcggtcggggagtacgccgcctcccgggccgacgtggtggccacggtcggcgaggccgcc
cggccgatcgccgacggcgcgggcgagcgggcggtgacactggccgacaacaacgcggcc
gtggactggctgggcgaccgcatcgctaccggagacgtggtgctggtcaaggcctcccgc
ggggcgcacctcgatgaagtcgcggccgcactcgggtag
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