KEGG   Trichechus manatus latirostris (Florida manatee): 101349700
Entry
101349700         CDS       T05135                                 
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 4
  KO
K04430  mitogen-activated protein kinase kinase 4 [EC:2.7.12.2]
Organism
tmu  Trichechus manatus latirostris (Florida manatee)
Pathway
tmu04010  MAPK signaling pathway
tmu04012  ErbB signaling pathway
tmu04620  Toll-like receptor signaling pathway
tmu04664  Fc epsilon RI signaling pathway
tmu04668  TNF signaling pathway
tmu04912  GnRH signaling pathway
tmu04926  Relaxin signaling pathway
tmu04935  Growth hormone synthesis, secretion and action
tmu04936  Alcoholic liver disease
tmu05132  Salmonella infection
tmu05135  Yersinia infection
tmu05142  Chagas disease
tmu05161  Hepatitis B
tmu05166  Human T-cell leukemia virus 1 infection
tmu05167  Kaposi sarcoma-associated herpesvirus infection
tmu05169  Epstein-Barr virus infection
tmu05208  Chemical carcinogenesis - reactive oxygen species
tmu05417  Lipid and atherosclerosis
tmu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:tmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    101349700
   04012 ErbB signaling pathway
    101349700
   04668 TNF signaling pathway
    101349700
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    101349700
   04664 Fc epsilon RI signaling pathway
    101349700
  09152 Endocrine system
   04912 GnRH signaling pathway
    101349700
   04926 Relaxin signaling pathway
    101349700
   04935 Growth hormone synthesis, secretion and action
    101349700
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    101349700
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    101349700
   05161 Hepatitis B
    101349700
   05167 Kaposi sarcoma-associated herpesvirus infection
    101349700
   05169 Epstein-Barr virus infection
    101349700
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    101349700
   05135 Yersinia infection
    101349700
  09174 Infectious disease: parasitic
   05142 Chagas disease
    101349700
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    101349700
   05418 Fluid shear stress and atherosclerosis
    101349700
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    101349700
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:tmu01001]
    101349700
Enzymes [BR:tmu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     101349700
Protein kinases [BR:tmu01001]
 Serine/threonine kinases: STE group
  STE7 family
   101349700
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like Pkinase_fungal Seadorna_VP7 ABC1 Haspin_kinase Choline_kinase YrbL-PhoP_reg APH
Other DBs
NCBI-GeneID: 101349700
NCBI-ProteinID: XP_023586753
UniProt: A0A2Y9R594
LinkDB
Position
Unknown
AA seq 390 aa
MPPYTAFGFHRFYVNELELISFTLGFQINFCEKAQSKRKALKLNFANPPFKSTARFTLNP
NPTGVQNPHIERLRTHSIESSGKLKISPEQHWDFTAEDLKDLGEIGRGAYGSVNKMVHKP
SGQIMAVKRIRSTVDEKEQKQLLMDLDVVMRSSDCPYIVQFYGALFREVGMNYLGFKFFY
ENVHSGNRAPSDSSGVVAKRDFFMETVKALNHLKENLKIIHRDIKPSNILLDRSGNIKLC
DFGISGQLVDSIAKTRDAGCRPYMAPERIDPSASRQGYDVRSDVWSLGITLVCLYQLKPC
HNNVTIRNIEMKENLIRLSCFLRTGSFSPTRDSMYYKSLTKDESKRPKYKELLKHPFILM
YEERTVEVACYVCKILDQMPATPSSPMYVD
NT seq 1173 nt   +upstreamnt  +downstreamnt
atgccgccttacacagctttcggctttcacaggttttacgtaaatgaactggaacttatc
tcttttactttaggctttcagataaacttctgtgaaaaggcacaaagtaaacgcaaagca
ctgaagttgaattttgcaaatccacctttcaaatcaacagcaaggtttactctgaatccc
aatcctacaggagttcaaaacccacacatagagagactgagaacacacagcattgaatca
tcaggaaaactgaagatctcccctgaacaacactgggatttcactgcagaggacttgaaa
gaccttggagaaattggacgaggagcttatggttctgtcaacaaaatggtccacaaacca
agtgggcagataatggcagttaaaagaattcggtcaacagtggatgaaaaagaacaaaaa
caacttcttatggatttggatgtagtaatgcggagtagtgattgcccatatattgttcag
ttttatggtgcactcttcagagaggtaggaatgaactatttgggttttaaatttttttat
gaaaacgttcatagtggtaaccgggcaccatccgattcttctggtgtcgtggcaaagagg
gattttttcatggagactgtgaaagcactaaaccacttaaaagaaaacttgaaaatcatt
cacagagatatcaaaccttccaatattcttctggacagaagtggaaatattaaactctgt
gactttggcatcagtggacagcttgtggattccattgccaagacaagagatgctggatgt
aggccatacatggcgccggaaagaatagacccaagtgcatcacgacaaggatatgatgtc
cgctctgatgtctggagtttggggatcacattggtatgtttatatcaacttaaaccctgt
cataataatgtgacaataagaaatatagaaatgaaagaaaatttaatcagactttcttgc
ttcctaagaactggttctttttctcccacacgtgacagtatgtattacaagagccttaca
aaggatgaatccaaaaggccaaagtataaagaacttctgaaacatccctttattttgatg
tatgaagaacgtaccgtagaggtcgcatgctatgtttgtaaaattctggatcaaatgcca
gctactcccagctctcccatgtatgtcgattga

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