Vulpes lagopus (Arctic fox): 121472267
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Entry
121472267 CDS
T07435
Symbol
TH
Name
(RefSeq) tyrosine 3-monooxygenase isoform X1
KO
K00501
tyrosine 3-monooxygenase [EC:
1.14.16.2
]
Organism
vlg
Vulpes lagopus (Arctic fox)
Pathway
vlg00350
Tyrosine metabolism
vlg00790
Folate biosynthesis
vlg01100
Metabolic pathways
vlg04728
Dopaminergic synapse
vlg04917
Prolactin signaling pathway
vlg05012
Parkinson disease
vlg05030
Cocaine addiction
vlg05031
Amphetamine addiction
vlg05034
Alcoholism
Module
vlg_M00042
Catecholamine biosynthesis, tyrosine => dopamine => noradrenaline => adrenaline
Brite
KEGG Orthology (KO) [BR:
vlg00001
]
09100 Metabolism
09105 Amino acid metabolism
00350 Tyrosine metabolism
121472267 (TH)
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
121472267 (TH)
09150 Organismal Systems
09152 Endocrine system
04917 Prolactin signaling pathway
121472267 (TH)
09156 Nervous system
04728 Dopaminergic synapse
121472267 (TH)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
121472267 (TH)
09165 Substance dependence
05030 Cocaine addiction
121472267 (TH)
05031 Amphetamine addiction
121472267 (TH)
05034 Alcoholism
121472267 (TH)
Enzymes [BR:
vlg01000
]
1. Oxidoreductases
1.14 Acting on paired donors, with incorporation or reduction of molecular oxygen
1.14.16 With reduced pteridine as one donor, and incorporation of one atom of oxygen into the other donor
1.14.16.2 tyrosine 3-monooxygenase
121472267 (TH)
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Motif
Pfam:
Biopterin_H
TH_ACT
TOH_N
LTP_2
Motif
Other DBs
NCBI-GeneID:
121472267
NCBI-ProteinID:
XP_041579442
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Position
11:complement(69921205..69928539)
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AA seq
533 aa
AA seq
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MPTPNTASPQAKGFRRAVSELDAKQAEAIMVRGLLVARGTGSAEYTGGSEPGWGRPRAGG
AGRALSPQSPRFIGRRQSLIEDARKEREKAEAASAASSEPGDLLEAAVSKEKDGKAMLNL
LFTLRGAKTSSLSRAVKAFETFEAQIHHLETRPSQRPRAGGPHLEYFVRCEVPSADLPAL
LSSVRRVAEDVRGARENKVLWFPRKVSELDKCHHLVTKFDPDLDLDHPGFSDQVYRQRRK
LIAEIAFQYKHGDPIPRVEYTAEEIATWKEVYTTLKSLYVTHACREHLEAFQLLERFSGY
REDSIPQLEDVSRFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSP
EPDCCHELLGHVPMLADRTFAQFSQDIGLASLGASDEEIEKLSTLYWFTVEFGLCKQNGE
VKAYGAGLLSSYGELLHSLSEEPEIRAFDPDAAAVQPYQDQTYQSVYFVSESFSDAKDKL
RNYASRIQRPFSVKFDPYTLAIDVLDSPHAIRRSLEGVQDELHTLAHALSAIG
NT seq
1602 nt
NT seq
+upstream
nt +downstream
nt
atgcccactcccaacaccgcctcgccgcaggccaagggcttccgcagggctgtctcggag
ctggacgccaagcaggccgaagccatcatggtaagggggctgctggtggccagagggacc
ggaagtgcagagtacaccggtgggtcagaaccgggatgggggcgaccgagggctggggga
gctgggcgtgccctgtccccgcagtccccgcgcttcatcgggcggcgccagagcctcatt
gaggacgcacgcaaggagcgagagaaagcagaggccgcgtcagctgcctcctcggagcct
ggagacctcctggaggccgcggtgtccaaggagaaggacgggaaggccatgctgaacttg
ctcttcaccctgcggggcgccaagacctcttcgctgtcccgagccgtgaaggcatttgag
acgtttgaagcccaaatccaccatctggagacccggccctcccagaggccacgggcaggg
ggcccccacctggagtactttgtgcgctgtgaggtgcccagtgctgacctgcccgccctg
ctcagctccgtgcgccgggtggcagaggatgtgcgtggtgccagggagaacaaggtcctc
tggttcccaaggaaagtttctgagctggacaagtgccaccatctagtcaccaagtttgac
cctgacctggacttggatcatccgggcttctcggaccaggtgtaccgccagcgcaggaag
ctgattgcagagatcgcattccaatacaagcatggtgaccccattccccgagtggagtac
acggccgaggagattgccacctggaaggaggtctacaccaccctgaaaagcctgtatgtg
acccatgcctgccgggagcacctggaggccttccagctgctggagcgcttcagcgggtac
cgtgaggacagcatcccccagctggaggacgtgtcccgcttcctgaaggagcggacaggc
ttccagctgcggcccgtggccggtctgctgtccgcaagggacttcctggccagcctggcc
ttccgagtgttccagtgcacgcagtacatccggcacgcgtcctcacccatgcactccccc
gagccggactgctgtcatgagctgctggggcacgtgcccatgctggctgaccggaccttc
gctcagttttcccaggacatcgggcttgcgtccttgggggcttccgatgaggaaattgag
aagctgtccacgctgtactggttcacagtggagttcgggctgtgcaagcagaatggtgag
gtgaaggcctatggcgctgggctgctgtcctcctacggggagctcctgcactccctgtct
gaggagcctgagatccgggccttcgacccagacgctgcggccgtgcagccttaccaggac
cagacctaccagtcggtctactttgtgtctgaaagtttcagcgatgccaaggacaagctc
aggaactacgcttcccgcatccaacgccccttctccgtgaagttcgacccatatacgctg
gccatcgacgtgctggacagtccccacgccatccggcgctcgctggagggggtccaggac
gagctgcacaccctcgcccatgcgctcagcgccatcggctag
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