Xenopus tropicalis (tropical clawed frog): 100144721
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Entry
100144721 CDS
T01011
Symbol
kmt2b
Name
(RefSeq) histone-lysine N-methyltransferase 2B
KO
K14959
[histone H3]-lysine4 N-trimethyltransferase MLL4 [EC:
2.1.1.354
]
Organism
xtr
Xenopus tropicalis (tropical clawed frog)
Pathway
xtr00310
Lysine degradation
xtr01100
Metabolic pathways
Brite
KEGG Orthology (KO) [BR:
xtr00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
100144721 (kmt2b)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
xtr03000
]
100144721 (kmt2b)
03036 Chromosome and associated proteins [BR:
xtr03036
]
100144721 (kmt2b)
Enzymes [BR:
xtr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.354 [histone H3]-lysine4 N-trimethyltransferase
100144721 (kmt2b)
Transcription factors [BR:
xtr03000
]
Eukaryotic type
Zinc finger
CXXC CpG-binding proteins
100144721 (kmt2b)
Chromosome and associated proteins [BR:
xtr03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
100144721 (kmt2b)
HMT complexes
MLL3/MLL4 complex
100144721 (kmt2b)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
SET
FYRC
FYRN
zf-CXXC
PHD
zf-HC5HC2H
zf-HC5HC2H_2
PHD_2
Bromodomain
Motif
Other DBs
NCBI-GeneID:
100144721
NCBI-ProteinID:
XP_002940678
Xenbase:
XB-GENE-853845
UniProt:
A0A7D9NJW2
A0A803KLM4
LinkDB
All DBs
Position
7:complement(128930764..128966710)
Genome browser
AA seq
2817 aa
AA seq
DB search
MAAAAASAGPGASGSVRGRFPGRPWVGRSGSRAERVRVPFQVSAEAACSENPDSAQLQIL
GLHRNLKRLKGACGRDSDSGEEDFVGFTAEESALGSSLRLALRSNRGKTPDPAPTSSLPS
AAPPRKPLCSIPPSLRHIFTPEKEVRVHLTQLDPSLFNMAKYSTIITRPKKEEVPIGLER
QNSPADPSTGAEHKLYTAEPPKQKGRPQRARVRTWKARASEAFRHHSQTDHSDPSQEETK
CCDEGNATDNCDAPSAATDKTDEQEELNDRKRTLTSQVIAPSELEGTLCRREGHASNAQV
LEKDLPASPNKACPAFREGQGDTQVPRVKWKLWADYKQENELETGASEADVTANDTAYGG
NMDLPLPEEGLQSKEALPSGPTDRLLCPEAEGLQASECLEREERNQSDGCGTGEEHKADI
DCGSEGLLLPHHEDSSGFPASVLAAEETSVLDVNSTNENAGFILAAEPPALPDSSSVPRN
KRVKKLSNSKKAKILRAKKAEQMAAKRLLAKIKEANIKAQPYMQAQSSKRTAPRNKSNVA
PVANARPSRVIKAPRRFLDEAQLSPFTENQTKSNPMLHNADILSSSLTEPEPEEISDPLP
SPTDTFFNLFSEDHLCFLPPLSPEAESTPSCPSSASSPTLVSLPPSLSESKRKNILRAPT
FCWNSVGTAEQEAPSTLCSSRPLFRLQSPASPLEPLQLNLPLSAPSSPPPQPVPKLEPKR
SPLLRAPQFTPSEAHLKIYESVSFEDRDGKVPFSPLLSNRQHHTDFTSSATASVCTTETM
SAPAAKQSDLNVGGRRANHLTIPMFDSTLEKGDGLETNLLVTEPTLKPSDQILSDPVETL
NSGYNRIGKLEMGAIKLGPVDSPGVVCKMAIKSPSLSPTDTLGEIGISSAVNDQTLSGTD
KKVISLLEKAKLQLIRIDKQKNSELGQDSPVQGPRIKHVCRHPSVALGQPRAMIPEDIPR
LSALPLHEREPPAPSSIAQPEESSSASEPESSTVKQKRAAPVRSKPKPPTKARLRMGRCG
TCKGCLVQDDCGKCINCKDKTKFGGPNTKKQCCVFRQCDAILARRLERAGKKGRKAPAPP
RENLPDSDDNYPDTWRAEETEANDPDSLSQRKSSRRCVRQRPFYDLFPDSEDSDYDPGPR
VSRKKTRRESDLLPQESEEQSKPRRTPQQPLILRARKGPEQESIMNGGSGKLKSADGTYR
LRVDFKEDCDLQNVWLMGGLSVLTSVPVNPTLMCLLCASRGRHKLLYCQVCCEPFHRFCL
EESERPLPNQEGTWCCRRCKFCNVCGQKGKAKKPLLECELCQTNYHVNCLGPNYPLKAPR
SGKGWTCSACIRCRSCGIAPGKDGDLELTEDSKLCSECSTLYDKGNFCPICIRCYEESEY
ESKMIQCAKCDKWIHSKCEGLSDEGYELLSNLPDSVVYTCPPCLGNSSPIWKEAMLSELT
AGLHEVLQGLLALDPAASLLHCAQCSASDGGTKCQHGPCDLQSLRQLLEDGHYSSVSTFN
DNVAYIIQKGMKQENCGSGFDGNALKSLYLKSMEKSFSWFNAEESEHWQTNRKMETKGIL
PNAVLPPSSDHNYANWRIKKEDPPSKGVVQKATSPPKVKLESDAEPAGEIKTDTRQCALC
LKYGDDDPKDAGRLLYIGQNEWTHINCAIWSAEVFEENDGSLKNVHAAVARGRQLRCDNC
QKIGATVGCCLSTCHSNFHFMCARASRCCFQDDKKMFCSKHTKLLDGTPVEEDCFDVLRR
VYVDFEGISFRRKFLQGLEPDHIHMMIGSMKIDSLGMLNDLSVTEGKIYPVGYQCSRLYW
STQDARRQCWYKCRVLEHCPNSGETHPEGGEGQEQNKTIVHSPGPLPDPTEMEAAFSPPL
PADTSSSCGQPPPLQPNTSATAPRSFIGARMKTPNYSPSRRPLGGSSRPLPSPGSPTSSS
LSHHILTVSDPEVTPLRRTRRPVPPSRFNAPSSTRSPEETTSPSPLPARPVIRHRATSEN
EVPTPASCGGASEVEVMSSSDGGALLGPCGAQLIVGSEGDSSSEEDADDQYYGLTRTVVS
GDKISSMPASASSVHIRQLDGIHDSTDSEDGSQGPCGPIGGGKTPSHIPSEIVEFVLKNT
GNSESSIQLHHIGPPASVASSSSSSSAQNGDATLLSNGNGAVSRQPSQGPPPLRDPPQLQ
RVCHPLISVPTKNTYDAPPVSVNVPTPKVILLNKMGQVLVKVENGNAEQPLLRETSKAER
VTALALPKLPAVKHVKVAPKNAKNPLSGLPHPQPTPLSPSMNTVILQATSSINPGQSWTL
STPVVRVVPMLNVMQGTGQITLGTQALMTPAITGIPQTCLLQNVPINSGVLSVASSVQPQ
QPQLKPAPQPQARLQVQPQLSVLQPTPVKVVSLPSLCLKRPPLPSSTCFPVKKPKLEQTD
GPKVGDKTDISVISSSVVLSADPASSSVAGTRLNRARIKAPMVQEVLDLTSLKDEEQSLN
DGLFIDLTLAVKDEDSQEETPVDSPSLAPPLEYIPNFENEEEKKSSVPRRDGPYLRFEIT
SEDGFYIQADSAEDAWKAVLEKVQETRGVGKLRHLSLSASMIGTRMFGVQHDAVLFLLEQ
LTGAERCRGYKFLFHPQEVEEGEISTNPSGCARSEVYVRKSTFDMFNFLASQHRTLPEIG
PCEEEEEEVQLKSTRRATSLDLPMAMRFRHLKKTSKEAVGVYRSAIHGRGLFCKRNIDAG
EMVIEYSGIVIRSVLTDKREKFYDSKGIGCYMFRIDDFDVVDATMHGNAARFINHSCEPN
CYSRVIHVEGQKHIVIFALRSIYRGEELTYDYKFPIEDASNKLPCNCGAKKCRRFLN
NT seq
8454 nt
NT seq
+upstream
nt +downstream
nt
atggcggcggctgcggcctcggctggtcccggagcctcgggctcggtgcggggccgcttt
ccgggccggccgtgggttggacgcagcgggagccgggcggagcgggttcgtgtgcctttc
caggtgtcggctgaggcggcgtgctccgagaacccggactcggctcagctgcagatactc
gggctgcaccggaacctgaagcggctgaagggggcctgcggccgggacagtgacagcggc
gaggaagactttgtcggtttcactgctgaagaaagtgcgcttggaagttccctccgattg
gctctgagatcaaacagaggtaaaacgcctgacccagcaccgacaagctctctgccgagc
gcagcaccgcccagaaagccactatgttccataccaccaagcctaaggcatatttttacc
cctgagaaagaggtccgtgtgcatctcacgcagctcgatccgtcattgtttaatatggca
aagtactcgaccattattacccggcccaagaaggaagaggtccctattggcctggaaagg
cagaactcgcctgcagatcccagcacaggagcagaacacaagctatacaccgctgaaccc
ccaaaacagaaagggaggcctcagagggcaagggttcgcacgtggaaggcaagagcctca
gaggctttccgtcaccacagccaaacagaccactcggaccccagccaagaagaaaccaaa
tgttgcgatgaaggcaacgcaactgataattgtgatgctccttccgctgcgactgacaaa
acagacgagcaggaagagttaaatgatagaaaaaggactctgaccagtcaggttattgcc
ccttctgaactggaaggtactctgtgtagaagagaagggcacgcgagcaacgcccaagtg
ttggagaaggatttacctgcctcaccaaataaggcttgtcctgctttcagagaaggacag
ggggacacccaggttcctagagtaaaatggaagctttgggcagattataagcaagagaac
gagctggaaactggcgcttcagaagcagacgtgactgcgaatgataccgcgtatgggggc
aacatggacttgcctttgccggaggaaggtctacaaagcaaagaagctctcccttctggc
ccaacagacagactactgtgtccagaagcagagggcctgcaggcaagtgaatgtctggaa
agggaagaaagaaatcagtcagatggctgtggtactggggaagagcataaagcagacata
gactgtgggtctgagggactgttgctacctcaccatgaagatagttctggctttcctgca
tctgttttggctgctgaggaaacttctgtgctggatgtaaactccaccaatgagaacgct
ggtttcattttggcagcggaacctcctgctttgccagattcctcctctgtcccccgcaac
aagagagtcaagaagttaagcaatagcaaaaaagcaaagatattgcgcgccaagaaggct
gaacaaatggccgccaaacgcctgctggcaaaaataaaggaggcgaatattaaagcccag
ccctatatgcaagctcagtcttccaagaggacggcaccaaggaacaagagcaacgtggcg
cccgtggctaatgcccgcccctcccgggtcattaaagcacctcggcggtttctcgatgag
gcgcagttatctccttttacagaaaaccaaaccaagtccaacccaatgttgcacaacgct
gatatccttagtagcagcttgaccgaaccggagccggaagaaatatctgatccgcttcct
tctcccacagacacgtttttcaatctgtttagtgaagatcatctgtgtttcctacctccc
ctctcacctgaggcagaatccacgccctcctgcccttcgtctgcgtcttctcctacttta
gtgtctcttcctccgtctctttctgagagcaagcggaagaatattctccgggcgccgacc
ttctgttggaattcagttggcaccgctgagcaggaagccccgtctaccctgtgctcctct
agacctctctttcgcctgcagtctcctgcctctccactagagccgttacaactcaacttg
ccgctgtctgctccatcctccccaccgcctcagccggttcccaaattggaacctaaaagg
tctccccttctccgtgccccgcagttcactcccagtgaagcacatctgaagatctatgaa
tcggtgtccttcgaggaccgggatggcaaagtacctttttcccctcttctttctaaccga
cagcatcacaccgacttcacttcaagtgcaaccgccagtgtgtgtacaacagaaaccatg
agtgcgccggcggccaaacagagtgatctaaacgtaggaggccgccgggcaaaccatctc
actatacctatgtttgattctacattagagaaaggggatggtctagaaacgaatttgttg
gtcaccgaaccgactctaaaaccatctgatcaaattctctccgatccagttgagacacta
aactccgggtacaacaggatcgggaaacttgaaatgggagccattaagttaggacctgtg
gacagccctggggtggtatgtaaaatggctatcaaatcgccatcactctcgcctacagac
acccttggagaaataggaatatcttctgcggtgaacgaccagaccttgtcgggcaccgac
aaaaaagtcatttccctgctggagaaagccaagttgcagttaatacggattgacaagcaa
aagaactctgaattgggccaggattcaccagtgcagggtccacggattaaacacgtctgc
cggcacccatctgtcgcccttggacagcctcgagccatgattcctgaggacatccctaga
ctgagcgctttgccattgcacgagagagaaccccctgcaccctcctccatagctcagcct
gaagaatcttcctctgcctctgagccagaaagcagcacggtgaagcagaagagagctgct
ccagtacgcagcaagccaaagcccccgacgaaggcgagactccgtatgggccgctgcggc
acttgcaaaggctgcttagtgcaggatgattgtggcaagtgcatcaactgcaaggacaag
accaagttcgggggcccaaacacaaagaagcaatgctgtgtgtttcggcaatgtgacgct
attctggcgcggaggctggagagggcaggaaagaaaggtcgaaaagcaccagcgccacca
cgcgagaatctcccagactctgacgacaattacccagatacctggagggctgaggaaacg
gaagccaatgatcctgattcgctgtctcagcgcaagtcgtcccgacgctgtgtcaggcag
cgcccgttctacgatcttttccctgattccgaggactctgactacgaccccggccccaga
gtctcgcgcaagaagacacgccgagagtcagatctgctccctcaagagtccgaggaacag
agcaaacctcgcagaactccccagcagcctctgattcttagggctcgcaagggcccagag
caagaatccataatgaacggaggctctgggaaactgaaatctgcagatggaacttaccgg
ttacgggtcgatttcaaggaagactgtgatttgcaaaatgtgtggctgatgggaggactg
agtgtcctgacttctgttcctgtaaacccaacgctgatgtgcctgctgtgtgccagcagg
gggaggcataagcttctgtactgccaggtctgctgcgagcctttccataggttttgcttg
gaggaatcggaacggccgctgcccaatcaggaagggacgtggtgctgccggcgctgcaaa
ttctgtaacgtgtgcgggcagaagggaaaggcaaaaaagcccttgctagaatgtgagctg
tgccagacaaactaccatgtcaactgcctggggcccaattatcctctcaaagcgcctcgt
agtggcaaaggctggacctgctcggcctgcattcgctgtagaagttgtgggattgccccg
ggaaaagatggcgacctggaattaacggaagacagcaaactctgctcggagtgcagcacg
ctctacgacaagggaaacttctgtcccatttgtatccgttgctatgaggagagcgagtac
gagagcaaaatgatacaatgtgcaaagtgtgataaatggattcactccaagtgcgagggg
ctttctgatgaagggtatgagctactatccaacctacctgacagtgtggtgtacacttgc
cccccatgtctgggcaacagcagcccaatatggaaggaagccatgctttctgagctgact
gctgggctccacgaggtactgcagggattactggcgttggatcctgctgcttctctgcta
cattgtgcacagtgctcggctagtgacggtggcaccaaatgccagcacggcccatgtgac
ctccagtcgttacggcagctcttggaagacggtcactacagctcagtaagcacctttaac
gacaacgtggcctatatcatacagaaggggatgaagcaggaaaactgtggctctggattc
gacgggaatgcgctaaagagcttgtatttaaagagtatggagaaaagctttagctggttc
aacgcggaagagtcggaacactggcagaccaatcgcaagatggagaccaaaggcattctt
cctaacgctgttctgcctccttcctctgatcataactatgccaactggaggataaagaaa
gaggatccaccaagcaagggagtcgtccagaaagccacttccccgcccaaagttaagctg
gaaagtgacgcagaacctgccggagagataaagacggatacgcgtcagtgcgctctctgc
ctgaaatatggcgacgatgatccgaaggatgctgggagactgttatatattgggcagaac
gaatggacccacatcaactgcgctatatggtcagctgaggtttttgaggagaacgacggc
tctttaaaaaatgtgcacgctgctgtggctcgtgggaggcagttacgctgtgataattgc
cagaagatcggtgctaccgtcggctgctgcttatccacctgccatagcaatttccacttc
atgtgtgcccgggccagccgctgctgctttcaggatgacaaaaagatgttctgctcaaag
cacacaaagttacttgatggcacgccggtagaagaggactgcttcgatgtactgcgcagg
gtgtacgtggacttcgaagggatcagctttagaaggaagttccttcagggactggagcct
gaccatatccacatgatgattggttctatgaagattgacagtttgggaatgctcaatgat
ctgtccgtcactgaagggaagatttaccccgtgggatatcagtgctcgcgactctattgg
agcacacaggacgcgcggcgccagtgctggtacaaatgcagggtccttgaacactgcccc
aactccggagagacccaccctgagggaggggaggggcaggaacagaacaagaccattgtt
catagtcctgggcctttaccagatcccacagaaatggaagcagctttcagccctcctctt
cctgcagatacctcctcctcttgtgggcagcctccgcctcttcagcccaacaccagcgca
actgcaccccgctcttttataggtgcacgtatgaaaactccaaactactctccatcacgg
cggcctcttgggggttcatcccgtcccctaccttcaccagggagcccaacatcctcctca
ttatcgcaccatatcctcacagtcagtgatccagaagtgactccacttcgcaggactcgc
agaccagtcccaccttctagatttaatgccccatcatccactcgctctcccgaagaaact
accagcccgtccccgctcccagctcgcccagtgattcgacaccgcgctacgtctgagaac
gaggtgccgactccggcctcatgtggcggggccagcgaggtggaagtgatgtcatcgtca
gacgggggggcgctgttgggaccgtgcggcgcccaactgatcgtggggtcggagggcgac
agcagttcggaggaagatgccgatgaccagtactacggtttaacacggacagtcgtatct
ggtgataaaataagctctatgccggcctctgcatcctctgttcacatccggcagttagac
ggtatccatgacagcacggacagcgaggatggctcccagggtccctgtggccccattggt
ggaggcaaaactccttcccacattccttctgagattgtggaatttgtgcttaaaaacaca
gggaattccgagtctagcatccagctgcaccatattggtcctccggcatctgttgcctcc
tcttcttcttcctcttcagcacagaacggcgatgcgactctgctctctaacggcaatggt
gctgtatcccgccagccttcacaagggccgccccctcttagggaccccccacagctgcag
agagtctgtcacccgctaatatctgtgcctacaaagaacacttatgacgcccctccggtg
tcggtgaatgtgccgacgcccaaggttatattgctgaataagatgggtcaggtgctggtg
aaggtggagaatggaaacgcagagcagccgctgctgcgagagacttccaaagcagagcga
gtgactgctcttgcgctcccaaagcttcctgctgtaaaacatgttaaagtcgctccgaaa
aatgccaaaaaccctctctccggtcttcctcatccgcaacccacgccgctgtctccttcc
atgaacaccgttatcttgcaggctacgtcctccattaacccgggccagtcatggacgctg
agtacccctgtggtgcgcgtggtgccgatgctgaacgtcatgcagggtacggggcagata
actctgggcacccaggcacttatgaccccagcaatcactggaatccctcagacctgtcta
ctgcaaaatgtacccataaatagtggcgttttgagcgttgcttcctccgtgcaaccgcag
cagcctcagctgaaacctgccccgcaaccccaggcacgtctccaagtgcagccgcagctc
tcggtgctccagcccacgccggtcaaggtggtgtctcttccttccctttgtctcaagagg
ccacctttgcccagcagcacttgcttccctgtcaagaaaccaaaactggaacaaaccgat
ggacccaaagtgggggacaaaacggatatttctgtcataagtagttctgtggtgctaagt
gccgaccctgcctccagctcagtggccggcacaagattaaaccgggccaggatcaaggct
cccatggtgcaggaagtgctggatctcacctctctgaaagacgaagagcaaagtctgaat
gatgggctgtttattgatcttactctcgctgtgaaagatgaagactcccaagaggaaacc
ccagttgattctccttccttggcaccgcccttagaatacattccaaattttgagaacgag
gaagagaagaagagttctgtgccgaggagggacggcccctatctgcgctttgaaatcact
agtgaagacggattctacatccaggctgacagtgcagaagatgcgtggaaagctgttctg
gagaaggtgcaagagactcgcggtgtgggaaagctacgacatttgtccctttcggctagc
atgatcgggacacgcatgtttggagtccagcacgacgcagtccttttcctcctggagcag
ctgactggcgcggagcgatgccgtgggtacaaattcctctttcacccccaagaggtagaa
gaaggagaaatttccaccaacccctctggttgtgcccgcagtgaggtctatgtcaggaaa
tccaccttcgacatgtttaacttcctggcttcccagcaccgcacactgccggagattggg
ccctgcgaggaggaagaggaggaggtgcagctgaagtccaccaggcgcgccaccagtctg
gatctgcctatggcaatgcgcttccgccatctaaagaaaacatctaaagaggccgttgga
gtgtacaggtctgcaatccatggcaggggtttgttctgcaagagaaacatagatgcagga
gaaatggtgatagaatattccggcatcgttatccgttctgtactcactgataaaagagag
aagttttatgacagcaagggcatcgggtgctacatgttccgtatcgacgacttcgacgtg
gtggacgcgacgatgcacgggaacgcggcgagattcatcaaccactcgtgcgagccgaac
tgctactcccgggtcatccacgtggagggccagaagcacatcgtcatctttgcgctgcgc
agcatttaccgcggggaggagctgacctacgactacaagttccccattgaggacgccagt
aacaagctgccctgcaactgcggcgccaagaaatgcaggcggttcctcaactga
DBGET
integrated database retrieval system
