Yersinia pseudotuberculosis IP 32953 (serotype I): YPTB0684
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Entry
YPTB0684 CDS
T00195
Symbol
murF
Name
(GenBank) D-alanine:D-alanine-adding enzyme
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
yps
Yersinia pseudotuberculosis IP 32953 (serotype I)
Pathway
yps00300
Lysine biosynthesis
yps00550
Peptidoglycan biosynthesis
yps01100
Metabolic pathways
yps01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
yps00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
YPTB0684 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
YPTB0684 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
YPTB0684 (murF)
Enzymes [BR:
yps01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
YPTB0684 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
CAH19924
UniProt:
Q66EK9
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All DBs
Position
820430..821806
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AA seq
458 aa
AA seq
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MIKVSLRFLASLLNAEYIVAESVSDDIEITEVTIDTRKVTAGCLFVALKGERFDGHDFAE
DAIAAGAGALLVSKRLLVGGPQLVVKDTRLALGQFAAWVRQQVPARIVALTGSSGKTSVK
EMAAAILRQCGNVLYTAGNFNNDIGVPLTLLRLTAEHDFAVIELGANHVGEIAYTTDLSR
PESALVNNLAAAHLEGFGSLAGVAQAKGEIFAGLPANGTAIINADSNDWPHWQETLHNKR
VWRFSPHAAEHIDFYASDVRITPQLTSFTLHSPFGTVAIELPLPGQHNIANALAAAALAM
SVGADLAAVRQGLAQLQAVPGRLFPVPLAEGKLLLDDSYNANVGSMIAAAQVLAEMPGYR
VMVVGDMAELGETAADCHRQVGEAAKLAGVDKVLSVGTLSQILSSASGNGEHFQDQNTLS
TRVNALLNEYPVITVLIKGSRSAAMENVVRALQEKASC
NT seq
1377 nt
NT seq
+upstream
nt +downstream
nt
atgattaaggtctctctgcgttttctggctagcttacttaatgctgaatatatcgttgct
gaatcagtcagcgatgatattgagataactgaagtgaccattgatacccgtaaggtcact
gctggttgtctgtttgttgcgctgaaaggcgagcgttttgatgggcatgattttgccgaa
gatgctattgccgcaggtgctggcgctttgctggtaagtaaacgcttactggtggggggg
ccgcagttagttgtcaaagacacgcgcttggcgttagggcaatttgcggcttgggttcgc
cagcaagttccggctcggatagtggcattaaccggttcatcgggtaaaacctcggtaaaa
gaaatggcggcagcgattttgcgccaatgcggcaatgtgctgtataccgccggtaacttt
aataacgatatcggtgtcccgctaacattgctgcgcctaacggccgaacatgattttgct
gttattgaacttggtgccaaccatgttggtgaaattgcctacaccaccgatttaagccgt
ccagaaagcgctttggtgaataatttagccgccgctcatctggaggggtttggttcgctg
gccggtgtggcgcaagccaaaggtgagatcttcgctggcttgcctgccaatggcacggcg
attatcaatgccgatagtaacgactggccgcactggcaagaaacgctacataacaaacgg
gtttggcgtttctcgccccacgccgcagaacatattgatttctatgccagtgatgtgcgg
atcacgcctcaactcacctccttcactttgcattcaccgtttggcaccgtggctatcgaa
ttgcctctaccggggcagcataacatcgccaatgcgttagcggcggcagcattagccatg
tcggttggggcggatttagccgcagtacgccaagggttggcgcagttacaagcagtacct
ggccggttattccccgtcccattagcggaaggcaaattgctgttggatgacagctataac
gccaacgtgggttccatgattgccgccgcacaggtcttggccgagatgccgggttaccgg
gtgatggtggtcggtgatatggccgagttgggcgaaaccgcggcagattgccatcgtcag
gttggtgaagccgcgaaactcgcaggcgtcgataaagtattaagcgttggcacattgagc
cagatactgagcagtgcgagcgggaatggcgaacactttcaggatcaaaatacattgagc
acccgtgtaaacgcgttgctgaacgaatatccggttatcactgttttaattaaaggttca
cgtagcgccgctatggaaaatgtcgtgcgtgcgttacaggagaaggcatcatgttag
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