KEGG ORTHOLOGY: K21891

ORTHOLOGY: K21891

Entry

K21891                      KO

Symbol

TMCO1

Name

calcium load-activated calcium channel

Disease

H02415

Craniofacial dysmorphism, skeletal anomalies, and mental retardation syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K21891  TMCO1; calcium load-activated calcium channel
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K21891  TMCO1; calcium load-activated calcium channel
Membrane trafficking [BR:ko04131]
Endoplasmic reticulum (ER) - Golgi transport
  Others
   Multi-pass translocon (MPT) complex
    K21891  TMCO1; calcium load-activated calcium channel
Transporters [BR:ko02000]
Other transporters
  Pores ion channels
   K21891  TMCO1; calcium load-activated calcium channel

Other DBs

GO:

0005262

TC:

1.A.106.1

Genes

HSA:	54499(TMCO1)

PTR:	469565(TMCO1)

PPS:	100995569(TMCO1)

GGO:	101125379(TMCO1)

PON:	100172905(TMCO1)

NLE:	100600215(TMCO1)

HMH:	116473297(TMCO1)

MCC:	698272(TMCO1)

MCF:	101926540(TMCO1)

MTHB:

126941920

MNI:	105492966(TMCO1)

CSAB:

103230680(TMCO1)

CATY:

105598282(TMCO1)

PANU:

100998459 101019102(TMCO1)

TGE:	112622125(TMCO1)

MLEU:

105539561(TMCO1)

RRO:	104670184(TMCO1)

RBB:	108523250(TMCO1)

TFN:	117076688(TMCO1)

PTEH:

111539283(TMCO1)

CANG:

105505521(TMCO1)

CJC:	100415682(TMCO1)

SBQ:	101041966(TMCO1)

CIMI:

108308299(TMCO1)

CSYR:

103254157(TMCO1)

MMUR:

105860494(TMCO1)

LCAT:

123634928(TMCO1)

PCOQ:

105806399(TMCO1)

OGA:	100955111(TMCO1)

MMU:	68944(Tmco1)

MCAL:

110296384(Tmco1)

MPAH:

110322047(Tmco1)

RNO:	289196(Tmco1)

MCOC:

116096798(Tmco1)

ANU:	117716613(Tmco1)

MUN:	110551795(Tmco1)

CGE:	100758664(Tmco1)

MAUA:

101838049(Tmco1)

PROB:

127223535(Tmco1)

PLEU:

114689915(Tmco1)

MORG:

121455297(Tmco1)

MFOT:

126511275

AAMP:

119799545(Tmco1)

NGI:	103746123(Tmco1)

HGL:	101718305(Tmco1)

CPOC:

100732835(Tmco1)

CCAN:

109690343(Tmco1)

DORD:

105989621(Tmco1)

DSP:	122106094(Tmco1)

PLOP:

125360269(Tmco1)

NCAR:

124961824

MMMA:

107147250(Tmco1)

OCU:

100345773

OPI:	101524489(TMCO1)

TUP:	102481467(TMCO1)

GVR:	103601631(TMCO1)

CFA:	478992(TMCO1)

CLUD:

112643083(TMCO1)

VVP:	112914317(TMCO1)

VLG:	121471882(TMCO1)

NPO:	129515189(TMCO1)

AML:	100476373(TMCO1)

UMR:	103658221(TMCO1)

UAH:	113268694(TMCO1)

UAR:	123800137(TMCO1)

ELK:

111151022

LLV:

125085860

MPUF:

101671021(TMCO1)

MNP:	132025731(TMCO1)

MLK:	131814414(TMCO1)

NVS:	122918404(TMCO1)

ORO:	101364926(TMCO1)

EJU:	114210398(TMCO1)

ZCA:	113933626(TMCO1)

MLX:	118014054(TMCO1)

NSU:	110588124(TMCO1) 123324838

LWW:	102728759(TMCO1)

FCA:	101093523(TMCO1)

PYU:	121020931(TMCO1)

PCOO:

112864804(TMCO1)

PBG:	122475735(TMCO1)

PVIV:

125155857(TMCO1)

LRUF:

124509925

PTG:	102951640(TMCO1)

PPAD:

109276625(TMCO1)

PUC:

125925942

AJU:

106965576

HHV:	120224666(TMCO1)

BTA:	614715(TMCO1)

BOM:	102269039(TMCO1)

BIU:	109577804(TMCO1)

BBUB:

102403235(TMCO1)

BBIS:

104997307(TMCO1)

CHX:	102168400(TMCO1)

OAS:	101112778(TMCO1)

BTAX:

128045087(TMCO1) 128056502

ODA:	120855500(TMCO1)

CCAD:

122429787(TMCO1)

MBEZ:

129540626(TMCO1)

SSC:	100151809(TMCO1)

CFR:	102516322(TMCO1)

CBAI:

105068049(TMCO1)

CDK:	105092716(TMCO1)

VPC:	102540901(TMCO1)

BACU:

103019352(TMCO1)

BMUS:

118903941(TMCO1)

LVE:

103080131

OOR:	101269263(TMCO1)

DLE:	111169234(TMCO1)

PCAD:

102978199(TMCO1)

PSIU:

116754330(TMCO1)

NASI:

112397709(TMCO1)

ECB:	100058551(TMCO1)

EPZ:	103547345(TMCO1)

EAI:	106831127(TMCO1)

MYB:	102242931(TMCO1)

MYD:	102765356(TMCO1)

MMYO:

118673000(TMCO1)

MLF:	102427500(TMCO1)

PKL:	118721746(TMCO1)

EFUS:

103296503(TMCO1)

MNA:	107537947(TMCO1)

DRO:	112298780(TMCO1)

SHON:

118979152(TMCO1)

AJM:	119065444(TMCO1)

PDIC:

114511939(TMCO1)

PHAS:

123818389(TMCO1)

MMF:	118637855(TMCO1)

PPAM:

129081914(TMCO1)

HAI:	109385017(TMCO1)

RFQ:	117014733(TMCO1)

PALE:

102890719(TMCO1)

PGIG:

120617718(TMCO1)

PVP:	105301519(TMCO1)

RAY:	107512742(TMCO1)

TOD:	119241363(TMCO1)

SARA:

101548149(TMCO1)

SETR:

126013488(TMCO1)

LAV:	100659076(TMCO1)

TMU:

101358260

ETF:	101660061(TMCO1)

DNM:	101427245(TMCO1)

MDO:	100016856(TMCO1)

GAS:	123244067(TMCO1)

SHR:	100932792(TMCO1)

AFZ:

127562968

PCW:	110202728(TMCO1)

OAA:	100076851(TMCO1)

GGA:	427100(TMCO1)

PCOC:

116230471(TMCO1)

MGP:	100545894(TMCO1)

CJO:	107317245(TMCO1)

TPAI:

128072097(TMCO1)

LMUT:

125693341(TMCO1)

NMEL:

110402381(TMCO1)

APLA:

101800007(TMCO1)

ACYG:

106047782(TMCO1)

CATA:

118243560(TMCO1)

AFUL:

116492174(TMCO1)

TGU:	101233092(TMCO1)

LSR:	110478938(TMCO1)

SCAN:

103823371(TMCO1)

PMOA:

120512204(TMCO1)

OTC:	121344261(TMCO1)

PRUF:

121359760(TMCO1)

GFR:	102035313(TMCO1)

FAB:	101810746(TMCO1)

OMA:	130256172(TMCO1)

PHI:	102099834(TMCO1)

PMAJ:

107208325(TMCO1)

CCAE:

111922495(TMCO1)

CCW:	104695471(TMCO1)

CBRC:

103612703(TMCO1)

ETL:	114063534(TMCO1)

ZAB:	102074304(TMCO1)

ACHL:

103806599(TMCO1)

SVG:	106852272(TMCO1)

MMEA:

130583592(TMCO1)

HRT:	120756290(TMCO1)

FPG:	101919906(TMCO1)

FCH:	102049692(TMCO1)

CLV:	102087437(TMCO1)

EGZ:	104132053(TMCO1)

NNI:	104010384(TMCO1)

PCRI:

104025609(TMCO1)

PLET:

104627479(TMCO1)

EHS:	104514585(TMCO1)

PCAO:

104042776(TMCO1)

ACUN:

113482686(TMCO1)

TALA:

104364865(TMCO1)

PADL:

103914113(TMCO1)

AFOR:

103893981(TMCO1)

ACHC:

115348813(TMCO1)

HALD:

104322203(TMCO1)

HLE:	104840655(TMCO1)

AGEN:

126042173

GCL:

127018951

CCRI:

104160796(TMCO1)

CSTI:

104551350(TMCO1)

CMAC:

104484931(TMCO1)

MUI:	104543234(TMCO1)

BREG:

104630581(TMCO1)

FGA:	104071443(TMCO1)

GSTE:

104264387(TMCO1)

LDI:	104346794(TMCO1)

MNB:	103778623(TMCO1)

OHA:	104333741(TMCO1)

NNT:	104402410(TMCO1)

SHAB:

115611882(TMCO1)

DPUB:

104301537(TMCO1)

PGUU:

104459222(TMCO1)

ACAR:

104523150(TMCO1)

CPEA:

104392905(TMCO1)

AVIT:

104269174(TMCO1)

CVF:	104293414(TMCO1)

RTD:	128913602(TMCO1)

CUCA:

104058370(TMCO1)

TEO:	104383908(TMCO1)

BRHI:

104501583(TMCO1)

AAM:	106494039(TMCO1)

AROW:

112975022(TMCO1)

NPD:	112950403(TMCO1)

TGT:	104578433(TMCO1)

DNE:	112983697(TMCO1)

SCAM:

104142674(TMCO1)

ASN:	102388317(TMCO1)

AMJ:	102569885(TMCO1)

CPOO:

109307137(TMCO1)

GGN:	109287000(TMCO1)

PSS:	102457432(TMCO1)

CMY:	102933720(TMCO1)

CCAY:

125640872(TMCO1)

DCC:	119859740(TMCO1)

CPIC:

101931897(TMCO1)

TST:	117881236(TMCO1)

CABI:

116839899(TMCO1)

MRV:	120370382(TMCO1)

ACS:	100554945(tmco1)

ASAO:

132774306(TMCO1)

PVT:	110089741(TMCO1)

SUND:

121929233(TMCO1)

PBI:	103057695(TMCO1)

PMUR:

107301166(TMCO1)

CTIG:

120300241(TMCO1)

TSR:	106553467(TMCO1)

APRI:

131194860(TMCO1)

PTEX:

113448147(TMCO1)

NSS:	113425067 113425087

VKO:	123027995(TMCO1)

PMUA:

114598473(TMCO1)

PRAF:

128415163(TMCO1)

ZVI:	118078515(TMCO1)

HCG:	128325107(TMCO1)

STOW:

125433299(TMCO1)

EMC:	129331392(TMCO1)

XLA:	734689(tmco1.S)

XTR:	548724(tmco1)

NPR:	108798623(TMCO1)

RTEM:

120945532(TMCO1)

BBUF:

120979365(TMCO1)

BGAR:

122943956(TMCO1)

MUO:	115472776(TMCO1)

GSH:	117367637(TMCO1)

DRE:	378980(tmco1)

SRX:	107731247 107745794

SANH:

107668083 107695270

SGH:	107549116 107585891

CCAR:

109095162 109104872

CAUA:

113069934 113107228

CGIB:

127963452 128018743

PTET:

122350464(tmco1)

LROH:

127169693(tmco1)

OMC:	131545955(tmco1)

PPRM:

120483001 120483037(tmco1)

RKG:	130086194(tmco1)

MAMB:

125279354(tmco1)

CIDE:

127517569

MASI:

127415209 127424100

TROS:

130568206(tmco1)

TDW:	130439925(tmco1)

MANU:

129414199(tmco1)

IPU:

108265593

IFU:	128607962(tmco1)

PHYP:

113534450(tmco1)

SMEO:

124399966(tmco1)

TFD:	113655775(tmco1)

TVC:	132854059(tmco1)

CMAO:

118813736(tmco1)

EEE:	113581071(tmco1)

CHAR:

105900891(tmco1)

TRU:	101074230(tmco1)

TFS:	130528707(tmco1)

TNG:	GSTEN00013744G001

LCO:	104921744(tmco1)

TBEN:

117491024(tmco1)

CGOB:

115006550(tmco1)

PGEO:

117446024(tmco1)

GACU:

117559031(tmco1)

EMAC:

134869109(tmco1)

ELY:	117253634(tmco1)

EFO:	125896364(tmco1)

PLEP:

121941020(tmco1)

SLUC:

116063216(tmco1)

ECRA:

117949884(tmco1)

ESP:	116695441(tmco1)

PFLV:

114561372(tmco1)

GAT:	120823524(tmco1)

PPUG:

119216299(tmco1)

AFB:	129094334(tmco1)

CLUM:

117730123(tmco1)

PSWI:

130194002(tmco1)

MSAM:

119901225(tmco1) 119915249

SCHU:

122877976(tmco1)

CUD:	121511842(tmco1)

ALAT:

119028528(tmco1)

MZE:	101472931(tmco1)

ONL:	100699199(tmco1)

OAU:	116334449(tmco1)

OLA:	111947389(tmco1)

OML:	112150680(tmco1)

CSAI:

133457961(tmco1)

XMA:	102233968(tmco1)

XCO:	114151031(tmco1)

XHE:	116726386(tmco1)

PRET:

103464000(tmco1)

PFOR:

103139829(tmco1)

PLAI:

106936232(tmco1)

PMEI:

106928215(tmco1)

GAF:	122838344(tmco1)

PPRL:

129379699(tmco1)

CVG:	107091528(tmco1)

CTUL:

119787714(tmco1)

GMU:	124873448(tmco1)

NFU:	107387360(tmco1)

KMR:	108246252(tmco1)

ALIM:

106529307(tmco1)

NWH:	119407888 119407904(tmco1)

AOCE:

111576149(tmco1)

MCEP:

125009362(tmco1)

CSEM:

103398727(tmco1)

POV:	109625366(tmco1)

SSEN:

122780335(tmco1)

HHIP:

117759773(tmco1)

HSP:	118120714(tmco1)

SMAU:

118317951(tmco1)

LCF:

108878995

SDU:	111232027(tmco1)

SLAL:

111662618(tmco1)

XGL:	120790505(tmco1)

HCQ:	109516952(tmco1)

SSCV:

125975723

SBIA:

133503013(tmco1)

PEE:	133405915(tmco1)

PTAO:

133480300(tmco1)

BPEC:

110154789(tmco1)

MALB:

109965694(tmco1)

BSPL:

114853359(tmco1)

SJO:	128361440(tmco1)

SASA:

100195741(tmco1)

STRU:

115158684(tmco1)

OTW:	112251348(tmco1)

OMY:	100301839(tmco1)

OGO:	123996485(tmco1)

ONE:	115108628(tmco1)

OKI:	109902814(tmco1)

OKE:	118393547(tmco1)

SALP:

111976001(tmco1)

SNH:	120054982(tmco1)

CCLU:

121532797(tmco1)

ELS:	105005906(tmco1)

SFM:	108935424(tmco1)

PKI:	111834919(tmco1)

AANG:

118226583(tmco1)

LOC:	102694426(tmco1)

PSPA:

121294124 121327436

ARUT:

117409805 117417290

PSEX:

120514864(tmco1)

LCM:	102347798(TMCO1)

CMK:	103180029(tmco1)

RTP:	109913517(tmco1)

CPLA:

122554588(tmco1)

HOC:	132818670(tmco1)

LERI:

129701197(tmco1)

PMRN:

116944978(TMCO1)

LRJ:	133341841(TMCO1)

BFO:

BBEL:

CIN:

SCLV:

SPU:	100892898 115929176

LPIC:

APLC:

AJC:

SKO:

DME:	Dmel_CG10470(CG10470)

DER:

6549439

DSE:

6614636

DSI:	Dsimw501_GD24177(Dsim_GD24177)

DYA:	Dyak_GE13226

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI13086

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:	108376461 108378166

AOQ:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ004839

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:	107043468 107043469

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:	109538562 125503920

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_214154

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:

PGW:

CFEL:

CCRN:

API:

AGS:

RMD:

ACOO:

DVT:

DCI:

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM249110

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

IEL:

FCD:

DPX:	DAPPUDRAFT_303443

DMK:

116924969

DPZ:

124329978

PVM:	113802761 113814565

PJA:

PCHN:

PMOO:

HAME:

PCLA:

PTRU:

ESN:

MNZ:

HAZT:

EAF:

LSM:

TCF:

PPOI:

119095336 119095337 119095338

ISC:

DSV:

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_F22B5.10(F22B5.10)

CBR:

CBG_00622

CRQ:	GCK72_004978

BMY:	BM_BM3505(Bm3505)

LOA:	LOAG_18443

TSP:

Tsp_07776

HRO:	HELRODRAFT_156425

LGI:	LOTGIDRAFT_211578

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:	111122879 111123235

CANU:

OED:

MYI:

PMAX:

MCAF:

MMER:

RPHI:

DPOL:

OBI:

OSN:

LAK:

SMM:	Smp_203970

EGL:

NVE:

EPA:

ATEN:

ADF:	107330027 107354866

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_20690

AQU:

100634235

ATH:	AT3G12030 AT5G06660

ALY:	9307296 9318829

CRB:	17882845 17890842

CSAT:

104734676

EUS:	EUTSA_v10016091mg EUTSA_v10022159mg

BRP:

103845847

BNA:	106358225 106418496

BOE:

106318284

RSZ:	108806602 130504983

THJ:

104799285

CPAP:

110811744

CIT:

102618024

CIC:	CICLE_v10013918mg

PVY:

MINC:

TCC:

GRA:

GHI:	107889492 107891247

GAB:

HSYR:

DZI:

EGR:

GMX:	100499752 100782593

GSJ:

114390981

PVU:	PHAVU_001G097100g

VRA:

VAR:

VUN:

VUM:

CCAJ:

APRC:

MTR:

TPRA:

CAM:

PSAT:

VVO:

LJA:	Lj0g3v0284669.1(Lj0g3v0284669.1)

ADU:

107470259

AIP:

107604920

AHF:	112697031 112754919

LANG:

109335397

PCIN:

129290464

QSA:	O6P43_005817 O6P43_009458

FVE:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103449666 114824223

MSYL:

126594358 126617160

PXB:	103934222 103945701 103958714

ZJU:

MNT:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:

MESC:

POP:

PEU:

PALZ:

JRE:	108982718 109011931

CILL:

122276329 122279374

CAVE:

132192020

QSU:

112040854

QLO:	115951378 115951457 115951754 115970675 115980521

TWL:	119998213 120012243

VVI:

VRI:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

LBB:

NTA:

NSY:

NTO:

NAU:

INI:

ITR:

SIND:

OEU:

EGT:

SSPL:

SHIS:

APAN:

HAN:

ECAD:

LSV:	111905410 111913014

CCAV:

112510316 112522281

DCR:	108213195 108224311

CSIN:

114314346

RVL:

131322725

AEW:	130781290 130784668 130784723

BVG:

SOE:

CQI:

ATRI:

MOF:

NNU:

MING:

TSS:	122644554 122650058

PSOM:

113275373

OSA:

4333937

DOSA:

Os03t0721400-01(Os03g0721400)

OBR:

OGL:

BDI:

ATS:

TDC:	119283675 119294865

TAES:

123087064 123090900 123095929

TUA:

125550453

LPER:

127293118

LRD:	124700372 124700387

SBI:

8063362

ZMA:	100283298 100382332

SITA:

SVS:

PVIR:

PHAI:

PDA:	103705794 103712991

EGU:	105037400 105058656

MUS:

103968530

ZOF:	122019674 122023487 122041312 122045804

DCT:

PEQ:

AOF:

MSIN:

NCOL:

ATR:

SMO:	SELMODRAFT_74617 SELMODRAFT_87488

PPP:

112274256

CRE:	CHLRE_03g182900v5

VCN:	VOLCADRAFT_109592

MNG:

MNEG_3628

CVR:	CHLNCDRAFT_30102

APRO:

F751_0485

CME:	CYME_CMJ114C

CCP:	CHC_T00002767001

SRE:	PTSG_12755

DDI:	DDB_G0281489

DPP:	DICPUDRAFT_79372

DFA:

DFA_02024

EHI:	EHI_177610(20.t00041)

EDI:	EDI_049910

EIV:	EIN_018760

ACAN:

ACA1_109690 ACA1_392580

PFA:	PF3D7_1362300

PFD:	PFDG_03994

PFH:	PFHG_05291

PREI:

PRSY57_1361200

PGAB:

PGSY75_1362300

PYO:	PY17X_1139700

PCB:	PCHAS_1137800

PBE:	PBANKA_1138300

PVV:	PVVCY_1103940

PKN:	PKNH_1109000

PVX:	PVX_115070

PCY:	PCYB_111830

PMAL:

PREL:

TAN:

TPV:

TOT:	TOT_030000410

BEQ:	BEWA_013200

BMIC:

BMR1_01G01770

BBIG:

BBBOND_0404790

CPV:

cgd6_1490

CHO:	Chro.60186

TGO:	TGME49_310870

TET:	TTHERM_00382130

PTM:	GSPATT00006911001 GSPATT00039181001

PTI:	PHATRDRAFT_49185

FCY:	FRACYDRAFT_275769

TPS:	THAPSDRAFT_269110

NGR:	NAEGRDRAFT_38649

» show all

Reference

PMID:10393320

Authors

Iwamuro S, Saeki M, Kato S

Title

Multi-ubiquitination of a nascent membrane protein produced in a rabbit reticulocyte lysate.

Journal

J Biochem 126:48-53 (1999)
DOI:10.1093/oxfordjournals.jbchem.a022435

Sequence

[hsa:54499]

LinkDB

DBGET integrated database retrieval system